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The map label for this gene is iolS [H]

Identifier: 146284133

GI number: 146284133

Start: 4133472

End: 4134281

Strand: Direct

Name: iolS [H]

Synonym: PST_3821

Alternate gene names: 146284133

Gene position: 4133472-4134281 (Clockwise)

Preceding gene: 146284132

Following gene: 146284134

Centisome position: 90.5

GC content: 65.43

Gene sequence:

>810_bases
ATGAACGCGACGCTGCATGACCTGCACCGCCCGCTGGGCAAAACCGGCCTGCGCATTTCGCCGTTGGGTCTGGGCACGGT
CAAACTGGGTCGCGACCAGGGCGTGAAGTACCCCAACGGCTTCGCCATCCCCGACGATGACCAGGCCCGCCAGCTGCTGA
CCCTCGCCCGCGAACTGGGTATCAACCTGATCGACACCGCGCCGGCCTACGGCGTCAGCGAGGAACGGCTCGGCCCGTTG
CTGGCCGGACAGCGCGAGGATTGGGTGATCGTCAGCAAGGTTGGCGAGGAGTTCGAGAACGGCCAGTCACGCTTCGATTT
TTCCGCCGCGCACACGCGCTTCTCGGTGGAGCGCAGCCTCCAGCGCCTGCGTACCGACCGCATCGAGCTGGTGCTGGTGC
ACTCGGACGGCAACGACCTCGACATCCTGCAGCACACCGAGGTCTACCAGACCCTGGCCGAGCTCAAGCGCGAGGGCAAG
ATCCTCGCCTTCGGCCTGTCCGGCAAGACGGTCGATGGTGGGCTGCTTGCGCTGCAGCAGGGCGACTGCGCGATGGTGAC
CTACAACCTCAACGAGCAGGCCGAACGACCGGTCCTCGACTACGCTGCTGCACACGGCAAGGGCATCCTGATCAAGAAAG
CCCTGGCCAGCGGACATGCCTGCCTCAAGCCAGGCGACGACCCGGTCCGCCGCAGTTTCGAGCTGCTGTTCGGTCACCCA
GGGGTCAGCGGCGCGATCATCGGCACTATCAATCCGCAGCATTTGACGTCTAACGTAGCCACTGCTGCCGCCGTCCTGAC
GGGCGATTGA

Upstream 100 bases:

>100_bases
CCGCCCTCGCCCGTGACGGCATTCGCCCGGCCAACCATCCCGCACTACCTCAACTGCCACGTCCGCCGCTGACCGGGCCG
TTCTGGGAAGGGCTGCTGCC

Downstream 100 bases:

>100_bases
CCTCGGAGGCGCAGCGTTCCGTTCGCTGCGCGGCAGCAGCCACCGGCGCCGCGCAGCGGCCCCGTTCGCCGTAAGGAGAG
CCCGAATGCCTCGCGTTCTG

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNATLHDLHRPLGKTGLRISPLGLGTVKLGRDQGVKYPNGFAIPDDDQARQLLTLARELGINLIDTAPAYGVSEERLGPL
LAGQREDWVIVSKVGEEFENGQSRFDFSAAHTRFSVERSLQRLRTDRIELVLVHSDGNDLDILQHTEVYQTLAELKREGK
ILAFGLSGKTVDGGLLALQQGDCAMVTYNLNEQAERPVLDYAAAHGKGILIKKALASGHACLKPGDDPVRRSFELLFGHP
GVSGAIIGTINPQHLTSNVATAAAVLTGD

Sequences:

>Translated_269_residues
MNATLHDLHRPLGKTGLRISPLGLGTVKLGRDQGVKYPNGFAIPDDDQARQLLTLARELGINLIDTAPAYGVSEERLGPL
LAGQREDWVIVSKVGEEFENGQSRFDFSAAHTRFSVERSLQRLRTDRIELVLVHSDGNDLDILQHTEVYQTLAELKREGK
ILAFGLSGKTVDGGLLALQQGDCAMVTYNLNEQAERPVLDYAAAHGKGILIKKALASGHACLKPGDDPVRRSFELLFGHP
GVSGAIIGTINPQHLTSNVATAAAVLTGD
>Mature_269_residues
MNATLHDLHRPLGKTGLRISPLGLGTVKLGRDQGVKYPNGFAIPDDDQARQLLTLARELGINLIDTAPAYGVSEERLGPL
LAGQREDWVIVSKVGEEFENGQSRFDFSAAHTRFSVERSLQRLRTDRIELVLVHSDGNDLDILQHTEVYQTLAELKREGK
ILAFGLSGKTVDGGLLALQQGDCAMVTYNLNEQAERPVLDYAAAHGKGILIKKALASGHACLKPGDDPVRRSFELLFGHP
GVSGAIIGTINPQHLTSNVATAAAVLTGD

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788070, Length=209, Percent_Identity=33.9712918660287, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081735, Length=236, Percent_Identity=30.0847457627119, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323684, Length=162, Percent_Identity=35.1851851851852, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24646155, Length=221, Percent_Identity=33.4841628959276, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646159, Length=171, Percent_Identity=35.672514619883, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29030; Mature: 29030

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATLHDLHRPLGKTGLRISPLGLGTVKLGRDQGVKYPNGFAIPDDDQARQLLTLARELG
CCCCHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
INLIDTAPAYGVSEERLGPLLAGQREDWVIVSKVGEEFENGQSRFDFSAAHTRFSVERSL
CEEEECCCCCCCCHHHCCHHHCCCCCCEEEEEHHHHHHHCCCCCEEHHHHHHHHHHHHHH
QRLRTDRIELVLVHSDGNDLDILQHTEVYQTLAELKREGKILAFGLSGKTVDGGLLALQQ
HHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCEEEEEC
GDCAMVTYNLNEQAERPVLDYAAAHGKGILIKKALASGHACLKPGDDPVRRSFELLFGHP
CCEEEEEEECCCCCCCCHHHHHHHCCCEEEEEEHHHCCCEECCCCCHHHHHHHHHEECCC
GVSGAIIGTINPQHLTSNVATAAAVLTGD
CCCCEEEECCCHHHHHHHHHHEEEEEECC
>Mature Secondary Structure
MNATLHDLHRPLGKTGLRISPLGLGTVKLGRDQGVKYPNGFAIPDDDQARQLLTLARELG
CCCCHHHHHHHHCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
INLIDTAPAYGVSEERLGPLLAGQREDWVIVSKVGEEFENGQSRFDFSAAHTRFSVERSL
CEEEECCCCCCCCHHHCCHHHCCCCCCEEEEEHHHHHHHCCCCCEEHHHHHHHHHHHHHH
QRLRTDRIELVLVHSDGNDLDILQHTEVYQTLAELKREGKILAFGLSGKTVDGGLLALQQ
HHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEECCCEEEEEC
GDCAMVTYNLNEQAERPVLDYAAAHGKGILIKKALASGHACLKPGDDPVRRSFELLFGHP
CCEEEEEEECCCCCCCCHHHHHHHCCCEEEEEEHHHCCCEECCCCCHHHHHHHHHEECCC
GVSGAIIGTINPQHLTSNVATAAAVLTGD
CCCCEEEECCCHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]