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The map label for this gene is purR [H]

Identifier: 145300955

GI number: 145300955

Start: 4395093

End: 4396100

Strand: Direct

Name: purR [H]

Synonym: ASA_4107

Alternate gene names: 145300955

Gene position: 4395093-4396100 (Clockwise)

Preceding gene: 145300953

Following gene: 145300959

Centisome position: 93.46

GC content: 64.68

Gene sequence:

>1008_bases
ATGAACGACACCCGCAAACGCCGCCCTACACTGCAGGACATAGCCGACCTGACCGGGGTCACCAAGATGACCGTCAGCCG
CTATCTGCGCGATCCCCATGCCGTGGCCGAGGGCACCCGTGAGCGGATCGCCGCCGCAGTGGAAGAGCTGGGCTATATCC
CCAACCGGGCGCCGGACATTCTCTCCAACGCCACCAGCAAGGCGATCGGCATCCTGATCCCCTCCCTCTCCAACCAGGTC
TTCTCCGCCGTGGTGCACGGCATAGAGTCGGTGACCCGGCCTGCCGGCTACCAGACCCTGCTCGCTCACTACGGCTACAG
CCCGGAGCGGGAAGAGGAGCAGGTGGCCTCCCTGCTCTCCTATCACGTGGACGGCCTGATCCTCTCCGACAGCCAGCACA
CGGAGCGCACCCGCAAGATGATCGCCACCGCCGGCATTCCTGTGGTGGAAACCATGGATCTGCCGCAAGCCCCCATCGAC
ATGGTAGTGGGGATGGATCACAGGGCCGCCGCCCGGGCCATGGTAACAGAGATGCTGCGCCGGGGCCGACGCAAGCTGGT
TTACCTGGGGGCGCGGCTCGACGTGCGCACCCAGCTGAGGATGGAGGGTTACTACCAGGCGATGGCCGATTTCGGCCTGA
CAGGTCAGCACCTGCTGACCGAGCAATCCTCCAGCTTCACCCTGGGTGGTCAACTGCTGGATCAGGCGCTGGTGCGCTAT
CCCGACCTCGATGGCCTCTTCTGTACCAATGACGACTTGGCGGTTGGCGCCCTGCTGCAGTGTCAGGCAAAGTGGATACC
CGTCCCCCAGCAGATCGCCATCGCTGGCAGCAACGCCCTCGACATAGGCCATGCCATGACCCCCAAGCTGGCCAGTATCG
TCACACCACGCAAGGAGATAGGCAGTGAGGCGGCGACCATGCTGCTGGCCCGACTCAGCGGCCAGCCACTGCCCGACACC
CGCAAGGATATGGGCTTCTCCCTCTATGTCGGGGAGAGCCTGGGCTGA

Upstream 100 bases:

>100_bases
CCCTTGATCATCCGAGTCATCCTCTACTGATGGCGTCATATGCTGACTTTGTTAAACAAAAACGGTAATGTTACGTGTAA
CATTCCTGCCGGATCCCCAG

Downstream 100 bases:

>100_bases
CGCTTGCGCGAAGGGAGGGTCAAAGCCTGACGGTACGCACGCGAAGCAGTCTGATCCGAAACGCCAGCCGATTTATCCTC
CTGATTCAAAGGCAAAAAAA

Product: Pur operon repressor

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNDTRKRRPTLQDIADLTGVTKMTVSRYLRDPHAVAEGTRERIAAAVEELGYIPNRAPDILSNATSKAIGILIPSLSNQV
FSAVVHGIESVTRPAGYQTLLAHYGYSPEREEEQVASLLSYHVDGLILSDSQHTERTRKMIATAGIPVVETMDLPQAPID
MVVGMDHRAAARAMVTEMLRRGRRKLVYLGARLDVRTQLRMEGYYQAMADFGLTGQHLLTEQSSSFTLGGQLLDQALVRY
PDLDGLFCTNDDLAVGALLQCQAKWIPVPQQIAIAGSNALDIGHAMTPKLASIVTPRKEIGSEAATMLLARLSGQPLPDT
RKDMGFSLYVGESLG

Sequences:

>Translated_335_residues
MNDTRKRRPTLQDIADLTGVTKMTVSRYLRDPHAVAEGTRERIAAAVEELGYIPNRAPDILSNATSKAIGILIPSLSNQV
FSAVVHGIESVTRPAGYQTLLAHYGYSPEREEEQVASLLSYHVDGLILSDSQHTERTRKMIATAGIPVVETMDLPQAPID
MVVGMDHRAAARAMVTEMLRRGRRKLVYLGARLDVRTQLRMEGYYQAMADFGLTGQHLLTEQSSSFTLGGQLLDQALVRY
PDLDGLFCTNDDLAVGALLQCQAKWIPVPQQIAIAGSNALDIGHAMTPKLASIVTPRKEIGSEAATMLLARLSGQPLPDT
RKDMGFSLYVGESLG
>Mature_335_residues
MNDTRKRRPTLQDIADLTGVTKMTVSRYLRDPHAVAEGTRERIAAAVEELGYIPNRAPDILSNATSKAIGILIPSLSNQV
FSAVVHGIESVTRPAGYQTLLAHYGYSPEREEEQVASLLSYHVDGLILSDSQHTERTRKMIATAGIPVVETMDLPQAPID
MVVGMDHRAAARAMVTEMLRRGRRKLVYLGARLDVRTQLRMEGYYQAMADFGLTGQHLLTEQSSSFTLGGQLLDQALVRY
PDLDGLFCTNDDLAVGALLQCQAKWIPVPQQIAIAGSNALDIGHAMTPKLASIVTPRKEIGSEAATMLLARLSGQPLPDT
RKDMGFSLYVGESLG

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=330, Percent_Identity=56.6666666666667, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI1790715, Length=331, Percent_Identity=51.0574018126888, Blast_Score=327, Evalue=9e-91,
Organism=Escherichia coli, GI1790369, Length=317, Percent_Identity=26.813880126183, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=28.5266457680251, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789068, Length=310, Percent_Identity=25.8064516129032, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789202, Length=318, Percent_Identity=26.1006289308176, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787580, Length=324, Percent_Identity=26.5432098765432, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787948, Length=308, Percent_Identity=25.6493506493506, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787906, Length=256, Percent_Identity=26.171875, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790689, Length=319, Percent_Identity=26.3322884012539, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788474, Length=316, Percent_Identity=24.6835443037975, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786268, Length=312, Percent_Identity=28.8461538461538, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786540, Length=316, Percent_Identity=25.9493670886076, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36570; Mature: 36570

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTRKRRPTLQDIADLTGVTKMTVSRYLRDPHAVAEGTRERIAAAVEELGYIPNRAPDI
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LSNATSKAIGILIPSLSNQVFSAVVHGIESVTRPAGYQTLLAHYGYSPEREEEQVASLLS
HHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHH
YHVDGLILSDSQHTERTRKMIATAGIPVVETMDLPQAPIDMVVGMDHRAAARAMVTEMLR
HHHCCEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHH
RGRRKLVYLGARLDVRTQLRMEGYYQAMADFGLTGQHLLTEQSSSFTLGGQLLDQALVRY
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEECHHHHHHHHHHC
PDLDGLFCTNDDLAVGALLQCQAKWIPVPQQIAIAGSNALDIGHAMTPKLASIVTPRKEI
CCCCCEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCHHHH
GSEAATMLLARLSGQPLPDTRKDMGFSLYVGESLG
HHHHHHHHHHHHCCCCCCCHHHHCCEEEEECCCCC
>Mature Secondary Structure
MNDTRKRRPTLQDIADLTGVTKMTVSRYLRDPHAVAEGTRERIAAAVEELGYIPNRAPDI
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LSNATSKAIGILIPSLSNQVFSAVVHGIESVTRPAGYQTLLAHYGYSPEREEEQVASLLS
HHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHH
YHVDGLILSDSQHTERTRKMIATAGIPVVETMDLPQAPIDMVVGMDHRAAARAMVTEMLR
HHHCCEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHH
RGRRKLVYLGARLDVRTQLRMEGYYQAMADFGLTGQHLLTEQSSSFTLGGQLLDQALVRY
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEECHHHHHHHHHHC
PDLDGLFCTNDDLAVGALLQCQAKWIPVPQQIAIAGSNALDIGHAMTPKLASIVTPRKEI
CCCCCEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCHHHHHHCCCHHHH
GSEAATMLLARLSGQPLPDTRKDMGFSLYVGESLG
HHHHHHHHHHHHCCCCCCCHHHHCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]