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The map label for this gene is lolE [H]

Identifier: 146298831

GI number: 146298831

Start: 1212863

End: 1213975

Strand: Direct

Name: lolE [H]

Synonym: Fjoh_1070

Alternate gene names: 146298831

Gene position: 1212863-1213975 (Clockwise)

Preceding gene: 146298830

Following gene: 146298832

Centisome position: 19.89

GC content: 33.69

Gene sequence:

>1113_bases
ATGGGAATCATTGTTGGGACAATGGCTTTGTTTGTGGTTTTATCTGTTTTTAGCGGATTAAAAGTTTTTAGTCTTTCGTT
CACAAACGAGATCGATCCAGATTTAAAAATGACCAGTACGTTAGGAAAATCATTTTTTATTTCGGCTCAGCAGGAACAAG
ACCTAAAAAAAATAAATGGTGTAGCCTCTTATACTAAAATTATTGAAGAACGTGTTTTGTTTATATTCAAGGATAAACAG
CACGTTACCTATTTAAAAGGTGTTGACAGCCTTTATCCTGTTGTAAACGATATTAAAAGAAAACTCTTTAATGGGCAGTG
GCTAAAACCAGATTCCTATCAGGTAGTTATTGGCTACGGAATTGCACAGGATTTTTCGATGGGAATTCTCGATTTTGAAA
ACCCGCTGCAAATCTTCGCTCCAAAACCGGGAAAAGGTGCAATCGAAAATCCCGAAGAAGCTTTTAATAAAACAGATGTT
CTGCCAGTTGGAATTTACTCAATAAGCGAAGATTTAGATTCTAAATATGTTTTTGCAGATTTAGGTTTAACACAGGAATT
ATTGATGTATAAACCCAATCAGATTTCAGGAATCGAATTTCATCTCAAAGAAAATGCAGATGAAAATGCTGTAAAAGCAC
AGCTTGAAAAGATTTTCAATAATAAAATTACTTTAAAAAACAGGGCACAGTTAAATGAGTCTTTGTACAAAATGCTCAAT
ACCGAAAATATTGCCGTTTATTTAATTTTTACTCTTGTAATTATTGTGGCACTTTTTAACCTGATTGGAGCTTTGATTAT
GATGATTTTAGATAAAAAAGGAAATCTTAAAACCCTTTTTAATCTTGGAACAGAAATCAACAATCTGCGAAAAATATTCC
TGCTTCAGGGAACGCTTCTGAGCATTTTTGGAGGTATTATCGGGTTGGCTTTAGGAATTATTCTAGTGATTCTGCAGCAG
CAATATGAGTTAATTATGATCACGCCGACTTTAGCTTATCCTGTAGTTTTTACACTGGAAAATGTTTTGATCGTAATGGC
AACCATTGTTTCTCTTGGATTTATTGCTTCGTTAATTGCAAGCAGCCGTGTAAGTAAAAAATTACTGGATTAA

Upstream 100 bases:

>100_bases
AGAAAATCATAAATTGAATTTCCCATTTTACATAGCCAAACGTTATATTTTTAGCCGAAGTAAAAACAACGCTATTAATA
TCATTAATTACATTGCCAGC

Downstream 100 bases:

>100_bases
TTTCTTCTTTAAAAATATTACTTATATTTACCGCCTTGAAAATCTACAGCATATGATTGTTTCTGCCTAATCCTAATTTT
ATTTTTTAGAATAATTAGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MGIIVGTMALFVVLSVFSGLKVFSLSFTNEIDPDLKMTSTLGKSFFISAQQEQDLKKINGVASYTKIIEERVLFIFKDKQ
HVTYLKGVDSLYPVVNDIKRKLFNGQWLKPDSYQVVIGYGIAQDFSMGILDFENPLQIFAPKPGKGAIENPEEAFNKTDV
LPVGIYSISEDLDSKYVFADLGLTQELLMYKPNQISGIEFHLKENADENAVKAQLEKIFNNKITLKNRAQLNESLYKMLN
TENIAVYLIFTLVIIVALFNLIGALIMMILDKKGNLKTLFNLGTEINNLRKIFLLQGTLLSIFGGIIGLALGIILVILQQ
QYELIMITPTLAYPVVFTLENVLIVMATIVSLGFIASLIASSRVSKKLLD

Sequences:

>Translated_370_residues
MGIIVGTMALFVVLSVFSGLKVFSLSFTNEIDPDLKMTSTLGKSFFISAQQEQDLKKINGVASYTKIIEERVLFIFKDKQ
HVTYLKGVDSLYPVVNDIKRKLFNGQWLKPDSYQVVIGYGIAQDFSMGILDFENPLQIFAPKPGKGAIENPEEAFNKTDV
LPVGIYSISEDLDSKYVFADLGLTQELLMYKPNQISGIEFHLKENADENAVKAQLEKIFNNKITLKNRAQLNESLYKMLN
TENIAVYLIFTLVIIVALFNLIGALIMMILDKKGNLKTLFNLGTEINNLRKIFLLQGTLLSIFGGIIGLALGIILVILQQ
QYELIMITPTLAYPVVFTLENVLIVMATIVSLGFIASLIASSRVSKKLLD
>Mature_369_residues
GIIVGTMALFVVLSVFSGLKVFSLSFTNEIDPDLKMTSTLGKSFFISAQQEQDLKKINGVASYTKIIEERVLFIFKDKQH
VTYLKGVDSLYPVVNDIKRKLFNGQWLKPDSYQVVIGYGIAQDFSMGILDFENPLQIFAPKPGKGAIENPEEAFNKTDVL
PVGIYSISEDLDSKYVFADLGLTQELLMYKPNQISGIEFHLKENADENAVKAQLEKIFNNKITLKNRAQLNESLYKMLNT
ENIAVYLIFTLVIIVALFNLIGALIMMILDKKGNLKTLFNLGTEINNLRKIFLLQGTLLSIFGGIIGLALGIILVILQQQ
YELIMITPTLAYPVVFTLENVLIVMATIVSLGFIASLIASSRVSKKLLD

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=210, Percent_Identity=25.2380952380952, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925
- InterPro:   IPR011926 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 41282; Mature: 41151

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIIVGTMALFVVLSVFSGLKVFSLSFTNEIDPDLKMTSTLGKSFFISAQQEQDLKKING
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCHHEEECHHHHHHHHHHH
VASYTKIIEERVLFIFKDKQHVTYLKGVDSLYPVVNDIKRKLFNGQWLKPDSYQVVIGYG
HHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
IAQDFSMGILDFENPLQIFAPKPGKGAIENPEEAFNKTDVLPVGIYSISEDLDSKYVFAD
CHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCEEEHHHHHHCCCCCEEEEE
LGLTQELLMYKPNQISGIEFHLKENADENAVKAQLEKIFNNKITLKNRAQLNESLYKMLN
CCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHC
TENIAVYLIFTLVIIVALFNLIGALIMMILDKKGNLKTLFNLGTEINNLRKIFLLQGTLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
SIFGGIIGLALGIILVILQQQYELIMITPTLAYPVVFTLENVLIVMATIVSLGFIASLIA
HHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSRVSKKLLD
HHHHHHHHCC
>Mature Secondary Structure 
GIIVGTMALFVVLSVFSGLKVFSLSFTNEIDPDLKMTSTLGKSFFISAQQEQDLKKING
CCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCHHEEECHHHHHHHHHHH
VASYTKIIEERVLFIFKDKQHVTYLKGVDSLYPVVNDIKRKLFNGQWLKPDSYQVVIGYG
HHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
IAQDFSMGILDFENPLQIFAPKPGKGAIENPEEAFNKTDVLPVGIYSISEDLDSKYVFAD
CHHHCCCCCCCCCCCCEEECCCCCCCCCCCHHHHCCCCCCCEEEHHHHHHCCCCCEEEEE
LGLTQELLMYKPNQISGIEFHLKENADENAVKAQLEKIFNNKITLKNRAQLNESLYKMLN
CCCHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHC
TENIAVYLIFTLVIIVALFNLIGALIMMILDKKGNLKTLFNLGTEINNLRKIFLLQGTLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHH
SIFGGIIGLALGIILVILQQQYELIMITPTLAYPVVFTLENVLIVMATIVSLGFIASLIA
HHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSRVSKKLLD
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]