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The map label for this gene is tolC [C]

Identifier: 146299431

GI number: 146299431

Start: 1940071

End: 1941456

Strand: Direct

Name: tolC [C]

Synonym: Fjoh_1671

Alternate gene names: 146299431

Gene position: 1940071-1941456 (Clockwise)

Preceding gene: 146299430

Following gene: 146299432

Centisome position: 31.82

GC content: 33.41

Gene sequence:

>1386_bases
ATGAAAATAAATAAATATAATAGTCTTGTTTTTGCCATGCTGTTCGGTTTTGGATTATCGGGCCAGGCACAAACAAAACA
ATGGACTTTAGAAGAATGTGTGAGATACGCATTAGATAACAATATCACGATTAAGCTGTCTGAACTTGATGTAAAAACAG
CAGATATTGATAAAAGAGGTGCTTTGGGAAGTTATCTGCCAACAGTAAACGGAAATGCTTCACACTCTTGGAATATTGGT
TTGAACGTTAACCCGGTTACCAACATTGCAACTACGCAGACTACTCAGTATTCTTCATTAGGAGTAAATGCCAATGTTGA
TATTTACAAAGGTCTGCAAAATCAAAATGCATATAGAAGAGCTTCACTTGCTATTGTAGCATCAAAATATCAATTGTTGA
AAATGCAGGAAGATATTTCTCTGAATGTAGCCAACGCTTTCCTGCAGATTTTATCTAACAAAGAAAATTTAAAAGTAAGA
ATAGAACAATTAGCTATTGACGAAAAACGTCTTGCACGTTCTGAGGAAATGGTTAATGCCGGAACAATTCCCCGTGGTGA
TTTATTTGATTTAAAAGCTACTGTTGCAACAGATAAGCAAAATATCACAGTTTCTGAAAACAATTTACTGATTTCAAAAT
TGAGTTTAGCGCAGCTTTTACAATTAAAAGAGTTTGCTGATTTTGATGTAGTAGATGATACAAATGCCAAAGATGAAAAC
AATATCATGGCACAATCGCCAATTGATATCTACAATAAAGCAAAAGAAATTAGAACGGAATTAAAATTAGCACAGACTAA
TTTGGAAATTGCCGAGAAAAATGTTTCAATTGCAAAAGGAGCTTATCAGCCAACTTTAAGAGGATTCTATTCTTTCAGCA
CAAGTGCAAGTTACAGTGACCGACTAATTGGAGCTGATGCAGCAGGAAATCCAATTTACGTTGGTCCAGATCCCGTTTTA
ACTCAGTTTAGTGATAATAAAGGACACAATTTCGGATTTCAGTTAAGTGTGCCAATCTTTAATGGTTTCTCTGTTAGAAA
CAATGTTGAAAGAAACAAAGTAAGTTTGGAAAAATCTAAAATAGATTTGGAACAAAAAAGCTTAGATTTGCAGCGTAACG
TTTATACTGCTTTTACAGATGCAAAAGGTGCTTTAAATACCTATGAATCTGCAACAGTTTCTTTAGAAGCAAGACAGCAG
GCCTATAATTATGCTAAAGAAAAGTACGATGTTGGTTTAATGAATTCATTTGATTTTACACAAGCACAAACTTTGCTTAC
AAATGCACAATCAGACGTTATTAGAACGAAATACGATTACATGTTTAAAATTAAAATACTTGAATTCTATTTCGGAATTC
CAATTGTTCCAGTTATTACAAAATAA

Upstream 100 bases:

>100_bases
CGATGAAAAAGAGAAAAAATAATTGAAATCGTAAAGAGTTTTTTTGGTTTTAAAAAATGTTAAATTTGCGCAGCATCGAC
TGCGCCATCAATCAAAATAT

Downstream 100 bases:

>100_bases
TTTATTATGTCAAAAAAAATAGTTTACTTCTCAGTTGGCGGGGCATTAGTTCTAATTGCATTATTAGTAAGTCTTTCTAA
GGCAGGAGTAATAGGAAATA

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Outer Membrane Transport/Efflux Protein; Outer Membrane Macrolide Efflux Protein; Outer Membrane Protein; Outer Membrane Protein lC; HlyD Family Secretion Protein; Efflux System Outer Membrane Protein; LC Family Type I Secretion Outer Membrane Protein; Outer Membrane Lipoprotein; Type I Secretion Outer Membrane Protein; Outer Membrane Channel Protein; Outer Membrane Protein-Like Protein

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MKINKYNSLVFAMLFGFGLSGQAQTKQWTLEECVRYALDNNITIKLSELDVKTADIDKRGALGSYLPTVNGNASHSWNIG
LNVNPVTNIATTQTTQYSSLGVNANVDIYKGLQNQNAYRRASLAIVASKYQLLKMQEDISLNVANAFLQILSNKENLKVR
IEQLAIDEKRLARSEEMVNAGTIPRGDLFDLKATVATDKQNITVSENNLLISKLSLAQLLQLKEFADFDVVDDTNAKDEN
NIMAQSPIDIYNKAKEIRTELKLAQTNLEIAEKNVSIAKGAYQPTLRGFYSFSTSASYSDRLIGADAAGNPIYVGPDPVL
TQFSDNKGHNFGFQLSVPIFNGFSVRNNVERNKVSLEKSKIDLEQKSLDLQRNVYTAFTDAKGALNTYESATVSLEARQQ
AYNYAKEKYDVGLMNSFDFTQAQTLLTNAQSDVIRTKYDYMFKIKILEFYFGIPIVPVITK

Sequences:

>Translated_461_residues
MKINKYNSLVFAMLFGFGLSGQAQTKQWTLEECVRYALDNNITIKLSELDVKTADIDKRGALGSYLPTVNGNASHSWNIG
LNVNPVTNIATTQTTQYSSLGVNANVDIYKGLQNQNAYRRASLAIVASKYQLLKMQEDISLNVANAFLQILSNKENLKVR
IEQLAIDEKRLARSEEMVNAGTIPRGDLFDLKATVATDKQNITVSENNLLISKLSLAQLLQLKEFADFDVVDDTNAKDEN
NIMAQSPIDIYNKAKEIRTELKLAQTNLEIAEKNVSIAKGAYQPTLRGFYSFSTSASYSDRLIGADAAGNPIYVGPDPVL
TQFSDNKGHNFGFQLSVPIFNGFSVRNNVERNKVSLEKSKIDLEQKSLDLQRNVYTAFTDAKGALNTYESATVSLEARQQ
AYNYAKEKYDVGLMNSFDFTQAQTLLTNAQSDVIRTKYDYMFKIKILEFYFGIPIVPVITK
>Mature_461_residues
MKINKYNSLVFAMLFGFGLSGQAQTKQWTLEECVRYALDNNITIKLSELDVKTADIDKRGALGSYLPTVNGNASHSWNIG
LNVNPVTNIATTQTTQYSSLGVNANVDIYKGLQNQNAYRRASLAIVASKYQLLKMQEDISLNVANAFLQILSNKENLKVR
IEQLAIDEKRLARSEEMVNAGTIPRGDLFDLKATVATDKQNITVSENNLLISKLSLAQLLQLKEFADFDVVDDTNAKDEN
NIMAQSPIDIYNKAKEIRTELKLAQTNLEIAEKNVSIAKGAYQPTLRGFYSFSTSASYSDRLIGADAAGNPIYVGPDPVL
TQFSDNKGHNFGFQLSVPIFNGFSVRNNVERNKVSLEKSKIDLEQKSLDLQRNVYTAFTDAKGALNTYESATVSLEARQQ
AYNYAKEKYDVGLMNSFDFTQAQTLLTNAQSDVIRTKYDYMFKIKILEFYFGIPIVPVITK

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51468; Mature: 51468

Theoretical pI: Translated: 7.46; Mature: 7.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINKYNSLVFAMLFGFGLSGQAQTKQWTLEECVRYALDNNITIKLSELDVKTADIDKRG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECEEEECCCCCCC
ALGSYLPTVNGNASHSWNIGLNVNPVTNIATTQTTQYSSLGVNANVDIYKGLQNQNAYRR
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCHHCCCCCCCCHHCCCCCCCCCHHH
ASLAIVASKYQLLKMQEDISLNVANAFLQILSNKENLKVRIEQLAIDEKRLARSEEMVNA
HEEEEEEHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCEEEEEHHHCCHHHHHHHHHHHCC
GTIPRGDLFDLKATVATDKQNITVSENNLLISKLSLAQLLQLKEFADFDVVDDTNAKDEN
CCCCCCCCEEEEEEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NIMAQSPIDIYNKAKEIRTELKLAQTNLEIAEKNVSIAKGAYQPTLRGFYSFSTSASYSD
CEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCHHHHHHEECCCCCCCCC
RLIGADAAGNPIYVGPDPVLTQFSDNKGHNFGFQLSVPIFNGFSVRNNVERNKVSLEKSK
CEEECCCCCCCEEECCCCCEECCCCCCCCCCEEEEEEEEECCEECCCCCCHHHEEHHHHH
IDLEQKSLDLQRNVYTAFTDAKGALNTYESATVSLEARQQAYNYAKEKYDVGLMNSFDFT
CCHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCHH
QAQTLLTNAQSDVIRTKYDYMFKIKILEFYFGIPIVPVITK
HHHHHHHCCHHHHHHCCCCEEEEEEEEHHHHCCCCEEEECC
>Mature Secondary Structure
MKINKYNSLVFAMLFGFGLSGQAQTKQWTLEECVRYALDNNITIKLSELDVKTADIDKRG
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECEEEECCCCCCC
ALGSYLPTVNGNASHSWNIGLNVNPVTNIATTQTTQYSSLGVNANVDIYKGLQNQNAYRR
CCCCCCCCCCCCCCCEEEEEEECCCCCCEEECCCCCHHCCCCCCCCHHCCCCCCCCCHHH
ASLAIVASKYQLLKMQEDISLNVANAFLQILSNKENLKVRIEQLAIDEKRLARSEEMVNA
HEEEEEEHHHHHHHHHCCCEEHHHHHHHHHHCCCCCCEEEEEHHHCCHHHHHHHHHHHCC
GTIPRGDLFDLKATVATDKQNITVSENNLLISKLSLAQLLQLKEFADFDVVDDTNAKDEN
CCCCCCCCEEEEEEEECCCCCEEEECCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NIMAQSPIDIYNKAKEIRTELKLAQTNLEIAEKNVSIAKGAYQPTLRGFYSFSTSASYSD
CEEECCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCCCCHHHHHHEECCCCCCCCC
RLIGADAAGNPIYVGPDPVLTQFSDNKGHNFGFQLSVPIFNGFSVRNNVERNKVSLEKSK
CEEECCCCCCCEEECCCCCEECCCCCCCCCCEEEEEEEEECCEECCCCCCHHHEEHHHHH
IDLEQKSLDLQRNVYTAFTDAKGALNTYESATVSLEARQQAYNYAKEKYDVGLMNSFDFT
CCHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCHH
QAQTLLTNAQSDVIRTKYDYMFKIKILEFYFGIPIVPVITK
HHHHHHHCCHHHHHHCCCCEEEEEEEEHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA