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The map label for this gene is lhr [C]

Identifier: 146299516

GI number: 146299516

Start: 2031140

End: 2033599

Strand: Direct

Name: lhr [C]

Synonym: Fjoh_1756

Alternate gene names: 146299516

Gene position: 2031140-2033599 (Clockwise)

Preceding gene: 146299515

Following gene: 146299517

Centisome position: 33.31

GC content: 38.62

Gene sequence:

>2460_bases
ATGAATAGGGACGAATTATATGTATTGGCCGAAAACTGGTTTAAAAGTCAGGGTTGGAAATCTTTTCCATTCCAGACGCA
AACCTGGACTGCTTTTCTGCAGGGAAAAAACGGTTTATTAAACGCTCCAACCGGAAGCGGAAAAACCTATGCCTTGTGGT
TTCCTGTAGTTCTCGATTACATAAAAAAAAATCCCGATTATAAAACCAAGCACAAAGCCGGATTAAAAGCCATTTGGATT
ACGCCTTTGCGGGCGCTATCTGTAGAAATAAAACAAGCAGCAGAACGAATTATTACCGATTTAGATCTGCCGTTAACCGT
AGGAATTCGTTCAGGAGATACTTCGCAAAGCGAAAGAGCCAGACAGAAAAACAAAATGCCCGATCTTTTAATTACAACGC
CCGAAAGTTTACAGCTTCTTTTGGCTTCAAAACAATATGAAAAAACGTTTGCCAACTGCGGTGCAATAATAGTTGATGAA
TGGCACGAATTAATGGGAACCAAACGAGGCGTTCAAATGGAATTGGCACTTTCGAGATTAAAAACAATTACACCAAAAAT
GCGAATCTGGGGAATTTCGGCAACAATTGGAAATCTCGAATTAGCACAAGAAGTTTTATTAGGGCATGATACGGAAGCCT
ATAAAAATTCAGTTTTGATAAAAGCACATATCAATAAAAAGATTAAGATAGAATCAATTCTGCCTGAGAAAATGGAAACT
TATCCGTGGCGCGGACACATGGGTTTGCATTTGATTGATGAGGTTGCGAAGATAATCCGAAAGAGCAAAACGACTTTAAT
TTTTACCAATGTACGTTCGGCCTGCGAAATTTGGTTTCAGGCCATTTTAGAAAAATATCCGGAATTTGCAGGAGAAATGG
CGATGCATCACGGAAGCATAAGCAGAGAAACCCGTTTGTGGGTGGAGGACGCCATTCGAAACGAAGAATTAAAAGTCGTA
GTCTGCACTTCGAGTTTAGATCTTGGTGTCGATTTTGCGCCTGTTGAAACCATTATTCAGGTTGGCGGACCAAAAGGTGT
TGCCAGATTTTTGCAGAGAGCAGGAAGAAGCGGGCACCAGCCGGGGAAAGAAAGCATGATTTATTTTCTCGCCACACATG
CAATGGAATTAATTGAAGCTTCGGCATTAAAAAAAGCGGTTGCCCAAACTGTTGTCGAAGATCGAATGCCGTATTTAAAC
AGTTGGGACGTTTTGGTTCAATATCTAAATACACTGGCAGTTTCTGACGGATTTTTTCCGGATGAAATTTATGAAGAAGT
TAAAACAACTTTCTGTTATCAAAATATAACCAAAGAAAACTGGAACTGGATTTTAAATTTCATTACCAACGGAAGTCAGA
GCTTGCAGGCTTACGACGAATTTAAAAAAGTAGAAATTGAAGCTGACGGGCGTTATAAAATCAACAGCCGTTTTATTGCC
ATGCATCATCGTATGCAAATGGGAACAATTGTGGGCGATGCGGTTTTGAATGTAAAATTTTTAAGCGGCGGTTTTATTGG
TACAATTGAAGAATGGTTTGCTTCGAAATTACAGAGAGGCGATGTTTTTACTTTTGCCGGAAGGCGCCTCGAATTGTTTC
AAATTAAAAACATGCAGGTTTTAGTTCGAAAAGCTGATCCTAAAAAAACAGCCAGAGTGGTAAGCTGGATGGGAGGCCGA
ATGACGTTATCAGCACAGATGAGTGAACTGCTTCGGGAAGAATTATATGCGGCAAATACAGATCATCTAACTCCTGAATT
AAAAGCTTTAAAACCTATTTTTGACAGGCAGAGAAAAGAAAGTATTGTACCCAATAACAATGAATTTTTAATCGAAACGT
TTAAAACAAGAGAAGGTTATCACGCTATTTTTTATCCATTTGAAGGACGTTATGTTCACGAAGCTATGGCAAGTTTAATT
TCGTATCGAATCAGTTTATTGTCGCCAATTACGTTTTCACTGGCCTATAACGATTACGGATTCGAATTGCTTTCTGATCA
GGAAATAGATATGCAGTCTGTTTTTGATAATAATTTGTTTACGACAGAATATGTACATCATGATTTGCAGAAAAGTTTAA
ACGCAACCGAAATGGCGCGCCGAAAATTTCGTGATATTGCCGTAATTGCTGGTTTGGTTTTTACGGGAATGCCCGGAAAA
CCTGTTAAAACAAAACATTTGCAAAGCGGTTCGCAATTGCTTTTTGAGGTTTTTAGAGATTATGAACCCGATAATTTATT
ATTACAGCAGGCTTATACAGAAACCTTTGAACATCAGTTAGAAGAAGGACGTTTGATTCAGGCAATGGAAAGAATAAACA
ATCAGGCGATTGTCTGGAAACAATGTAAAAAGCCAACGCCGTTTAGTTTTCCAATAATTACAGATCGTTTACGCGAAAAA
ATATCAAGTGAGACCCTGCAGGAAAGAATAAAGAAAATGACCGCGAGTTACATGAAATAA

Upstream 100 bases:

>100_bases
ACAAGTTTCTACTCATAGCTATGTTTGTTAATGCAAATGAAATGCCTTTATGCGTTTCTAAAAGCTATGTTTCTATGTGT
TAAAATTAATTATATCATGA

Downstream 100 bases:

>100_bases
ATTAATATGAGAATAAATATCAACAATCAAAATTTCGTTTTGCATCAGTCCGGTGCTGCTTTTTGGGAAGAAAAGAAAAT
TCTTTTTATTTCTGATTTGC

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 819; Mature: 819

Protein sequence:

>819_residues
MNRDELYVLAENWFKSQGWKSFPFQTQTWTAFLQGKNGLLNAPTGSGKTYALWFPVVLDYIKKNPDYKTKHKAGLKAIWI
TPLRALSVEIKQAAERIITDLDLPLTVGIRSGDTSQSERARQKNKMPDLLITTPESLQLLLASKQYEKTFANCGAIIVDE
WHELMGTKRGVQMELALSRLKTITPKMRIWGISATIGNLELAQEVLLGHDTEAYKNSVLIKAHINKKIKIESILPEKMET
YPWRGHMGLHLIDEVAKIIRKSKTTLIFTNVRSACEIWFQAILEKYPEFAGEMAMHHGSISRETRLWVEDAIRNEELKVV
VCTSSLDLGVDFAPVETIIQVGGPKGVARFLQRAGRSGHQPGKESMIYFLATHAMELIEASALKKAVAQTVVEDRMPYLN
SWDVLVQYLNTLAVSDGFFPDEIYEEVKTTFCYQNITKENWNWILNFITNGSQSLQAYDEFKKVEIEADGRYKINSRFIA
MHHRMQMGTIVGDAVLNVKFLSGGFIGTIEEWFASKLQRGDVFTFAGRRLELFQIKNMQVLVRKADPKKTARVVSWMGGR
MTLSAQMSELLREELYAANTDHLTPELKALKPIFDRQRKESIVPNNNEFLIETFKTREGYHAIFYPFEGRYVHEAMASLI
SYRISLLSPITFSLAYNDYGFELLSDQEIDMQSVFDNNLFTTEYVHHDLQKSLNATEMARRKFRDIAVIAGLVFTGMPGK
PVKTKHLQSGSQLLFEVFRDYEPDNLLLQQAYTETFEHQLEEGRLIQAMERINNQAIVWKQCKKPTPFSFPIITDRLREK
ISSETLQERIKKMTASYMK

Sequences:

>Translated_819_residues
MNRDELYVLAENWFKSQGWKSFPFQTQTWTAFLQGKNGLLNAPTGSGKTYALWFPVVLDYIKKNPDYKTKHKAGLKAIWI
TPLRALSVEIKQAAERIITDLDLPLTVGIRSGDTSQSERARQKNKMPDLLITTPESLQLLLASKQYEKTFANCGAIIVDE
WHELMGTKRGVQMELALSRLKTITPKMRIWGISATIGNLELAQEVLLGHDTEAYKNSVLIKAHINKKIKIESILPEKMET
YPWRGHMGLHLIDEVAKIIRKSKTTLIFTNVRSACEIWFQAILEKYPEFAGEMAMHHGSISRETRLWVEDAIRNEELKVV
VCTSSLDLGVDFAPVETIIQVGGPKGVARFLQRAGRSGHQPGKESMIYFLATHAMELIEASALKKAVAQTVVEDRMPYLN
SWDVLVQYLNTLAVSDGFFPDEIYEEVKTTFCYQNITKENWNWILNFITNGSQSLQAYDEFKKVEIEADGRYKINSRFIA
MHHRMQMGTIVGDAVLNVKFLSGGFIGTIEEWFASKLQRGDVFTFAGRRLELFQIKNMQVLVRKADPKKTARVVSWMGGR
MTLSAQMSELLREELYAANTDHLTPELKALKPIFDRQRKESIVPNNNEFLIETFKTREGYHAIFYPFEGRYVHEAMASLI
SYRISLLSPITFSLAYNDYGFELLSDQEIDMQSVFDNNLFTTEYVHHDLQKSLNATEMARRKFRDIAVIAGLVFTGMPGK
PVKTKHLQSGSQLLFEVFRDYEPDNLLLQQAYTETFEHQLEEGRLIQAMERINNQAIVWKQCKKPTPFSFPIITDRLREK
ISSETLQERIKKMTASYMK
>Mature_819_residues
MNRDELYVLAENWFKSQGWKSFPFQTQTWTAFLQGKNGLLNAPTGSGKTYALWFPVVLDYIKKNPDYKTKHKAGLKAIWI
TPLRALSVEIKQAAERIITDLDLPLTVGIRSGDTSQSERARQKNKMPDLLITTPESLQLLLASKQYEKTFANCGAIIVDE
WHELMGTKRGVQMELALSRLKTITPKMRIWGISATIGNLELAQEVLLGHDTEAYKNSVLIKAHINKKIKIESILPEKMET
YPWRGHMGLHLIDEVAKIIRKSKTTLIFTNVRSACEIWFQAILEKYPEFAGEMAMHHGSISRETRLWVEDAIRNEELKVV
VCTSSLDLGVDFAPVETIIQVGGPKGVARFLQRAGRSGHQPGKESMIYFLATHAMELIEASALKKAVAQTVVEDRMPYLN
SWDVLVQYLNTLAVSDGFFPDEIYEEVKTTFCYQNITKENWNWILNFITNGSQSLQAYDEFKKVEIEADGRYKINSRFIA
MHHRMQMGTIVGDAVLNVKFLSGGFIGTIEEWFASKLQRGDVFTFAGRRLELFQIKNMQVLVRKADPKKTARVVSWMGGR
MTLSAQMSELLREELYAANTDHLTPELKALKPIFDRQRKESIVPNNNEFLIETFKTREGYHAIFYPFEGRYVHEAMASLI
SYRISLLSPITFSLAYNDYGFELLSDQEIDMQSVFDNNLFTTEYVHHDLQKSLNATEMARRKFRDIAVIAGLVFTGMPGK
PVKTKHLQSGSQLLFEVFRDYEPDNLLLQQAYTETFEHQLEEGRLIQAMERINNQAIVWKQCKKPTPFSFPIITDRLREK
ISSETLQERIKKMTASYMK

Specific function: Unknown

COG id: COG1201

COG function: function code R; Lhr-like helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI38569503, Length=361, Percent_Identity=25.207756232687, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI38569505, Length=361, Percent_Identity=25.207756232687, Blast_Score=77, Evalue=1e-13,
Organism=Escherichia coli, GI1787942, Length=862, Percent_Identity=26.5661252900232, Blast_Score=226, Evalue=5e-60,
Organism=Saccharomyces cerevisiae, GI9755332, Length=499, Percent_Identity=25.6513026052104, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323021, Length=390, Percent_Identity=22.5641025641026, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR013701
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR017170 [H]

Pfam domain/function: PF00270 DEAD; PF08494 DEAD_assoc; PF00271 Helicase_C [H]

EC number: 3.6.1.-

Molecular weight: Translated: 93925; Mature: 93925

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRDELYVLAENWFKSQGWKSFPFQTQTWTAFLQGKNGLLNAPTGSGKTYALWFPVVLDY
CCCCCEEEEEHHHHHCCCCCCCCCCCCHHEEEEECCCCEEECCCCCCCEEEEEHHHHHHH
IKKNPDYKTKHKAGLKAIWITPLRALSVEIKQAAERIITDLDLPLTVGIRSGDTSQSERA
HHCCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
RQKNKMPDLLITTPESLQLLLASKQYEKTFANCGAIIVDEWHELMGTKRGVQMELALSRL
HHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCHHHHHHHHH
KTITPKMRIWGISATIGNLELAQEVLLGHDTEAYKNSVLIKAHINKKIKIESILPEKMET
HHCCCCEEEEEEEEECCCHHHHHHHHHCCCCHHHHCCEEEEEECCCEEEEHHHCCHHHHC
YPWRGHMGLHLIDEVAKIIRKSKTTLIFTNVRSACEIWFQAILEKYPEFAGEMAMHHGSI
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SRETRLWVEDAIRNEELKVVVCTSSLDLGVDFAPVETIIQVGGPKGVARFLQRAGRSGHQ
CHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
PGKESMIYFLATHAMELIEASALKKAVAQTVVEDRMPYLNSWDVLVQYLNTLAVSDGFFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
DEIYEEVKTTFCYQNITKENWNWILNFITNGSQSLQAYDEFKKVEIEADGRYKINSRFIA
HHHHHHHHHHHHHHHCCCCCHHEEEHHHHCCCHHHHHHHHHHEEEEECCCCEEECCEEEE
MHHRMQMGTIVGDAVLNVKFLSGGFIGTIEEWFASKLQRGDVFTFAGRRLELFQIKNMQV
HHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEEECCEEE
LVRKADPKKTARVVSWMGGRMTLSAQMSELLREELYAANTDHLTPELKALKPIFDRQRKE
EEECCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
SIVPNNNEFLIETFKTREGYHAIFYPFEGRYVHEAMASLISYRISLLSPITFSLAYNDYG
CCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
FELLSDQEIDMQSVFDNNLFTTEYVHHDLQKSLNATEMARRKFRDIAVIAGLVFTGMPGK
CEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
PVKTKHLQSGSQLLFEVFRDYEPDNLLLQQAYTETFEHQLEEGRLIQAMERINNQAIVWK
CCCHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEH
QCKKPTPFSFPIITDRLREKISSETLQERIKKMTASYMK
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRDELYVLAENWFKSQGWKSFPFQTQTWTAFLQGKNGLLNAPTGSGKTYALWFPVVLDY
CCCCCEEEEEHHHHHCCCCCCCCCCCCHHEEEEECCCCEEECCCCCCCEEEEEHHHHHHH
IKKNPDYKTKHKAGLKAIWITPLRALSVEIKQAAERIITDLDLPLTVGIRSGDTSQSERA
HHCCCCCCCHHHCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHH
RQKNKMPDLLITTPESLQLLLASKQYEKTFANCGAIIVDEWHELMGTKRGVQMELALSRL
HHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCCCHHHHHHHHH
KTITPKMRIWGISATIGNLELAQEVLLGHDTEAYKNSVLIKAHINKKIKIESILPEKMET
HHCCCCEEEEEEEEECCCHHHHHHHHHCCCCHHHHCCEEEEEECCCEEEEHHHCCHHHHC
YPWRGHMGLHLIDEVAKIIRKSKTTLIFTNVRSACEIWFQAILEKYPEFAGEMAMHHGSI
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SRETRLWVEDAIRNEELKVVVCTSSLDLGVDFAPVETIIQVGGPKGVARFLQRAGRSGHQ
CHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
PGKESMIYFLATHAMELIEASALKKAVAQTVVEDRMPYLNSWDVLVQYLNTLAVSDGFFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
DEIYEEVKTTFCYQNITKENWNWILNFITNGSQSLQAYDEFKKVEIEADGRYKINSRFIA
HHHHHHHHHHHHHHHCCCCCHHEEEHHHHCCCHHHHHHHHHHEEEEECCCCEEECCEEEE
MHHRMQMGTIVGDAVLNVKFLSGGFIGTIEEWFASKLQRGDVFTFAGRRLELFQIKNMQV
HHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHCCCCEEEECCCEEEEEEECCEEE
LVRKADPKKTARVVSWMGGRMTLSAQMSELLREELYAANTDHLTPELKALKPIFDRQRKE
EEECCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
SIVPNNNEFLIETFKTREGYHAIFYPFEGRYVHEAMASLISYRISLLSPITFSLAYNDYG
CCCCCCCCEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCC
FELLSDQEIDMQSVFDNNLFTTEYVHHDLQKSLNATEMARRKFRDIAVIAGLVFTGMPGK
CEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCC
PVKTKHLQSGSQLLFEVFRDYEPDNLLLQQAYTETFEHQLEEGRLIQAMERINNQAIVWK
CCCHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCEEEEH
QCKKPTPFSFPIITDRLREKISSETLQERIKKMTASYMK
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]