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The map label for this gene is nadR [C]

Identifier: 146299346

GI number: 146299346

Start: 1836216

End: 1838330

Strand: Direct

Name: nadR [C]

Synonym: Fjoh_1586

Alternate gene names: 146299346

Gene position: 1836216-1838330 (Clockwise)

Preceding gene: 146299345

Following gene: 146299347

Centisome position: 30.12

GC content: 31.35

Gene sequence:

>2115_bases
ATGGAGAAAAATCTTAGACAGCAAAAAACAAATATCATAAAAATTGCTTTGTTTGGCCCTGAAAGTACAGGTAAAACTAC
ATTAGCAAAACAACTCGCAGACCACTACAAAACAGAATGGGTTCCAGAGTTTGCACGCGATTATCTGCAGGAAAGATGGG
AAGAAAATCAGCATATATGTACTGTTGATGATATGATGCCTATTGCTTACGGGCAAGTTTTATTAGAGAATGAGAAGCTT
ACCGAGGCGAATAAATATTTGTTTTGCGATACTAATTTAATGGTAACTAAAGTCTTCTCTGAAGTGTATTACGGTTTTTG
TGATCCACTTTTAAATGAAGCTGCCTTAGAACATGATTACGATTTGTTTTTCCTCACGGATATTGATGTTCCATGGGAAA
AAGATGACATTAGAGATACTCCGGAAGGAAGAGAAACCGTTTTTTCTGTATTCAAACAAACTTTAATTGATAATAAAAAG
CCTTTTATAACCTTATCAGGTAATAAAGAAAGTCGTTTGGCAAAAGCTATAATGATTATAGATGCTTTAGGTGCTTTAAA
AGAAAAAGGATTTTCTTCTCAGGATTTTGTTGAAATTTATAATCACGGAATTCCTTTCGAAAATATTTTAAAACAGCTGG
ATATATTCAAAAACGGAATAGCAAAGAGCAGCTTGATTCGTCCAGCGACAATCAATAATGGCATTCTTAGTTTATCAGAA
GTTGATTTTAAAGAAAAAGCTTCTTTTTTTGATAAACATAAAGAAGAATTTAAAATTAAAAAATTTGTTCCGGCTTCTGG
TGCTGCTACCAGAATGTATAAGTTTTTAACGGCCTTTTTAAATGATTTTGATATTGAAAAAGAAACCATAAATGCTTATA
TCAATAGGAAAAAAGATAAAGAACTAGCCATTTTTATTATTGGAATGGATAAGTTTCCTTTTTTTGATGATGTTGACAAA
AAACTGAGAGAACTTTATCCAGATTTTGAAAACCTGGAAAGAGATTATAAAAACTATTATTTTATAAAACTGTTATTATC
TCCTGAACATTTTAACTCGGCAAACAAGCCAAAAGCAGTTTTACCATTTCATTTATATAAAACTCATATAGCAACACCTA
TAGAAGAACATTTAAATGAATGTGTGCATTATGCAACAGCAAAGCGTATTTCGAATTTACATTTTACAGTTTCAGAAATA
CATCAGAATTTGTTTGAAAAAACAGTCGATGCAGTTAAAAACAAAGTAGAGGAACATTCTAATGTTAAAATTAACATTAG
ATATTCTTATCAAAATAAAGGTACAGATTCAATTAATGTAGATGTAAATAATAAACTGGTGAGAAGTTCAAATGGAAGTC
TGGTTTTTAGACCCGGCGGACATGGTGCTTTAATTGAAAACCTGAATAATCTGGATTCAGACATTATTTTTATTAAAAAT
ATTGATAATGTAATTCAAAATCATATTGATAAAATTGCTTTATATAAAAAGGCTTTAGGAGGAATTTTAATTGAAGTACA
GCAAAAAGTATTTGGATATTTAAAAGCAATTGAAAAAAATGAAGTGAAAGAAGAGGATCTTAAAGAAATCGTTGATGTTT
TAATGCAAAAACTAAACATTCAGATGACTAAAGATTTCAATAAATTTACTTTTGAGAATAAAATCACCAAAATTAAAGAA
CTGTTAGATCGTCCAATACGAGTTTGCGGAATGGTTCGAAATGAGGGAGAACCTGGCGGAGGACCGTTTTGGGTAATGAA
CGATAAAGGCGAGGTCTCTTTGCAGATTGTAGAAACATCACAGGTAGATTTAGCAAATAAAAAACAGCTTGAAGTTCTAG
AAGAAGCTACGCATTTTAACCCGGTAGATTTGGTTTGCGGAATCAAAAATTATAAAGGAGAAAAGTTTGACCTGAAAAAA
TTTGTTGACGAAAAATCGGGATTTATAGTTGAAAAAAGTGTTGAAGGGAAAGCCGTAAAAAGTTATGAACTTCCGGGATT
ATGGAATGGTTCGATGGCAAATTGGCTGACAGTTTTTGTTGCTGTGCCTTTAATTACTTTTAATCCGGTAAAAACGGTAA
ACGATTTATTAAAACCGGCACATCAGCCACAATAA

Upstream 100 bases:

>100_bases
GCGATATTATTGTAGTGCCTCTTTATGCCTATCGCGGCTTGGGGATGTTGTCGCTTCAATATTTAATTTTTACAATTTTA
GCTATTTCAGCTTATTTAGA

Downstream 100 bases:

>100_bases
TGGATAACGAGAAAATCATATCAGAATTAAACTTTAAAGCCGTTCGAAGCAGTGGTGCGGGCGGGCAGAACGTAAACAAA
GTTTCGTCAAAAGTTGTTTT

Product: NAD metabolism ATPase/kinase-like protein

Products: NAD; pyrophosphate [C]

Alternate protein names: None

Number of amino acids: Translated: 704; Mature: 704

Protein sequence:

>704_residues
MEKNLRQQKTNIIKIALFGPESTGKTTLAKQLADHYKTEWVPEFARDYLQERWEENQHICTVDDMMPIAYGQVLLENEKL
TEANKYLFCDTNLMVTKVFSEVYYGFCDPLLNEAALEHDYDLFFLTDIDVPWEKDDIRDTPEGRETVFSVFKQTLIDNKK
PFITLSGNKESRLAKAIMIIDALGALKEKGFSSQDFVEIYNHGIPFENILKQLDIFKNGIAKSSLIRPATINNGILSLSE
VDFKEKASFFDKHKEEFKIKKFVPASGAATRMYKFLTAFLNDFDIEKETINAYINRKKDKELAIFIIGMDKFPFFDDVDK
KLRELYPDFENLERDYKNYYFIKLLLSPEHFNSANKPKAVLPFHLYKTHIATPIEEHLNECVHYATAKRISNLHFTVSEI
HQNLFEKTVDAVKNKVEEHSNVKINIRYSYQNKGTDSINVDVNNKLVRSSNGSLVFRPGGHGALIENLNNLDSDIIFIKN
IDNVIQNHIDKIALYKKALGGILIEVQQKVFGYLKAIEKNEVKEEDLKEIVDVLMQKLNIQMTKDFNKFTFENKITKIKE
LLDRPIRVCGMVRNEGEPGGGPFWVMNDKGEVSLQIVETSQVDLANKKQLEVLEEATHFNPVDLVCGIKNYKGEKFDLKK
FVDEKSGFIVEKSVEGKAVKSYELPGLWNGSMANWLTVFVAVPLITFNPVKTVNDLLKPAHQPQ

Sequences:

>Translated_704_residues
MEKNLRQQKTNIIKIALFGPESTGKTTLAKQLADHYKTEWVPEFARDYLQERWEENQHICTVDDMMPIAYGQVLLENEKL
TEANKYLFCDTNLMVTKVFSEVYYGFCDPLLNEAALEHDYDLFFLTDIDVPWEKDDIRDTPEGRETVFSVFKQTLIDNKK
PFITLSGNKESRLAKAIMIIDALGALKEKGFSSQDFVEIYNHGIPFENILKQLDIFKNGIAKSSLIRPATINNGILSLSE
VDFKEKASFFDKHKEEFKIKKFVPASGAATRMYKFLTAFLNDFDIEKETINAYINRKKDKELAIFIIGMDKFPFFDDVDK
KLRELYPDFENLERDYKNYYFIKLLLSPEHFNSANKPKAVLPFHLYKTHIATPIEEHLNECVHYATAKRISNLHFTVSEI
HQNLFEKTVDAVKNKVEEHSNVKINIRYSYQNKGTDSINVDVNNKLVRSSNGSLVFRPGGHGALIENLNNLDSDIIFIKN
IDNVIQNHIDKIALYKKALGGILIEVQQKVFGYLKAIEKNEVKEEDLKEIVDVLMQKLNIQMTKDFNKFTFENKITKIKE
LLDRPIRVCGMVRNEGEPGGGPFWVMNDKGEVSLQIVETSQVDLANKKQLEVLEEATHFNPVDLVCGIKNYKGEKFDLKK
FVDEKSGFIVEKSVEGKAVKSYELPGLWNGSMANWLTVFVAVPLITFNPVKTVNDLLKPAHQPQ
>Mature_704_residues
MEKNLRQQKTNIIKIALFGPESTGKTTLAKQLADHYKTEWVPEFARDYLQERWEENQHICTVDDMMPIAYGQVLLENEKL
TEANKYLFCDTNLMVTKVFSEVYYGFCDPLLNEAALEHDYDLFFLTDIDVPWEKDDIRDTPEGRETVFSVFKQTLIDNKK
PFITLSGNKESRLAKAIMIIDALGALKEKGFSSQDFVEIYNHGIPFENILKQLDIFKNGIAKSSLIRPATINNGILSLSE
VDFKEKASFFDKHKEEFKIKKFVPASGAATRMYKFLTAFLNDFDIEKETINAYINRKKDKELAIFIIGMDKFPFFDDVDK
KLRELYPDFENLERDYKNYYFIKLLLSPEHFNSANKPKAVLPFHLYKTHIATPIEEHLNECVHYATAKRISNLHFTVSEI
HQNLFEKTVDAVKNKVEEHSNVKINIRYSYQNKGTDSINVDVNNKLVRSSNGSLVFRPGGHGALIENLNNLDSDIIFIKN
IDNVIQNHIDKIALYKKALGGILIEVQQKVFGYLKAIEKNEVKEEDLKEIVDVLMQKLNIQMTKDFNKFTFENKITKIKE
LLDRPIRVCGMVRNEGEPGGGPFWVMNDKGEVSLQIVETSQVDLANKKQLEVLEEATHFNPVDLVCGIKNYKGEKFDLKK
FVDEKSGFIVEKSVEGKAVKSYELPGLWNGSMANWLTVFVAVPLITFNPVKTVNDLLKPAHQPQ

Specific function: NADr Is Bifunctional; It Interacts With Pnuc At Low Internal NAD Levels, Permitting Transport Of Nmn Intact Into The Cell. As NAD Levels Increase Within The Cell, The Affinity Of NADr For The Operator Regions Of NADa, NADb, And Pncb Increases, Repressing

COG id: COG3172

COG function: function code H; Predicted ATPase/kinase involved in NAD metabolism

Gene ontology:

Cell location: May Loosely Associate With The Membrane Through Its Interaction With The Membrane-Bound Pnuc [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082440, Length=124, Percent_Identity=30.6451612903226, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 80956; Mature: 80956

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNLRQQKTNIIKIALFGPESTGKTTLAKQLADHYKTEWVPEFARDYLQERWEENQHIC
CCCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEE
TVDDMMPIAYGQVLLENEKLTEANKYLFCDTNLMVTKVFSEVYYGFCDPLLNEAALEHDY
EHHHCCHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DLFFLTDIDVPWEKDDIRDTPEGRETVFSVFKQTLIDNKKPFITLSGNKESRLAKAIMII
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHH
DALGALKEKGFSSQDFVEIYNHGIPFENILKQLDIFKNGIAKSSLIRPATINNGILSLSE
HHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEHHH
VDFKEKASFFDKHKEEFKIKKFVPASGAATRMYKFLTAFLNDFDIEKETINAYINRKKDK
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
ELAIFIIGMDKFPFFDDVDKKLRELYPDFENLERDYKNYYFIKLLLSPEHFNSANKPKAV
EEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEEECCHHCCCCCCCCEE
LPFHLYKTHIATPIEEHLNECVHYATAKRISNLHFTVSEIHQNLFEKTVDAVKNKVEEHS
ECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
NVKINIRYSYQNKGTDSINVDVNNKLVRSSNGSLVFRPGGHGALIENLNNLDSDIIFIKN
CEEEEEEEEECCCCCCEEEEECCCCEEECCCCCEEEECCCCCHHHHHHCCCCCCEEEEEC
IDNVIQNHIDKIALYKKALGGILIEVQQKVFGYLKAIEKNEVKEEDLKEIVDVLMQKLNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
QMTKDFNKFTFENKITKIKELLDRPIRVCGMVRNEGEPGGGPFWVMNDKGEVSLQIVETS
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEEEC
QVDLANKKQLEVLEEATHFNPVDLVCGIKNYKGEKFDLKKFVDEKSGFIVEKSVEGKAVK
CCCCCCHHHHHHHHHHHCCCCHHEEECCCCCCCCCCHHHHHHCCCCCEEEEECCCCCEEE
SYELPGLWNGSMANWLTVFVAVPLITFNPVKTVNDLLKPAHQPQ
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEKNLRQQKTNIIKIALFGPESTGKTTLAKQLADHYKTEWVPEFARDYLQERWEENQHIC
CCCCHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEE
TVDDMMPIAYGQVLLENEKLTEANKYLFCDTNLMVTKVFSEVYYGFCDPLLNEAALEHDY
EHHHCCHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DLFFLTDIDVPWEKDDIRDTPEGRETVFSVFKQTLIDNKKPFITLSGNKESRLAKAIMII
CEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHH
DALGALKEKGFSSQDFVEIYNHGIPFENILKQLDIFKNGIAKSSLIRPATINNGILSLSE
HHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCEEHHH
VDFKEKASFFDKHKEEFKIKKFVPASGAATRMYKFLTAFLNDFDIEKETINAYINRKKDK
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
ELAIFIIGMDKFPFFDDVDKKLRELYPDFENLERDYKNYYFIKLLLSPEHFNSANKPKAV
EEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHCCCEEEEEEEECCHHCCCCCCCCEE
LPFHLYKTHIATPIEEHLNECVHYATAKRISNLHFTVSEIHQNLFEKTVDAVKNKVEEHS
ECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
NVKINIRYSYQNKGTDSINVDVNNKLVRSSNGSLVFRPGGHGALIENLNNLDSDIIFIKN
CEEEEEEEEECCCCCCEEEEECCCCEEECCCCCEEEECCCCCHHHHHHCCCCCCEEEEEC
IDNVIQNHIDKIALYKKALGGILIEVQQKVFGYLKAIEKNEVKEEDLKEIVDVLMQKLNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
QMTKDFNKFTFENKITKIKELLDRPIRVCGMVRNEGEPGGGPFWVMNDKGEVSLQIVETS
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEEEC
QVDLANKKQLEVLEEATHFNPVDLVCGIKNYKGEKFDLKKFVDEKSGFIVEKSVEGKAVK
CCCCCCHHHHHHHHHHHCCCCHHEEECCCCCCCCCCHHHHHHCCCCCEEEEECCCCCEEE
SYELPGLWNGSMANWLTVFVAVPLITFNPVKTVNDLLKPAHQPQ
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide; ATP [C]

Specific reaction: nicotinamide nucleotide + ATP = NAD + pyrophosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA