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The map label for this gene is guaA [H]

Identifier: 146283037

GI number: 146283037

Start: 2922471

End: 2923040

Strand: Direct

Name: guaA [H]

Synonym: PST_2698

Alternate gene names: 146283037

Gene position: 2922471-2923040 (Clockwise)

Preceding gene: 146283036

Following gene: 146283038

Centisome position: 63.99

GC content: 63.86

Gene sequence:

>570_bases
ATGCCGAACCCGATCGAATTCGAAACCGAACGCCTGTTCATGCGGCAATGGCGCCCGAGCGACCGGGCGCCCTTTGCCGA
ACTGAACGCAGACCCGCGGGTCATGGACTATTTCCCTGCTCCGCTCGAGCGCGACGAGAGCGATGCGCTGGCCGATCGCT
GCCAGGCGCTGATCGAGCAGCGAGGATGGGGTTTCTGGGCCGTGGAGCTGAAGGCATCCGCCGAGTTCATCGGCTTTCTC
GGCCTGCATGTACCAATCGCCGAGCTGCCCTTTTCGCCCTGCGTGGAGATCGGCTGGCGCCTGGCCTTCCAGCACTGGCA
CAGAGGTTTGGCAACGGAGGCAGCGCGCGGTGCGCTCGAGGTGGGCTTCGACAGGCTGGATTTGGCGGAAATCGTCTCTT
TCACCACGCTCGGCAATCAGCGTTCGCGCGCGGTCATGCAACGAATCGGCATGCGCGAGGCGAGCCGCTTCGAGCATCCG
AGCATACCCATCGGTCATCCACTTCGCGCACACTGCCTGTACCGTCTTTCGCAGGTGGACTATCGGGCGCAGCGGATTGC
AGGCGACTGA

Upstream 100 bases:

>100_bases
AGCTATTCAGGTGATTCCGGTTAGCCGCGGCCAAGTCGCCGCCCTTGCTGCAAAAGGAGCGGCGAGCAACAGCCTCCTCC
TTTGATCCGAGAACACTGCA

Downstream 100 bases:

>100_bases
GCCCCGTCCGAACACGCTCCCACCTACAACCTGGTCCTGGTCATGCCCGCCCTGTTGCTCTCGCTGTTACTGCTCGCTGC
TCCCGGCTTCGCCCATGCGG

Product: acetyltransferase

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MPNPIEFETERLFMRQWRPSDRAPFAELNADPRVMDYFPAPLERDESDALADRCQALIEQRGWGFWAVELKASAEFIGFL
GLHVPIAELPFSPCVEIGWRLAFQHWHRGLATEAARGALEVGFDRLDLAEIVSFTTLGNQRSRAVMQRIGMREASRFEHP
SIPIGHPLRAHCLYRLSQVDYRAQRIAGD

Sequences:

>Translated_189_residues
MPNPIEFETERLFMRQWRPSDRAPFAELNADPRVMDYFPAPLERDESDALADRCQALIEQRGWGFWAVELKASAEFIGFL
GLHVPIAELPFSPCVEIGWRLAFQHWHRGLATEAARGALEVGFDRLDLAEIVSFTTLGNQRSRAVMQRIGMREASRFEHP
SIPIGHPLRAHCLYRLSQVDYRAQRIAGD
>Mature_188_residues
PNPIEFETERLFMRQWRPSDRAPFAELNADPRVMDYFPAPLERDESDALADRCQALIEQRGWGFWAVELKASAEFIGFLG
LHVPIAELPFSPCVEIGWRLAFQHWHRGLATEAARGALEVGFDRLDLAEIVSFTTLGNQRSRAVMQRIGMREASRFEHPS
IPIGHPLRAHCLYRLSQVDYRAQRIAGD

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG1670

COG function: function code J; Acetyltransferases, including N-acetylases of ribosomal proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 21646; Mature: 21515

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNPIEFETERLFMRQWRPSDRAPFAELNADPRVMDYFPAPLERDESDALADRCQALIEQ
CCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
RGWGFWAVELKASAEFIGFLGLHVPIAELPFSPCVEIGWRLAFQHWHRGLATEAARGALE
CCCCEEEEEEECCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFDRLDLAEIVSFTTLGNQRSRAVMQRIGMREASRFEHPSIPIGHPLRAHCLYRLSQVD
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
YRAQRIAGD
HHHHHHCCC
>Mature Secondary Structure 
PNPIEFETERLFMRQWRPSDRAPFAELNADPRVMDYFPAPLERDESDALADRCQALIEQ
CCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHH
RGWGFWAVELKASAEFIGFLGLHVPIAELPFSPCVEIGWRLAFQHWHRGLATEAARGALE
CCCCEEEEEEECCHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGFDRLDLAEIVSFTTLGNQRSRAVMQRIGMREASRFEHPSIPIGHPLRAHCLYRLSQVD
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
YRAQRIAGD
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]