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The map label for this gene is 146298707

Identifier: 146298707

GI number: 146298707

Start: 1057685

End: 1058350

Strand: Direct

Name: 146298707

Synonym: Fjoh_0945

Alternate gene names: NA

Gene position: 1057685-1058350 (Clockwise)

Preceding gene: 146298706

Following gene: 146298708

Centisome position: 17.35

GC content: 33.93

Gene sequence:

>666_bases
ATGGCAAACCCAATTCAGATATTATCTACTAAAATACTATCGCCTCTTCATAAACAAGAGTTGGTTAAAATTGGCATCGA
AGTAATCGAAGCTGATTTCATTAAAACAGAAAACAAACCTTTCGAATTAAAAGACCTTAACGAAAGTCTGATTTTCACAA
GTCAAAATGCCGTTCACAGTGTTTTATCAAATCCAAAATCCGAAGAACTTAAAAGCAAAAATGTGTATTGCGTTGGACTT
AAAACCAAAACGCTTTTAAGCGATAATGGCTTTAATGTTGTGGCTTATACAGGTTACGCATCTGATTTGGCAGAAATTAT
CACTTTGATTTATGGAAATGAAAGTTATACTTTTTTCAGCGGCAACTTAAGAAGAGATACTTTGCCAGAAGCTTTGAAAG
AAGCCGGGATAAAACTCAATGAAATTCAGGTTTATGAAACTACACTGCAGCCACAAAAAATAAAAGCAAATCCAGAAGCA
CTTTTGTTTTTTAGTCCATCTGGAGTAAAAAGTTATCTGAAAGACAACACCATAAATAAACAGCTTTGTTTCTGTATTGG
AGAAACCACCGCAGAAGCTTTACATAAAATCACCAAAAACATCATTATCGCAGATCAGCCCACAATTGAAGACGTGATCG
AAGATGTAATTCAAGAATATAAATAG

Upstream 100 bases:

>100_bases
TTTCGGAGTGGAAAAAACTAGGTTTCAACTCAGCTCAGGAAATCTTGAACAATGGCGGAACGGAATTAATGCAAAAGATT
AAAGAATCCCTGAAAAAATA

Downstream 100 bases:

>100_bases
CAATAAGCTTTAGGCAGTAAGCCGTAAGCAAAAAATCATAGTTAAACAAGCTTAAAGCCTAAAGCTTAAAGCCTAAAGCA
AGGAAAAAAATGTTAAAAAA

Product: uroporphyrinogen III synthase HEM4

Products: uroporphyrinogen III; H2O

Alternate protein names: Porphobilinogen Deaminase

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MANPIQILSTKILSPLHKQELVKIGIEVIEADFIKTENKPFELKDLNESLIFTSQNAVHSVLSNPKSEELKSKNVYCVGL
KTKTLLSDNGFNVVAYTGYASDLAEIITLIYGNESYTFFSGNLRRDTLPEALKEAGIKLNEIQVYETTLQPQKIKANPEA
LLFFSPSGVKSYLKDNTINKQLCFCIGETTAEALHKITKNIIIADQPTIEDVIEDVIQEYK

Sequences:

>Translated_221_residues
MANPIQILSTKILSPLHKQELVKIGIEVIEADFIKTENKPFELKDLNESLIFTSQNAVHSVLSNPKSEELKSKNVYCVGL
KTKTLLSDNGFNVVAYTGYASDLAEIITLIYGNESYTFFSGNLRRDTLPEALKEAGIKLNEIQVYETTLQPQKIKANPEA
LLFFSPSGVKSYLKDNTINKQLCFCIGETTAEALHKITKNIIIADQPTIEDVIEDVIQEYK
>Mature_220_residues
ANPIQILSTKILSPLHKQELVKIGIEVIEADFIKTENKPFELKDLNESLIFTSQNAVHSVLSNPKSEELKSKNVYCVGLK
TKTLLSDNGFNVVAYTGYASDLAEIITLIYGNESYTFFSGNLRRDTLPEALKEAGIKLNEIQVYETTLQPQKIKANPEAL
LFFSPSGVKSYLKDNTINKQLCFCIGETTAEALHKITKNIIIADQPTIEDVIEDVIQEYK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4557873, Length=179, Percent_Identity=35.195530726257, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 24731; Mature: 24599

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANPIQILSTKILSPLHKQELVKIGIEVIEADFIKTENKPFELKDLNESLIFTSQNAVHS
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHCCCCCCEEEECHHHHHH
VLSNPKSEELKSKNVYCVGLKTKTLLSDNGFNVVAYTGYASDLAEIITLIYGNESYTFFS
HHCCCCHHHHCCCCEEEEEECEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEE
GNLRRDTLPEALKEAGIKLNEIQVYETTLQPQKIKANPEALLFFSPSGVKSYLKDNTINK
CCCCCCHHHHHHHHHCCEEEEEEEEEECCCCCEECCCCCEEEEECCCHHHHHHHCCCCCH
QLCFCIGETTAEALHKITKNIIIADQPTIEDVIEDVIQEYK
HHEEEECHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ANPIQILSTKILSPLHKQELVKIGIEVIEADFIKTENKPFELKDLNESLIFTSQNAVHS
CCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHCCCCCCEEEECHHHHHH
VLSNPKSEELKSKNVYCVGLKTKTLLSDNGFNVVAYTGYASDLAEIITLIYGNESYTFFS
HHCCCCHHHHCCCCEEEEEECEEEEECCCCCEEEEEECCHHHHHHHHHHHCCCCCEEEEE
GNLRRDTLPEALKEAGIKLNEIQVYETTLQPQKIKANPEALLFFSPSGVKSYLKDNTINK
CCCCCCHHHHHHHHHCCEEEEEEEEEECCCCCEECCCCCEEEEECCCHHHHHHHCCCCCH
QLCFCIGETTAEALHKITKNIIIADQPTIEDVIEDVIQEYK
HHEEEECHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA