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The map label for this gene is pcbC [H]

Identifier: 146283409

GI number: 146283409

Start: 3313593

End: 3314567

Strand: Direct

Name: pcbC [H]

Synonym: PST_3080

Alternate gene names: 146283409

Gene position: 3313593-3314567 (Clockwise)

Preceding gene: 146283408

Following gene: 146283410

Centisome position: 72.55

GC content: 64.62

Gene sequence:

>975_bases
ATGAACGCACTGCCCATCATCGATATTTCCCCGCTCTATAACGCCGACGAGGCCGGCCATCTGGCCGTCGCCGAGGCCAT
CGACCGCGCCTGCCGCGAGTGGGGCTTCTTCTATATCAAGGGTCATCCGATCAGCGCCGAGCGCATCGCCACCCTCACCG
ACCATGCCAAGCGTTTCTTTGCCCTGCCCGCCGACGAAAAGCTGAAGATCGATATCACCAAGAGCCGCCATCACCGCGGC
TACGGTGCCGTCGCCACCGAGCAGCTGGACCCGAGCCAGCCGTGCGACCTCAAGGAAACCTTCGACATGGGTTTCCATAT
GCCTGCCGATCATCCGGAGGTACTGGCCGGCAAACCGCTGCGCGGGCCCAACCGTCATCCGCTGCAGATCGAAGGCTGGA
CCGAGCTGATGGAAGGGCACTACCGCGACATGCAGGACCTTGCCTGCACGCTTCTGCGTGCCATCGCACTCGCCCTTGGC
ATCGAGCGGGACTTCTTCGACAAGCGCTTCGTCGAGCCCATCAGCGTGTTTCGCATGATCCACTACCCGCCCCGGCAGAC
CGCCACCAGCGCCGATCAGCAAGGCGCCGGCGCGCACACCGATTACGGCTGCGTCACCCTGCTCTATCAGGACCAGGCCG
GCGGCCTGCAGGTGCAGAACGTCAAGGGCGAGTGGATCGACGCACCGCCCATCGAGGGCACCTACGTGGTCAACATCGGC
GACATGATGGCGCGCTGGAGCAACGACCGTTACAAGTCGACGCCCCATCGCGTGATCAGCCCGCTGGGCGTGGACCGCTA
CTCCATGCCGTTCTTCGCCGAGCCGCATCCGGACACCGAGATCGCCTGCCTGCCCGGTTGCTACGACGAAACCAACCCGC
CGAAATACCCGAGCACCACCTGCAGCCGGTACATGCTCTCGCGCTTCGCCGAGACCTACGCCTACCGACGGCAGGGCGAG
GCCGAACCCGTCTGA

Upstream 100 bases:

>100_bases
TCGCGTGCCGTCCCGCCTCCGGGCGAACCGCACGCAGGGGGCATTGCCCTCGAAGGCCGCCGGTACGAGAAGACCGGCGG
CACCGTACCCGGAGTCAGCC

Downstream 100 bases:

>100_bases
ACGGGCTTTAATTGCAGTATGCAAACAGGGGCGAGCGCATCGATATGCCTCGCCCGATCTGCGCGCGTCTGCCGCATTGA
CTTTTGAGTCAGGAATTAGT

Product: 2OG-Fe(II) oxygenase family oxidoreductase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MNALPIIDISPLYNADEAGHLAVAEAIDRACREWGFFYIKGHPISAERIATLTDHAKRFFALPADEKLKIDITKSRHHRG
YGAVATEQLDPSQPCDLKETFDMGFHMPADHPEVLAGKPLRGPNRHPLQIEGWTELMEGHYRDMQDLACTLLRAIALALG
IERDFFDKRFVEPISVFRMIHYPPRQTATSADQQGAGAHTDYGCVTLLYQDQAGGLQVQNVKGEWIDAPPIEGTYVVNIG
DMMARWSNDRYKSTPHRVISPLGVDRYSMPFFAEPHPDTEIACLPGCYDETNPPKYPSTTCSRYMLSRFAETYAYRRQGE
AEPV

Sequences:

>Translated_324_residues
MNALPIIDISPLYNADEAGHLAVAEAIDRACREWGFFYIKGHPISAERIATLTDHAKRFFALPADEKLKIDITKSRHHRG
YGAVATEQLDPSQPCDLKETFDMGFHMPADHPEVLAGKPLRGPNRHPLQIEGWTELMEGHYRDMQDLACTLLRAIALALG
IERDFFDKRFVEPISVFRMIHYPPRQTATSADQQGAGAHTDYGCVTLLYQDQAGGLQVQNVKGEWIDAPPIEGTYVVNIG
DMMARWSNDRYKSTPHRVISPLGVDRYSMPFFAEPHPDTEIACLPGCYDETNPPKYPSTTCSRYMLSRFAETYAYRRQGE
AEPV
>Mature_324_residues
MNALPIIDISPLYNADEAGHLAVAEAIDRACREWGFFYIKGHPISAERIATLTDHAKRFFALPADEKLKIDITKSRHHRG
YGAVATEQLDPSQPCDLKETFDMGFHMPADHPEVLAGKPLRGPNRHPLQIEGWTELMEGHYRDMQDLACTLLRAIALALG
IERDFFDKRFVEPISVFRMIHYPPRQTATSADQQGAGAHTDYGCVTLLYQDQAGGLQVQNVKGEWIDAPPIEGTYVVNIG
DMMARWSNDRYKSTPHRVISPLGVDRYSMPFFAEPHPDTEIACLPGCYDETNPPKYPSTTCSRYMLSRFAETYAYRRQGE
AEPV

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI28572124, Length=341, Percent_Identity=26.9794721407625, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI85816264, Length=303, Percent_Identity=28.3828382838284, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 36530; Mature: 36530

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPIIDISPLYNADEAGHLAVAEAIDRACREWGFFYIKGHPISAERIATLTDHAKRFF
CCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHEE
ALPADEKLKIDITKSRHHRGYGAVATEQLDPSQPCDLKETFDMGFHMPADHPEVLAGKPL
ECCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHCCCCCCCCCCCHHHCCCCC
RGPNRHPLQIEGWTELMEGHYRDMQDLACTLLRAIALALGIERDFFDKRFVEPISVFRMI
CCCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HYPPRQTATSADQQGAGAHTDYGCVTLLYQDQAGGLQVQNVKGEWIDAPPIEGTYVVNIG
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEHH
DMMARWSNDRYKSTPHRVISPLGVDRYSMPFFAEPHPDTEIACLPGCYDETNPPKYPSTT
HHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHH
CSRYMLSRFAETYAYRRQGEAEPV
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNALPIIDISPLYNADEAGHLAVAEAIDRACREWGFFYIKGHPISAERIATLTDHAKRFF
CCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHEE
ALPADEKLKIDITKSRHHRGYGAVATEQLDPSQPCDLKETFDMGFHMPADHPEVLAGKPL
ECCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHCCCCCCCCCCCHHHCCCCC
RGPNRHPLQIEGWTELMEGHYRDMQDLACTLLRAIALALGIERDFFDKRFVEPISVFRMI
CCCCCCCEEECCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
HYPPRQTATSADQQGAGAHTDYGCVTLLYQDQAGGLQVQNVKGEWIDAPPIEGTYVVNIG
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEEHH
DMMARWSNDRYKSTPHRVISPLGVDRYSMPFFAEPHPDTEIACLPGCYDETNPPKYPSTT
HHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHH
CSRYMLSRFAETYAYRRQGEAEPV
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3130293 [H]