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The map label for this gene is kinB [H]

Identifier: 146284366

GI number: 146284366

Start: 4408096

End: 4409883

Strand: Direct

Name: kinB [H]

Synonym: PST_4054

Alternate gene names: 146284366

Gene position: 4408096-4409883 (Clockwise)

Preceding gene: 146284365

Following gene: 146284367

Centisome position: 96.51

GC content: 66.28

Gene sequence:

>1788_bases
ATGAAACTGCAGATGAAGCTGCGAACCCGACTCTTCCTCGGGTTCTCGGCACTGATGACGGTGGCCCTGCTGGGCCTGCT
GCTGGCGCTGGTCAGCGTGATGCAGATGGCCAAGAGCCAGGAGCAGCTGATCCGCGACAACTTCAGCATCATCGAGATCA
ACCAGCAGCTGCGTCAGACGCTGGGCAATCATCTGATCGTGATGCTTACCGACGACAACCGCAGCGAGGCGCTCGCCCCG
CTGCGCCAGAGCTTCCAGCAGACCCTGGAGCGCGGCATCGCCGAGGCCAACGACGATGTCGACCGCCAGGCCTTCCGTGC
AGTCGCCAGCGCCTATGCCGCCTTCCTGCAGCAGATCGAAGCCAGCCGCCATCAGAACCTGACCCTGCTGGAAGACAACC
CGCTGAGCCAGTCCTTCCACAAGGTCCGCGGCCTGATGACCGACATGCAGGGCGCGGCCTACGACAAGATCCGCGACACC
GAGCTGCGCAGCCGTGATCGCGCCTCGCTGCTGGCGGGCCTGCTGGGACTCACCGCGATAGCCGTGCTGCTGATCGGCTT
CATAACCGCGCACAGCTTCGCGCGACGTTTCGGCGAGCCGATCGAGCGGCTGTCCGCCGCTGCCGACCAGATCGGCCGCG
GTGATTTCAACATCGCCCTGCCGACCCCGCCGATCGCCGAGCTGTCGTCCCTGAGCCGGCGCTTCGGTCTCATGGCGCAG
GCTCTGCACGAGTTCAAGCAGACCAACGTGGAAGCCCTGGTCAACGGTCAGCAGCGCCTGCAGGCGTTGCTCGACAGCAT
CGACGACGGCCTGCTGATCGTCGACCGCGACGGTCGCCTGGAGCACGCCAACCCGGTGGCGCAGCGGCAGCTGGCCTGGG
AGAACGAGCACCTGGGCTCCACCCTTGGCGAAGCGCTGGGCTATCCGCAACTGGACAACGCCGCGCGGCAGGTACTGGAC
GACAAGCCGCTGTCCGACCCGCCAGAGGATCTGGTCATCGAGGCCGACGGCGAACGACGCCTGCTGGCCTGGCGCATCAG
CCCGGTCAGCCACCACGACGGCAGCATCAGTGGCGCGGTGATGGTGCTGCACGACGTCACCGACCAGCGCACCTTCGAAC
GCGTGCGCAACGAATTCGTGCTGCGCGCCTCCCACGAACTGCGCACCCCGGTCACCGGCATGCAGATGGCCTTCAGCCTG
TTGCGCGAGCGCCTGCGCTACCCCGCCGACAGTCGCGAATCCGACCTGTTCGATACGGTCCACGAGGAAATGCAGCGCCT
GGTCAGGCTGATCAACGACCTGCTCAATTTCTCCCGCTACCAAAGCGGCCAGCAGAAACTGGAGCTGGAGCAGTGCGACG
TGCCGGAGCTGCTCGAAGCCGCGCGCCAGCGCTTCGAGGTCAACGCCGCCGAGCAGGACGTGCAGCTCAAGCTGGAGCTG
CAGCAGCCGCTGCCAACGCTGATGCTCGACCGCCAGCAGATCGAGCGGGTGCTGGACAACCTGCTGAGCAACGCCCTGCG
CCACACGCCCAGGGGCGGCGAGGTGCGCCTGCTGGCGCGGCACCATGGCGAGCGGCTGATCCTCAGCGTCGAGGACAACG
GCGAAGGCATTCCCTACAGCCAGCAGGCACGCATCTTCGAACCCTTCGTGCAGATCGGTCGCCGTCGCGGCGGGGCCGGA
CTGGGGCTTGCCTTATGCAAGGAAATTGCCCAGCTGCATGGTGGCCGCATTGGCGTGCACTCGCGGATCGGCCACGGCAC
TATCTTCTACGTGGCGCTGCCGATCTGA

Upstream 100 bases:

>100_bases
TCGCCGGCGTGCTGAGCACCAGCGACACACTGGAGCAGGCCGCACGCATCCTCGGCATCGACGCCTCGACCCTGTACAGA
AAGCGCAAGCAGTACGGCCT

Downstream 100 bases:

>100_bases
CGGCGCCCCATCGAGGAACCTGCCATGCCGAGTCTGAACCCCAGCCCCGAGCAGCTCGCCGACTATGTGGCGGCGATGCC
CTCGGGCGTGCCGATCCTGA

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MKLQMKLRTRLFLGFSALMTVALLGLLLALVSVMQMAKSQEQLIRDNFSIIEINQQLRQTLGNHLIVMLTDDNRSEALAP
LRQSFQQTLERGIAEANDDVDRQAFRAVASAYAAFLQQIEASRHQNLTLLEDNPLSQSFHKVRGLMTDMQGAAYDKIRDT
ELRSRDRASLLAGLLGLTAIAVLLIGFITAHSFARRFGEPIERLSAAADQIGRGDFNIALPTPPIAELSSLSRRFGLMAQ
ALHEFKQTNVEALVNGQQRLQALLDSIDDGLLIVDRDGRLEHANPVAQRQLAWENEHLGSTLGEALGYPQLDNAARQVLD
DKPLSDPPEDLVIEADGERRLLAWRISPVSHHDGSISGAVMVLHDVTDQRTFERVRNEFVLRASHELRTPVTGMQMAFSL
LRERLRYPADSRESDLFDTVHEEMQRLVRLINDLLNFSRYQSGQQKLELEQCDVPELLEAARQRFEVNAAEQDVQLKLEL
QQPLPTLMLDRQQIERVLDNLLSNALRHTPRGGEVRLLARHHGERLILSVEDNGEGIPYSQQARIFEPFVQIGRRRGGAG
LGLALCKEIAQLHGGRIGVHSRIGHGTIFYVALPI

Sequences:

>Translated_595_residues
MKLQMKLRTRLFLGFSALMTVALLGLLLALVSVMQMAKSQEQLIRDNFSIIEINQQLRQTLGNHLIVMLTDDNRSEALAP
LRQSFQQTLERGIAEANDDVDRQAFRAVASAYAAFLQQIEASRHQNLTLLEDNPLSQSFHKVRGLMTDMQGAAYDKIRDT
ELRSRDRASLLAGLLGLTAIAVLLIGFITAHSFARRFGEPIERLSAAADQIGRGDFNIALPTPPIAELSSLSRRFGLMAQ
ALHEFKQTNVEALVNGQQRLQALLDSIDDGLLIVDRDGRLEHANPVAQRQLAWENEHLGSTLGEALGYPQLDNAARQVLD
DKPLSDPPEDLVIEADGERRLLAWRISPVSHHDGSISGAVMVLHDVTDQRTFERVRNEFVLRASHELRTPVTGMQMAFSL
LRERLRYPADSRESDLFDTVHEEMQRLVRLINDLLNFSRYQSGQQKLELEQCDVPELLEAARQRFEVNAAEQDVQLKLEL
QQPLPTLMLDRQQIERVLDNLLSNALRHTPRGGEVRLLARHHGERLILSVEDNGEGIPYSQQARIFEPFVQIGRRRGGAG
LGLALCKEIAQLHGGRIGVHSRIGHGTIFYVALPI
>Mature_595_residues
MKLQMKLRTRLFLGFSALMTVALLGLLLALVSVMQMAKSQEQLIRDNFSIIEINQQLRQTLGNHLIVMLTDDNRSEALAP
LRQSFQQTLERGIAEANDDVDRQAFRAVASAYAAFLQQIEASRHQNLTLLEDNPLSQSFHKVRGLMTDMQGAAYDKIRDT
ELRSRDRASLLAGLLGLTAIAVLLIGFITAHSFARRFGEPIERLSAAADQIGRGDFNIALPTPPIAELSSLSRRFGLMAQ
ALHEFKQTNVEALVNGQQRLQALLDSIDDGLLIVDRDGRLEHANPVAQRQLAWENEHLGSTLGEALGYPQLDNAARQVLD
DKPLSDPPEDLVIEADGERRLLAWRISPVSHHDGSISGAVMVLHDVTDQRTFERVRNEFVLRASHELRTPVTGMQMAFSL
LRERLRYPADSRESDLFDTVHEEMQRLVRLINDLLNFSRYQSGQQKLELEQCDVPELLEAARQRFEVNAAEQDVQLKLEL
QQPLPTLMLDRQQIERVLDNLLSNALRHTPRGGEVRLLARHHGERLILSVEDNGEGIPYSQQARIFEPFVQIGRRRGGAG
LGLALCKEIAQLHGGRIGVHSRIGHGTIFYVALPI

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=383, Percent_Identity=29.7650130548303, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1788549, Length=549, Percent_Identity=25.8652094717668, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87081816, Length=225, Percent_Identity=32.8888888888889, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1786912, Length=224, Percent_Identity=33.9285714285714, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI145693157, Length=225, Percent_Identity=31.5555555555556, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=30, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788713, Length=229, Percent_Identity=29.2576419213974, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI48994928, Length=272, Percent_Identity=26.8382352941176, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1787894, Length=219, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=29.4372294372294, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790436, Length=212, Percent_Identity=29.7169811320755, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=29.3859649122807, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790300, Length=359, Percent_Identity=30.6406685236769, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=33.7837837837838, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=205, Percent_Identity=30.7317073170732, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=29.1845493562232, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1788279, Length=227, Percent_Identity=25.1101321585903, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=253, Percent_Identity=26.4822134387352, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789808, Length=218, Percent_Identity=27.9816513761468, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66790; Mature: 66790

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQMKLRTRLFLGFSALMTVALLGLLLALVSVMQMAKSQEQLIRDNFSIIEINQQLRQT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
LGNHLIVMLTDDNRSEALAPLRQSFQQTLERGIAEANDDVDRQAFRAVASAYAAFLQQIE
HCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ASRHQNLTLLEDNPLSQSFHKVRGLMTDMQGAAYDKIRDTELRSRDRASLLAGLLGLTAI
HHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLLIGFITAHSFARRFGEPIERLSAAADQIGRGDFNIALPTPPIAELSSLSRRFGLMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
ALHEFKQTNVEALVNGQQRLQALLDSIDDGLLIVDRDGRLEHANPVAQRQLAWENEHLGS
HHHHHHHCCHHHHHCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCHHHHHH
TLGEALGYPQLDNAARQVLDDKPLSDPPEDLVIEADGERRLLAWRISPVSHHDGSISGAV
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCE
MVLHDVTDQRTFERVRNEFVLRASHELRTPVTGMQMAFSLLRERLRYPADSRESDLFDTV
EEEEHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
HEEMQRLVRLINDLLNFSRYQSGQQKLELEQCDVPELLEAARQRFEVNAAEQDVQLKLEL
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEE
QQPLPTLMLDRQQIERVLDNLLSNALRHTPRGGEVRLLARHHGERLILSVEDNGEGIPYS
CCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCC
QQARIFEPFVQIGRRRGGAGLGLALCKEIAQLHGGRIGVHSRIGHGTIFYVALPI
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEECC
>Mature Secondary Structure
MKLQMKLRTRLFLGFSALMTVALLGLLLALVSVMQMAKSQEQLIRDNFSIIEINQQLRQT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHH
LGNHLIVMLTDDNRSEALAPLRQSFQQTLERGIAEANDDVDRQAFRAVASAYAAFLQQIE
HCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
ASRHQNLTLLEDNPLSQSFHKVRGLMTDMQGAAYDKIRDTELRSRDRASLLAGLLGLTAI
HHHCCCCEEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLLIGFITAHSFARRFGEPIERLSAAADQIGRGDFNIALPTPPIAELSSLSRRFGLMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHH
ALHEFKQTNVEALVNGQQRLQALLDSIDDGLLIVDRDGRLEHANPVAQRQLAWENEHLGS
HHHHHHHCCHHHHHCHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCHHHHHH
TLGEALGYPQLDNAARQVLDDKPLSDPPEDLVIEADGERRLLAWRISPVSHHDGSISGAV
HHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCE
MVLHDVTDQRTFERVRNEFVLRASHELRTPVTGMQMAFSLLRERLRYPADSRESDLFDTV
EEEEHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
HEEMQRLVRLINDLLNFSRYQSGQQKLELEQCDVPELLEAARQRFEVNAAEQDVQLKLEL
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEE
QQPLPTLMLDRQQIERVLDNLLSNALRHTPRGGEVRLLARHHGERLILSVEDNGEGIPYS
CCCCHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCC
QQARIFEPFVQIGRRRGGAGLGLALCKEIAQLHGGRIGVHSRIGHGTIFYVALPI
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEECCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]