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The map label for this gene is dtpA [H]

Identifier: 146299180

GI number: 146299180

Start: 1629141

End: 1630817

Strand: Direct

Name: dtpA [H]

Synonym: Fjoh_1420

Alternate gene names: 146299180

Gene position: 1629141-1630817 (Clockwise)

Preceding gene: 146299179

Following gene: 146299181

Centisome position: 26.72

GC content: 35.06

Gene sequence:

>1677_bases
ATGGGAGAAACTCAAGTAAAAACTGCGCATCCAAAAGGTCTTTGGGTACTATTCGGAACGGAGATGTGGGAGCGATTCAA
TTTTTATGGAATGCGCGCTTTATTAACTTTATTTCTTGTGAATTCATTATTGATGAAGGAAGAAGAAGCGTCTCTAATTT
ATGGAGGTTTCCTTGGACTTTGTTATTTAACACCAATGCTGGGTGGTTTTGTTGCTGACCGTTATTTAGGAAACAGAAAT
TGTATTCTATTAGGCGGATTATTAATGGCAATAGGACAAATGCTTTTGTTTACCAGCGGAAGCGTTTTTGAGTCAAATTT
AGATCTGGCAAAAATCATTATGTACTCTGCATTAGGAGTAATTGTTTTTGGAAACGGATTCTTTAAACCAAACATTTCTA
GTATGGTTGGAAGTTTGTATCCAAAACAAGAAAAAACAAAATTAGATAGTGCTTTCACTATTTTCTATATGGGGATTAAC
ATTGGGGCATTCTTAGGTCAGTCTATTTGTCCTTTATTAGGAGATGTTAAAGATGCAGGCGGTATTAGAGATATCCACGC
TTTTAGATGGGGATTCATGGCGGCTTCTGCAGCAATGTTGTTAGGTACAATTCTTTTTTACTTCTTAAAAAATAAATATG
TAGTTTCTCCAGAAGGAAAACCGCTAGGAGGACTTCCTTCAAAAAATGATGCTTCAGATTTTGAAGAAGGAGAATCACAA
AAAGCAAACTTTTCTAATAAAGCTCTTGCTATGGCAGGAGTAGCATTTATTGCTTTAGGGTTCTTTTTTCACTATGTGGT
AGGTCAAAACTTAATTTATACTTTGATTTACTCAAGTGGTCTTGCATTGGCAGGATTGATTATTTCTGATACTTCTTTGA
CTAAAGTAGAAAGAGACAGAATTATTGTAATTTACATTGTATCGTTCTTTATTATCTTCTTCTGGGCGGCGTTTGAGCAG
GCAGGTTCATCTTTGACTTTTATTGCTGATAACCAAACAGACAGACATTTCTTTGGCTGGGCAATGCCGCCATCGATGGT
TCAAATTTTTAACGGTATGTTTGTTGTGTTTTTAGCAGTTCCATTTAGTGTTCTTTGGGATACTTTAAGAGCTAAAGGCA
AAGAGCCAATCTCACCTGTAAAATTAGCTGCTGGGTTAGTGATAATTTCTGTGAGTTTCTTTATGATTGCGACTCAGGTT
TCTTATATCGGAACTTCAGGACTTTTATTAGTAAAATGGCTTATCTTATTATATTTCCTAAATACATGTGCTGAGTTATG
TTTGTCTCCAATTGGTTTGTCGTTGGTGGGTAAATTGTCACCAAAACGTTTTGCATCATTGTTATACGGAGTATTCTTTT
TGTCTAATGCATCAGGTTATGCTTTAGGAGGAACTTTAGGTTCTATCTTGCCTGCAACCGGAGATAAATTTGCAAAAGCA
AAAGAACTTGGAATAGATCTTCAGGCAGTTTTAGATAAAAAAATCACATTGACAGCAGATCAGTTGTCTTTATTAGATCA
TCATCAAATTAGTGCTCAAAACCCAATTTTTGCAGGATTTGAAATCCATAATTTATATGAGTTCTTTATGGTTTTTGTTG
TTCTGACAGGTATTGCGGCAATTTTATTATTTGCTTTAACACCACTATTGAAAAAATTAATGCACGGTGTTAGATAA

Upstream 100 bases:

>100_bases
GGCGGAAAAACGAGAGTTCAGCTTTACAATAAAATGACCAATTTTATCAAAGAAAATTTATAATCTAAAACAATATTAAC
CTAAAAATAATAATGAAAAT

Downstream 100 bases:

>100_bases
AATATAAAATGGAAAACAATATTACTTTAGAAGAAATTCAAAATTTTAAAGGCAAGTACCCAAAACAATTGTGGTACTTG
TTTTTGGTTGAAATGTGGGA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MGETQVKTAHPKGLWVLFGTEMWERFNFYGMRALLTLFLVNSLLMKEEEASLIYGGFLGLCYLTPMLGGFVADRYLGNRN
CILLGGLLMAIGQMLLFTSGSVFESNLDLAKIIMYSALGVIVFGNGFFKPNISSMVGSLYPKQEKTKLDSAFTIFYMGIN
IGAFLGQSICPLLGDVKDAGGIRDIHAFRWGFMAASAAMLLGTILFYFLKNKYVVSPEGKPLGGLPSKNDASDFEEGESQ
KANFSNKALAMAGVAFIALGFFFHYVVGQNLIYTLIYSSGLALAGLIISDTSLTKVERDRIIVIYIVSFFIIFFWAAFEQ
AGSSLTFIADNQTDRHFFGWAMPPSMVQIFNGMFVVFLAVPFSVLWDTLRAKGKEPISPVKLAAGLVIISVSFFMIATQV
SYIGTSGLLLVKWLILLYFLNTCAELCLSPIGLSLVGKLSPKRFASLLYGVFFLSNASGYALGGTLGSILPATGDKFAKA
KELGIDLQAVLDKKITLTADQLSLLDHHQISAQNPIFAGFEIHNLYEFFMVFVVLTGIAAILLFALTPLLKKLMHGVR

Sequences:

>Translated_558_residues
MGETQVKTAHPKGLWVLFGTEMWERFNFYGMRALLTLFLVNSLLMKEEEASLIYGGFLGLCYLTPMLGGFVADRYLGNRN
CILLGGLLMAIGQMLLFTSGSVFESNLDLAKIIMYSALGVIVFGNGFFKPNISSMVGSLYPKQEKTKLDSAFTIFYMGIN
IGAFLGQSICPLLGDVKDAGGIRDIHAFRWGFMAASAAMLLGTILFYFLKNKYVVSPEGKPLGGLPSKNDASDFEEGESQ
KANFSNKALAMAGVAFIALGFFFHYVVGQNLIYTLIYSSGLALAGLIISDTSLTKVERDRIIVIYIVSFFIIFFWAAFEQ
AGSSLTFIADNQTDRHFFGWAMPPSMVQIFNGMFVVFLAVPFSVLWDTLRAKGKEPISPVKLAAGLVIISVSFFMIATQV
SYIGTSGLLLVKWLILLYFLNTCAELCLSPIGLSLVGKLSPKRFASLLYGVFFLSNASGYALGGTLGSILPATGDKFAKA
KELGIDLQAVLDKKITLTADQLSLLDHHQISAQNPIFAGFEIHNLYEFFMVFVVLTGIAAILLFALTPLLKKLMHGVR
>Mature_557_residues
GETQVKTAHPKGLWVLFGTEMWERFNFYGMRALLTLFLVNSLLMKEEEASLIYGGFLGLCYLTPMLGGFVADRYLGNRNC
ILLGGLLMAIGQMLLFTSGSVFESNLDLAKIIMYSALGVIVFGNGFFKPNISSMVGSLYPKQEKTKLDSAFTIFYMGINI
GAFLGQSICPLLGDVKDAGGIRDIHAFRWGFMAASAAMLLGTILFYFLKNKYVVSPEGKPLGGLPSKNDASDFEEGESQK
ANFSNKALAMAGVAFIALGFFFHYVVGQNLIYTLIYSSGLALAGLIISDTSLTKVERDRIIVIYIVSFFIIFFWAAFEQA
GSSLTFIADNQTDRHFFGWAMPPSMVQIFNGMFVVFLAVPFSVLWDTLRAKGKEPISPVKLAAGLVIISVSFFMIATQVS
YIGTSGLLLVKWLILLYFLNTCAELCLSPIGLSLVGKLSPKRFASLLYGVFFLSNASGYALGGTLGSILPATGDKFAKAK
ELGIDLQAVLDKKITLTADQLSLLDHHQISAQNPIFAGFEIHNLYEFFMVFVVLTGIAAILLFALTPLLKKLMHGVR

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=399, Percent_Identity=25.31328320802, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI226371746, Length=191, Percent_Identity=30.3664921465969, Blast_Score=89, Evalue=9e-18,
Organism=Escherichia coli, GI1787922, Length=473, Percent_Identity=28.1183932346723, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1789911, Length=465, Percent_Identity=28.1720430107527, Blast_Score=173, Evalue=3e-44,
Organism=Escherichia coli, GI1786927, Length=457, Percent_Identity=29.5404814004376, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1790572, Length=453, Percent_Identity=24.7240618101545, Blast_Score=135, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17569141, Length=392, Percent_Identity=25, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17541704, Length=392, Percent_Identity=24.234693877551, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71987453, Length=189, Percent_Identity=30.6878306878307, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28571098, Length=394, Percent_Identity=25.1269035532995, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28571102, Length=394, Percent_Identity=25.1269035532995, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI28571100, Length=394, Percent_Identity=25.1269035532995, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24639585, Length=355, Percent_Identity=26.4788732394366, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24639583, Length=355, Percent_Identity=26.4788732394366, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24639581, Length=355, Percent_Identity=26.4788732394366, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 61094; Mature: 60963

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGETQVKTAHPKGLWVLFGTEMWERFNFYGMRALLTLFLVNSLLMKEEEASLIYGGFLGL
CCCCCCEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
CYLTPMLGGFVADRYLGNRNCILLGGLLMAIGQMLLFTSGSVFESNLDLAKIIMYSALGV
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH
IVFGNGFFKPNISSMVGSLYPKQEKTKLDSAFTIFYMGINIGAFLGQSICPLLGDVKDAG
EEECCCCCCCCHHHHHHHCCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCC
GIRDIHAFRWGFMAASAAMLLGTILFYFLKNKYVVSPEGKPLGGLPSKNDASDFEEGESQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCHHHCCCCC
KANFSNKALAMAGVAFIALGFFFHYVVGQNLIYTLIYSSGLALAGLIISDTSLTKVERDR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCHHHHHCCCC
IIVIYIVSFFIIFFWAAFEQAGSSLTFIADNQTDRHFFGWAMPPSMVQIFNGMFVVFLAV
EEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
PFSVLWDTLRAKGKEPISPVKLAAGLVIISVSFFMIATQVSYIGTSGLLLVKWLILLYFL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NTCAELCLSPIGLSLVGKLSPKRFASLLYGVFFLSNASGYALGGTLGSILPATGDKFAKA
HHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEECCHHHHHCCCCCCHHHHH
KELGIDLQAVLDKKITLTADQLSLLDHHQISAQNPIFAGFEIHNLYEFFMVFVVLTGIAA
HHHCCCHHHHHCCCEEEEHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
ILLFALTPLLKKLMHGVR
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GETQVKTAHPKGLWVLFGTEMWERFNFYGMRALLTLFLVNSLLMKEEEASLIYGGFLGL
CCCCCEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
CYLTPMLGGFVADRYLGNRNCILLGGLLMAIGQMLLFTSGSVFESNLDLAKIIMYSALGV
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHH
IVFGNGFFKPNISSMVGSLYPKQEKTKLDSAFTIFYMGINIGAFLGQSICPLLGDVKDAG
EEECCCCCCCCHHHHHHHCCCCHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCC
GIRDIHAFRWGFMAASAAMLLGTILFYFLKNKYVVSPEGKPLGGLPSKNDASDFEEGESQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCHHHCCCCC
KANFSNKALAMAGVAFIALGFFFHYVVGQNLIYTLIYSSGLALAGLIISDTSLTKVERDR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEECCCHHHHHCCCC
IIVIYIVSFFIIFFWAAFEQAGSSLTFIADNQTDRHFFGWAMPPSMVQIFNGMFVVFLAV
EEHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
PFSVLWDTLRAKGKEPISPVKLAAGLVIISVSFFMIATQVSYIGTSGLLLVKWLILLYFL
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
NTCAELCLSPIGLSLVGKLSPKRFASLLYGVFFLSNASGYALGGTLGSILPATGDKFAKA
HHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHCCCCCCEECCHHHHHCCCCCCHHHHH
KELGIDLQAVLDKKITLTADQLSLLDHHQISAQNPIFAGFEIHNLYEFFMVFVVLTGIAA
HHHCCCHHHHHCCCEEEEHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
ILLFALTPLLKKLMHGVR
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]