Click here to switch to the map view.

The map label for this gene is degT [H]

Identifier: 146299487

GI number: 146299487

Start: 2000753

End: 2001886

Strand: Direct

Name: degT [H]

Synonym: Fjoh_1727

Alternate gene names: 146299487

Gene position: 2000753-2001886 (Clockwise)

Preceding gene: 146299484

Following gene: 146299488

Centisome position: 32.82

GC content: 34.48

Gene sequence:

>1134_bases
ATGAAAAAAATACAAATGGTTGACTTAAAGAGTCAATACGAAAAAATAAAATCTACTGTAGATGCTTCTATTCAAGAAGT
TTTAGACACAAATACTTATATTAACGGGCCATTAGTTCATCAGTTTCAAAAAAATCTTGAAGACTATTTAGGAGCAAAAC
ATGTGATTCCATGTGCAAATGGTACAGATGCTTTGCAGATTGCAATGATGGGATTAGATTTAAAACCAGGTGACGAAGTA
ATTACTGCCGATTTTACTTTTGCAGCAACTGTTGAGGTAATTGCTTTATTACAATTGACTCCGGTTTTAGTTGATGTTGA
TCTGCATAATATGAACATCGATATTGATGCAGTGAAAAAAGCAATCACGCCAAAAACAAAAGCAATTGTTCCAGTTCACT
TATTTGGACGTGCGGCGAATATGGACGCGATTATGGAAATTGCTGCAGAACATAATTTATATGTAATTGAAGATAATGCA
CAGGCAATTGGAGCAGATTATATTTCTAAATCTGGAACAAAATCAAAAGTAGGAACAATTGGCCACGTTGCAGCAACTTC
GTTCTTTCCATCTAAAAACTTAGGATGTTATGGAGACGGAGGAGCAATTTTTACAAATGATGATAAATTAGCACACATCA
TCCGCGGAATTGTAAATCACGGAATGTACGAGCGTTACCACCACGATGTTGTAGGTGTAAATTCTCGTTTAGATAGTATT
CAGGCTGGAGTTTTAAATGCAAAATTGCCGCTTTTAGATGAATATAATGCAGCACGTCGTTTAGCAGCAACAAAATACAA
TGCAGCTTTTGCCGGAAATGCAAAAATTATTACTCCGGATTTTGATGCAAACGAAAATGATCACGTTTTTCATCAATATG
TGTTGAGAATTTTAGATGCTGATAGAAATGCTTTAATGCAGCATTTATTAGACAAAGGAATTCCATGTGCGATTTACTAT
CCAATTCCATTGCATTCTCAAAAAGCATACTTAGATCCTCGTTATAAAGAAGAGCAGTTCCCGGTAACTGATCAATTGGT
ACAGGAAGTAATTGCTTTACCAATGCATACTGAGCTTGACGACGAACAAATTAAATTTATTACAGATTCTGTTTTAGAAT
TTTTAAATAAATAA

Upstream 100 bases:

>100_bases
ACTATTTTCATTGGTTTGAAGCTATTAATAACTATTTTTGTTCCTCCTTTTAGAGATTTCTGTCTAAAATAGAGTCTTTA
ATTTTAAACATTATTCAAAA

Downstream 100 bases:

>100_bases
TAAAAGCCAAAATAACCACAAAACAACCCAATAAATGAAAGTATTAGTAACAGGAGGATTAGGATTTATCGGTTCTCACA
CTGTAGTCGAATTGCAAAAC

Product: DegT/DnrJ/EryC1/StrS aminotransferase

Products: TDP-D-fucosamine; 2-oxoglutarate [C]

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKKIQMVDLKSQYEKIKSTVDASIQEVLDTNTYINGPLVHQFQKNLEDYLGAKHVIPCANGTDALQIAMMGLDLKPGDEV
ITADFTFAATVEVIALLQLTPVLVDVDLHNMNIDIDAVKKAITPKTKAIVPVHLFGRAANMDAIMEIAAEHNLYVIEDNA
QAIGADYISKSGTKSKVGTIGHVAATSFFPSKNLGCYGDGGAIFTNDDKLAHIIRGIVNHGMYERYHHDVVGVNSRLDSI
QAGVLNAKLPLLDEYNAARRLAATKYNAAFAGNAKIITPDFDANENDHVFHQYVLRILDADRNALMQHLLDKGIPCAIYY
PIPLHSQKAYLDPRYKEEQFPVTDQLVQEVIALPMHTELDDEQIKFITDSVLEFLNK

Sequences:

>Translated_377_residues
MKKIQMVDLKSQYEKIKSTVDASIQEVLDTNTYINGPLVHQFQKNLEDYLGAKHVIPCANGTDALQIAMMGLDLKPGDEV
ITADFTFAATVEVIALLQLTPVLVDVDLHNMNIDIDAVKKAITPKTKAIVPVHLFGRAANMDAIMEIAAEHNLYVIEDNA
QAIGADYISKSGTKSKVGTIGHVAATSFFPSKNLGCYGDGGAIFTNDDKLAHIIRGIVNHGMYERYHHDVVGVNSRLDSI
QAGVLNAKLPLLDEYNAARRLAATKYNAAFAGNAKIITPDFDANENDHVFHQYVLRILDADRNALMQHLLDKGIPCAIYY
PIPLHSQKAYLDPRYKEEQFPVTDQLVQEVIALPMHTELDDEQIKFITDSVLEFLNK
>Mature_377_residues
MKKIQMVDLKSQYEKIKSTVDASIQEVLDTNTYINGPLVHQFQKNLEDYLGAKHVIPCANGTDALQIAMMGLDLKPGDEV
ITADFTFAATVEVIALLQLTPVLVDVDLHNMNIDIDAVKKAITPKTKAIVPVHLFGRAANMDAIMEIAAEHNLYVIEDNA
QAIGADYISKSGTKSKVGTIGHVAATSFFPSKNLGCYGDGGAIFTNDDKLAHIIRGIVNHGMYERYHHDVVGVNSRLDSI
QAGVLNAKLPLLDEYNAARRLAATKYNAAFAGNAKIITPDFDANENDHVFHQYVLRILDADRNALMQHLLDKGIPCAIYY
PIPLHSQKAYLDPRYKEEQFPVTDQLVQEVIALPMHTELDDEQIKFITDSVLEFLNK

Specific function: This membrane protein may function as a sensor protein and may transfer the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of the genes [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI2367285, Length=359, Percent_Identity=32.5905292479109, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI145693159, Length=355, Percent_Identity=30.4225352112676, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 41756; Mature: 41756

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIQMVDLKSQYEKIKSTVDASIQEVLDTNTYINGPLVHQFQKNLEDYLGAKHVIPCAN
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCC
GTDALQIAMMGLDLKPGDEVITADFTFAATVEVIALLQLTPVLVDVDLHNMNIDIDAVKK
CCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHH
AITPKTKAIVPVHLFGRAANMDAIMEIAAEHNLYVIEDNAQAIGADYISKSGTKSKVGTI
HCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHCHHHHHCCCCCCCCCCH
GHVAATSFFPSKNLGCYGDGGAIFTNDDKLAHIIRGIVNHGMYERYHHDVVGVNSRLDSI
HHHHHHCCCCCCCCCEEECCCEEEECCHHHHHHHHHHHHCCHHHHHHCCCEECCHHHHHH
QAGVLNAKLPLLDEYNAARRLAATKYNAAFAGNAKIITPDFDANENDHVFHQYVLRILDA
HHHHHCCCCCCHHCHHHHHHHHHHHCCEEEECCCEEECCCCCCCCCCHHHHHHHHHHHCC
DRNALMQHLLDKGIPCAIYYPIPLHSQKAYLDPRYKEEQFPVTDQLVQEVIALPMHTELD
CHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
DEQIKFITDSVLEFLNK
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIQMVDLKSQYEKIKSTVDASIQEVLDTNTYINGPLVHQFQKNLEDYLGAKHVIPCAN
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCC
GTDALQIAMMGLDLKPGDEVITADFTFAATVEVIALLQLTPVLVDVDLHNMNIDIDAVKK
CCCCEEEEEECCCCCCCCCEEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHH
AITPKTKAIVPVHLFGRAANMDAIMEIAAEHNLYVIEDNAQAIGADYISKSGTKSKVGTI
HCCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCHHCHHHHHCCCCCCCCCCH
GHVAATSFFPSKNLGCYGDGGAIFTNDDKLAHIIRGIVNHGMYERYHHDVVGVNSRLDSI
HHHHHHCCCCCCCCCEEECCCEEEECCHHHHHHHHHHHHCCHHHHHHCCCEECCHHHHHH
QAGVLNAKLPLLDEYNAARRLAATKYNAAFAGNAKIITPDFDANENDHVFHQYVLRILDA
HHHHHCCCCCCHHCHHHHHHHHHHHCCEEEECCCEEECCCCCCCCCCHHHHHHHHHHHCC
DRNALMQHLLDKGIPCAIYYPIPLHSQKAYLDPRYKEEQFPVTDQLVQEVIALPMHTELD
CHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
DEQIKFITDSVLEFLNK
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose; L-glutamate [C]

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-D-fucosamine + 2-oxoglutarate [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104607 [H]