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The map label for this gene is galE [H]

Identifier: 146299488

GI number: 146299488

Start: 2001921

End: 2002937

Strand: Direct

Name: galE [H]

Synonym: Fjoh_1728

Alternate gene names: 146299488

Gene position: 2001921-2002937 (Clockwise)

Preceding gene: 146299487

Following gene: 146299489

Centisome position: 32.84

GC content: 37.36

Gene sequence:

>1017_bases
ATGAAAGTATTAGTAACAGGAGGATTAGGATTTATCGGTTCTCACACTGTAGTCGAATTGCAAAACGAAGGCTATGAGGT
AGTGATCATTGATAATCTTTCCAATTCTTCAGAAGATGTTTTAAAAGGGATTACCGCGATTACAGGAAAAACGCCTTTAT
TCGAAAAAATTGATTTAAGAGAAAAAAGCGCCGTTCGGGATTTCTTTAAAAAACACAATGATGTTACTGGTGTGATTCAT
TTTGCAGCTTCAAAAGCAGTTGGTGAAAGTGTTGAACAGCCTTTGTTGTATTATGAAAACAACATTAGCAGTTTAGTTTA
TCTTTTACAGGAATTACAGCAAAAACCTGAAGCAAGTTTTATTTTCAGTTCTTCTTGTACAGTTTACGGTCAGGCCGAAA
AAATGCCAATTACAGAAGATGCTCCGGTACAAACTGCAATGTCTCCTTACGGAAATACCAAACAGATGGGAGAAGAAATT
ATTACCGATACAGCAAAGGTTACTAATATCAGCGCGATTTTATTACGTTATTTTAATCCGGTTGGAGCACATGAAACAGC
TGAAATTGGAGAGCTTCCGTTGGGAGTTCCTCAAAATTTAGTTCCGTTTATCACGCAGACTGGAGTTGGTTTGCGCCAGG
AATTATCGGTTTTTGGAAATGATTATCCAACACCGGACGGTACTGCGGTTCGTGATTATATTCATGTTGTCGATTTAGCA
AAAGCGCACGTAATTGCTTTACAACGTTTGTTTAATAAAAAGAATGCAGCAAAAGTAGAAACCTTCAATTTAGGAACAGG
AAAAGGAAGTTCTGTTTTAGAAGTCATTCATAGCTTTGAAAAAGTCAGCGGTAAAAAACTGCCTTACAAGATGATGCCTC
GTCGTGAAGGTGATATTACTGAAGCTTATGCAAATACAGATAAGGCAAATAATGTCTTAGGATGGAAGGCAGAACTTAGT
TTAGACGAAGCAATGGCAAGCGCCTGGAAATGGGAACAAAAAGTGAGGAATAAATAA

Upstream 100 bases:

>100_bases
ACTGAGCTTGACGACGAACAAATTAAATTTATTACAGATTCTGTTTTAGAATTTTTAAATAAATAATAAAAGCCAAAATA
ACCACAAAACAACCCAATAA

Downstream 100 bases:

>100_bases
ATTCTTTATTAGTTAAAATTATAAAATTTTAAGATCCCAAATTATAGCAGTATAGTTTGGGATTTTTTTTTAACGTATTA
ATTATCATGAAACAAAGCTT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKVLVTGGLGFIGSHTVVELQNEGYEVVIIDNLSNSSEDVLKGITAITGKTPLFEKIDLREKSAVRDFFKKHNDVTGVIH
FAASKAVGESVEQPLLYYENNISSLVYLLQELQQKPEASFIFSSSCTVYGQAEKMPITEDAPVQTAMSPYGNTKQMGEEI
ITDTAKVTNISAILLRYFNPVGAHETAEIGELPLGVPQNLVPFITQTGVGLRQELSVFGNDYPTPDGTAVRDYIHVVDLA
KAHVIALQRLFNKKNAAKVETFNLGTGKGSSVLEVIHSFEKVSGKKLPYKMMPRREGDITEAYANTDKANNVLGWKAELS
LDEAMASAWKWEQKVRNK

Sequences:

>Translated_338_residues
MKVLVTGGLGFIGSHTVVELQNEGYEVVIIDNLSNSSEDVLKGITAITGKTPLFEKIDLREKSAVRDFFKKHNDVTGVIH
FAASKAVGESVEQPLLYYENNISSLVYLLQELQQKPEASFIFSSSCTVYGQAEKMPITEDAPVQTAMSPYGNTKQMGEEI
ITDTAKVTNISAILLRYFNPVGAHETAEIGELPLGVPQNLVPFITQTGVGLRQELSVFGNDYPTPDGTAVRDYIHVVDLA
KAHVIALQRLFNKKNAAKVETFNLGTGKGSSVLEVIHSFEKVSGKKLPYKMMPRREGDITEAYANTDKANNVLGWKAELS
LDEAMASAWKWEQKVRNK
>Mature_338_residues
MKVLVTGGLGFIGSHTVVELQNEGYEVVIIDNLSNSSEDVLKGITAITGKTPLFEKIDLREKSAVRDFFKKHNDVTGVIH
FAASKAVGESVEQPLLYYENNISSLVYLLQELQQKPEASFIFSSSCTVYGQAEKMPITEDAPVQTAMSPYGNTKQMGEEI
ITDTAKVTNISAILLRYFNPVGAHETAEIGELPLGVPQNLVPFITQTGVGLRQELSVFGNDYPTPDGTAVRDYIHVVDLA
KAHVIALQRLFNKKNAAKVETFNLGTGKGSSVLEVIHSFEKVSGKKLPYKMMPRREGDITEAYANTDKANNVLGWKAELS
LDEAMASAWKWEQKVRNK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=46.7647058823529, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=46.7647058823529, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=46.7647058823529, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI7657641, Length=278, Percent_Identity=24.1007194244604, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=48.0597014925373, Blast_Score=332, Evalue=2e-92,
Organism=Escherichia coli, GI48994969, Length=355, Percent_Identity=23.943661971831, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788353, Length=359, Percent_Identity=23.3983286908078, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=342, Percent_Identity=45.3216374269006, Blast_Score=297, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=44.7674418604651, Blast_Score=294, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=47.1810089020772, Blast_Score=305, Evalue=5e-84,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=47.093023255814, Blast_Score=317, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37214; Mature: 37214

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGGLGFIGSHTVVELQNEGYEVVIIDNLSNSSEDVLKGITAITGKTPLFEKIDLR
CEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHCCH
EKSAVRDFFKKHNDVTGVIHFAASKAVGESVEQPLLYYENNISSLVYLLQELQQKPEASF
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCEE
IFSSSCTVYGQAEKMPITEDAPVQTAMSPYGNTKQMGEEIITDTAKVTNISAILLRYFNP
EEECCCEEEECCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCC
VGAHETAEIGELPLGVPQNLVPFITQTGVGLRQELSVFGNDYPTPDGTAVRDYIHVVDLA
CCCCCCHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
KAHVIALQRLFNKKNAAKVETFNLGTGKGSSVLEVIHSFEKVSGKKLPYKMMPRREGDIT
HHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHH
EAYANTDKANNVLGWKAELSLDEAMASAWKWEQKVRNK
HHHCCCCCCCCEECEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVLVTGGLGFIGSHTVVELQNEGYEVVIIDNLSNSSEDVLKGITAITGKTPLFEKIDLR
CEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHCCH
EKSAVRDFFKKHNDVTGVIHFAASKAVGESVEQPLLYYENNISSLVYLLQELQQKPEASF
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCCCCEE
IFSSSCTVYGQAEKMPITEDAPVQTAMSPYGNTKQMGEEIITDTAKVTNISAILLRYFNP
EEECCCEEEECCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCC
VGAHETAEIGELPLGVPQNLVPFITQTGVGLRQELSVFGNDYPTPDGTAVRDYIHVVDLA
CCCCCCHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
KAHVIALQRLFNKKNAAKVETFNLGTGKGSSVLEVIHSFEKVSGKKLPYKMMPRREGDIT
HHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCHH
EAYANTDKANNVLGWKAELSLDEAMASAWKWEQKVRNK
HHHCCCCCCCCEECEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]