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The map label for this gene is fieF [H]

Identifier: 146284027

GI number: 146284027

Start: 4016171

End: 4017061

Strand: Direct

Name: fieF [H]

Synonym: PST_3715

Alternate gene names: 146284027

Gene position: 4016171-4017061 (Clockwise)

Preceding gene: 146284026

Following gene: 146284028

Centisome position: 87.93

GC content: 66.22

Gene sequence:

>891_bases
ATGAGCATCAATCGCGACCACGCCCGGCTCATGCGCCGGGCCACCGCCGCGGCATTGGCGACGGCCATCCTGCTGGCGCT
GAGCAAGGCCGTCGCCTGGTGGCTGAGCGGCTCGGTGAGCCTGCTGGCCGGCCTCACCGACTCGCTGCTGGACGGCGCCG
CCTCGCTGCTCAACCTGCTGGCGGTGCACTACTCGCTGCGCCCGGCGGACGACGATCACCGCTACGGCCATGGCAAGGCC
GAGGCACTGGCCGGGCTGGGGCAGGCGGCATTCATCTGCGTCAGCGCGATCCTCGTCGGCGTGCAAGGCGTCGACCGCCT
GCTGCATCCGCAACCGTTGGGCGCGCAGGGTGTAGGCATCGCGGTGATGATCTTCTCGCTGGTGATGACCGCCGTGCTGC
TGACCTACCAGCATCACGTGGTGAAAATCACCGGTTCCACCGCCGTTCGCGCCGATTCGCTGCACTACCGCTCCGACCTG
CTGCTCAACAGCAGCATCCTGCTCGCGCTGGTCCTCGCCAGCTTTGGCTGGGAGCGTACCGACGCGTTGTTCGGCATCGC
CATCGCCTTTTACATCTTCTGGAGCGCGATCAGCATCGTCCGCGAGGCCGGGGCCGTGCTGATGGATACCGAGCTGTCGC
CGGAGATCAGCGAACAGATGCAGCAACTGGTCTGCGAAGTGCCCGGGGTACATGGTTGCCATGACTTCCGCACGCGGGTT
TCCGGCACGCGCTGGTTCGTCCAGTTGCACCTGGAACTGCCTGGTGAACTGCCGCTGTCGCAGGCACATGATCTGTGTGT
GGCGGTGGAGAATGCGATTCATGACCGCTATCCGAACGCGGAGGTGCTGGTGCATGCCGACCCGCTTGAGGTAGCGCCGC
CGAGGCGGTGA

Upstream 100 bases:

>100_bases
GACGACCCGCGACTGATCCAGCACAACGGCAGCGTCGAGCAGCTGGCCGCCTTCGGCCTGCGCCCGGCCGCTTGATGCCC
ACGAGGGACAGCCGCCGCCG

Downstream 100 bases:

>100_bases
GCCTTCGACCAGTGTCAGGCGTCGGGGCGATAGAGCCCCTGTCTGTATCGCTTGCAGGTTTGCAGACCTTGCATCGCCGA
TCACATCCAAACCCCCACGA

Product: cation efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSINRDHARLMRRATAAALATAILLALSKAVAWWLSGSVSLLAGLTDSLLDGAASLLNLLAVHYSLRPADDDHRYGHGKA
EALAGLGQAAFICVSAILVGVQGVDRLLHPQPLGAQGVGIAVMIFSLVMTAVLLTYQHHVVKITGSTAVRADSLHYRSDL
LLNSSILLALVLASFGWERTDALFGIAIAFYIFWSAISIVREAGAVLMDTELSPEISEQMQQLVCEVPGVHGCHDFRTRV
SGTRWFVQLHLELPGELPLSQAHDLCVAVENAIHDRYPNAEVLVHADPLEVAPPRR

Sequences:

>Translated_296_residues
MSINRDHARLMRRATAAALATAILLALSKAVAWWLSGSVSLLAGLTDSLLDGAASLLNLLAVHYSLRPADDDHRYGHGKA
EALAGLGQAAFICVSAILVGVQGVDRLLHPQPLGAQGVGIAVMIFSLVMTAVLLTYQHHVVKITGSTAVRADSLHYRSDL
LLNSSILLALVLASFGWERTDALFGIAIAFYIFWSAISIVREAGAVLMDTELSPEISEQMQQLVCEVPGVHGCHDFRTRV
SGTRWFVQLHLELPGELPLSQAHDLCVAVENAIHDRYPNAEVLVHADPLEVAPPRR
>Mature_295_residues
SINRDHARLMRRATAAALATAILLALSKAVAWWLSGSVSLLAGLTDSLLDGAASLLNLLAVHYSLRPADDDHRYGHGKAE
ALAGLGQAAFICVSAILVGVQGVDRLLHPQPLGAQGVGIAVMIFSLVMTAVLLTYQHHVVKITGSTAVRADSLHYRSDLL
LNSSILLALVLASFGWERTDALFGIAIAFYIFWSAISIVREAGAVLMDTELSPEISEQMQQLVCEVPGVHGCHDFRTRVS
GTRWFVQLHLELPGELPLSQAHDLCVAVENAIHDRYPNAEVLVHADPLEVAPPRR

Specific function: Cation-efflux transporter that may have a role in detoxification [H]

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790349, Length=291, Percent_Identity=49.1408934707904, Blast_Score=271, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 31939; Mature: 31808

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINRDHARLMRRATAAALATAILLALSKAVAWWLSGSVSLLAGLTDSLLDGAASLLNLL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AVHYSLRPADDDHRYGHGKAEALAGLGQAAFICVSAILVGVQGVDRLLHPQPLGAQGVGI
HHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
AVMIFSLVMTAVLLTYQHHVVKITGSTAVRADSLHYRSDLLLNSSILLALVLASFGWERT
HHHHHHHHHHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
DALFGIAIAFYIFWSAISIVREAGAVLMDTELSPEISEQMQQLVCEVPGVHGCHDFRTRV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHC
SGTRWFVQLHLELPGELPLSQAHDLCVAVENAIHDRYPNAEVLVHADPLEVAPPRR
CCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
SINRDHARLMRRATAAALATAILLALSKAVAWWLSGSVSLLAGLTDSLLDGAASLLNLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AVHYSLRPADDDHRYGHGKAEALAGLGQAAFICVSAILVGVQGVDRLLHPQPLGAQGVGI
HHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
AVMIFSLVMTAVLLTYQHHVVKITGSTAVRADSLHYRSDLLLNSSILLALVLASFGWERT
HHHHHHHHHHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHH
DALFGIAIAFYIFWSAISIVREAGAVLMDTELSPEISEQMQQLVCEVPGVHGCHDFRTRV
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHHHC
SGTRWFVQLHLELPGELPLSQAHDLCVAVENAIHDRYPNAEVLVHADPLEVAPPRR
CCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA