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The map label for this gene is comF [H]

Identifier: 145300947

GI number: 145300947

Start: 4387322

End: 4388050

Strand: Direct

Name: comF [H]

Synonym: ASA_4099

Alternate gene names: 145300947

Gene position: 4387322-4388050 (Clockwise)

Preceding gene: 145300942

Following gene: 145300948

Centisome position: 93.3

GC content: 60.77

Gene sequence:

>729_bases
ATGTTAAAGCGGCTGCTAGCCAAAGCAAGTCCGATCCTTGGCAGCCATGCCGACTGGCAGGGCAGCTGTCTGCTCTGCCT
GCAAGCTTGTGATAGCCAGCCACTGCTTTGTAGCTGGTGTCGACAAGCCCTGTACCAGTCCTACCCCAGATGCACATTGT
GCGCGGCCCCCTTGCCGGAATACATGGGAGATAAGGAGCTGATCTGCGGCCGCTGCCAGCGCAGGCCACCACCCTGGGAG
CGGTTGCAGGTCATTGGCGACTATCAGGCCCCCTACCCCATGCTCATTCCCCAGCTGAAATACGCCGGCCAGATCCTGCT
GGCGCCACTGCTCGCACGCCTGCTGGCCGATCATCTGAAAAGCGACGAGCTCCCAGAAGTCATCATCCCTGTTCCCCTGC
ACTGGTGGCGGCAGTGGTGGCGCGGCTTCAATCAGGCTGAAGAGATAGCCACCACCCTCAGCCAGATCACCGGCATTCCT
TGCGATAAGCAGTTGCTGAGTCGCACCAAGGCAACCCCGCAACAGACCCGGCTCAGTGCCGGTCAGCGGCGGCGGAATCT
GCGGGGCGCCTTTCACGTTCGCTCCCATCACTATCGGCATGTGGCCCTGCTCGACGATGTGGTAACCACGGGGGCGACGG
CGGGCCAGCTCACCCGCTTACTGCATGAGAGCGGCATCGAAAAAGTGGAAGTGTGGGCCATTTGCCGTACGCTAAAACAT
CTCAAATGA

Upstream 100 bases:

>100_bases
CCCCATCCGTGCAACAGCACCAGATCGGGTCCCTGACCAAATCGCTCTACCGATACGCTCATCTAGACTCAAGATCCCTG
TTCATTCTCTTGGGGTCAGC

Downstream 100 bases:

>100_bases
CCCTAGGTATGTATACCGCAAGCTCGGGTACATAAGGCAGCGATGGAGATGCGTGCCGCCCCGCAAACATCCTCAGCATA
TATCCCGCAGGCTCAGCCAC

Product: competence protein F

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLKRLLAKASPILGSHADWQGSCLLCLQACDSQPLLCSWCRQALYQSYPRCTLCAAPLPEYMGDKELICGRCQRRPPPWE
RLQVIGDYQAPYPMLIPQLKYAGQILLAPLLARLLADHLKSDELPEVIIPVPLHWWRQWWRGFNQAEEIATTLSQITGIP
CDKQLLSRTKATPQQTRLSAGQRRRNLRGAFHVRSHHYRHVALLDDVVTTGATAGQLTRLLHESGIEKVEVWAICRTLKH
LK

Sequences:

>Translated_242_residues
MLKRLLAKASPILGSHADWQGSCLLCLQACDSQPLLCSWCRQALYQSYPRCTLCAAPLPEYMGDKELICGRCQRRPPPWE
RLQVIGDYQAPYPMLIPQLKYAGQILLAPLLARLLADHLKSDELPEVIIPVPLHWWRQWWRGFNQAEEIATTLSQITGIP
CDKQLLSRTKATPQQTRLSAGQRRRNLRGAFHVRSHHYRHVALLDDVVTTGATAGQLTRLLHESGIEKVEVWAICRTLKH
LK
>Mature_242_residues
MLKRLLAKASPILGSHADWQGSCLLCLQACDSQPLLCSWCRQALYQSYPRCTLCAAPLPEYMGDKELICGRCQRRPPPWE
RLQVIGDYQAPYPMLIPQLKYAGQILLAPLLARLLADHLKSDELPEVIIPVPLHWWRQWWRGFNQAEEIATTLSQITGIP
CDKQLLSRTKATPQQTRLSAGQRRRNLRGAFHVRSHHYRHVALLDDVVTTGATAGQLTRLLHESGIEKVEVWAICRTLKH
LK

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=210, Percent_Identity=39.0476190476191, Blast_Score=125, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 27555; Mature: 27555

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRLLAKASPILGSHADWQGSCLLCLQACDSQPLLCSWCRQALYQSYPRCTLCAAPLPE
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECCCCHH
YMGDKELICGRCQRRPPPWERLQVIGDYQAPYPMLIPQLKYAGQILLAPLLARLLADHLK
HCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDELPEVIIPVPLHWWRQWWRGFNQAEEIATTLSQITGIPCDKQLLSRTKATPQQTRLSA
CCCCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
GQRRRNLRGAFHVRSHHYRHVALLDDVVTTGATAGQLTRLLHESGIEKVEVWAICRTLKH
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
LK
CC
>Mature Secondary Structure
MLKRLLAKASPILGSHADWQGSCLLCLQACDSQPLLCSWCRQALYQSYPRCTLCAAPLPE
CHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEECCCCHH
YMGDKELICGRCQRRPPPWERLQVIGDYQAPYPMLIPQLKYAGQILLAPLLARLLADHLK
HCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SDELPEVIIPVPLHWWRQWWRGFNQAEEIATTLSQITGIPCDKQLLSRTKATPQQTRLSA
CCCCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHH
GQRRRNLRGAFHVRSHHYRHVALLDDVVTTGATAGQLTRLLHESGIEKVEVWAICRTLKH
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
LK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]