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The map label for this gene is sdcS [H]

Identifier: 146282852

GI number: 146282852

Start: 2742375

End: 2743823

Strand: Direct

Name: sdcS [H]

Synonym: PST_2511

Alternate gene names: 146282852

Gene position: 2742375-2743823 (Clockwise)

Preceding gene: 146282851

Following gene: 146282856

Centisome position: 60.04

GC content: 65.29

Gene sequence:

>1449_bases
ATGGCGGAATCATCTCAAAGCCGGGGCGCCGTACTGGCCGCGTGGATCGGCCTGATCCTGGGCCCACTGCTGTTGCTGGC
CTGCATCCTGACCGACCCACCCGGCGGCCTTTCGGAAAAGGCCTGGCTGACCGTGGGCCTGGCCGCGCTGATGGCGGTCT
GGTGGTCGACCGAGGCGATACCGATCCCGGCGACCTCGCTGTTGCCGATTCTGCTGATACCCCTGCTCGACATCGATACC
CTGGCCAAGGCCACCGCGCCCTATGCCAACCCGACCATCTTTCTCTTCCTCGGCGGTTTTCTGCTCGGCCTGGCGATGCA
GCGCTGGAACCTGCACAAACGCATCGCCCTGGCGACGCTGCTGGCGGTGGGTAACCAGCCGAGCCGGCAGATCGCCGGCT
TCATGATCGCCACGGCGTTCATCAGCATGTGGGTGAGCAATACGGCGACCAGCATCATGATGCTGCCCATCGGCCTGTCG
GTCATCGGCCTGCTGATCGCCGGCAGCGAGGAAAAGGAAGGCGCGCGGTTCGCCGTGGCGCTGCTGCTGGGCATCGCCTA
TTCGGCCAGCGTCGGCGGCATCGCTACGCTCATCGGCACCCCGCCCAATGCCCTGCTGGCGGCGTTCATGCGGGAGAACT
ACGACGTCCAGATCGGCTTCGGCCAGTGGATGCTGCTGGGCCTGCCGCTGAGCATCGGCATGCTGGTCTTCATCTGGTGG
TCGCTCACCCGCGGCGGTTTTCGCCTGGCGGGGGGCGACAGCCGTGGTCTGCTCGAAAAGGAAATGGCCGCACTCGGGCC
GATGTCGCGTGCCGAAAAAATGGTCGCCGTGGTGTTCGTGCTGGCAGCGGCGGCCTGGATCTTCCAGCCACTGCTGGCCG
ACTATATCGATGGCGTGAACGACACCAGCATTGCCATGGCGGCAGCGATCGCACTGTTCCTGATTCCAGTTGACCTGCAC
AAACGGGTGTTTCTGATGGATTGGGAGCAGGCCAACAAGGCGCCGTGGGGCGTGCTGCTGCTGTTCGGCGGCGGCCTCTC
GCTGGCCGGCATCATCGGTGCGTCCGGGCTGGCCGAATGGATCGCCAGCAGCCTCGGCGCCTTCGATGCCCTGCCCCTGC
TGGCGATGATCGCGCTGGTGGTGACGGTGATCATCTTCCTCACCGAAATCACCTCCAATACCGCGACTGCAGCGGCCTTC
CTGCCATTGCTCGGTGCGCTCGCCGTGGCCCAGGGGCTGTCCCCGGAAATGCTGGCGATTCCGGCCGCGGTCGCTGCCAG
CTGCGCCTTCATGATGCCGGTCGCGACACCACCCAACGCCATCGTATTCGGCACGGGACAGTTGCCGATCCAGGCGATGA
TCAAGGCCGGCTTCGTGCTCAACCTGTTCGGTGTGCTGCTGGTTTCCCTGCTCTGCTACGGCCTGGTCGGCTGGATATGG
GCGAGCTGA

Upstream 100 bases:

>100_bases
CGAAACGAAACCCCGCCGGCCCTGTCCGCCTAAGTAGGGGCCGCGCGGGTTCAGTCCACACGGCCCCGCTTTCGATAGCG
CAGTTTCGAAGAGGACGAAA

Downstream 100 bases:

>100_bases
CACGCACACAGAAACGAAAAAGCCCAGCATCGAGCTGGGCTTTTTTCTGTCCACCGCAGGCCGAGGATCAGGCCTTGACG
CGGGACTTGTACTCGCCGGT

Product: di- and tricarboxylate transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MAESSQSRGAVLAAWIGLILGPLLLLACILTDPPGGLSEKAWLTVGLAALMAVWWSTEAIPIPATSLLPILLIPLLDIDT
LAKATAPYANPTIFLFLGGFLLGLAMQRWNLHKRIALATLLAVGNQPSRQIAGFMIATAFISMWVSNTATSIMMLPIGLS
VIGLLIAGSEEKEGARFAVALLLGIAYSASVGGIATLIGTPPNALLAAFMRENYDVQIGFGQWMLLGLPLSIGMLVFIWW
SLTRGGFRLAGGDSRGLLEKEMAALGPMSRAEKMVAVVFVLAAAAWIFQPLLADYIDGVNDTSIAMAAAIALFLIPVDLH
KRVFLMDWEQANKAPWGVLLLFGGGLSLAGIIGASGLAEWIASSLGAFDALPLLAMIALVVTVIIFLTEITSNTATAAAF
LPLLGALAVAQGLSPEMLAIPAAVAASCAFMMPVATPPNAIVFGTGQLPIQAMIKAGFVLNLFGVLLVSLLCYGLVGWIW
AS

Sequences:

>Translated_482_residues
MAESSQSRGAVLAAWIGLILGPLLLLACILTDPPGGLSEKAWLTVGLAALMAVWWSTEAIPIPATSLLPILLIPLLDIDT
LAKATAPYANPTIFLFLGGFLLGLAMQRWNLHKRIALATLLAVGNQPSRQIAGFMIATAFISMWVSNTATSIMMLPIGLS
VIGLLIAGSEEKEGARFAVALLLGIAYSASVGGIATLIGTPPNALLAAFMRENYDVQIGFGQWMLLGLPLSIGMLVFIWW
SLTRGGFRLAGGDSRGLLEKEMAALGPMSRAEKMVAVVFVLAAAAWIFQPLLADYIDGVNDTSIAMAAAIALFLIPVDLH
KRVFLMDWEQANKAPWGVLLLFGGGLSLAGIIGASGLAEWIASSLGAFDALPLLAMIALVVTVIIFLTEITSNTATAAAF
LPLLGALAVAQGLSPEMLAIPAAVAASCAFMMPVATPPNAIVFGTGQLPIQAMIKAGFVLNLFGVLLVSLLCYGLVGWIW
AS
>Mature_481_residues
AESSQSRGAVLAAWIGLILGPLLLLACILTDPPGGLSEKAWLTVGLAALMAVWWSTEAIPIPATSLLPILLIPLLDIDTL
AKATAPYANPTIFLFLGGFLLGLAMQRWNLHKRIALATLLAVGNQPSRQIAGFMIATAFISMWVSNTATSIMMLPIGLSV
IGLLIAGSEEKEGARFAVALLLGIAYSASVGGIATLIGTPPNALLAAFMRENYDVQIGFGQWMLLGLPLSIGMLVFIWWS
LTRGGFRLAGGDSRGLLEKEMAALGPMSRAEKMVAVVFVLAAAAWIFQPLLADYIDGVNDTSIAMAAAIALFLIPVDLHK
RVFLMDWEQANKAPWGVLLLFGGGLSLAGIIGASGLAEWIASSLGAFDALPLLAMIALVVTVIIFLTEITSNTATAAAFL
PLLGALAVAQGLSPEMLAIPAAVAASCAFMMPVATPPNAIVFGTGQLPIQAMIKAGFVLNLFGVLLVSLLCYGLVGWIWA
S

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=499, Percent_Identity=36.4729458917836, Blast_Score=264, Evalue=2e-70,
Organism=Homo sapiens, GI4506979, Length=511, Percent_Identity=34.6379647749511, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI301069346, Length=510, Percent_Identity=33.5294117647059, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI31377715, Length=554, Percent_Identity=32.3104693140794, Blast_Score=228, Evalue=7e-60,
Organism=Homo sapiens, GI58761541, Length=521, Percent_Identity=32.0537428023033, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI225637549, Length=560, Percent_Identity=31.6071428571429, Blast_Score=219, Evalue=5e-57,
Organism=Homo sapiens, GI225637552, Length=479, Percent_Identity=34.2379958246347, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI301069349, Length=500, Percent_Identity=32.4, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI219802232, Length=436, Percent_Identity=34.8623853211009, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI301069353, Length=467, Percent_Identity=30.406852248394, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI19923838, Length=346, Percent_Identity=31.2138728323699, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI31795546, Length=332, Percent_Identity=29.5180722891566, Blast_Score=139, Evalue=6e-33,
Organism=Escherichia coli, GI1786986, Length=468, Percent_Identity=26.0683760683761, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1789444, Length=480, Percent_Identity=24.5833333333333, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1786829, Length=490, Percent_Identity=23.265306122449, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71988385, Length=459, Percent_Identity=34.640522875817, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI32565804, Length=444, Percent_Identity=34.9099099099099, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71989118, Length=523, Percent_Identity=30.9751434034417, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI17551790, Length=495, Percent_Identity=29.0909090909091, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI32564681, Length=484, Percent_Identity=28.9256198347107, Blast_Score=182, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6322263, Length=460, Percent_Identity=24.3478260869565, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6319885, Length=456, Percent_Identity=25.4385964912281, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324340, Length=401, Percent_Identity=23.6907730673317, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281362116, Length=499, Percent_Identity=31.8637274549098, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI281362114, Length=499, Percent_Identity=31.6633266533066, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI281362112, Length=499, Percent_Identity=31.6633266533066, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI281366409, Length=512, Percent_Identity=29.296875, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI17737623, Length=512, Percent_Identity=29.296875, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24666468, Length=512, Percent_Identity=29.296875, Blast_Score=183, Evalue=3e-46,
Organism=Drosophila melanogaster, GI45551633, Length=510, Percent_Identity=29.6078431372549, Blast_Score=182, Evalue=4e-46,
Organism=Drosophila melanogaster, GI78706796, Length=490, Percent_Identity=28.3673469387755, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI78706798, Length=490, Percent_Identity=28.3673469387755, Blast_Score=133, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50464; Mature: 50333

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS01271 NA_SULFATE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESSQSRGAVLAAWIGLILGPLLLLACILTDPPGGLSEKAWLTVGLAALMAVWWSTEAI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PIPATSLLPILLIPLLDIDTLAKATAPYANPTIFLFLGGFLLGLAMQRWNLHKRIALATL
CCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVGNQPSRQIAGFMIATAFISMWVSNTATSIMMLPIGLSVIGLLIAGSEEKEGARFAVA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LLLGIAYSASVGGIATLIGTPPNALLAAFMRENYDVQIGFGQWMLLGLPLSIGMLVFIWW
HHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCEEEECCCCEEHHCCHHHHHHHHHHH
SLTRGGFRLAGGDSRGLLEKEMAALGPMSRAEKMVAVVFVLAAAAWIFQPLLADYIDGVN
HHCCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DTSIAMAAAIALFLIPVDLHKRVFLMDWEQANKAPWGVLLLFGGGLSLAGIIGASGLAEW
CHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
IASSLGAFDALPLLAMIALVVTVIIFLTEITSNTATAAAFLPLLGALAVAQGLSPEMLAI
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
PAAVAASCAFMMPVATPPNAIVFGTGQLPIQAMIKAGFVLNLFGVLLVSLLCYGLVGWIW
HHHHHHHHHHHEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AS
CC
>Mature Secondary Structure 
AESSQSRGAVLAAWIGLILGPLLLLACILTDPPGGLSEKAWLTVGLAALMAVWWSTEAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PIPATSLLPILLIPLLDIDTLAKATAPYANPTIFLFLGGFLLGLAMQRWNLHKRIALATL
CCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAVGNQPSRQIAGFMIATAFISMWVSNTATSIMMLPIGLSVIGLLIAGSEEKEGARFAVA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
LLLGIAYSASVGGIATLIGTPPNALLAAFMRENYDVQIGFGQWMLLGLPLSIGMLVFIWW
HHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHCCCCEEEECCCCEEHHCCHHHHHHHHHHH
SLTRGGFRLAGGDSRGLLEKEMAALGPMSRAEKMVAVVFVLAAAAWIFQPLLADYIDGVN
HHCCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DTSIAMAAAIALFLIPVDLHKRVFLMDWEQANKAPWGVLLLFGGGLSLAGIIGASGLAEW
CHHHHHHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
IASSLGAFDALPLLAMIALVVTVIIFLTEITSNTATAAAFLPLLGALAVAQGLSPEMLAI
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
PAAVAASCAFMMPVATPPNAIVFGTGQLPIQAMIKAGFVLNLFGVLLVSLLCYGLVGWIW
HHHHHHHHHHHEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA