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The map label for this gene is holB [H]

Identifier: 146298746

GI number: 146298746

Start: 1124337

End: 1125485

Strand: Direct

Name: holB [H]

Synonym: Fjoh_0985

Alternate gene names: 146298746

Gene position: 1124337-1125485 (Clockwise)

Preceding gene: 146298734

Following gene: 146298747

Centisome position: 18.44

GC content: 35.42

Gene sequence:

>1149_bases
ATGCAATTTTCTCAAATTTTAGGTCAGGATTATATCAAAAGCCACTTAATAAAAAGTGCATCTTCCGGACGAATTCCGCA
TGCACAATTATTCATTGGACCCGAAGGAAGCGGTACACTTTCTACTGCAATTGCCTATGCGCAATATATTTTATGCAATA
ATACCGGAAACGAAAATGAAAACGGAAACGACTCCTGTAATTTAAAGTTTCAAAATCTTTCGCATCCCGACCTGCATTTT
ATTTACCCAACAGTTACTACCGAAGATGTAAAAACCAAACCAAAAAGTTTAGACTTTATTCAGGATTGGCGAACATTTAT
TCAGGAAATGCCTTACGGCGGTTTATTTGACTGGTATAAAATTCTGGGCGTTCAAAACAAGCAGGGCGAAATCAGAGTCG
AAGATGCACAGGAAGTTTTAAAGTCACTTTCGCTAAAGTCGTATGAAGGCGGTTATAAAATCATGATTATCTGGATGGCA
GATAAAATGAATATTGCAGCTTCAAACAAACTTTTAAAGCTTCTTGAAGAACCATCAGATAAAACCATTTTTATTCTGAT
TTCTGAAAATGAAGAAGATATTATACAAACCATACGTTCTCGCTGTCAGGTAATTCACTTTAACGGACTTCCGGAAAAAG
TTATTGCCGAAGCATTGGTTTCCAGAGAAAATATCGATTCTAATTTCGCTAAAAAAATCGCTCATCAGGCACAGGGAAAT
TTCAATAAAGCAATGCATTTGTTAAAAGAAGATGATTCTGAATATCCTTTTGAACAGTGGTTTGTCAATTGGGTCCGCGC
TGCTTTTAGAGCAAAAGGAAATGCAGCGGCAATTCAGGATTTAATTTCATGGAGCGAAGAAATTGCTGGACTTGGACGTG
AAAGCCAGAAAAAGTTTATTCAGTTCTGTATCGAAATGTTCAGACAGGCACTTTTACTGAATTATCAAACGCCAAGTTTA
GTTTACATAGAACCAAAAGTCGACAAATTTAAACTCGAAAATTTTGCTCCTTTTGTAAACGGAAATAACATTCACGAAAT
TTTCAAAGAACTTTCAGATGCCATGTATCACATTGAAAGAAACGGAAATGCAAAAATAATCCTAACCGATTTATCTATAA
AACTGACTCGTTTAATTCATAAAAAATAG

Upstream 100 bases:

>100_bases
ATTTTTAGCAAAAATCAATCATAATCTCATAAATCAAATCCAGCCGATAATCTTTTAATCTAAAATTTTTGACTACATCA
TTTTCTTCTATCTTTGCTTC

Downstream 100 bases:

>100_bases
TCCTCAAATGAATAATGTTGCCTCAATTTTATCACTGGCATTTTTAGCCTTAACATTTTTACAATCAGGCTACGAAAAGA
TTTTTTACTGGAAAGATAAT

Product: DNA polymerase III gamma/tau subunits-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFSQILGQDYIKSHLIKSASSGRIPHAQLFIGPEGSGTLSTAIAYAQYILCNNTGNENENGNDSCNLKFQNLSHPDLHF
IYPTVTTEDVKTKPKSLDFIQDWRTFIQEMPYGGLFDWYKILGVQNKQGEIRVEDAQEVLKSLSLKSYEGGYKIMIIWMA
DKMNIAASNKLLKLLEEPSDKTIFILISENEEDIIQTIRSRCQVIHFNGLPEKVIAEALVSRENIDSNFAKKIAHQAQGN
FNKAMHLLKEDDSEYPFEQWFVNWVRAAFRAKGNAAAIQDLISWSEEIAGLGRESQKKFIQFCIEMFRQALLLNYQTPSL
VYIEPKVDKFKLENFAPFVNGNNIHEIFKELSDAMYHIERNGNAKIILTDLSIKLTRLIHKK

Sequences:

>Translated_382_residues
MQFSQILGQDYIKSHLIKSASSGRIPHAQLFIGPEGSGTLSTAIAYAQYILCNNTGNENENGNDSCNLKFQNLSHPDLHF
IYPTVTTEDVKTKPKSLDFIQDWRTFIQEMPYGGLFDWYKILGVQNKQGEIRVEDAQEVLKSLSLKSYEGGYKIMIIWMA
DKMNIAASNKLLKLLEEPSDKTIFILISENEEDIIQTIRSRCQVIHFNGLPEKVIAEALVSRENIDSNFAKKIAHQAQGN
FNKAMHLLKEDDSEYPFEQWFVNWVRAAFRAKGNAAAIQDLISWSEEIAGLGRESQKKFIQFCIEMFRQALLLNYQTPSL
VYIEPKVDKFKLENFAPFVNGNNIHEIFKELSDAMYHIERNGNAKIILTDLSIKLTRLIHKK
>Mature_382_residues
MQFSQILGQDYIKSHLIKSASSGRIPHAQLFIGPEGSGTLSTAIAYAQYILCNNTGNENENGNDSCNLKFQNLSHPDLHF
IYPTVTTEDVKTKPKSLDFIQDWRTFIQEMPYGGLFDWYKILGVQNKQGEIRVEDAQEVLKSLSLKSYEGGYKIMIIWMA
DKMNIAASNKLLKLLEEPSDKTIFILISENEEDIIQTIRSRCQVIHFNGLPEKVIAEALVSRENIDSNFAKKIAHQAQGN
FNKAMHLLKEDDSEYPFEQWFVNWVRAAFRAKGNAAAIQDLISWSEEIAGLGRESQKKFIQFCIEMFRQALLLNYQTPSL
VYIEPKVDKFKLENFAPFVNGNNIHEIFKELSDAMYHIERNGNAKIILTDLSIKLTRLIHKK

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004622 [H]

Pfam domain/function: NA

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43735; Mature: 43735

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSQILGQDYIKSHLIKSASSGRIPHAQLFIGPEGSGTLSTAIAYAQYILCNNTGNENE
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHEECCCCCCCC
NGNDSCNLKFQNLSHPDLHFIYPTVTTEDVKTKPKSLDFIQDWRTFIQEMPYGGLFDWYK
CCCCEEEEEECCCCCCCEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
ILGVQNKQGEIRVEDAQEVLKSLSLKSYEGGYKIMIIWMADKMNIAASNKLLKLLEEPSD
HHCCCCCCCCEEEHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCC
KTIFILISENEEDIIQTIRSRCQVIHFNGLPEKVIAEALVSRENIDSNFAKKIAHQAQGN
CEEEEEEECCHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
FNKAMHLLKEDDSEYPFEQWFVNWVRAAFRAKGNAAAIQDLISWSEEIAGLGRESQKKFI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
QFCIEMFRQALLLNYQTPSLVYIEPKVDKFKLENFAPFVNGNNIHEIFKELSDAMYHIER
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHHEEHCC
NGNAKIILTDLSIKLTRLIHKK
CCCEEEEEEECHHHHHHHHHCC
>Mature Secondary Structure
MQFSQILGQDYIKSHLIKSASSGRIPHAQLFIGPEGSGTLSTAIAYAQYILCNNTGNENE
CCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHEECCCCCCCC
NGNDSCNLKFQNLSHPDLHFIYPTVTTEDVKTKPKSLDFIQDWRTFIQEMPYGGLFDWYK
CCCCEEEEEECCCCCCCEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
ILGVQNKQGEIRVEDAQEVLKSLSLKSYEGGYKIMIIWMADKMNIAASNKLLKLLEEPSD
HHCCCCCCCCEEEHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCC
KTIFILISENEEDIIQTIRSRCQVIHFNGLPEKVIAEALVSRENIDSNFAKKIAHQAQGN
CEEEEEEECCHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
FNKAMHLLKEDDSEYPFEQWFVNWVRAAFRAKGNAAAIQDLISWSEEIAGLGRESQKKFI
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
QFCIEMFRQALLLNYQTPSLVYIEPKVDKFKLENFAPFVNGNNIHEIFKELSDAMYHIER
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHHEEHCC
NGNAKIILTDLSIKLTRLIHKK
CCCEEEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]