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The map label for this gene is lcr1 [H]

Identifier: 146283038

GI number: 146283038

Start: 2923083

End: 2923865

Strand: Direct

Name: lcr1 [H]

Synonym: PST_2699

Alternate gene names: 146283038

Gene position: 2923083-2923865 (Clockwise)

Preceding gene: 146283037

Following gene: 146283039

Centisome position: 64.0

GC content: 65.77

Gene sequence:

>783_bases
ATGCCCGCCCTGTTGCTCTCGCTGTTACTGCTCGCTGCTCCCGGCTTCGCCCATGCGGAGGACGGGGCAATTTCCCGTCT
GTTCGAACGCGCGGGGGTCGAGGGGACACTGGTCATCGAGTCCGTCGCCACGGGCCAGCGCTTCGTCCACAACGATGAAC
GCGCCGGCACGGCTTTTCCCGCAGCGTCCACGTTCAAGGTGCTGAACACTCTGATCGCACTGGAGGAAGGCGCCATCGCC
GGGGCGGACGAGATCATCCCCTGGGACGGCACCCGTTACGAGATAGAGGACTGGAACCGCGACCAGACCTTGAAGAGCGC
ATTCAGGGTCAGCTGCGTCTGGTGCTACCAGAGGCTGGCCCGGCGGGTGGGCGCGGCGGCCTATCTGCGCCACATCCGCC
AGGCGCATTACGGGCAGCTGCACGAACCTGTCAATGTCACCGAGTTCTGGCTCGATGGCTCGCTGCGCGTCAGCGCCGAA
CAACAGGTGGGTCTGCTGCGCCAGGTGGTCGCACGCAGCCTGCCGTACCGGGCGAAGAGCTACGACACCCTCAGGACCAT
CATGCGCGTCGACAGCACGCCGGCTTATAGCCTGTATGCCAAGACCGGTTGGGCGGCTCGCGACAATCCTGGCATCGGCT
GGTACATCGGCTATGTTGAAGCCGGCGCCGACACCTGGCTGTTCGCGCTGAATCTGGACACCCGCGATGCGACCGATCTG
CCCCTGCGCCAGCGGATCGCGCTGGATGCGCTGCGGGCGAAGGGCATACTCCCGGCCCAGTGA

Upstream 100 bases:

>100_bases
CTGCCTGTACCGTCTTTCGCAGGTGGACTATCGGGCGCAGCGGATTGCAGGCGACTGAGCCCCGTCCGAACACGCTCCCA
CCTACAACCTGGTCCTGGTC

Downstream 100 bases:

>100_bases
TTCTTCCAATGGTCCGCGGCAGCAACCCGGCGACGCCGCGTTCCACACCACACCAAACGGAGCCACCATGCGCAGCGACG
AGATCAAAGCGGTATTCGAT

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MPALLLSLLLLAAPGFAHAEDGAISRLFERAGVEGTLVIESVATGQRFVHNDERAGTAFPAASTFKVLNTLIALEEGAIA
GADEIIPWDGTRYEIEDWNRDQTLKSAFRVSCVWCYQRLARRVGAAAYLRHIRQAHYGQLHEPVNVTEFWLDGSLRVSAE
QQVGLLRQVVARSLPYRAKSYDTLRTIMRVDSTPAYSLYAKTGWAARDNPGIGWYIGYVEAGADTWLFALNLDTRDATDL
PLRQRIALDALRAKGILPAQ

Sequences:

>Translated_260_residues
MPALLLSLLLLAAPGFAHAEDGAISRLFERAGVEGTLVIESVATGQRFVHNDERAGTAFPAASTFKVLNTLIALEEGAIA
GADEIIPWDGTRYEIEDWNRDQTLKSAFRVSCVWCYQRLARRVGAAAYLRHIRQAHYGQLHEPVNVTEFWLDGSLRVSAE
QQVGLLRQVVARSLPYRAKSYDTLRTIMRVDSTPAYSLYAKTGWAARDNPGIGWYIGYVEAGADTWLFALNLDTRDATDL
PLRQRIALDALRAKGILPAQ
>Mature_259_residues
PALLLSLLLLAAPGFAHAEDGAISRLFERAGVEGTLVIESVATGQRFVHNDERAGTAFPAASTFKVLNTLIALEEGAIAG
ADEIIPWDGTRYEIEDWNRDQTLKSAFRVSCVWCYQRLARRVGAAAYLRHIRQAHYGQLHEPVNVTEFWLDGSLRVSAEQ
QVGLLRQVVARSLPYRAKSYDTLRTIMRVDSTPAYSLYAKTGWAARDNPGIGWYIGYVEAGADTWLFALNLDTRDATDLP
LRQRIALDALRAKGILPAQ

Specific function: This oxacillinase hydrolyzes methicillin [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 28830; Mature: 28699

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALLLSLLLLAAPGFAHAEDGAISRLFERAGVEGTLVIESVATGQRFVHNDERAGTAFP
CHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEEHHCCHHHHCCCCCCCCCCC
AASTFKVLNTLIALEEGAIAGADEIIPWDGTRYEIEDWNRDQTLKSAFRVSCVWCYQRLA
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RRVGAAAYLRHIRQAHYGQLHEPVNVTEFWLDGSLRVSAEQQVGLLRQVVARSLPYRAKS
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHCCCCCCH
YDTLRTIMRVDSTPAYSLYAKTGWAARDNPGIGWYIGYVEAGADTWLFALNLDTRDATDL
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCC
PLRQRIALDALRAKGILPAQ
CHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PALLLSLLLLAAPGFAHAEDGAISRLFERAGVEGTLVIESVATGQRFVHNDERAGTAFP
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEEHHCCHHHHCCCCCCCCCCC
AASTFKVLNTLIALEEGAIAGADEIIPWDGTRYEIEDWNRDQTLKSAFRVSCVWCYQRLA
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RRVGAAAYLRHIRQAHYGQLHEPVNVTEFWLDGSLRVSAEQQVGLLRQVVARSLPYRAKS
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEECCHHHHHHHHHHHHHHCCCCCCH
YDTLRTIMRVDSTPAYSLYAKTGWAARDNPGIGWYIGYVEAGADTWLFALNLDTRDATDL
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCCC
PLRQRIALDALRAKGILPAQ
CHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1495394 [H]