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The map label for this gene is lig [H]

Identifier: 146283000

GI number: 146283000

Start: 2882435

End: 2883451

Strand: Direct

Name: lig [H]

Synonym: PST_2661

Alternate gene names: 146283000

Gene position: 2882435-2883451 (Clockwise)

Preceding gene: 146282999

Following gene: 146283001

Centisome position: 63.11

GC content: 66.27

Gene sequence:

>1017_bases
ATGGATCTTGTCGTTGCCCGCCCCGAAGGGCTGTATTGCCCGCCCGGTGATTTCTATATCGACCCCTGGCGGCCGGTCGA
TCGCGCCGTCATAACCCACGCCCATGGCGACCACGCACGCTGGGGGATGGGCCATTACCTGGCTTCCAGCGACAGCGAAG
GCATCCTGCGTTCGCGCATCGCCGCGGATATGCCGCTGCAGACACTGGCCTATGGCGAATCCATCGAGCATCACGGCGTA
AAGCTCAGCTTTCATCCCGCTGGTCATGTACTCGGCTCGGCCCAGGTGCGCCTGGAATACAAGGGCGAAGTCTGGGTCGC
TTCGGGCGACTACAAGGTCGAGCCGGACGGCACCTGCGCGCCGTTCGAGCCGGTGCGCTGCCATACCTTCATCACCGAAT
CGACCTTCGGCCTGCCGATCTACAAGTGGCCGGCGCAAACCGAGGTCTTCCGCGAGATCAACGATTGGTGGCGCGCCAAC
GCCGCGGCCGGGCGCGCCAGCGTGCTGTTCTGCTATGCCTTCGGCAAGGCGCAGCGCATCCTGCACGGCCTGGATGAAAG
CATCGGCACCATCGTCGTGCATGGCGCGGTAGAGCCGCTGAACAAGGTCTATCGCGAGGGCGGCATCCACCTGCCGCCGA
CGGTGTATGCCGGTGACCTGAAGAAGGGTGATCCGCGCCTGAAGCAGGCCATCATCCTCGCCCCGCCCTCGGCTGGCGGC
AGCACATGGATGCGCCGCTTCGGTGACTATGCCGACGCCTTCGCCAGCGGCTGGATGATGCTGCGCGGCACCCGCCGTCG
CCGCGGCGTCGACCGCGGCTTCGTGCTTTCCGACCACGCCGACTGGCCAGGCCTGCTCTGGGCCATCGAGCAGACCGGCG
CCGAACGGGTAATGGTCACCCACGGCTCCGTTGCGGTGCTGGTGCGCTACCTGCGCGAAATGCGCGGCCTTGATGCCCAG
GCCTTCGCCACCGAATACGGCGAAGAGGACGATGCCGCGACGGAGGGCACCGCATGA

Upstream 100 bases:

>100_bases
CGACCGGTAGGGTGGGCTTCGGCCCACCTCGCGCTGATCGGGCGAACTCGCAGCGCTGCGCCATGCTCCAAACCTACAAG
CCCGCAAAGCGCCTGTACTC

Downstream 100 bases:

>100_bases
TCGAAGGCCACGCCGCTTTCCCGTGGCGCGGCGACCGCCGAAGCGGAGGCGCCGCATGAAAGCCTTCGCCACGCTCTACA
GTCGCCTGGACGCCACCACG

Product: mRNA 3'-end processing factor

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MDLVVARPEGLYCPPGDFYIDPWRPVDRAVITHAHGDHARWGMGHYLASSDSEGILRSRIAADMPLQTLAYGESIEHHGV
KLSFHPAGHVLGSAQVRLEYKGEVWVASGDYKVEPDGTCAPFEPVRCHTFITESTFGLPIYKWPAQTEVFREINDWWRAN
AAAGRASVLFCYAFGKAQRILHGLDESIGTIVVHGAVEPLNKVYREGGIHLPPTVYAGDLKKGDPRLKQAIILAPPSAGG
STWMRRFGDYADAFASGWMMLRGTRRRRGVDRGFVLSDHADWPGLLWAIEQTGAERVMVTHGSVAVLVRYLREMRGLDAQ
AFATEYGEEDDAATEGTA

Sequences:

>Translated_338_residues
MDLVVARPEGLYCPPGDFYIDPWRPVDRAVITHAHGDHARWGMGHYLASSDSEGILRSRIAADMPLQTLAYGESIEHHGV
KLSFHPAGHVLGSAQVRLEYKGEVWVASGDYKVEPDGTCAPFEPVRCHTFITESTFGLPIYKWPAQTEVFREINDWWRAN
AAAGRASVLFCYAFGKAQRILHGLDESIGTIVVHGAVEPLNKVYREGGIHLPPTVYAGDLKKGDPRLKQAIILAPPSAGG
STWMRRFGDYADAFASGWMMLRGTRRRRGVDRGFVLSDHADWPGLLWAIEQTGAERVMVTHGSVAVLVRYLREMRGLDAQ
AFATEYGEEDDAATEGTA
>Mature_338_residues
MDLVVARPEGLYCPPGDFYIDPWRPVDRAVITHAHGDHARWGMGHYLASSDSEGILRSRIAADMPLQTLAYGESIEHHGV
KLSFHPAGHVLGSAQVRLEYKGEVWVASGDYKVEPDGTCAPFEPVRCHTFITESTFGLPIYKWPAQTEVFREINDWWRAN
AAAGRASVLFCYAFGKAQRILHGLDESIGTIVVHGAVEPLNKVYREGGIHLPPTVYAGDLKKGDPRLKQAIILAPPSAGG
STWMRRFGDYADAFASGWMMLRGTRRRRGVDRGFVLSDHADWPGLLWAIEQTGAERVMVTHGSVAVLVRYLREMRGLDAQ
AFATEYGEEDDAATEGTA

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 37348; Mature: 37348

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLVVARPEGLYCPPGDFYIDPWRPVDRAVITHAHGDHARWGMGHYLASSDSEGILRSRI
CCEEEECCCCCCCCCCCEEECCCCCCCHHEEECCCCCCCCCCCCCEECCCCCCHHHHHHH
AADMPLQTLAYGESIEHHGVKLSFHPAGHVLGSAQVRLEYKGEVWVASGDYKVEPDGTCA
HHCCCHHHHHHCCCHHHCCEEEEECCCCCEECCEEEEEEECCEEEEECCCEEECCCCCCC
PFEPVRCHTFITESTFGLPIYKWPAQTEVFREINDWWRANAAAGRASVLFCYAFGKAQRI
CCCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHH
LHGLDESIGTIVVHGAVEPLNKVYREGGIHLPPTVYAGDLKKGDPRLKQAIILAPPSAGG
HHHHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHEEEEEECCCCCH
STWMRRFGDYADAFASGWMMLRGTRRRRGVDRGFVLSDHADWPGLLWAIEQTGAERVMVT
HHHHHHHHHHHHHHHHCEEEEECCHHHCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEE
HGSVAVLVRYLREMRGLDAQAFATEYGEEDDAATEGTA
CCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDLVVARPEGLYCPPGDFYIDPWRPVDRAVITHAHGDHARWGMGHYLASSDSEGILRSRI
CCEEEECCCCCCCCCCCEEECCCCCCCHHEEECCCCCCCCCCCCCEECCCCCCHHHHHHH
AADMPLQTLAYGESIEHHGVKLSFHPAGHVLGSAQVRLEYKGEVWVASGDYKVEPDGTCA
HHCCCHHHHHHCCCHHHCCEEEEECCCCCEECCEEEEEEECCEEEEECCCEEECCCCCCC
PFEPVRCHTFITESTFGLPIYKWPAQTEVFREINDWWRANAAAGRASVLFCYAFGKAQRI
CCCCCEEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHH
LHGLDESIGTIVVHGAVEPLNKVYREGGIHLPPTVYAGDLKKGDPRLKQAIILAPPSAGG
HHHHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHEEEEEECCCCCH
STWMRRFGDYADAFASGWMMLRGTRRRRGVDRGFVLSDHADWPGLLWAIEQTGAERVMVT
HHHHHHHHHHHHHHHHCEEEEECCHHHCCCCCCEEEECCCCCCCEEEEEECCCCCEEEEE
HGSVAVLVRYLREMRGLDAQAFATEYGEEDDAATEGTA
CCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA