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The map label for this gene is czcB [H]

Identifier: 146283741

GI number: 146283741

Start: 3698472

End: 3699779

Strand: Direct

Name: czcB [H]

Synonym: PST_3424

Alternate gene names: 146283741

Gene position: 3698472-3699779 (Clockwise)

Preceding gene: 146283740

Following gene: 146283742

Centisome position: 80.98

GC content: 61.31

Gene sequence:

>1308_bases
ATGAAAAAACAGACGGGAATCGCTCTGGCGGTCGCTTTGGTACTGCTGACCGGCGTTGGCGTAAAACAGGGCTTCGTTCT
TGAGGCGCAGGCCAGCGATAACAAGGCTGAGCACGCCGAGGATGGCCACGCGCATGAGGATGGAGAAAGCGGTCACGAGG
AATCTGAGAACGACCATGGGGACGAAGACGGTCATGACGCTGAAGGCGATGGCCACGGCCATGGTGACGAAAGCGGTCAT
GGCGGTGAGGAGGACGAGCACGGCAACGAAACGCATGCCGAAGGTGAGATTGAGCTTTCCGAAGAGCAGATACGTGCCGC
AGGCATTCAGCTAAGCAAGGCCGGACCGGCTGAAATCGGCTCGTCTGTATCTTTGCCGGGCGAGCTGCGTTTCGACGAAG
ACCGTACCGCACATGTCGTGCCCCGTGTGGCCGGCGTTGTCGAATCGGTTTCGGTCAACCTGGGTGACCAAGTGAAGAAG
GGCCAGTTGCTGGCGGTTATCGCCAGCCAGCAGCTGTCCGAACAGCGTAGTGAGCTGGCTGCCGCCGAGCAGCGCCTCCG
ACTGGCTCGCATCTTGTTCGAGCGTGAGCGCACCCTGTGGCAGGAGCGTATCTCTGCAGAACAGGACTATTTGCAGGCCC
AGCAGAGCCTGCGCGTAGCAGAAATCGACTTGCGTAATGCCCAGGAAAAAACCCGGGCGCTGGGCGGCGGAAGTGACGCC
GGTGTGGGTAATCGCTACGAGCTCCGTGCACCTTTCGATGCAGTGGTCGTCGAGAAGCATATTGTGCTGGGCGAACGTGC
AGATGAAACGACCAGCGTCTTCACTCTGACTGATTTGTCGCGGGTTTGGGCCACGTTCAGCGTACCTGCCCGTGATTTGA
TGCGCGTAACCGTCGGCCGAGAAGTCGAAGTTGTTGCCGGCGAGCTAGGCGTGCGAACAATGGGGAAGGTCGCCCATGTG
GGCAGCCTGCTGGGCGAGCAGACGCGTGCCGCGACAGCCCGCGTGACCCTGGCCAACCCCGATGGGGCTTGGCGTCCCGG
TCTTTTCGTGACGGTCCGAGTTAGCGCCGACGGACGTAGTGTTCCGGTCACGGTTCCAGTCGAGGCGGTCCAGACCGTCG
AAAACGCGCCGACGGTTTTCGTTCGCACGCCGCACGGCTTCCAGGCGCACCCGGTTTCGCTGGGCCAGCGCGACGAAAAT
CGCGTGGAAATTCGTGACGGATTGCAGGCCGGCCAACAGATCGCGACCGCTGGCAGCTTCATCCTGAAATCCGAACTCGG
CAAAGGCTCCGCCGAGCACGTTCACTGA

Upstream 100 bases:

>100_bases
TGGTCGACGCCTGGGCGCGTATCGAGCGGCTGTACGGACCTACCACTACCTTCGAATGACCGAAACGCCGCCATTACGTA
TTGGCGGTGGGGGAGCTTGC

Downstream 100 bases:

>100_bases
TCCTCCGGATACCTAACTCATGTTCGAACGTATTCTTCGCTTCGCCATCGAGCAGCGCTGGCTAGTGCTGCTGGCGGTCT
TGGGCATGGCGGGCGTCGGG

Product: CzcB family cobalt/zinc/cadmium efflux transporter membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MKKQTGIALAVALVLLTGVGVKQGFVLEAQASDNKAEHAEDGHAHEDGESGHEESENDHGDEDGHDAEGDGHGHGDESGH
GGEEDEHGNETHAEGEIELSEEQIRAAGIQLSKAGPAEIGSSVSLPGELRFDEDRTAHVVPRVAGVVESVSVNLGDQVKK
GQLLAVIASQQLSEQRSELAAAEQRLRLARILFERERTLWQERISAEQDYLQAQQSLRVAEIDLRNAQEKTRALGGGSDA
GVGNRYELRAPFDAVVVEKHIVLGERADETTSVFTLTDLSRVWATFSVPARDLMRVTVGREVEVVAGELGVRTMGKVAHV
GSLLGEQTRAATARVTLANPDGAWRPGLFVTVRVSADGRSVPVTVPVEAVQTVENAPTVFVRTPHGFQAHPVSLGQRDEN
RVEIRDGLQAGQQIATAGSFILKSELGKGSAEHVH

Sequences:

>Translated_435_residues
MKKQTGIALAVALVLLTGVGVKQGFVLEAQASDNKAEHAEDGHAHEDGESGHEESENDHGDEDGHDAEGDGHGHGDESGH
GGEEDEHGNETHAEGEIELSEEQIRAAGIQLSKAGPAEIGSSVSLPGELRFDEDRTAHVVPRVAGVVESVSVNLGDQVKK
GQLLAVIASQQLSEQRSELAAAEQRLRLARILFERERTLWQERISAEQDYLQAQQSLRVAEIDLRNAQEKTRALGGGSDA
GVGNRYELRAPFDAVVVEKHIVLGERADETTSVFTLTDLSRVWATFSVPARDLMRVTVGREVEVVAGELGVRTMGKVAHV
GSLLGEQTRAATARVTLANPDGAWRPGLFVTVRVSADGRSVPVTVPVEAVQTVENAPTVFVRTPHGFQAHPVSLGQRDEN
RVEIRDGLQAGQQIATAGSFILKSELGKGSAEHVH
>Mature_435_residues
MKKQTGIALAVALVLLTGVGVKQGFVLEAQASDNKAEHAEDGHAHEDGESGHEESENDHGDEDGHDAEGDGHGHGDESGH
GGEEDEHGNETHAEGEIELSEEQIRAAGIQLSKAGPAEIGSSVSLPGELRFDEDRTAHVVPRVAGVVESVSVNLGDQVKK
GQLLAVIASQQLSEQRSELAAAEQRLRLARILFERERTLWQERISAEQDYLQAQQSLRVAEIDLRNAQEKTRALGGGSDA
GVGNRYELRAPFDAVVVEKHIVLGERADETTSVFTLTDLSRVWATFSVPARDLMRVTVGREVEVVAGELGVRTMGKVAHV
GSLLGEQTRAATARVTLANPDGAWRPGLFVTVRVSADGRSVPVTVPVEAVQTVENAPTVFVRTPHGFQAHPVSLGQRDEN
RVEIRDGLQAGQQIATAGSFILKSELGKGSAEHVH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=321, Percent_Identity=26.1682242990654, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46588; Mature: 46588

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQTGIALAVALVLLTGVGVKQGFVLEAQASDNKAEHAEDGHAHEDGESGHEESENDHG
CCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEDGHDAEGDGHGHGDESGHGGEEDEHGNETHAEGEIELSEEQIRAAGIQLSKAGPAEIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHCEEEECCCCHHCC
SSVSLPGELRFDEDRTAHVVPRVAGVVESVSVNLGDQVKKGQLLAVIASQQLSEQRSELA
CCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
AAEQRLRLARILFERERTLWQERISAEQDYLQAQQSLRVAEIDLRNAQEKTRALGGGSDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCCCCC
GVGNRYELRAPFDAVVVEKHIVLGERADETTSVFTLTDLSRVWATFSVPARDLMRVTVGR
CCCCEEEECCCHHHHHHHHHHEECCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHCCC
EVEVVAGELGVRTMGKVAHVGSLLGEQTRAATARVTLANPDGAWRPGLFVTVRVSADGRS
EEEEEECHHCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEECCCCCE
VPVTVPVEAVQTVENAPTVFVRTPHGFQAHPVSLGQRDENRVEIRDGLQAGQQIATAGSF
EEEEECHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILKSELGKGSAEHVH
HHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKQTGIALAVALVLLTGVGVKQGFVLEAQASDNKAEHAEDGHAHEDGESGHEESENDHG
CCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEDGHDAEGDGHGHGDESGHGGEEDEHGNETHAEGEIELSEEQIRAAGIQLSKAGPAEIG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHCEEEECCCCHHCC
SSVSLPGELRFDEDRTAHVVPRVAGVVESVSVNLGDQVKKGQLLAVIASQQLSEQRSELA
CCCCCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
AAEQRLRLARILFERERTLWQERISAEQDYLQAQQSLRVAEIDLRNAQEKTRALGGGSDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHCCCCCCC
GVGNRYELRAPFDAVVVEKHIVLGERADETTSVFTLTDLSRVWATFSVPARDLMRVTVGR
CCCCEEEECCCHHHHHHHHHHEECCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHCCC
EVEVVAGELGVRTMGKVAHVGSLLGEQTRAATARVTLANPDGAWRPGLFVTVRVSADGRS
EEEEEECHHCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCEEEEEEECCCCCE
VPVTVPVEAVQTVENAPTVFVRTPHGFQAHPVSLGQRDENRVEIRDGLQAGQQIATAGSF
EEEEECHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILKSELGKGSAEHVH
HHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]