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The map label for this gene is xseA

Identifier: 146283340

GI number: 146283340

Start: 3240737

End: 3242113

Strand: Direct

Name: xseA

Synonym: PST_3010

Alternate gene names: 146283340

Gene position: 3240737-3242113 (Clockwise)

Preceding gene: 146283334

Following gene: 146283341

Centisome position: 70.95

GC content: 69.21

Gene sequence:

>1377_bases
ATGCTCAAAGATCCCTTCCAGCGCCTCAATCTCGATCGCGAAGTGCTGACCGTCAGTCAGCTCAACGGTCGCGCCCGCCT
GTTGCTCGAGGACGTGTTCGCCCAGGTCTGGGTCGAAGGCGAGATTTCCAACCTCGCCCGCCCCGCCTCCGGCCACGTCT
ATTTCACCCTCAAGGACAGGAACGCCCAGGTGCGTTGCGCCCTTTTCCGCCAGAATGCCGCGCGGGTACGTCAGGCACTG
CGCGACGGCCTGGCGGTGCGGGTGCGTGGCAAGGTCTCGCTGTTCGAAGGCCGTGGCGACTATCAGCTGATCCTCGACAT
GCTGGAGCCGGCCGGCGACGGCGCACTGCGCCTGGCCTTCGAAGCGCTGAAGGAAAAGCTCGCCGCCGAAGGCCTGTTCT
CCGCCGAGCGCAAGGCCGCCCTGCCCGCTCATCCGCGGCGCATCGGCATCGTCAGCTCACCGACCGGCGCAGTGATCCGC
GACATCATCTCGGTGTTTCGCCGCCGCGCACCGCAGGTGGAGCTGACGCTGATCCCCACCGCCGTACAGGGCCGCGAAGC
CACTGGGCAGATCGTCCGTGCGCTGCAGCTGGCGGACGCCCAGGGCTTCGACGCCCTGATCCTCGCCCGCGGCGGCGGCT
CGCTGGAAGATCTCTGGTGCTTCAACGAGGAAGCCGTGGCGCGTGCGGTGGATGCCTGCGTCACGCCGATCGTCTGCGCG
GTTGGCCATGAGACCGATGTGTCCATCGCCGACTTCGTCGCCGATGTGCGCGCCCCGACGCCGTCCGCGGCGGCAGAGCT
GCTGGCGCCTAGCAGTGCCGATCTGCAGCAGCGGCTGAACGGCCTGCAGCAACGGCTGGTACTGCGCATGCGTGATCGCC
TGCACCGCGACGCCATGCGCCTGGACGGCCTGACCCGCCGCCTGCGCCATCCCGGCGAGCGTCTGCAGCAGCAGGCCCAG
CGTATCGATGACCTGGAGCAGCGCCTGCTGCGGGCCCTGGACCGCCGCCTGTGCAGTGGCCAGGAGCGCCTGGCCCGACT
GGAAACACGCCTGGCCGCGCAGCATCCGGGGCGCACGCTGAATCTGCTGCGCCAGCGCCTCGACCATCTGTCCTCGCGCC
TGCCGCGGGCGATGCAGGCCAATATTAAAGGCCGCCGCCAGCAGCTGCAGGGCCTGGCCCAGACGCTCAACGTGGTCAGC
CCGCTGGCCACGCTCAGCCGCGGCTACAGCATCCTGCTCGACGACCGCGGCCAGGCGATCCGCAGCGCCAGTCAGACGCA
ACCCGGCCAGCGCCTCAAGGCCAGGCTCGGCGACGGCGAGCTCGACGTACGCGTGGAGGACAATCACCTGCAACCGGTCA
CCCTGCCGCTGCTCTAA

Upstream 100 bases:

>100_bases
CGCGCAGCTTAGCGCCGCCCGTAGGCTGGTCAAGGCCCGCTGGACGGACGCCAAGCAGATTCGGTTTCCGCTTGGCCGCG
CGCGGCTTATCATCGCCGCC

Downstream 100 bases:

>100_bases
GCAAGCCGAGCCGGCAATCTCCTGACATTCTTGGCCCTTTCTCTTGCCGGAGGTTTACGCGAGGATGGGCCGTTTCCTGC
AACGGACCCATCCATGTCTC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLKDPFQRLNLDREVLTVSQLNGRARLLLEDVFAQVWVEGEISNLARPASGHVYFTLKDRNAQVRCALFRQNAARVRQAL
RDGLAVRVRGKVSLFEGRGDYQLILDMLEPAGDGALRLAFEALKEKLAAEGLFSAERKAALPAHPRRIGIVSSPTGAVIR
DIISVFRRRAPQVELTLIPTAVQGREATGQIVRALQLADAQGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVCA
VGHETDVSIADFVADVRAPTPSAAAELLAPSSADLQQRLNGLQQRLVLRMRDRLHRDAMRLDGLTRRLRHPGERLQQQAQ
RIDDLEQRLLRALDRRLCSGQERLARLETRLAAQHPGRTLNLLRQRLDHLSSRLPRAMQANIKGRRQQLQGLAQTLNVVS
PLATLSRGYSILLDDRGQAIRSASQTQPGQRLKARLGDGELDVRVEDNHLQPVTLPLL

Sequences:

>Translated_458_residues
MLKDPFQRLNLDREVLTVSQLNGRARLLLEDVFAQVWVEGEISNLARPASGHVYFTLKDRNAQVRCALFRQNAARVRQAL
RDGLAVRVRGKVSLFEGRGDYQLILDMLEPAGDGALRLAFEALKEKLAAEGLFSAERKAALPAHPRRIGIVSSPTGAVIR
DIISVFRRRAPQVELTLIPTAVQGREATGQIVRALQLADAQGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVCA
VGHETDVSIADFVADVRAPTPSAAAELLAPSSADLQQRLNGLQQRLVLRMRDRLHRDAMRLDGLTRRLRHPGERLQQQAQ
RIDDLEQRLLRALDRRLCSGQERLARLETRLAAQHPGRTLNLLRQRLDHLSSRLPRAMQANIKGRRQQLQGLAQTLNVVS
PLATLSRGYSILLDDRGQAIRSASQTQPGQRLKARLGDGELDVRVEDNHLQPVTLPLL
>Mature_458_residues
MLKDPFQRLNLDREVLTVSQLNGRARLLLEDVFAQVWVEGEISNLARPASGHVYFTLKDRNAQVRCALFRQNAARVRQAL
RDGLAVRVRGKVSLFEGRGDYQLILDMLEPAGDGALRLAFEALKEKLAAEGLFSAERKAALPAHPRRIGIVSSPTGAVIR
DIISVFRRRAPQVELTLIPTAVQGREATGQIVRALQLADAQGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVCA
VGHETDVSIADFVADVRAPTPSAAAELLAPSSADLQQRLNGLQQRLVLRMRDRLHRDAMRLDGLTRRLRHPGERLQQQAQ
RIDDLEQRLLRALDRRLCSGQERLARLETRLAAQHPGRTLNLLRQRLDHLSSRLPRAMQANIKGRRQQLQGLAQTLNVVS
PLATLSRGYSILLDDRGQAIRSASQTQPGQRLKARLGDGELDVRVEDNHLQPVTLPLL

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=442, Percent_Identity=44.1176470588235, Blast_Score=357, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_PSEU5 (A4VNV0)

Other databases:

- EMBL:   CP000304
- RefSeq:   YP_001173493.1
- STRING:   A4VNV0
- GeneID:   5095972
- GenomeReviews:   CP000304_GR
- KEGG:   psa:PST_3010
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   SSQIRCA
- PhylomeDB:   A4VNV0
- ProtClustDB:   PRK00286
- BioCyc:   PSTU379731:PST_3010-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 50815; Mature: 50815

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKDPFQRLNLDREVLTVSQLNGRARLLLEDVFAQVWVEGEISNLARPASGHVYFTLKDR
CCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEECC
NAQVRCALFRQNAARVRQALRDGLAVRVRGKVSLFEGRGDYQLILDMLEPAGDGALRLAF
CCEEEHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHCCCCCCHHHHHH
EALKEKLAAEGLFSAERKAALPAHPRRIGIVSSPTGAVIRDIISVFRRRAPQVELTLIPT
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECC
AVQGREATGQIVRALQLADAQGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVCA
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
VGHETDVSIADFVADVRAPTPSAAAELLAPSSADLQQRLNGLQQRLVLRMRDRLHRDAMR
CCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDGLTRRLRHPGERLQQQAQRIDDLEQRLLRALDRRLCSGQERLARLETRLAAQHPGRTL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHH
NLLRQRLDHLSSRLPRAMQANIKGRRQQLQGLAQTLNVVSPLATLSRGYSILLDDRGQAI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHH
RSASQTQPGQRLKARLGDGELDVRVEDNHLQPVTLPLL
HHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCEECCCC
>Mature Secondary Structure
MLKDPFQRLNLDREVLTVSQLNGRARLLLEDVFAQVWVEGEISNLARPASGHVYFTLKDR
CCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEEEECC
NAQVRCALFRQNAARVRQALRDGLAVRVRGKVSLFEGRGDYQLILDMLEPAGDGALRLAF
CCEEEHHHHHHHHHHHHHHHHCCCEEEEECCEEEEECCCCHHHHHHHHCCCCCCHHHHHH
EALKEKLAAEGLFSAERKAALPAHPRRIGIVSSPTGAVIRDIISVFRRRAPQVELTLIPT
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEECC
AVQGREATGQIVRALQLADAQGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVCA
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHCCCHHHHHHHHHHHHHHHHHH
VGHETDVSIADFVADVRAPTPSAAAELLAPSSADLQQRLNGLQQRLVLRMRDRLHRDAMR
CCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDGLTRRLRHPGERLQQQAQRIDDLEQRLLRALDRRLCSGQERLARLETRLAAQHPGRTL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHH
NLLRQRLDHLSSRLPRAMQANIKGRRQQLQGLAQTLNVVSPLATLSRGYSILLDDRGQAI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHH
RSASQTQPGQRLKARLGDGELDVRVEDNHLQPVTLPLL
HHHHCCCCHHHHHHHCCCCEEEEEEECCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA