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The map label for this gene is clpX [H]

Identifier: 146299463

GI number: 146299463

Start: 1973499

End: 1974731

Strand: Direct

Name: clpX [H]

Synonym: Fjoh_1703

Alternate gene names: 146299463

Gene position: 1973499-1974731 (Clockwise)

Preceding gene: 146299462

Following gene: 146299464

Centisome position: 32.37

GC content: 34.23

Gene sequence:

>1233_bases
ATGGCAAAAGTAGTATTAGAATGTTCGTTTTGTGGAAGAAAAAAGCCAGAAACTAATTTATTAATTGCCGGTATAAATGC
ACACATTTGTGATAAGTGTATTGAGCAGGCACACGGAATTGTTTTAGAAGAATTAAAATCAAGCGGAAGTGCAAAACTTG
TAGGTGATTTAATTCTAAAAAAGCCAAAAGAAATCAGAGCTTTTCTAGACCAATACGTTATTGGTCAGGATCAGACAAAA
AAAGTAATGTCAGTAGCTGTTTACAATCACTACAAACGTTTAATGCAGCAGCAATTAGACGACGAAGTAGAGATTGAAAA
AAGTAACATTATTATGGTAGGACAAACCGGAACAGGAAAAACATTGGTTGCAAAAACTATTGCAAAAATGTTAGATGTTC
CTTTGGCTATTGTAGATGCAACTGTACTTACAGAAGCAGGTTACGTAGGAGAAGATGTTGAAAGTATTTTAACCCGACTT
TTACAAGCTGCAGATTATGATGTAACCAAGGCAGAAAGAGGAATCGTATTTATTGACGAAATAGATAAAATCGCCCGCAA
AAGCGACAATCCGTCTATAACACGTGACGTTTCTGGAGAAGGTGTTCAGCAAGCTTTGTTAAAATTATTAGAAGGAACAG
TTGTTAACGTACCGCCAAAAGGAGGACGTAAACACCCAGACCAGAAATTTGTTGAAGTAAATACTCAAAATATCCTGTTT
ATTGCAGGAGGAGCATTTGATGGAGTAGAACGTATTATTTCAAAACGTTTAAACCGTCAGGCAGTTGGATATTCGACTTC
AAAAAATGCAGACAATATCGATAAAGACAATTTATTGCAGTATATCATTCCAAAAGACATTAAAGATTTTGGATTAATTC
CCGAGATAATTGGCCGTTTACCAGTTTTAACGCACATGGATCCTTTAGATAAGGAAACCTTACGTGCGATTTTAACACAG
CCGAAAAATGCATTAGTAAAACAATATCAGAAGTTATTCTTAATGGATGAAGTTGAATTTACTATTACAGATGAAGCTTT
AGATTTTATTGTAGATAAAGCTTTAGAATATAAATTAGGAGCCCGTGGATTACGTTCGCTTTGTGAAGCTATTTTAACAG
ATGCGATGTATGAATTACCAAGTTCTGATGATAAAATTTTATCAATCGATAAAGATTATGCAGAACATACTTTAAGTAAA
AACTTATTGAAGCGTATGGAAATTGCTTCGTAA

Upstream 100 bases:

>100_bases
AAAAAATAAATATTAAGCTGTAAAGGTGTTAAGTTTTAAAGTTTTAAAATCAAAAAGCTTAGAAACTTAGTATCTTTGCA
GCTTAGTAACTAAATATAGA

Downstream 100 bases:

>100_bases
AATCTCTAAATAACTTTGTCGAAATTTTAAACTTTGACAAAATTTCACTTTTAAACCTGTTCAATTTTTGAACAGGTTTT
TTTATACTTTTAAAGTAAGA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAKVVLECSFCGRKKPETNLLIAGINAHICDKCIEQAHGIVLEELKSSGSAKLVGDLILKKPKEIRAFLDQYVIGQDQTK
KVMSVAVYNHYKRLMQQQLDDEVEIEKSNIIMVGQTGTGKTLVAKTIAKMLDVPLAIVDATVLTEAGYVGEDVESILTRL
LQAADYDVTKAERGIVFIDEIDKIARKSDNPSITRDVSGEGVQQALLKLLEGTVVNVPPKGGRKHPDQKFVEVNTQNILF
IAGGAFDGVERIISKRLNRQAVGYSTSKNADNIDKDNLLQYIIPKDIKDFGLIPEIIGRLPVLTHMDPLDKETLRAILTQ
PKNALVKQYQKLFLMDEVEFTITDEALDFIVDKALEYKLGARGLRSLCEAILTDAMYELPSSDDKILSIDKDYAEHTLSK
NLLKRMEIAS

Sequences:

>Translated_410_residues
MAKVVLECSFCGRKKPETNLLIAGINAHICDKCIEQAHGIVLEELKSSGSAKLVGDLILKKPKEIRAFLDQYVIGQDQTK
KVMSVAVYNHYKRLMQQQLDDEVEIEKSNIIMVGQTGTGKTLVAKTIAKMLDVPLAIVDATVLTEAGYVGEDVESILTRL
LQAADYDVTKAERGIVFIDEIDKIARKSDNPSITRDVSGEGVQQALLKLLEGTVVNVPPKGGRKHPDQKFVEVNTQNILF
IAGGAFDGVERIISKRLNRQAVGYSTSKNADNIDKDNLLQYIIPKDIKDFGLIPEIIGRLPVLTHMDPLDKETLRAILTQ
PKNALVKQYQKLFLMDEVEFTITDEALDFIVDKALEYKLGARGLRSLCEAILTDAMYELPSSDDKILSIDKDYAEHTLSK
NLLKRMEIAS
>Mature_409_residues
AKVVLECSFCGRKKPETNLLIAGINAHICDKCIEQAHGIVLEELKSSGSAKLVGDLILKKPKEIRAFLDQYVIGQDQTKK
VMSVAVYNHYKRLMQQQLDDEVEIEKSNIIMVGQTGTGKTLVAKTIAKMLDVPLAIVDATVLTEAGYVGEDVESILTRLL
QAADYDVTKAERGIVFIDEIDKIARKSDNPSITRDVSGEGVQQALLKLLEGTVVNVPPKGGRKHPDQKFVEVNTQNILFI
AGGAFDGVERIISKRLNRQAVGYSTSKNADNIDKDNLLQYIIPKDIKDFGLIPEIIGRLPVLTHMDPLDKETLRAILTQP
KNALVKQYQKLFLMDEVEFTITDEALDFIVDKALEYKLGARGLRSLCEAILTDAMYELPSSDDKILSIDKDYAEHTLSKN
LLKRMEIAS

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=320, Percent_Identity=49.6875, Blast_Score=306, Evalue=2e-83,
Organism=Escherichia coli, GI1786642, Length=383, Percent_Identity=56.3968668407311, Blast_Score=432, Evalue=1e-122,
Organism=Escherichia coli, GI1790366, Length=105, Percent_Identity=42.8571428571429, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982905, Length=307, Percent_Identity=43.9739413680782, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71982908, Length=307, Percent_Identity=43.9739413680782, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=413, Percent_Identity=36.319612590799, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=251, Percent_Identity=40.2390438247012, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=435, Percent_Identity=37.0114942528736, Blast_Score=256, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24648291, Length=310, Percent_Identity=48.0645161290323, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24648289, Length=310, Percent_Identity=48.0645161290323, Blast_Score=285, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 45555; Mature: 45424

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00675 SIGMA54_INTERACT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKVVLECSFCGRKKPETNLLIAGINAHICDKCIEQAHGIVLEELKSSGSAKLVGDLILK
CCEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHC
KPKEIRAFLDQYVIGQDQTKKVMSVAVYNHYKRLMQQQLDDEVEIEKSNIIMVGQTGTGK
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCH
TLVAKTIAKMLDVPLAIVDATVLTEAGYVGEDVESILTRLLQAADYDVTKAERGIVFIDE
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEHHH
IDKIARKSDNPSITRDVSGEGVQQALLKLLEGTVVNVPPKGGRKHPDQKFVEVNTQNILF
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEECCCEEEE
IAGGAFDGVERIISKRLNRQAVGYSTSKNADNIDKDNLLQYIIPKDIKDFGLIPEIIGRL
EECCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHCCCHHHHHCCC
PVLTHMDPLDKETLRAILTQPKNALVKQYQKLFLMDEVEFTITDEALDFIVDKALEYKLG
CCHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHH
ARGLRSLCEAILTDAMYELPSSDDKILSIDKDYAEHTLSKNLLKRMEIAS
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKVVLECSFCGRKKPETNLLIAGINAHICDKCIEQAHGIVLEELKSSGSAKLVGDLILK
CEEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHC
KPKEIRAFLDQYVIGQDQTKKVMSVAVYNHYKRLMQQQLDDEVEIEKSNIIMVGQTGTGK
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCCH
TLVAKTIAKMLDVPLAIVDATVLTEAGYVGEDVESILTRLLQAADYDVTKAERGIVFIDE
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHCCCEEEHHH
IDKIARKSDNPSITRDVSGEGVQQALLKLLEGTVVNVPPKGGRKHPDQKFVEVNTQNILF
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCCCEEEECCCEEEE
IAGGAFDGVERIISKRLNRQAVGYSTSKNADNIDKDNLLQYIIPKDIKDFGLIPEIIGRL
EECCCHHHHHHHHHHHHCHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHCCCHHHHHCCC
PVLTHMDPLDKETLRAILTQPKNALVKQYQKLFLMDEVEFTITDEALDFIVDKALEYKLG
CCHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHH
ARGLRSLCEAILTDAMYELPSSDDKILSIDKDYAEHTLSKNLLKRMEIAS
HHHHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA