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The map label for this gene is tctD [H]

Identifier: 146284354

GI number: 146284354

Start: 4391336

End: 4392151

Strand: Direct

Name: tctD [H]

Synonym: PST_4042

Alternate gene names: 146284354

Gene position: 4391336-4392151 (Clockwise)

Preceding gene: 146284348

Following gene: 146284355

Centisome position: 96.14

GC content: 68.75

Gene sequence:

>816_bases
ATGCGCCGCGCAAGGTGGATCGAGCCACCTGTAAGCGATCCTATGGGGTCAAGCTTTCGCCAGCCTTTCAGCGTCGAAAG
CCTGCGGCGACTCTTGCCGTCTGCCGCTACACTGGCGCCCCGTCGCAATGGCAGAGGACAGGCAATGCGGATTCTTCTGG
TCGAGGATCACCCCCAGCTGGCCGAGAGCGTGGCGCAGGCGCTGCGCGGCGCCGGCTGGACCGTGGACCTGCTGCACGAC
GGCATCGCCGCCGACCTGGCGCTGGCCAGCGAGGACTATGCGCTGGCGATTCTCGACGTCGGGCTGCCGCGGCTGGATGG
CTTTCAGGTGCTGGCGCGCCTGCGCGGGCGCGGCAAGACGCTGCCGGTGCTGATGCTCACCGCGCGAGGTGAGGTCAGCG
ATCGCGTGCACGGGCTCAACCTCGGTGCCGACGACTACCTGGCCAAGCCGTTCGAGCTGTCCGAGCTGGAAGCGCGGGTC
AAGGCGCTGCTGCGACGCAGCGTCGGCGGCGGCGAGCGCCAGCAGCGCTGCGGTGTACTGGTCTACGACCTGGATGCGCG
GCGCTTCAGCCTGGCCGACGAGCCGCTGACGCTGACCTCCCGGGAACAGAGCGTGCTCGAGGCACTGATCGCCCGTCCCG
GCCGGGTGATGAGCAAGGATCAGCTGGCCGCCCAGGTGTTCGGCCTGGACGAGGACGCCAGCGCCGACGCCATCGAGATC
TATGTCTACCGGCTGCGCAAGAAGCTCGAGGGCCAACCGGTGCGCATCGTCACCTTCCGCGGCCTGGGCTACATGCTCGA
GGCGCTCGATGGCTGA

Upstream 100 bases:

>100_bases
GGCGGCGGCAACGGCGAGAGCGAGACGAGCAGGAGCGGGTGAGCGTCTGACGGCAGTCAGCATCGGGGTATCTCCACTAT
TGTTTTTGTTGTGACGGCGC

Downstream 100 bases:

>100_bases
GCCGGAGGTCGCCGGCAGCCTGCGTGCCCGGCTGCTGCGCCGGCTGGCGATCCTGCTCGCGCTGCTGCTGCTGTTCAGCG
GCTGGAGTGCCTACTGGAAC

Product: transcriptional regulatory protein TctD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRRARWIEPPVSDPMGSSFRQPFSVESLRRLLPSAATLAPRRNGRGQAMRILLVEDHPQLAESVAQALRGAGWTVDLLHD
GIAADLALASEDYALAILDVGLPRLDGFQVLARLRGRGKTLPVLMLTARGEVSDRVHGLNLGADDYLAKPFELSELEARV
KALLRRSVGGGERQQRCGVLVYDLDARRFSLADEPLTLTSREQSVLEALIARPGRVMSKDQLAAQVFGLDEDASADAIEI
YVYRLRKKLEGQPVRIVTFRGLGYMLEALDG

Sequences:

>Translated_271_residues
MRRARWIEPPVSDPMGSSFRQPFSVESLRRLLPSAATLAPRRNGRGQAMRILLVEDHPQLAESVAQALRGAGWTVDLLHD
GIAADLALASEDYALAILDVGLPRLDGFQVLARLRGRGKTLPVLMLTARGEVSDRVHGLNLGADDYLAKPFELSELEARV
KALLRRSVGGGERQQRCGVLVYDLDARRFSLADEPLTLTSREQSVLEALIARPGRVMSKDQLAAQVFGLDEDASADAIEI
YVYRLRKKLEGQPVRIVTFRGLGYMLEALDG
>Mature_271_residues
MRRARWIEPPVSDPMGSSFRQPFSVESLRRLLPSAATLAPRRNGRGQAMRILLVEDHPQLAESVAQALRGAGWTVDLLHD
GIAADLALASEDYALAILDVGLPRLDGFQVLARLRGRGKTLPVLMLTARGEVSDRVHGLNLGADDYLAKPFELSELEARV
KALLRRSVGGGERQQRCGVLVYDLDARRFSLADEPLTLTSREQSVLEALIARPGRVMSKDQLAAQVFGLDEDASADAIEI
YVYRLRKKLEGQPVRIVTFRGLGYMLEALDG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=40.7079646017699, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=41.2844036697248, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=39.0909090909091, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=38.4615384615385, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=38.5650224215247, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=35.2173913043478, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=36.0869565217391, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=37.3873873873874, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=35.5855855855856, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=36.6812227074236, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=34.375, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.858407079646, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=28.695652173913, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788713, Length=117, Percent_Identity=32.4786324786325, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=25.1082251082251, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=30.952380952381, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI145693157, Length=105, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=147, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29852; Mature: 29852

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRARWIEPPVSDPMGSSFRQPFSVESLRRLLPSAATLAPRRNGRGQAMRILLVEDHPQL
CCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHCCHHHHHCCCCCCCCCEEEEEEECCCHHH
AESVAQALRGAGWTVDLLHDGIAADLALASEDYALAILDVGLPRLDGFQVLARLRGRGKT
HHHHHHHHHCCCCEEEHHHCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCC
LPVLMLTARGEVSDRVHGLNLGADDYLAKPFELSELEARVKALLRRSVGGGERQQRCGVL
CEEEEEECCCCHHHCEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCEE
VYDLDARRFSLADEPLTLTSREQSVLEALIARPGRVMSKDQLAAQVFGLDEDASADAIEI
EEECCCCEEECCCCCEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHH
YVYRLRKKLEGQPVRIVTFRGLGYMLEALDG
HHHHHHHHHCCCCEEEEEECCHHHHHHHHCC
>Mature Secondary Structure
MRRARWIEPPVSDPMGSSFRQPFSVESLRRLLPSAATLAPRRNGRGQAMRILLVEDHPQL
CCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHCCHHHHHCCCCCCCCCEEEEEEECCCHHH
AESVAQALRGAGWTVDLLHDGIAADLALASEDYALAILDVGLPRLDGFQVLARLRGRGKT
HHHHHHHHHCCCCEEEHHHCCHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCC
LPVLMLTARGEVSDRVHGLNLGADDYLAKPFELSELEARVKALLRRSVGGGERQQRCGVL
CEEEEEECCCCHHHCEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCEE
VYDLDARRFSLADEPLTLTSREQSVLEALIARPGRVMSKDQLAAQVFGLDEDASADAIEI
EEECCCCEEECCCCCEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHH
YVYRLRKKLEGQPVRIVTFRGLGYMLEALDG
HHHHHHHHHCCCCEEEEEECCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]