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The map label for this gene is norR

Identifier: 145301104

GI number: 145301104

Start: 4570581

End: 4572110

Strand: Direct

Name: norR

Synonym: ASA_4273

Alternate gene names: 145301104

Gene position: 4570581-4572110 (Clockwise)

Preceding gene: 145301098

Following gene: 145301106

Centisome position: 97.2

GC content: 67.97

Gene sequence:

>1530_bases
GTGATTTCAACCGACAGCCTGGCGCGCATCGCCCTCGACCTGCAACTCGGCATCTCCCATCAGGACAGGTTCCACCGTCT
GATCCAGAGCGTGCGCAGCCTGCTGCACTCGGACGCCTCGGCCCTGCTGCGCTACGAGGGGGGCCAGTTCATACCGCTGG
CCATCGACGGCCTGATGCAGGACGTGCTGGGCCGCCGCTTCGCGCTGGCGGACCATCCGCGCATGGAGGCCATCGCCCGT
GCCGGTGACGTGGTGCGCTTCCCCGCCGACAGCAACCTGCCCGACCCCTATGACGGCCTGATCCCGGATCACGACGACTT
CAGGGTGCACGCCTGTGTCGGCCTGCCACTGTTTTCGGATCAGACGCTCATCGGCGCCCTGACCATAGATGGCATGAACC
CGACCCAGTTCGACGGCATCAGCGACGAGGAGCTGCGACTGGTGGGCGCCCTGGCCGCCGCCGCCCTCAGCAACGCCCTG
TTGCTGGAACGGCTCGCCCGCCAGAGCAGCGAACCCCTCGCCCCCTCCACCCAGAATGGGCCGGGCCGGGCCGAGATGAT
TGGCCGCTCCCCGGCCATGGACCGGTTGCGCCACGAGATAAACGTGGTGGCGAGCTCCGAGCTGAACGTGCTGATCCTGG
GGGAGACAGGAGTCGGCAAGGAGCTGATCGCCAAGGCGGTGCATCAGGGCTCACCCCGTGCCAGCGCGCCGCTGGTCTAT
CTCAACTGCGCCGCCCTGCCGGAATCGGTGGCGGAGAGCGAGCTGTTCGGCCACGTGAAGGGGGCTTTCACCGGCGCCAT
TCACAACCGGGCGGGTAAGTTCGAGCTGGCCGACAAGGGCACCCTGTTTCTGGACGAGATCGGCGAACTCTCCCTGTCGC
TGCAGGCCAAGCTGCTGCGGGTGCTGCAATACGGCGATCTGCAGCGCATCGGTGACGACACGCCCCTCAAGGTGAACGTG
CGCATCCTGGCCGCCACCAACCGGGATCTGAAACAGGCGGTGGTCGAGGGGCAATTTCGAAGCGATCTCTACCACCGCTT
GAGCGTCTTCCCGATCCACGCCCCCGCCCTGCGGGAGCGGCCGGACGACATCCCCCTGCTGGCTGGTTATTTTTGCGAAC
GCTGCCGGGTCAGCCTGGGGCTGGAGCGGCTGCGCATCGAGCCCAGGGCGCTGCAACTGCTCGGCAGCTATGACTGGCCG
GGCAACGTGCGGGAGCTGGAGCACGCCATCCACAGAGCCGCCGTGCTGGCGCGGGCCGAGCAGGGCAGTCAGGCCCCCGC
GCTGGAATGCCACCACTTCAACCTGGCGGCCGCCGGCGCCCCCTCATCCAGCCGCATCCCTGTGGAACAGGTAGCGCAGC
AGATGACGGCAGGCATGGGGCTGCGCACGGCTACCGATGCCTTCCAGCTCCAGCTGATCGAGCAGACCCTGGCAGCCCAG
CATGGCAACTGGGCCGCCACCGCCCGAGCGCTGGAGATGGACGGCGGCAACCTGCACCGGCTCGCCAGACGGCTCGGCCT
CAAGCCCTGA

Upstream 100 bases:

>100_bases
AACTCATTGTTTTTATAGAAAACAGATTTCAGGCATTGTCATTTAGACAACTACCACTCATAGTCAAAAACACAAAGACA
CTGTCATTTGGACAATTCTC

Downstream 100 bases:

>100_bases
GACGCACCCCGCCCATAAACAAAATCCCCCTCTGACGAGGGGGGGGTTCGTGGTGCCTATGCGATGACAGGTGCAACGGC
ATGGTCCATCAGTCGCGGGC

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MISTDSLARIALDLQLGISHQDRFHRLIQSVRSLLHSDASALLRYEGGQFIPLAIDGLMQDVLGRRFALADHPRMEAIAR
AGDVVRFPADSNLPDPYDGLIPDHDDFRVHACVGLPLFSDQTLIGALTIDGMNPTQFDGISDEELRLVGALAAAALSNAL
LLERLARQSSEPLAPSTQNGPGRAEMIGRSPAMDRLRHEINVVASSELNVLILGETGVGKELIAKAVHQGSPRASAPLVY
LNCAALPESVAESELFGHVKGAFTGAIHNRAGKFELADKGTLFLDEIGELSLSLQAKLLRVLQYGDLQRIGDDTPLKVNV
RILAATNRDLKQAVVEGQFRSDLYHRLSVFPIHAPALRERPDDIPLLAGYFCERCRVSLGLERLRIEPRALQLLGSYDWP
GNVRELEHAIHRAAVLARAEQGSQAPALECHHFNLAAAGAPSSSRIPVEQVAQQMTAGMGLRTATDAFQLQLIEQTLAAQ
HGNWAATARALEMDGGNLHRLARRLGLKP

Sequences:

>Translated_509_residues
MISTDSLARIALDLQLGISHQDRFHRLIQSVRSLLHSDASALLRYEGGQFIPLAIDGLMQDVLGRRFALADHPRMEAIAR
AGDVVRFPADSNLPDPYDGLIPDHDDFRVHACVGLPLFSDQTLIGALTIDGMNPTQFDGISDEELRLVGALAAAALSNAL
LLERLARQSSEPLAPSTQNGPGRAEMIGRSPAMDRLRHEINVVASSELNVLILGETGVGKELIAKAVHQGSPRASAPLVY
LNCAALPESVAESELFGHVKGAFTGAIHNRAGKFELADKGTLFLDEIGELSLSLQAKLLRVLQYGDLQRIGDDTPLKVNV
RILAATNRDLKQAVVEGQFRSDLYHRLSVFPIHAPALRERPDDIPLLAGYFCERCRVSLGLERLRIEPRALQLLGSYDWP
GNVRELEHAIHRAAVLARAEQGSQAPALECHHFNLAAAGAPSSSRIPVEQVAQQMTAGMGLRTATDAFQLQLIEQTLAAQ
HGNWAATARALEMDGGNLHRLARRLGLKP
>Mature_509_residues
MISTDSLARIALDLQLGISHQDRFHRLIQSVRSLLHSDASALLRYEGGQFIPLAIDGLMQDVLGRRFALADHPRMEAIAR
AGDVVRFPADSNLPDPYDGLIPDHDDFRVHACVGLPLFSDQTLIGALTIDGMNPTQFDGISDEELRLVGALAAAALSNAL
LLERLARQSSEPLAPSTQNGPGRAEMIGRSPAMDRLRHEINVVASSELNVLILGETGVGKELIAKAVHQGSPRASAPLVY
LNCAALPESVAESELFGHVKGAFTGAIHNRAGKFELADKGTLFLDEIGELSLSLQAKLLRVLQYGDLQRIGDDTPLKVNV
RILAATNRDLKQAVVEGQFRSDLYHRLSVFPIHAPALRERPDDIPLLAGYFCERCRVSLGLERLRIEPRALQLLGSYDWP
GNVRELEHAIHRAAVLARAEQGSQAPALECHHFNLAAAGAPSSSRIPVEQVAQQMTAGMGLRTATDAFQLQLIEQTLAAQ
HGNWAATARALEMDGGNLHRLARRLGLKP

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain

Homologues:

Organism=Escherichia coli, GI87082152, Length=507, Percent_Identity=65.6804733727811, Blast_Score=626, Evalue=0.0,
Organism=Escherichia coli, GI1789087, Length=330, Percent_Identity=45.7575757575758, Blast_Score=273, Evalue=1e-74,
Organism=Escherichia coli, GI87082117, Length=310, Percent_Identity=48.0645161290323, Blast_Score=271, Evalue=1e-73,
Organism=Escherichia coli, GI1790437, Length=327, Percent_Identity=46.4831804281346, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1788550, Length=351, Percent_Identity=41.3105413105413, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI1790299, Length=263, Percent_Identity=48.2889733840304, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1788905, Length=335, Percent_Identity=39.4029850746269, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1789233, Length=229, Percent_Identity=45.8515283842795, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=46.7532467532467, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1786524, Length=251, Percent_Identity=43.8247011952191, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1787583, Length=238, Percent_Identity=41.5966386554622, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI1789828, Length=239, Percent_Identity=38.0753138075314, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI87081858, Length=232, Percent_Identity=34.9137931034483, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NORR_AERS4 (A4STH5)

Other databases:

- EMBL:   CP000644
- RefSeq:   YP_001143945.1
- ProteinModelPortal:   A4STH5
- SMR:   A4STH5
- STRING:   A4STH5
- GeneID:   4997187
- GenomeReviews:   CP000644_GR
- KEGG:   asa:ASA_4273
- eggNOG:   COG3604
- HOGENOM:   HBG740884
- OMA:   EARCAIG
- PhylomeDB:   A4STH5
- ProtClustDB:   PRK05022
- BioCyc:   ASAL382245:ASA_4273-MONOMER
- GO:   GO:0005622
- GO:   GO:0006350
- HAMAP:   MF_01314
- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078
- SMART:   SM00382
- SMART:   SM00065

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 55303; Mature: 55303

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00675 SIGMA54_INTERACT_1; PS00676 SIGMA54_INTERACT_2; PS00688 SIGMA54_INTERACT_3; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISTDSLARIALDLQLGISHQDRFHRLIQSVRSLLHSDASALLRYEGGQFIPLAIDGLMQ
CCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHEECCCCEEHHHHHHHHH
DVLGRRFALADHPRMEAIARAGDVVRFPADSNLPDPYDGLIPDHDDFRVHACVGLPLFSD
HHHCCCEECCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCEECC
QTLIGALTIDGMNPTQFDGISDEELRLVGALAAAALSNALLLERLARQSSEPLAPSTQNG
CEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PGRAEMIGRSPAMDRLRHEINVVASSELNVLILGETGVGKELIAKAVHQGSPRASAPLVY
CCHHHHCCCCHHHHHHHHHHHEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEE
LNCAALPESVAESELFGHVKGAFTGAIHNRAGKFELADKGTLFLDEIGELSLSLQAKLLR
EEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHH
VLQYGDLQRIGDDTPLKVNVRILAATNRDLKQAVVEGQFRSDLYHRLSVFPIHAPALRER
HHHHCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHCHHHHHHHHHHEEEEECCHHHHCC
PDDIPLLAGYFCERCRVSLGLERLRIEPRALQLLGSYDWPGNVRELEHAIHRAAVLARAE
CCCCCHHHHHHHHHHHHHHCHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
QGSQAPALECHHFNLAAAGAPSSSRIPVEQVAQQMTAGMGLRTATDAFQLQLIEQTLAAQ
CCCCCCCEEEECEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
HGNWAATARALEMDGGNLHRLARRLGLKP
CCCHHHHEEEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MISTDSLARIALDLQLGISHQDRFHRLIQSVRSLLHSDASALLRYEGGQFIPLAIDGLMQ
CCCCCCHHHEEEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHEECCCCEEHHHHHHHHH
DVLGRRFALADHPRMEAIARAGDVVRFPADSNLPDPYDGLIPDHDDFRVHACVGLPLFSD
HHHCCCEECCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCEECC
QTLIGALTIDGMNPTQFDGISDEELRLVGALAAAALSNALLLERLARQSSEPLAPSTQNG
CEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PGRAEMIGRSPAMDRLRHEINVVASSELNVLILGETGVGKELIAKAVHQGSPRASAPLVY
CCHHHHCCCCHHHHHHHHHHHEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCEEE
LNCAALPESVAESELFGHVKGAFTGAIHNRAGKFELADKGTLFLDEIGELSLSLQAKLLR
EEEHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHH
VLQYGDLQRIGDDTPLKVNVRILAATNRDLKQAVVEGQFRSDLYHRLSVFPIHAPALRER
HHHHCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHCHHHHHHHHHHEEEEECCHHHHCC
PDDIPLLAGYFCERCRVSLGLERLRIEPRALQLLGSYDWPGNVRELEHAIHRAAVLARAE
CCCCCHHHHHHHHHHHHHHCHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
QGSQAPALECHHFNLAAAGAPSSSRIPVEQVAQQMTAGMGLRTATDAFQLQLIEQTLAAQ
CCCCCCCEEEECEEEEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHC
HGNWAATARALEMDGGNLHRLARRLGLKP
CCCHHHHEEEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA