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The map label for this gene is aspC [H]

Identifier: 162139460

GI number: 162139460

Start: 3228517

End: 3229713

Strand: Direct

Name: aspC [H]

Synonym: PST_2998

Alternate gene names: 162139460

Gene position: 3228517-3229713 (Clockwise)

Preceding gene: 146283324

Following gene: 146283331

Centisome position: 70.69

GC content: 65.25

Gene sequence:

>1197_bases
ATGAGTTTGTTCTCTGCTGTCGAAATGGCGCCGCGCGATCCTATCCTCGGCCTCAATGAAGCCTTCAACGCCGACACGCG
GCCGAACAAGGTCAACCTCGGTGTCGGTGTCTACTACAACGAAGAAGGTCGCATTCCGCTGCTGCGCGCCGTGGCCGAGG
CCGAGCAGGCACGCATCGCTGCCCATGCGCCGCGCGGCTACCTGCCGATCGAAGGGATCGCCGCCTACGACAACGCGGTG
CAGAAGCTGCTGTTCGGCAATGACGCGGCCCTGATCGCCGAAGGTCGCGTGGTCACGACCCAGGCACTGGGTGGCACCGG
AGCTCTAAAGGTCGGCGCCGACTTCCTCAAGCGTCTGCTGCCCGATGCCGTTGTCGCGATCAGCAACCCGAGCTGGGAAA
ACCACCGCGCGCTGTTCGAATCGGCCGGCTTCCCGGTACAGAGCTACCGCTACTACGATGCCACCAGCCACGGCATCGAC
CGCGCCGGCCTGCTGCAGGACCTCAATGAGCTGCCAGCGCGCTCCATCGTCGTGCTGCATGCCTGCTGCCATAACCCGAC
GGGCGTTGACCTGGACCTGAACGACTGGAAGCAGATCCTCGAGGTGCTGCGCGCCCGGGATCACGTGCCGTTCATCGACA
TCGCCTACCAGGGCTTCGGGGACAGCATCGAGGAAGACGCCGCCGCCGTGCGCCTGTTCGCCGAGTCGGGCATGACCTTC
TTCGTTTCCAGCTCGTTCTCAAAATCCTTCTCGCTGTACGGCGAGCGGGTCGGCGCCCTGTCGATGGTCACCCAGAGCCG
TGACGAGTCGGCGCGCGTGCTGTCGCAGGTCAAGCGGGTGATCCGCACCAACTACTCCAACCCGCCGACCCACGGCGCCA
CCGTGGTCGCCTCCGTGCTCAACAGCCCGGAACTGCGCGCCATGTGGGAAGCCGAGCTGGGCGAGATGCGCAGCCGAATC
CGCGAGATGCGCCTGGGCATGGTCGAGCAACTGGCAGCCAAGGGCGCGAAAGTCGACTTCAGCTTCGTCGCGGCGCAACG
CGGCATGTTCTCCTATTCGGGGCTCACTGCCGAACAGGTCGAGCGCCTGCGGGTCGAGTTCGGTGTCTATGCCATCAGCA
CCGGCCGCATCTGCGCCGCAGCGCTGAACCGCAACAATCTGGGCACCGTCACCGACGCCATCGTCCAGGTGCTCTGA

Upstream 100 bases:

>100_bases
AGGCATGACCGCTATACTACCGCCCCGTTTGCGCATCACCCTGCGCGCCGACGCGAGGGTGGTGAAATCTGTCACTCCTT
CTCTTTCGAGCCCCCTCACC

Downstream 100 bases:

>100_bases
GCCGACGCACCGGGGCCACGGCGCACCTCGCGTCCGGCCCCCGGCGCACTGCTGGAGGGGTTGACTTCTCCTTTCCAAAC
AGTAGGATACGCACCGTTGT

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSLFSAVEMAPRDPILGLNEAFNADTRPNKVNLGVGVYYNEEGRIPLLRAVAEAEQARIAAHAPRGYLPIEGIAAYDNAV
QKLLFGNDAALIAEGRVVTTQALGGTGALKVGADFLKRLLPDAVVAISNPSWENHRALFESAGFPVQSYRYYDATSHGID
RAGLLQDLNELPARSIVVLHACCHNPTGVDLDLNDWKQILEVLRARDHVPFIDIAYQGFGDSIEEDAAAVRLFAESGMTF
FVSSSFSKSFSLYGERVGALSMVTQSRDESARVLSQVKRVIRTNYSNPPTHGATVVASVLNSPELRAMWEAELGEMRSRI
REMRLGMVEQLAAKGAKVDFSFVAAQRGMFSYSGLTAEQVERLRVEFGVYAISTGRICAAALNRNNLGTVTDAIVQVL

Sequences:

>Translated_398_residues
MSLFSAVEMAPRDPILGLNEAFNADTRPNKVNLGVGVYYNEEGRIPLLRAVAEAEQARIAAHAPRGYLPIEGIAAYDNAV
QKLLFGNDAALIAEGRVVTTQALGGTGALKVGADFLKRLLPDAVVAISNPSWENHRALFESAGFPVQSYRYYDATSHGID
RAGLLQDLNELPARSIVVLHACCHNPTGVDLDLNDWKQILEVLRARDHVPFIDIAYQGFGDSIEEDAAAVRLFAESGMTF
FVSSSFSKSFSLYGERVGALSMVTQSRDESARVLSQVKRVIRTNYSNPPTHGATVVASVLNSPELRAMWEAELGEMRSRI
REMRLGMVEQLAAKGAKVDFSFVAAQRGMFSYSGLTAEQVERLRVEFGVYAISTGRICAAALNRNNLGTVTDAIVQVL
>Mature_397_residues
SLFSAVEMAPRDPILGLNEAFNADTRPNKVNLGVGVYYNEEGRIPLLRAVAEAEQARIAAHAPRGYLPIEGIAAYDNAVQ
KLLFGNDAALIAEGRVVTTQALGGTGALKVGADFLKRLLPDAVVAISNPSWENHRALFESAGFPVQSYRYYDATSHGIDR
AGLLQDLNELPARSIVVLHACCHNPTGVDLDLNDWKQILEVLRARDHVPFIDIAYQGFGDSIEEDAAAVRLFAESGMTFF
VSSSFSKSFSLYGERVGALSMVTQSRDESARVLSQVKRVIRTNYSNPPTHGATVVASVLNSPELRAMWEAELGEMRSRIR
EMRLGMVEQLAAKGAKVDFSFVAAQRGMFSYSGLTAEQVERLRVEFGVYAISTGRICAAALNRNNLGTVTDAIVQVL

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=397, Percent_Identity=43.5768261964735, Blast_Score=345, Evalue=5e-95,
Organism=Homo sapiens, GI4504067, Length=402, Percent_Identity=42.2885572139304, Blast_Score=310, Evalue=1e-84,
Organism=Homo sapiens, GI117414139, Length=384, Percent_Identity=29.6875, Blast_Score=181, Evalue=8e-46,
Organism=Escherichia coli, GI1790488, Length=398, Percent_Identity=52.5125628140703, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=48.4848484848485, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71981858, Length=399, Percent_Identity=41.6040100250627, Blast_Score=350, Evalue=8e-97,
Organism=Caenorhabditis elegans, GI25147133, Length=398, Percent_Identity=42.713567839196, Blast_Score=342, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17569539, Length=399, Percent_Identity=39.3483709273183, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17569537, Length=399, Percent_Identity=32.0802005012531, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=41.3145539906103, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17550384, Length=265, Percent_Identity=36.6037735849057, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323055, Length=407, Percent_Identity=36.8550368550369, Blast_Score=293, Evalue=3e-80,
Organism=Saccharomyces cerevisiae, GI6322743, Length=430, Percent_Identity=31.8604651162791, Blast_Score=221, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24580972, Length=399, Percent_Identity=41.8546365914787, Blast_Score=330, Evalue=7e-91,
Organism=Drosophila melanogaster, GI24580970, Length=399, Percent_Identity=41.8546365914787, Blast_Score=330, Evalue=8e-91,
Organism=Drosophila melanogaster, GI19920542, Length=392, Percent_Identity=41.8367346938776, Blast_Score=324, Evalue=7e-89,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=41.1027568922306, Blast_Score=318, Evalue=6e-87,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=41.1027568922306, Blast_Score=318, Evalue=6e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43357; Mature: 43226

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFSAVEMAPRDPILGLNEAFNADTRPNKVNLGVGVYYNEEGRIPLLRAVAEAEQARIA
CCHHHHHHCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AHAPRGYLPIEGIAAYDNAVQKLLFGNDAALIAEGRVVTTQALGGTGALKVGADFLKRLL
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCHHHHHHHHHHHHC
PDAVVAISNPSWENHRALFESAGFPVQSYRYYDATSHGIDRAGLLQDLNELPARSIVVLH
CHHEEEECCCCCHHHHHHHHHCCCCHHHEEEECCCCCCCCHHHHHHHHHHCCCHHEEHHH
ACCHNPTGVDLDLNDWKQILEVLRARDHVPFIDIAYQGFGDSIEEDAAAVRLFAESGMTF
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEE
FVSSSFSKSFSLYGERVGALSMVTQSRDESARVLSQVKRVIRTNYSNPPTHGATVVASVL
EEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NSPELRAMWEAELGEMRSRIREMRLGMVEQLAAKGAKVDFSFVAAQRGMFSYSGLTAEQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHH
ERLRVEFGVYAISTGRICAAALNRNNLGTVTDAIVQVL
HHHHHHHCEEEEECCCEEEEHHCCCCCCHHHHHHHHHC
>Mature Secondary Structure 
SLFSAVEMAPRDPILGLNEAFNADTRPNKVNLGVGVYYNEEGRIPLLRAVAEAEQARIA
CHHHHHHCCCCCCCCCCHHHCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHH
AHAPRGYLPIEGIAAYDNAVQKLLFGNDAALIAEGRVVTTQALGGTGALKVGADFLKRLL
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCEEEEEECCCCCCHHHHHHHHHHHHC
PDAVVAISNPSWENHRALFESAGFPVQSYRYYDATSHGIDRAGLLQDLNELPARSIVVLH
CHHEEEECCCCCHHHHHHHHHCCCCHHHEEEECCCCCCCCHHHHHHHHHHCCCHHEEHHH
ACCHNPTGVDLDLNDWKQILEVLRARDHVPFIDIAYQGFGDSIEEDAAAVRLFAESGMTF
HHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEE
FVSSSFSKSFSLYGERVGALSMVTQSRDESARVLSQVKRVIRTNYSNPPTHGATVVASVL
EEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NSPELRAMWEAELGEMRSRIREMRLGMVEQLAAKGAKVDFSFVAAQRGMFSYSGLTAEQV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHH
ERLRVEFGVYAISTGRICAAALNRNNLGTVTDAIVQVL
HHHHHHHCEEEEECCCEEEEHHCCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]