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The map label for this gene is mntH [H]

Identifier: 146298694

GI number: 146298694

Start: 1045392

End: 1047260

Strand: Direct

Name: mntH [H]

Synonym: Fjoh_0932

Alternate gene names: 146298694

Gene position: 1045392-1047260 (Clockwise)

Preceding gene: 146298693

Following gene: 146298695

Centisome position: 17.15

GC content: 36.81

Gene sequence:

>1869_bases
ATGACTAAATCTTTAGAAGAAGTAAACCAATCGGTTGCTACAGAACATAAAAAAACAGGATTCAGGAAAATATTAGCCTT
TTTAGGCCCGGCATATTTAGTCAGCGTTGGATATATGGATCCCGGAAACTGGGCAACAGATATTGCAGGCGGAAGCCAGT
TTGGCTATACCCTTGTCTGGGTTTTACTTATGAGTAACTTAATGGCGCTGCTTTTGCAGAGTTTAAGTGCACGTCTTGGA
ATTGTTACGCAGCGTGACCTCGCTCAAGCTTCAAGAGAAACGTATTCAAAATACATTAACTACATTTTATATTTTCTGGC
AGAGATAGCTATTGCCGCCTGCGATTTGGCAGAAGTTCTGGGAATGGCAATTGGAATCAATCTTTTATTTGGAATTCCGC
TTCTTGAGGGTGTTTTAATTACTGTTCTGGATACTTTCCTTCTTTTATTTTTGATTAACAAGGGAATTCGAAAAATGGAA
GCGTTTATAATTGCTTTGGTTGCAATTATTGGGTTTTCATTTATTTTTGAAATGATTTTTGCTGAACCTGAAATTCACAA
GATCATTGGCGGACTTGTGCCTTCTATTCCAAATTCGGCTGCTTTATATATTGCAATCGGAATTATTGGTGCAACGGTAA
TGCCTCATAATCTTTATCTGCATTCTTCTTTGGTGCAAACCAGAAAATTTGACCGAACCCCTGCCGGAATCAAACAAGCT
TTGAAATACAATCTTATTGACTCAACAATTGCTCTTAATCTCGCATTTTTTGTAAATGCTGCGATATTGATTCTGGCTGC
TGCTACTTTTCATAAAAATGGAATGTTTGAGGTTGCCGAAATTCAGGATGCGCATCAGTTTTTAGAGCCTTTACTGGGAA
CTAAATGGGCGCCGATTTTATTTGCCGTTGCCTTAATTGCCGCAGGGCAAAGTTCAACAGTTACAGGAACTTTGGCCGGA
CAAATTGTAATGGAAGGTTATCTCCATTTTAGAATACAGCCATGGGTCCGCAGAATCATTACACGTTTAATTGCTATTGT
TCCGGCCTTAATTGTGATTTACATTTATGGTGAAGATATAACCGGGAAATTATTAATCTTAAGTCAGGTAATTTTGAGCC
TTCAATTGGGATTTGCTATTATTCCGCTGATTCACTTTGTGAGCGACAAATCGAAAATGAATGGTTTTCATATTTCTAAA
ACTACTCAGGTGGTATCGTGGATTATTGCTTCAATCATTGTTTCATTGAATGCAAAATTAGTTTATGACGAAATCACTTC
ATGGCTCGAAACTTCTAATAATCCAGCCTTGTTATGGTTTACTGTTGTTCCGCTGGCTTTTGGATTTTCGGCATTATTGC
TGTATATTATTTTTAAACCGTTTATTGCTAAATTCAAAGCAAAAACGATCAATCATTCTCCGCATAACCTGAAACTTCAT
TTTTCTCAAAAGAAAACTCAGGAAGTTAAAAACATTGCGGTTTCTGTAGATTTTTCTCATGCCGATGAAGCTGCACTTAA
CCATGCCTTCGAGTTGGGCGGAATGGATGCAAAATATACATTAATCCATATTGTTGAAACAGTAGGTGCTTTAGTGTATG
GCACTCATGTTCACGATCATGAAACTACTATCGACGAAAAATTATTATTAGGATACAAAGAAATGCTTTCAGAAAAAGGA
TTCAATATTGAAACTGAACTTGGTTTTGGAAAACCAGCTAAGATAATTCCGGAAATCATAAACAATGGACTTTTCGATAT
TCTGGTAATGGGAACCCACGGCCACACTGGACTAAAAGATATTCTTTTCGGTACAACGGTAGATAAATTGAGACATAAAA
TTTCTATACCTTTGTTGATTGTTAAATAA

Upstream 100 bases:

>100_bases
CAAAATGTTTAAATTCTAACATTTAACTTTTAGGCTCGTCTAAAAATATTGTTCAGCGAATGTAATTTTTACATATATTT
GTTAAAACAATACTTTTACA

Downstream 100 bases:

>100_bases
ACAAGGCTCAAAGGTTCAGAGTTACAAAGGAACAAAGGTTTTCGACTTTGAACCTTTGAACCTTTGCAACTTTGCCCCTC
AAAAAGAAAAAAAATGACCT

Product: Mn2+/Fe2+ transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MTKSLEEVNQSVATEHKKTGFRKILAFLGPAYLVSVGYMDPGNWATDIAGGSQFGYTLVWVLLMSNLMALLLQSLSARLG
IVTQRDLAQASRETYSKYINYILYFLAEIAIAACDLAEVLGMAIGINLLFGIPLLEGVLITVLDTFLLLFLINKGIRKME
AFIIALVAIIGFSFIFEMIFAEPEIHKIIGGLVPSIPNSAALYIAIGIIGATVMPHNLYLHSSLVQTRKFDRTPAGIKQA
LKYNLIDSTIALNLAFFVNAAILILAAATFHKNGMFEVAEIQDAHQFLEPLLGTKWAPILFAVALIAAGQSSTVTGTLAG
QIVMEGYLHFRIQPWVRRIITRLIAIVPALIVIYIYGEDITGKLLILSQVILSLQLGFAIIPLIHFVSDKSKMNGFHISK
TTQVVSWIIASIIVSLNAKLVYDEITSWLETSNNPALLWFTVVPLAFGFSALLLYIIFKPFIAKFKAKTINHSPHNLKLH
FSQKKTQEVKNIAVSVDFSHADEAALNHAFELGGMDAKYTLIHIVETVGALVYGTHVHDHETTIDEKLLLGYKEMLSEKG
FNIETELGFGKPAKIIPEIINNGLFDILVMGTHGHTGLKDILFGTTVDKLRHKISIPLLIVK

Sequences:

>Translated_622_residues
MTKSLEEVNQSVATEHKKTGFRKILAFLGPAYLVSVGYMDPGNWATDIAGGSQFGYTLVWVLLMSNLMALLLQSLSARLG
IVTQRDLAQASRETYSKYINYILYFLAEIAIAACDLAEVLGMAIGINLLFGIPLLEGVLITVLDTFLLLFLINKGIRKME
AFIIALVAIIGFSFIFEMIFAEPEIHKIIGGLVPSIPNSAALYIAIGIIGATVMPHNLYLHSSLVQTRKFDRTPAGIKQA
LKYNLIDSTIALNLAFFVNAAILILAAATFHKNGMFEVAEIQDAHQFLEPLLGTKWAPILFAVALIAAGQSSTVTGTLAG
QIVMEGYLHFRIQPWVRRIITRLIAIVPALIVIYIYGEDITGKLLILSQVILSLQLGFAIIPLIHFVSDKSKMNGFHISK
TTQVVSWIIASIIVSLNAKLVYDEITSWLETSNNPALLWFTVVPLAFGFSALLLYIIFKPFIAKFKAKTINHSPHNLKLH
FSQKKTQEVKNIAVSVDFSHADEAALNHAFELGGMDAKYTLIHIVETVGALVYGTHVHDHETTIDEKLLLGYKEMLSEKG
FNIETELGFGKPAKIIPEIINNGLFDILVMGTHGHTGLKDILFGTTVDKLRHKISIPLLIVK
>Mature_621_residues
TKSLEEVNQSVATEHKKTGFRKILAFLGPAYLVSVGYMDPGNWATDIAGGSQFGYTLVWVLLMSNLMALLLQSLSARLGI
VTQRDLAQASRETYSKYINYILYFLAEIAIAACDLAEVLGMAIGINLLFGIPLLEGVLITVLDTFLLLFLINKGIRKMEA
FIIALVAIIGFSFIFEMIFAEPEIHKIIGGLVPSIPNSAALYIAIGIIGATVMPHNLYLHSSLVQTRKFDRTPAGIKQAL
KYNLIDSTIALNLAFFVNAAILILAAATFHKNGMFEVAEIQDAHQFLEPLLGTKWAPILFAVALIAAGQSSTVTGTLAGQ
IVMEGYLHFRIQPWVRRIITRLIAIVPALIVIYIYGEDITGKLLILSQVILSLQLGFAIIPLIHFVSDKSKMNGFHISKT
TQVVSWIIASIIVSLNAKLVYDEITSWLETSNNPALLWFTVVPLAFGFSALLLYIIFKPFIAKFKAKTINHSPHNLKLHF
SQKKTQEVKNIAVSVDFSHADEAALNHAFELGGMDAKYTLIHIVETVGALVYGTHVHDHETTIDEKLLLGYKEMLSEKGF
NIETELGFGKPAKIIPEIINNGLFDILVMGTHGHTGLKDILFGTTVDKLRHKISIPLLIVK

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=444, Percent_Identity=37.8378378378378, Blast_Score=266, Evalue=4e-71,
Organism=Homo sapiens, GI295293167, Length=436, Percent_Identity=39.2201834862385, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI295293178, Length=436, Percent_Identity=39.2201834862385, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI295293171, Length=436, Percent_Identity=39.2201834862385, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI295293169, Length=436, Percent_Identity=39.2201834862385, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI295293175, Length=436, Percent_Identity=39.2201834862385, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI295293173, Length=436, Percent_Identity=39.2201834862385, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI10835169, Length=436, Percent_Identity=39.2201834862385, Blast_Score=244, Evalue=2e-64,
Organism=Escherichia coli, GI1788736, Length=412, Percent_Identity=41.747572815534, Blast_Score=299, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI193210616, Length=537, Percent_Identity=34.8230912476723, Blast_Score=268, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI17569473, Length=431, Percent_Identity=39.4431554524362, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71999499, Length=449, Percent_Identity=37.1937639198218, Blast_Score=251, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI71993856, Length=231, Percent_Identity=41.1255411255411, Blast_Score=176, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6324450, Length=419, Percent_Identity=37.708830548926, Blast_Score=274, Evalue=3e-74,
Organism=Saccharomyces cerevisiae, GI6323062, Length=395, Percent_Identity=41.0126582278481, Blast_Score=253, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6321841, Length=420, Percent_Identity=39.0476190476191, Blast_Score=245, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24648607, Length=435, Percent_Identity=37.4712643678161, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI281362176, Length=435, Percent_Identity=37.4712643678161, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24648609, Length=435, Percent_Identity=37.4712643678161, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI45553443, Length=410, Percent_Identity=38.780487804878, Blast_Score=256, Evalue=2e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 68551; Mature: 68420

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCHHHHHHHHCCCCEEEEC
>Mature Secondary Structure 
TKSLEEVNQSVATEHKKTGFRKILAFLGPAYLVSVGYMDPGNWATDIAGGSQFGYTLVW
CCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHEECCCCCCCCCCCCCCCCCHHHHHHH
VLLMSNLMALLLQSLSARLGIVTQRDLAQASRETYSKYINYILYFLAEIAIAACDLAEVL
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMAIGINLLFGIPLLEGVLITVLDTFLLLFLINKGIRKMEAFIIALVAIIGFSFIFEMIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEPEIHKIIGGLVPSIPNSAALYIAIGIIGATVMPHNLYLHSSLVQTRKFDRTPAGIKQA
CCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHH
LKYNLIDSTIALNLAFFVNAAILILAAATFHKNGMFEVAEIQDAHQFLEPLLGTKWAPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCHHHHH
FAVALIAAGQSSTVTGTLAGQIVMEGYLHFRIQPWVRRIITRLIAIVPALIVIYIYGEDI
HHHHHHHCCCCCCEEHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHEEEEECCCC
TGKLLILSQVILSLQLGFAIIPLIHFVSDKSKMNGFHISKTTQVVSWIIASIIVSLNAKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEECHHHHHHHHHHHHHHHHHHCCHH
VYDEITSWLETSNNPALLWFTVVPLAFGFSALLLYIIFKPFIAKFKAKTINHSPHNLKLH
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
FSQKKTQEVKNIAVSVDFSHADEAALNHAFELGGMDAKYTLIHIVETVGALVYGTHVHDH
ECHHHHHHHHHEEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
ETTIDEKLLLGYKEMLSEKGFNIETELGFGKPAKIIPEIINNGLFDILVMGTHGHTGLKD
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHH
ILFGTTVDKLRHKISIPLLIVK
HHHHCHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]