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The map label for this gene is yeeO [C]

Identifier: 146298832

GI number: 146298832

Start: 1214147

End: 1215574

Strand: Direct

Name: yeeO [C]

Synonym: Fjoh_1071

Alternate gene names: 146298832

Gene position: 1214147-1215574 (Clockwise)

Preceding gene: 146298831

Following gene: 146298833

Centisome position: 19.91

GC content: 35.64

Gene sequence:

>1428_bases
ATGACAGAAACAACTATAAAGGAAACTTTCATTTCCAAAATTTTTACCACTTTAAAACAAGCTTTAAAAGGCGACGAATC
ATTTGATTATACTTCTGGAAGTATCAAAAAAGCCGTAATTCTATTAGCCATTCCTATGGTTTTAGAAATGATGATGGAAT
CGGTTTTTGCTTTAGTAGATTTATATTTCGTTGGTCATTTAAAACACAGCAGTTTTGCCATTCAAACAGTAGGTCTTACA
GAATCTGTCTTGACCATTATATATTCTCTTGCAATAGGGATGAGTATGGCAGCAACGGCAGTTGTAGCACGCCGAATTGG
AGAAAAAGATCCAATTGCTGCCGCAAAAGCCGGAATGCAGGCCATAATTATAGCCTTTGCAGTTAACAGTTTATTGAGCA
TTTTTGGAATTATTTATGCTAAAGATATTCTGATTGTAATGGGTTCTTCAATAGAATCAGCCGAACACGGTTACCGATTT
ACTCAAATTATGATTGGTTCCAGTTTATGCATTATGCTTTTATTCCTGATTAACGGAATTTTTCGCGGTGCCGGCAATGC
AGCAATTGCAATGAAAAGTCTTTGGATTGCCAACATTTGTAATATTATTTTATGCCCAATTTTAATTAATGGCTTAGGAC
CAGTTCCGGCTTTTGGTTTAATAGGAGCAGCTATTGCGACAACTTTAGGAAGAAGTATTGGAGTTTTATATCAGGTATAT
CATTTGTTTTTTGGTAACGGAGTTTTAAAAATTAAAATTGCTTATTTCGCACCAGATTTCAAACAAATAAAAGCTTTGGT
TAAAATCGCTGCTCCTGGAATTTTACAATTTGTAATCGCATCCTGCAGCTGGATTTTCCTGGCACAATTAGTTGCTACAA
CAGGAGGAGATCATGGTTCTGCTGGATATCAGACAGCGTTGAGAATTATGATGTTTTTCATACTTCCTGCTTGGGGATTA
AGTAATGCCGCTGCTACTTTAGTGGGGCAGAATTTAGGAGCAAAACAAATTGAACGTGCCGAAAAATCGGTTTACACTAC
GGCAAGATATAATGTAATTTTCATGGCTTCGATTATGGTTATTACTTTAGTTTTTGGCCAATATATTATTTCGTTTTTTA
CGAATGATGAAATGGTAAAAACAGTTGCGATTGAAGCTTTACAAATTATGAGTATCGGATTTATCTTTTACGGAATAGGA
ATGGTTTTAATCAATACTTTCAACGGAGCGGGAGATACCTGGACACCAACCGGAATTAACTTTTTTGGATTTTGGCTGTT
TCAAATTCCGCTTGCTTTTGTGTTAGCCAAACATTTTAATATGGGACCAACCGGAGTTTTTATTGCTATTCCTGTTGCTG
AAACTGCAATAACTCTAGCCGGAATTTTTTTCTATAAAAGAGGAAAGTGGAAACGAGTTCAAGTATAA

Upstream 100 bases:

>100_bases
CCTAATTTTATTTTTTAGAATAATTAGGATACTTACGTTTTTACTTTTTTAGTTCAGATTTATACATCTGGACAAATTTT
ATCATTTATCCTAACATATC

Downstream 100 bases:

>100_bases
TTGAATAATTTTTACATGTAAAGTATTACAAATTGTTATATATATTTGTGCTCTAGAAAATTATAATGATTTAAAAATGA
ATTTAGTGAGTATTAGAGAT

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 474

Protein sequence:

>475_residues
MTETTIKETFISKIFTTLKQALKGDESFDYTSGSIKKAVILLAIPMVLEMMMESVFALVDLYFVGHLKHSSFAIQTVGLT
ESVLTIIYSLAIGMSMAATAVVARRIGEKDPIAAAKAGMQAIIIAFAVNSLLSIFGIIYAKDILIVMGSSIESAEHGYRF
TQIMIGSSLCIMLLFLINGIFRGAGNAAIAMKSLWIANICNIILCPILINGLGPVPAFGLIGAAIATTLGRSIGVLYQVY
HLFFGNGVLKIKIAYFAPDFKQIKALVKIAAPGILQFVIASCSWIFLAQLVATTGGDHGSAGYQTALRIMMFFILPAWGL
SNAAATLVGQNLGAKQIERAEKSVYTTARYNVIFMASIMVITLVFGQYIISFFTNDEMVKTVAIEALQIMSIGFIFYGIG
MVLINTFNGAGDTWTPTGINFFGFWLFQIPLAFVLAKHFNMGPTGVFIAIPVAETAITLAGIFFYKRGKWKRVQV

Sequences:

>Translated_475_residues
MTETTIKETFISKIFTTLKQALKGDESFDYTSGSIKKAVILLAIPMVLEMMMESVFALVDLYFVGHLKHSSFAIQTVGLT
ESVLTIIYSLAIGMSMAATAVVARRIGEKDPIAAAKAGMQAIIIAFAVNSLLSIFGIIYAKDILIVMGSSIESAEHGYRF
TQIMIGSSLCIMLLFLINGIFRGAGNAAIAMKSLWIANICNIILCPILINGLGPVPAFGLIGAAIATTLGRSIGVLYQVY
HLFFGNGVLKIKIAYFAPDFKQIKALVKIAAPGILQFVIASCSWIFLAQLVATTGGDHGSAGYQTALRIMMFFILPAWGL
SNAAATLVGQNLGAKQIERAEKSVYTTARYNVIFMASIMVITLVFGQYIISFFTNDEMVKTVAIEALQIMSIGFIFYGIG
MVLINTFNGAGDTWTPTGINFFGFWLFQIPLAFVLAKHFNMGPTGVFIAIPVAETAITLAGIFFYKRGKWKRVQV
>Mature_474_residues
TETTIKETFISKIFTTLKQALKGDESFDYTSGSIKKAVILLAIPMVLEMMMESVFALVDLYFVGHLKHSSFAIQTVGLTE
SVLTIIYSLAIGMSMAATAVVARRIGEKDPIAAAKAGMQAIIIAFAVNSLLSIFGIIYAKDILIVMGSSIESAEHGYRFT
QIMIGSSLCIMLLFLINGIFRGAGNAAIAMKSLWIANICNIILCPILINGLGPVPAFGLIGAAIATTLGRSIGVLYQVYH
LFFGNGVLKIKIAYFAPDFKQIKALVKIAAPGILQFVIASCSWIFLAQLVATTGGDHGSAGYQTALRIMMFFILPAWGLS
NAAATLVGQNLGAKQIERAEKSVYTTARYNVIFMASIMVITLVFGQYIISFFTNDEMVKTVAIEALQIMSIGFIFYGIGM
VLINTFNGAGDTWTPTGINFFGFWLFQIPLAFVLAKHFNMGPTGVFIAIPVAETAITLAGIFFYKRGKWKRVQV

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=470, Percent_Identity=25.1063829787234, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 51488; Mature: 51357

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTIKETFISKIFTTLKQALKGDESFDYTSGSIKKAVILLAIPMVLEMMMESVFALVD
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYFVGHLKHSSFAIQTVGLTESVLTIIYSLAIGMSMAATAVVARRIGEKDPIAAAKAGMQ
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AIIIAFAVNSLLSIFGIIYAKDILIVMGSSIESAEHGYRFTQIMIGSSLCIMLLFLINGI
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FRGAGNAAIAMKSLWIANICNIILCPILINGLGPVPAFGLIGAAIATTLGRSIGVLYQVY
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HLFFGNGVLKIKIAYFAPDFKQIKALVKIAAPGILQFVIASCSWIFLAQLVATTGGDHGS
HHHHCCCEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGYQTALRIMMFFILPAWGLSNAAATLVGQNLGAKQIERAEKSVYTTARYNVIFMASIMV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLVFGQYIISFFTNDEMVKTVAIEALQIMSIGFIFYGIGMVLINTFNGAGDTWTPTGIN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
FFGFWLFQIPLAFVLAKHFNMGPTGVFIAIPVAETAITLAGIFFYKRGKWKRVQV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
TETTIKETFISKIFTTLKQALKGDESFDYTSGSIKKAVILLAIPMVLEMMMESVFALVD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYFVGHLKHSSFAIQTVGLTESVLTIIYSLAIGMSMAATAVVARRIGEKDPIAAAKAGMQ
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AIIIAFAVNSLLSIFGIIYAKDILIVMGSSIESAEHGYRFTQIMIGSSLCIMLLFLINGI
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
FRGAGNAAIAMKSLWIANICNIILCPILINGLGPVPAFGLIGAAIATTLGRSIGVLYQVY
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HLFFGNGVLKIKIAYFAPDFKQIKALVKIAAPGILQFVIASCSWIFLAQLVATTGGDHGS
HHHHCCCEEEEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGYQTALRIMMFFILPAWGLSNAAATLVGQNLGAKQIERAEKSVYTTARYNVIFMASIMV
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITLVFGQYIISFFTNDEMVKTVAIEALQIMSIGFIFYGIGMVLINTFNGAGDTWTPTGIN
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
FFGFWLFQIPLAFVLAKHFNMGPTGVFIAIPVAETAITLAGIFFYKRGKWKRVQV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]