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The map label for this gene is kefG [H]

Identifier: 145300843

GI number: 145300843

Start: 4280888

End: 4281487

Strand: Direct

Name: kefG [H]

Synonym: ASA_3986

Alternate gene names: 145300843

Gene position: 4280888-4281487 (Clockwise)

Preceding gene: 145300838

Following gene: 145300844

Centisome position: 91.04

GC content: 57.33

Gene sequence:

>600_bases
ATGAAACGCATTCTGGTTATCTTTTCACACCCGGCCCTGCAGAGCTCAAGAGCCAACAAGCAGCTGTTGCAGGCTATCGA
AGAGCTGGAGGGCGTCACAGTTCACGACCTCTATCAGCACTACCCGGACATGTTCATCAATGTAAAACAGGAACAGGCCC
TGCTGTCGGAACACGATATCATCGTCTTTCAACACCCCTTCTACTGGTACTCCTGCCCCGCCATCATGAAGGAGTGGATG
GACCTAGTGCTGGAATACGGCTATGCCTACGGTCCCGAGGCCCATGCCCTCAATGGCAAGCAGTGGCTGAGTGCCATCAC
CACGGGTGGCGCCCCAGAGTCCTATTGCAGCGCAGGCTACAACAGTCGCCCACTGCTCGACTTTTTGCTGCCGTTCCAGC
AAACGGCACAACTGTGCGGCATGACCTGGCTGCCCCCGTTCGTGCTCCACTCCTTTCACAAGATCAAGGATCCGGAGGCA
TTGCGTCGCTGTGGCCAGGATTATCGCCAGCTGTTGTGTGCCCTGCGCGACGAGCAACTGACCCCCGATCAGCTCGCGGG
GCAATCTTATCTGCGGGATCTGCTGGAGGGGCTCTCATGA

Upstream 100 bases:

>100_bases
GGGCCATGGCACTTCTTGATAACGTCACCGCTCAATGCATCTTCTTTTCGCCAGTACTGGTTTTTGCCAGTACCAGGCTC
AGTCTTCAGGTTATGACCCC

Downstream 100 bases:

>100_bases
AACACGGGCAGCTATTTGGCCGACCCCATGAGCCTGACCAGATGTTTAAACGGAGGGCTGGCTGATGGGTCACGGATTAC
TGTTTGATGCGCTTATCTAC

Product: glutathione-regulated potassium-efflux system ancillary protein KefG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKRILVIFSHPALQSSRANKQLLQAIEELEGVTVHDLYQHYPDMFINVKQEQALLSEHDIIVFQHPFYWYSCPAIMKEWM
DLVLEYGYAYGPEAHALNGKQWLSAITTGGAPESYCSAGYNSRPLLDFLLPFQQTAQLCGMTWLPPFVLHSFHKIKDPEA
LRRCGQDYRQLLCALRDEQLTPDQLAGQSYLRDLLEGLS

Sequences:

>Translated_199_residues
MKRILVIFSHPALQSSRANKQLLQAIEELEGVTVHDLYQHYPDMFINVKQEQALLSEHDIIVFQHPFYWYSCPAIMKEWM
DLVLEYGYAYGPEAHALNGKQWLSAITTGGAPESYCSAGYNSRPLLDFLLPFQQTAQLCGMTWLPPFVLHSFHKIKDPEA
LRRCGQDYRQLLCALRDEQLTPDQLAGQSYLRDLLEGLS
>Mature_199_residues
MKRILVIFSHPALQSSRANKQLLQAIEELEGVTVHDLYQHYPDMFINVKQEQALLSEHDIIVFQHPFYWYSCPAIMKEWM
DLVLEYGYAYGPEAHALNGKQWLSAITTGGAPESYCSAGYNSRPLLDFLLPFQQTAQLCGMTWLPPFVLHSFHKIKDPEA
LRRCGQDYRQLLCALRDEQLTPDQLAGQSYLRDLLEGLS

Specific function: Required for full activity of kefB [H]

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=121, Percent_Identity=38.0165289256198, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1789750, Length=148, Percent_Identity=50, Blast_Score=163, Evalue=7e-42,
Organism=Escherichia coli, GI1786231, Length=171, Percent_Identity=46.1988304093567, Blast_Score=139, Evalue=9e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 22862; Mature: 22862

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILVIFSHPALQSSRANKQLLQAIEELEGVTVHDLYQHYPDMFINVKQEQALLSEHDI
CCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHEEECHHHHHHHHHCCE
IVFQHPFYWYSCPAIMKEWMDLVLEYGYAYGPEAHALNGKQWLSAITTGGAPESYCSAGY
EEEECCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCC
NSRPLLDFLLPFQQTAQLCGMTWLPPFVLHSFHKIKDPEALRRCGQDYRQLLCALRDEQL
CCCCHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
TPDQLAGQSYLRDLLEGLS
CHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRILVIFSHPALQSSRANKQLLQAIEELEGVTVHDLYQHYPDMFINVKQEQALLSEHDI
CCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHEEECHHHHHHHHHCCE
IVFQHPFYWYSCPAIMKEWMDLVLEYGYAYGPEAHALNGKQWLSAITTGGAPESYCSAGY
EEEECCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCC
NSRPLLDFLLPFQQTAQLCGMTWLPPFVLHSFHKIKDPEALRRCGQDYRQLLCALRDEQL
CCCCHHHHHHCHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
TPDQLAGQSYLRDLLEGLS
CHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA