Click here to switch to the map view.

The map label for this gene is blrA [H]

Identifier: 145301166

GI number: 145301166

Start: 4649074

End: 4649748

Strand: Direct

Name: blrA [H]

Synonym: ASA_4344

Alternate gene names: 145301166

Gene position: 4649074-4649748 (Clockwise)

Preceding gene: 145301157

Following gene: 145301167

Centisome position: 98.87

GC content: 60.3

Gene sequence:

>675_bases
ATGCAAAAAAAAGTTATCTGGCTGGTGGAAGATGAGGCCAGCATCGCCGACACCCTGATCTATGCGCTGCAAACCGATGG
TTTCGAAGTGGAGTGGTTTCCCCTTGGCCAGCCGCTGTTGACGCGACTGGAACAGACGCGACCCGATTTTCTGATCCTGG
ATGTGGGGCTGCCGGATATCAGCGGCTTCGAGTTATGCAAGCAGGTTCGGGCCCGCTGCGACACCCCCCTGATGTTTCTC
ACCGCCCGCAGCGAGGAGATAGACAGGCTGATAGGGCTGGAAATTGGCGCCGATGATTATGTGGCCAAGCCGTTCTCGCC
ACGGGAGGTGTGTGCCCGGGTACGAGTGATACTGCGCCGCAGCCAGCCGGTCGCCACCCAACCAAGCCAATTGCTGGCAC
TGGATGAGGAGCGGGCCCGCATCAGCTTTCACGGCCAACCGCTGGCCCTCACCCGTTACGAGTACCTGCTGCTCAAGACG
CTGATGCAGGCACCTGGGCGGGTCTACTCTCGTCAGCAGTTGATGGATCTGGTGTGGAGTGGGGCAGAAGAGAGCCTGGA
TCGCACCGTCGACACCCACATCAAGACCATTCGCGCCAAGCTGCGGGAACGTGACGCTGACGCCAACCTGATCCTGACCC
ATCGCGGGCTGGGCTACAGTCTGGAACTGGCATGA

Upstream 100 bases:

>100_bases
TTACGAAATGTTAGCGCCTTTTTCGGAAAAGTAAAACAGCAAATAGGATCCGATTTGGTTCGATGCCAGAATGGGGCAGC
TGATTTGCGACGAGGACGCC

Downstream 100 bases:

>100_bases
GGATCGGCCTGCAGCAAGCATATGGTCTGGCGCCCGGATACAAACGGATAGAACTGGTATGAGAATAGGACTGCAACTGC
TGTGCGGACTGGTGCTGATC

Product: two-component system blr regulon response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MQKKVIWLVEDEASIADTLIYALQTDGFEVEWFPLGQPLLTRLEQTRPDFLILDVGLPDISGFELCKQVRARCDTPLMFL
TARSEEIDRLIGLEIGADDYVAKPFSPREVCARVRVILRRSQPVATQPSQLLALDEERARISFHGQPLALTRYEYLLLKT
LMQAPGRVYSRQQLMDLVWSGAEESLDRTVDTHIKTIRAKLRERDADANLILTHRGLGYSLELA

Sequences:

>Translated_224_residues
MQKKVIWLVEDEASIADTLIYALQTDGFEVEWFPLGQPLLTRLEQTRPDFLILDVGLPDISGFELCKQVRARCDTPLMFL
TARSEEIDRLIGLEIGADDYVAKPFSPREVCARVRVILRRSQPVATQPSQLLALDEERARISFHGQPLALTRYEYLLLKT
LMQAPGRVYSRQQLMDLVWSGAEESLDRTVDTHIKTIRAKLRERDADANLILTHRGLGYSLELA
>Mature_224_residues
MQKKVIWLVEDEASIADTLIYALQTDGFEVEWFPLGQPLLTRLEQTRPDFLILDVGLPDISGFELCKQVRARCDTPLMFL
TARSEEIDRLIGLEIGADDYVAKPFSPREVCARVRVILRRSQPVATQPSQLLALDEERARISFHGQPLALTRYEYLLLKT
LMQAPGRVYSRQQLMDLVWSGAEESLDRTVDTHIKTIRAKLRERDADANLILTHRGLGYSLELA

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=62.9955947136564, Blast_Score=279, Evalue=1e-76,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=43.4389140271493, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=39.0909090909091, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=31.304347826087, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=33.0434782608696, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=34.5132743362832, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=37.5, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=33.7899543378995, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=34.9557522123894, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=33.7899543378995, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.9366515837104, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.0316742081448, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=32.258064516129, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=24.7826086956522, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=33.9130434782609, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25552; Mature: 25552

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKVIWLVEDEASIADTLIYALQTDGFEVEWFPLGQPLLTRLEQTRPDFLILDVGLPDI
CCCEEEEEEECCCHHHHHHHHEEECCCEEEEEEECCHHHHHHHHHCCCCEEEEECCCCCC
SGFELCKQVRARCDTPLMFLTARSEEIDRLIGLEIGADDYVAKPFSPREVCARVRVILRR
CHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHC
SQPVATQPSQLLALDEERARISFHGQPLALTRYEYLLLKTLMQAPGRVYSRQQLMDLVWS
CCCCCCCCHHHEEECCCCCEEEECCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GAEESLDRTVDTHIKTIRAKLRERDADANLILTHRGLGYSLELA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEC
>Mature Secondary Structure
MQKKVIWLVEDEASIADTLIYALQTDGFEVEWFPLGQPLLTRLEQTRPDFLILDVGLPDI
CCCEEEEEEECCCHHHHHHHHEEECCCEEEEEEECCHHHHHHHHHCCCCEEEEECCCCCC
SGFELCKQVRARCDTPLMFLTARSEEIDRLIGLEIGADDYVAKPFSPREVCARVRVILRR
CHHHHHHHHHHHCCCCEEEEEECHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHC
SQPVATQPSQLLALDEERARISFHGQPLALTRYEYLLLKTLMQAPGRVYSRQQLMDLVWS
CCCCCCCCHHHEEECCCCCEEEECCCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GAEESLDRTVDTHIKTIRAKLRERDADANLILTHRGLGYSLELA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]