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The map label for this gene is trpS [H]

Identifier: 146298751

GI number: 146298751

Start: 1129034

End: 1130008

Strand: Direct

Name: trpS [H]

Synonym: Fjoh_0990

Alternate gene names: 146298751

Gene position: 1129034-1130008 (Clockwise)

Preceding gene: 146298749

Following gene: 146298754

Centisome position: 18.52

GC content: 36.1

Gene sequence:

>975_bases
ATGGCAAAAATACTTACTGGTGTTCAGAGTACTGGAACGCCTCACTTAGGAAATCTATTGGGAGCTATCATCCCTGCAAT
TGAGTTATCGAATAATCCGGCAAACGAATCATTTTTGTTTATTGCTGATTTACATTCGATTACACAAATCAAAGATGGTA
AAACATTAAGAGAAAATACCTTTAGTGTGGCTGCTGCATGGCTTGCTTTTGGATTAGATATTGACCGTGTAACTTTTTAC
AGACAGTCAGATGTAGTTCAAACAACTGAATTAACCTGGTATTTAAGCTGCTTTTTCCCGTTTCAGCGTTTAACTTTGGC
ACATTCTTTCAAAGACAAAGCCGATCGTTTAGACGATGTTAACGCCGGACTTTTTACTTATCCAATGTTGATGGCTGCTG
ATATTTTATTGTATGATGCAGAATTTGTTCCTGTTGGAAAAGATCAATTACAGCATATAGAAATTACCCGTGATGTAGCC
TCAAGATTCAACCACCAAATGGGTGAAACTTTTGTACTTCCAGAAGCTAAAATTCAGGAAGACAGCAAATTGATTCCAGG
AACAAATGGAGGAAAAATGAGTAAATCTGCTAATAATTACATCAACATTTTCCTTGATGATAAAGCTTTGCGCAAACAGA
TTATGAGCATTGAAACGGATAGTACACCGCTTGAAGCTCCAAAAAATCCTGATACCTGCAATGCTTTTGCTATTTATTCT
TTAATGGCAGATGAAGCTCAAATTGCAGAAATGAGAGCGAATTATTTAGGCGGAAATTATGGTTATGGCCACGCAAAACA
AGCTATTTTTGAATTGATTACAGAAAAATTCAAAACAGAAAGAGAAAGATATAATTACTATATAAACAATCTTGATGAAG
TTGATGCCTTATTGAAAAAAGGTGCTGCCAAAGCTTCTGCAGTTGCTGACGGAGTTCTGCAAAGAGTTCGTGAGAAACTA
GGATTTGGAAAATAA

Upstream 100 bases:

>100_bases
AATAAACTTTGCGAACTTTGCAGTTAAATTAAAAATAAACTTTGCGAACTTTGCGGTTAAAATTAAACTTGCAATATTTG
CGGTTAAGAAAAAAACTAGA

Downstream 100 bases:

>100_bases
AAACAAATTCAAACACCATATCAAACCTCTTGTTAATACAAGAGGTTTTTTTTATATATTTTTTTGTAACTTCATATAAA
CTAATTATTTATAATTTAAT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAKILTGVQSTGTPHLGNLLGAIIPAIELSNNPANESFLFIADLHSITQIKDGKTLRENTFSVAAAWLAFGLDIDRVTFY
RQSDVVQTTELTWYLSCFFPFQRLTLAHSFKDKADRLDDVNAGLFTYPMLMAADILLYDAEFVPVGKDQLQHIEITRDVA
SRFNHQMGETFVLPEAKIQEDSKLIPGTNGGKMSKSANNYINIFLDDKALRKQIMSIETDSTPLEAPKNPDTCNAFAIYS
LMADEAQIAEMRANYLGGNYGYGHAKQAIFELITEKFKTERERYNYYINNLDEVDALLKKGAAKASAVADGVLQRVREKL
GFGK

Sequences:

>Translated_324_residues
MAKILTGVQSTGTPHLGNLLGAIIPAIELSNNPANESFLFIADLHSITQIKDGKTLRENTFSVAAAWLAFGLDIDRVTFY
RQSDVVQTTELTWYLSCFFPFQRLTLAHSFKDKADRLDDVNAGLFTYPMLMAADILLYDAEFVPVGKDQLQHIEITRDVA
SRFNHQMGETFVLPEAKIQEDSKLIPGTNGGKMSKSANNYINIFLDDKALRKQIMSIETDSTPLEAPKNPDTCNAFAIYS
LMADEAQIAEMRANYLGGNYGYGHAKQAIFELITEKFKTERERYNYYINNLDEVDALLKKGAAKASAVADGVLQRVREKL
GFGK
>Mature_323_residues
AKILTGVQSTGTPHLGNLLGAIIPAIELSNNPANESFLFIADLHSITQIKDGKTLRENTFSVAAAWLAFGLDIDRVTFYR
QSDVVQTTELTWYLSCFFPFQRLTLAHSFKDKADRLDDVNAGLFTYPMLMAADILLYDAEFVPVGKDQLQHIEITRDVAS
RFNHQMGETFVLPEAKIQEDSKLIPGTNGGKMSKSANNYINIFLDDKALRKQIMSIETDSTPLEAPKNPDTCNAFAIYSL
MADEAQIAEMRANYLGGNYGYGHAKQAIFELITEKFKTERERYNYYINNLDEVDALLKKGAAKASAVADGVLQRVREKLG
FGK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=330, Percent_Identity=32.4242424242424, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=42.6136363636364, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1789786, Length=332, Percent_Identity=35.2409638554217, Blast_Score=180, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI71982800, Length=336, Percent_Identity=29.1666666666667, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71982793, Length=337, Percent_Identity=29.080118694362, Blast_Score=135, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6320474, Length=351, Percent_Identity=32.1937321937322, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24666151, Length=333, Percent_Identity=33.6336336336336, Blast_Score=166, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 36157; Mature: 36025

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILTGVQSTGTPHLGNLLGAIIPAIELSNNPANESFLFIADLHSITQIKDGKTLRENT
CCCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHCCCCCHHHHH
FSVAAAWLAFGLDIDRVTFYRQSDVVQTTELTWYLSCFFPFQRLTLAHSFKDKADRLDDV
HHHHHHHHHHCCCHHHEEEEECCCCEEHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
NAGLFTYPMLMAADILLYDAEFVPVGKDQLQHIEITRDVASRFNHQMGETFVLPEAKIQE
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHCC
DSKLIPGTNGGKMSKSANNYINIFLDDKALRKQIMSIETDSTPLEAPKNPDTCNAFAIYS
CCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
LMADEAQIAEMRANYLGGNYGYGHAKQAIFELITEKFKTERERYNYYINNLDEVDALLKK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GAAKASAVADGVLQRVREKLGFGK
CCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AKILTGVQSTGTPHLGNLLGAIIPAIELSNNPANESFLFIADLHSITQIKDGKTLRENT
CCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHCCCCCHHHHH
FSVAAAWLAFGLDIDRVTFYRQSDVVQTTELTWYLSCFFPFQRLTLAHSFKDKADRLDDV
HHHHHHHHHHCCCHHHEEEEECCCCEEHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
NAGLFTYPMLMAADILLYDAEFVPVGKDQLQHIEITRDVASRFNHQMGETFVLPEAKIQE
CCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHCC
DSKLIPGTNGGKMSKSANNYINIFLDDKALRKQIMSIETDSTPLEAPKNPDTCNAFAIYS
CCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
LMADEAQIAEMRANYLGGNYGYGHAKQAIFELITEKFKTERERYNYYINNLDEVDALLKK
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GAAKASAVADGVLQRVREKLGFGK
CCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]