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The map label for this gene is kefC [C]

Identifier: 146284445

GI number: 146284445

Start: 4487063

End: 4488436

Strand: Direct

Name: kefC [C]

Synonym: PST_4134

Alternate gene names: 146284445

Gene position: 4487063-4488436 (Clockwise)

Preceding gene: 146284444

Following gene: 146284447

Centisome position: 98.24

GC content: 67.47

Gene sequence:

>1374_bases
ATGAATTTTCTCGAATGGATGGCCGTACTCGGCGTCCTGCTGCTGATCCTCGCCCTCGCTTCGGCCTTCCTGCGCTGGCT
GCCAATCACCACGTCCCTGATCTACCTCGGTTTCGGCGTGCTCATCGGCCAGCTCGGCATCGGCCTGTGGGAGATGGAAT
TCCTGCATATCGCCGGCTGGATGGAACACCTCACCGAGGTCGCCGTGCTGGTCTCGCTGTTCGTCAGTGGCCTCAAGCTG
CGTATGCCGCTCAGGCACCCGGCATGGAAGAGCGCCTATGTACTGGCCGGGCCGGTGATGCTCGCCTGCATCGGCGGCGT
CACACTGCTCTGCCACTACCTGTTCGGCCAGAGCTGGGGTGTCGCGGTACTGATCGGGGCGATCCTGGCGCCCACCGATC
CGGTACTGGCGAGCCTGGTGCAGGTCAACGATGCCCGCGACAGCGACCGTCTGCGCTACGGCCTGTCCGGTGAGGCGGGC
TTCAACGACGGCACCGCGTTTCCCTTCGTGGTGTTCGGCCTGATGCTCATCGCCCAAGGCCAGCTGGAGGCCGACTGGGT
CGGCGAATGGGCGCTGCACCGGCTGCTGTGGGCGGTGCCGGCGGGGCTGCTGATCGGCTTTCTGCTGGGCAAGCTGGTCG
GCCGCGTGGCCATCTACCTGCGCGCACGCCACACCGATACCGCCATGTCGCCCAACGACTCGCTGGCCCTGGCGCTGATC
GCCCTGGCCTATGTCGGCGCCGAACTGGCTGGTGCCTGGGGCTTTCTCGCGGTGTTCGCCGCCGGTCTCGGTCTGCGTCA
CGCGGAAATCGCTGCCGCCGGACGCTCCGAGACGCCATCCGAGGAGCTGATCAACGACGCCGTGCCGCACCTCGCCGAAG
GCGGCCTGGCCCCTCGCGCGTTGTCGCTGGATGACCGACAGCTGGGACAACCACGGGTCGCCGCCGGCGTGCTGATGGGT
GACGTACTGGCATTCGGCGGGCAGCTGGAACGCAGCCTGGAAGTGTTGCTGGTGACCATGCTCGGGGTGCTGGTCTCGGT
GCACTGGGACTGGCGTGCAGTGCCACTCGGCCTGGCGCTGTTCCTGCTGATCCGCCCGCTCGCCGTCTGGCTGCTGATGC
CGCGGCGCTACCTGGATCGTGGCCAGTGCCTGACGGTCGGCTGGTTCGGCATCCGCGGCATCCGCGGCATCGGCAGCCTC
TACTACCTGAGCTACGCGGTCACCCACGGGCTGCTGCCGGACGAGACGGAAGTGATCATTTCCCTGGTGATCTCGGTGGT
GGCGCTGAGCATCCTGATCCACGGCCTCAGCACCCAGCCGCTGCTGCGGCGCTACGAACGCAGCCGTGGCCAGGCGCCTA
CCCGCCACGGTTGA

Upstream 100 bases:

>100_bases
GCGGCATCACGCGGCACTGCCGGCGAACCCTGCCGCCGGCCACCGTTCCGATGGCATACACCCCCTGGGCGCAACACCGC
GCCCCGCCATCGGAACACGC

Downstream 100 bases:

>100_bases
GACGGCATCCCGCGCGGCCGACTGGCCAGCCGCGGGTCGCCTGCAGGCAGGTCAGCTGTTGGCGAGGCGGAAGCCGACCT
TCATGGTGACCTGGAAATGC

Product: sodium/hydrogen exchanger family protein

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: Sodium/Hydrogen Exchanger Family Protein; Na+/H+ Antiporter; Transporter CPA2 Family; Cation Transport Related Protein; Na+/H+ Antiporter CPA1 Family Protein; CPA1 Family Na(+)/H(+) Antiporter; NhaP-Type Na+/H+ And K+/H+ Antiporter; Na+/H+ Antiporter-Like Protein; Na(+)/H(+) Antiporter; Cell Volume Regulation Protein A; Sodium/Proton Antiporter CPA1 Family; CPA1 Family Na+/H+ Antiporter; Cation Transporter-Like Protein

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MNFLEWMAVLGVLLLILALASAFLRWLPITTSLIYLGFGVLIGQLGIGLWEMEFLHIAGWMEHLTEVAVLVSLFVSGLKL
RMPLRHPAWKSAYVLAGPVMLACIGGVTLLCHYLFGQSWGVAVLIGAILAPTDPVLASLVQVNDARDSDRLRYGLSGEAG
FNDGTAFPFVVFGLMLIAQGQLEADWVGEWALHRLLWAVPAGLLIGFLLGKLVGRVAIYLRARHTDTAMSPNDSLALALI
ALAYVGAELAGAWGFLAVFAAGLGLRHAEIAAAGRSETPSEELINDAVPHLAEGGLAPRALSLDDRQLGQPRVAAGVLMG
DVLAFGGQLERSLEVLLVTMLGVLVSVHWDWRAVPLGLALFLLIRPLAVWLLMPRRYLDRGQCLTVGWFGIRGIRGIGSL
YYLSYAVTHGLLPDETEVIISLVISVVALSILIHGLSTQPLLRRYERSRGQAPTRHG

Sequences:

>Translated_457_residues
MNFLEWMAVLGVLLLILALASAFLRWLPITTSLIYLGFGVLIGQLGIGLWEMEFLHIAGWMEHLTEVAVLVSLFVSGLKL
RMPLRHPAWKSAYVLAGPVMLACIGGVTLLCHYLFGQSWGVAVLIGAILAPTDPVLASLVQVNDARDSDRLRYGLSGEAG
FNDGTAFPFVVFGLMLIAQGQLEADWVGEWALHRLLWAVPAGLLIGFLLGKLVGRVAIYLRARHTDTAMSPNDSLALALI
ALAYVGAELAGAWGFLAVFAAGLGLRHAEIAAAGRSETPSEELINDAVPHLAEGGLAPRALSLDDRQLGQPRVAAGVLMG
DVLAFGGQLERSLEVLLVTMLGVLVSVHWDWRAVPLGLALFLLIRPLAVWLLMPRRYLDRGQCLTVGWFGIRGIRGIGSL
YYLSYAVTHGLLPDETEVIISLVISVVALSILIHGLSTQPLLRRYERSRGQAPTRHG
>Mature_457_residues
MNFLEWMAVLGVLLLILALASAFLRWLPITTSLIYLGFGVLIGQLGIGLWEMEFLHIAGWMEHLTEVAVLVSLFVSGLKL
RMPLRHPAWKSAYVLAGPVMLACIGGVTLLCHYLFGQSWGVAVLIGAILAPTDPVLASLVQVNDARDSDRLRYGLSGEAG
FNDGTAFPFVVFGLMLIAQGQLEADWVGEWALHRLLWAVPAGLLIGFLLGKLVGRVAIYLRARHTDTAMSPNDSLALALI
ALAYVGAELAGAWGFLAVFAAGLGLRHAEIAAAGRSETPSEELINDAVPHLAEGGLAPRALSLDDRQLGQPRVAAGVLMG
DVLAFGGQLERSLEVLLVTMLGVLVSVHWDWRAVPLGLALFLLIRPLAVWLLMPRRYLDRGQCLTVGWFGIRGIRGIGSL
YYLSYAVTHGLLPDETEVIISLVISVVALSILIHGLSTQPLLRRYERSRGQAPTRHG

Specific function: Transport System That Facilitates Potassium-Efflux, Possibly By Potassium-Proton Antiport. [C]

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49417; Mature: 49417

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFLEWMAVLGVLLLILALASAFLRWLPITTSLIYLGFGVLIGQLGIGLWEMEFLHIAGW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MEHLTEVAVLVSLFVSGLKLRMPLRHPAWKSAYVLAGPVMLACIGGVTLLCHYLFGQSWG
HHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAVLIGAILAPTDPVLASLVQVNDARDSDRLRYGLSGEAGFNDGTAFPFVVFGLMLIAQG
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHEECCCCCCCCCCCCHHHHHHHHHHHHHCC
QLEADWVGEWALHRLLWAVPAGLLIGFLLGKLVGRVAIYLRARHTDTAMSPNDSLALALI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
ALAYVGAELAGAWGFLAVFAAGLGLRHAEIAAAGRSETPSEELINDAVPHLAEGGLAPRA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCE
LSLDDRQLGQPRVAAGVLMGDVLAFGGQLERSLEVLLVTMLGVLVSVHWDWRAVPLGLAL
ECCCHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FLLIRPLAVWLLMPRRYLDRGQCLTVGWFGIRGIRGIGSLYYLSYAVTHGLLPDETEVII
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLVISVVALSILIHGLSTQPLLRRYERSRGQAPTRHG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNFLEWMAVLGVLLLILALASAFLRWLPITTSLIYLGFGVLIGQLGIGLWEMEFLHIAGW
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
MEHLTEVAVLVSLFVSGLKLRMPLRHPAWKSAYVLAGPVMLACIGGVTLLCHYLFGQSWG
HHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAVLIGAILAPTDPVLASLVQVNDARDSDRLRYGLSGEAGFNDGTAFPFVVFGLMLIAQG
HHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHEECCCCCCCCCCCCHHHHHHHHHHHHHCC
QLEADWVGEWALHRLLWAVPAGLLIGFLLGKLVGRVAIYLRARHTDTAMSPNDSLALALI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
ALAYVGAELAGAWGFLAVFAAGLGLRHAEIAAAGRSETPSEELINDAVPHLAEGGLAPRA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCE
LSLDDRQLGQPRVAAGVLMGDVLAFGGQLERSLEVLLVTMLGVLVSVHWDWRAVPLGLAL
ECCCHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
FLLIRPLAVWLLMPRRYLDRGQCLTVGWFGIRGIRGIGSLYYLSYAVTHGLLPDETEVII
HHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
SLVISVVALSILIHGLSTQPLLRRYERSRGQAPTRHG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA