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The map label for this gene is glpG [H]

Identifier: 145301118

GI number: 145301118

Start: 4585385

End: 4586218

Strand: Direct

Name: glpG [H]

Synonym: ASA_4287

Alternate gene names: 145301118

Gene position: 4585385-4586218 (Clockwise)

Preceding gene: 145301117

Following gene: 145301120

Centisome position: 97.51

GC content: 63.31

Gene sequence:

>834_bases
ATGATCCAGCTGCTGGTGCTCGACAACGCCCGCATGGCGCAAGCCCTGGTGGACTATCTCGCCACCCTCGGCATCTCGTG
CGAGCTGACCCAGTCAGAGCTCGGCGTCTCGGTCTGGCTGGCGGATGAACAACGCCTCGCCCAGGCCCAGCTGGAGGTAA
AGCGATTCCTGGCCGATCCGTCCCATCCCCGCTACATGGAGGCCTCCTGGCAGTCAGGTCAGGCGGATGCCCGCATCGAT
TACAGCAAGGGGATGACGGATCCCGTCACCGATTTCCTCCATCAGGCGGGCCCCCTGACCCTGGTGGTGATCATCGCCTG
TCTGGCCATCTATGCCCTGGATGCCATCGGCCTGCCCATCTTCGACGAGCTGGCGTTCTACCCGACCCTGGCCCAGTTCA
CCGACTGGCAGGCGTGGCGTTACTTCACCCCGGCCTTTATCCACTTCTCGATACTGCACCTGGTGTTCAACCTGCTCTGG
TGGTGGTATCTGGGGGGCCAGATAGAGCAACGCCTCGGCGGCGGCAAGCTGCTGGTCCTGTTGCTAGTGGGGGCGGCCCT
GCCCAATATCGCCGAGTTCTTCGTCAGCGGACCGCTGTTTGGCGGCCTCTCCGGTGTTGTCTATGCTCTGCTGGGCTACT
GCTGGCTGCGCAACAAACTGCAGCCGGCCTGCGGTCTCACCCTGCCACCGGCCCTGATGGGTTTCATGCTGTTCTGGCTG
GTGCTCGGCTTCTTCGACATGCTTGGCACCAGCACCGCCAACATGGCCCATCTGGTGGGCCTGCTGGTAGGTCTGATCCA
AGGCTGGCTGGACAGACACCACCAGCCTGCCTGA

Upstream 100 bases:

>100_bases
CTGCCCAGTACCTGCTGCAGCAGGGGTATGACGAAGTCTACAGCCTGGATGGCGGCTTCGAGGCGTGGCGCCAGGAGTTT
CCCATCGAGGCAGGCGACGC

Downstream 100 bases:

>100_bases
CGGCCGGGCCCCGCCCCGCTCGCAGAAACGAGAACGCCGCCCCGAGGGGCGGCGTTTTTTATGGTCTGCAGCGTTATTGC
TTGAGCAGAGAACTGTCGGT

Product: GlpG protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MIQLLVLDNARMAQALVDYLATLGISCELTQSELGVSVWLADEQRLAQAQLEVKRFLADPSHPRYMEASWQSGQADARID
YSKGMTDPVTDFLHQAGPLTLVVIIACLAIYALDAIGLPIFDELAFYPTLAQFTDWQAWRYFTPAFIHFSILHLVFNLLW
WWYLGGQIEQRLGGGKLLVLLLVGAALPNIAEFFVSGPLFGGLSGVVYALLGYCWLRNKLQPACGLTLPPALMGFMLFWL
VLGFFDMLGTSTANMAHLVGLLVGLIQGWLDRHHQPA

Sequences:

>Translated_277_residues
MIQLLVLDNARMAQALVDYLATLGISCELTQSELGVSVWLADEQRLAQAQLEVKRFLADPSHPRYMEASWQSGQADARID
YSKGMTDPVTDFLHQAGPLTLVVIIACLAIYALDAIGLPIFDELAFYPTLAQFTDWQAWRYFTPAFIHFSILHLVFNLLW
WWYLGGQIEQRLGGGKLLVLLLVGAALPNIAEFFVSGPLFGGLSGVVYALLGYCWLRNKLQPACGLTLPPALMGFMLFWL
VLGFFDMLGTSTANMAHLVGLLVGLIQGWLDRHHQPA
>Mature_277_residues
MIQLLVLDNARMAQALVDYLATLGISCELTQSELGVSVWLADEQRLAQAQLEVKRFLADPSHPRYMEASWQSGQADARID
YSKGMTDPVTDFLHQAGPLTLVVIIACLAIYALDAIGLPIFDELAFYPTLAQFTDWQAWRYFTPAFIHFSILHLVFNLLW
WWYLGGQIEQRLGGGKLLVLLLVGAALPNIAEFFVSGPLFGGLSGVVYALLGYCWLRNKLQPACGLTLPPALMGFMLFWL
VLGFFDMLGTSTANMAHLVGLLVGLIQGWLDRHHQPA

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=275, Percent_Identity=44, Blast_Score=226, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 30771; Mature: 30771

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQLLVLDNARMAQALVDYLATLGISCELTQSELGVSVWLADEQRLAQAQLEVKRFLADP
CEEEEEECCHHHHHHHHHHHHHHCCCEEEEHHHCCEEEEECCHHHHHHHHHHHHHHHCCC
SHPRYMEASWQSGQADARIDYSKGMTDPVTDFLHQAGPLTLVVIIACLAIYALDAIGLPI
CCCCEECCCCCCCCCCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCH
FDELAFYPTLAQFTDWQAWRYFTPAFIHFSILHLVFNLLWWWYLGGQIEQRLGGGKLLVL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHH
LLVGAALPNIAEFFVSGPLFGGLSGVVYALLGYCWLRNKLQPACGLTLPPALMGFMLFWL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VLGFFDMLGTSTANMAHLVGLLVGLIQGWLDRHHQPA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIQLLVLDNARMAQALVDYLATLGISCELTQSELGVSVWLADEQRLAQAQLEVKRFLADP
CEEEEEECCHHHHHHHHHHHHHHCCCEEEEHHHCCEEEEECCHHHHHHHHHHHHHHHCCC
SHPRYMEASWQSGQADARIDYSKGMTDPVTDFLHQAGPLTLVVIIACLAIYALDAIGLPI
CCCCEECCCCCCCCCCCEEECCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCH
FDELAFYPTLAQFTDWQAWRYFTPAFIHFSILHLVFNLLWWWYLGGQIEQRLGGGKLLVL
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHH
LLVGAALPNIAEFFVSGPLFGGLSGVVYALLGYCWLRNKLQPACGLTLPPALMGFMLFWL
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
VLGFFDMLGTSTANMAHLVGLLVGLIQGWLDRHHQPA
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA