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The map label for this gene is yfjD [C]

Identifier: 146299299

GI number: 146299299

Start: 1776447

End: 1777742

Strand: Direct

Name: yfjD [C]

Synonym: Fjoh_1539

Alternate gene names: 146299299

Gene position: 1776447-1777742 (Clockwise)

Preceding gene: 146299298

Following gene: 146299300

Centisome position: 29.14

GC content: 32.33

Gene sequence:

>1296_bases
TTGGACCCGGAGCCCAGTTTATTTTTTACTACAACTTTAGACACCAATTTAATTATTGGTTTTGTCGGAATATTTATTTT
GCTGTTTTTGTCAGCAATTGTTTCAGGTGCCGAAGTTGCACTTTTTTCTTTATCTCAAAAAGATATCGATGATACTCTTC
AGGAAAATGACTCAAAAGGAAAAATCATCTCCAACCTTTTAGACAGACCCAAAAAGCTCTTAGCGACGTTATTAGTAGCC
AATAATTTTTTAAATATTGGAGTTGTTATCCTGTTTTCTTTTATAGGAAGAAACATTTTTTCGGGCGTTGAGTCTCCTGT
TTTAAAATTTATTTTAGAAGTAATCCTGGTTACTTTTTTTATTTTATTGTTTGGAGAAGTACTTCCAAAAGTATACGCCA
GCCGAAACAATATTAAATTTGCCAAACGTTTTGCCTATTCCATTTCAATTTTAGATAAATTACTGTCGCCAATTAGCTTG
CCTATGCGCAGGGTTACTTTATATTTGCACAATAAATTAGGAAAACAAAAAAATAATTTTTCGATTAACCAGCTTTCTCA
GGCTTTAGAATTAACAGATTCTGAAGGAACATCAACAGAAGAACAAAAAATTCTGGAAGGAATTGTTTCTTTTGGAAATA
CAGATACAAAGCAGGTTATGAGTCCGAGGATTGATATATTTGCTCTGGAAATAACAGAACCATTTTCTGCAATCTGCCCT
AAAATAATCGAAAAAGGATTTTCGAGAATTCCGGTTTATCGTGATAATATTGACCAGATTGAAGGCGTTTTATTCGTAAA
AGATTTATTGCCTCATATCGACAAAGACGATTTTGACTGGGCTTCTTTAATGCGCGAACCATTTTTTGTTCCTGAGAATA
AAAAACTGGATAATCTGCTAAAAGATTTTCAAAGCCTAAAAAGTCATCTTGCTATTGTAGTAGACGAATATGGCGGTACA
TCAGGATTGGTTTCTCTTGAAGATGTAATCGAAGAAATAGTAGGGGATATAAGCGATGAATTTGATGACGAGAATTTGAA
TTTCTCTCAAATTGACGAAAAGAATTTTCTTTTTGAAGGAAAAATAAATCTTAAAGATTTCTACAGAATTGTTGATGTTG
ATGAAGATGTATTTGAAGCCAGTAAAGGCGAAGCTGAAACTTTAGCCGGTTTTATTCTGGAAATTCTGGGTAATTTTCCT
AAAAAAGATCAAAAAATAGCTTTTGAGAATTGTGTTTTTACAATAGAAACCGTTGACAAAAAGCGTGTAAAACAAATAAA
AGTAACAATAGAATAA

Upstream 100 bases:

>100_bases
AAGATCAGGAATCAGCAAAAAACACTAACTTTGATGCACCCAGCGAAGGCTTGCCAATAAATGACCTGCCTTTTTGATTG
TTTAACTAATCTTATGTAAT

Downstream 100 bases:

>100_bases
ATGTTAAAAAAAATCCTTTCAGTAACTGCAATTTTGCTGACATTAACAGTCGTAAGCTGTAAAGACGATGTGCTGCCAAA
ACCTGCAGGTTTCCTGAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MDPEPSLFFTTTLDTNLIIGFVGIFILLFLSAIVSGAEVALFSLSQKDIDDTLQENDSKGKIISNLLDRPKKLLATLLVA
NNFLNIGVVILFSFIGRNIFSGVESPVLKFILEVILVTFFILLFGEVLPKVYASRNNIKFAKRFAYSISILDKLLSPISL
PMRRVTLYLHNKLGKQKNNFSINQLSQALELTDSEGTSTEEQKILEGIVSFGNTDTKQVMSPRIDIFALEITEPFSAICP
KIIEKGFSRIPVYRDNIDQIEGVLFVKDLLPHIDKDDFDWASLMREPFFVPENKKLDNLLKDFQSLKSHLAIVVDEYGGT
SGLVSLEDVIEEIVGDISDEFDDENLNFSQIDEKNFLFEGKINLKDFYRIVDVDEDVFEASKGEAETLAGFILEILGNFP
KKDQKIAFENCVFTIETVDKKRVKQIKVTIE

Sequences:

>Translated_431_residues
MDPEPSLFFTTTLDTNLIIGFVGIFILLFLSAIVSGAEVALFSLSQKDIDDTLQENDSKGKIISNLLDRPKKLLATLLVA
NNFLNIGVVILFSFIGRNIFSGVESPVLKFILEVILVTFFILLFGEVLPKVYASRNNIKFAKRFAYSISILDKLLSPISL
PMRRVTLYLHNKLGKQKNNFSINQLSQALELTDSEGTSTEEQKILEGIVSFGNTDTKQVMSPRIDIFALEITEPFSAICP
KIIEKGFSRIPVYRDNIDQIEGVLFVKDLLPHIDKDDFDWASLMREPFFVPENKKLDNLLKDFQSLKSHLAIVVDEYGGT
SGLVSLEDVIEEIVGDISDEFDDENLNFSQIDEKNFLFEGKINLKDFYRIVDVDEDVFEASKGEAETLAGFILEILGNFP
KKDQKIAFENCVFTIETVDKKRVKQIKVTIE
>Mature_431_residues
MDPEPSLFFTTTLDTNLIIGFVGIFILLFLSAIVSGAEVALFSLSQKDIDDTLQENDSKGKIISNLLDRPKKLLATLLVA
NNFLNIGVVILFSFIGRNIFSGVESPVLKFILEVILVTFFILLFGEVLPKVYASRNNIKFAKRFAYSISILDKLLSPISL
PMRRVTLYLHNKLGKQKNNFSINQLSQALELTDSEGTSTEEQKILEGIVSFGNTDTKQVMSPRIDIFALEITEPFSAICP
KIIEKGFSRIPVYRDNIDQIEGVLFVKDLLPHIDKDDFDWASLMREPFFVPENKKLDNLLKDFQSLKSHLAIVVDEYGGT
SGLVSLEDVIEEIVGDISDEFDDENLNFSQIDEKNFLFEGKINLKDFYRIVDVDEDVFEASKGEAETLAGFILEILGNFP
KKDQKIAFENCVFTIETVDKKRVKQIKVTIE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=395, Percent_Identity=24.3037974683544, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI40068053, Length=379, Percent_Identity=28.2321899736148, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI40068055, Length=379, Percent_Identity=28.2321899736148, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI94681046, Length=372, Percent_Identity=27.1505376344086, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI40068049, Length=251, Percent_Identity=30.2788844621514, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI40068051, Length=337, Percent_Identity=25.8160237388724, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI145693175, Length=410, Percent_Identity=25.1219512195122, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786879, Length=232, Percent_Identity=30.6034482758621, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790664, Length=433, Percent_Identity=22.4018475750577, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082033, Length=338, Percent_Identity=24.5562130177515, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788119, Length=277, Percent_Identity=24.5487364620939, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17539402, Length=365, Percent_Identity=28.2191780821918, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71980512, Length=358, Percent_Identity=26.8156424581006, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17550766, Length=319, Percent_Identity=25.705329153605, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324512, Length=339, Percent_Identity=25.9587020648968, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48668; Mature: 48668

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPEPSLFFTTTLDTNLIIGFVGIFILLFLSAIVSGAEVALFSLSQKDIDDTLQENDSKG
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCHHHHHHHHHCCCCCH
KIISNLLDRPKKLLATLLVANNFLNIGVVILFSFIGRNIFSGVESPVLKFILEVILVTFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLFGEVLPKVYASRNNIKFAKRFAYSISILDKLLSPISLPMRRVTLYLHNKLGKQKNNF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SINQLSQALELTDSEGTSTEEQKILEGIVSFGNTDTKQVMSPRIDIFALEITEPFSAICP
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEECCCHHHHHH
KIIEKGFSRIPVYRDNIDQIEGVLFVKDLLPHIDKDDFDWASLMREPFFVPENKKLDNLL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHH
KDFQSLKSHLAIVVDEYGGTSGLVSLEDVIEEIVGDISDEFDDENLNFSQIDEKNFLFEG
HHHHHHHHHHEEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEC
KINLKDFYRIVDVDEDVFEASKGEAETLAGFILEILGNFPKKDQKIAFENCVFTIETVDK
CCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHEEEEEHHCH
KRVKQIKVTIE
HHHHHEEEEEC
>Mature Secondary Structure
MDPEPSLFFTTTLDTNLIIGFVGIFILLFLSAIVSGAEVALFSLSQKDIDDTLQENDSKG
CCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHEEECCHHHHHHHHHCCCCCH
KIISNLLDRPKKLLATLLVANNFLNIGVVILFSFIGRNIFSGVESPVLKFILEVILVTFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLFGEVLPKVYASRNNIKFAKRFAYSISILDKLLSPISLPMRRVTLYLHNKLGKQKNNF
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SINQLSQALELTDSEGTSTEEQKILEGIVSFGNTDTKQVMSPRIDIFALEITEPFSAICP
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEEECCCHHHHHH
KIIEKGFSRIPVYRDNIDQIEGVLFVKDLLPHIDKDDFDWASLMREPFFVPENKKLDNLL
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHH
KDFQSLKSHLAIVVDEYGGTSGLVSLEDVIEEIVGDISDEFDDENLNFSQIDEKNFLFEG
HHHHHHHHHHEEEEECCCCCCCCEEHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEC
KINLKDFYRIVDVDEDVFEASKGEAETLAGFILEILGNFPKKDQKIAFENCVFTIETVDK
CCCHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHEEEEEHHCH
KRVKQIKVTIE
HHHHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]