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The map label for this gene is exeE [H]

Identifier: 145300644

GI number: 145300644

Start: 4070245

End: 4071750

Strand: Direct

Name: exeE [H]

Synonym: ASA_3776

Alternate gene names: 145300644

Gene position: 4070245-4071750 (Clockwise)

Preceding gene: 145300643

Following gene: 145300645

Centisome position: 86.56

GC content: 62.95

Gene sequence:

>1506_bases
ATGGCGGCGTACCAGCTCGATGGAACGGATCTGCCAGCAGCCCTGCCCGAGCTGCCGTTTGCCTTTGCCCGCAACTTCGG
TGTCATTCTGACCGAACGCCAGGGGACTCCCTTGCTGCTCTGTCGTCAGGGGGGCGCGCCGCAAACCCTGCTGGAAGTCC
GGCGGGTAGCGGGCTGCGCCTTCGAGGTGGAGCAGCTCGAGAACGATGCTTTTGAAGAGTTGCTGATGGCTCACTACCAG
CGCGACTCTTCCGAGGCGCGCCAGCTGATGGAAGATCTCGGCAACGAGATGGACTTCTTTGCCCTGGCCGAAGAGCTGCC
CCAGAGCGAGGATCTGCTGGACGCCGATGACGACGCCCCCATCATTCGCCTCATCAACGCCATGTTGAGCGAGGCGATAA
AAGAGGAGGCGTCCGACATCCATATCGAGACCTTCGAACGGGTGCTGGTCATTCGCTTTCGCATCGATGGCGTGCTGCGG
GAGATACTGCGCCCCCATCGCAAGCTGGCCTCCCTGCTGGTGTCGCGCATCAAGGTCATGTCGCGAATGGACATCGCCGA
GAAGCGGGTCCCGCAGGATGGCCGCATCTCATTGCGTATCGGTGGCCGGGCGGTGGACGTGCGGGTTTCGACCATGCCGT
CCAGCTACGGCGAGCGGGTGGTATTGCGTCTGCTCGACAAGAACAACGTGCGCCTCGAGCTCAAGCAGCTTGGCATGACG
CTGGCCAACCGCAACATCATCAGCGAACTCATTCGCAAGCCCCACGGCATCATATTGGTGACGGGCCCGACCGGTTCGGG
CAAGTCCACCACCCTGTATGCAGCGCTCTCCGAAATCAACTCGCGGGACCGCAACATACTGACGGTGGAAGACCCCATCG
AATATGACCTCGAAGGGGTAGGTCAGACCCAGGTCAACACCAAGGTGGACATGACCTTCGCCCGCGGCCTGCGCGCCATC
TTGCGTCAGGATCCGGACGTGGTGATGGTGGGGGAAATCCGGGATCTGGAAACCGCCCAGATAGCGGTGCAGGCGTCGCT
GACCGGTCACCTGGTGATGTCGACCCTGCACACCAACACTGCCATCGGCGCCATCACCCGAATGCGGGACATGGGGATAG
AGCCTTTCCTGCTCTCCTCATCCTTGCTGGCGGTACTGGCCCAGCGGCTGGTGCGTACCCTCTGTCCGGATTGCCGCACT
CCACGCCCCATCACTGAGCAGGAGCGGGAGGCCATGGGTATGGAGCTGGCGCCAGATCAGCAGGTGTGGCGCCCGGTTGG
CTGCGAGCAGTGCAACCACACCGGCTATCGCGGCCGGACCGGTATTCACGAGCTGGTGGTGATCGACGAGGCGGTGCGCG
AGGCGATCCACAGCGCCAGCGGCGAACTGGCCATAGAGCGGCTGATCCGCGGTCATACCCCCAGCATCCGCCGGGATGGC
ATCGACAAGGTGCTCAAGGGGCAGACCAGCCTTGAAGAAGTGCTGCGGGTGACCCGGGAAGATTGA

Upstream 100 bases:

>100_bases
TGGCCCAGTCGCCCGAGGTACAGAAGCAGATCGAGCTGATGAAGGCCCGCCAGCAGGCGACGGCCGATGGAGCACAGCCG
TTCGTACAGGGTAACAAGTA

Downstream 100 bases:

>100_bases
TGTTCGGTCAGGCAAGCGATTTGAATCGGGATAGCAAGACGTCACAGTGCTAGGGCAGAGGAGCAAAAGTATTGTCAGCA
TTTGAATACAAAGCCCTCGA

Product: general secretion pathway protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 501; Mature: 500

Protein sequence:

>501_residues
MAAYQLDGTDLPAALPELPFAFARNFGVILTERQGTPLLLCRQGGAPQTLLEVRRVAGCAFEVEQLENDAFEELLMAHYQ
RDSSEARQLMEDLGNEMDFFALAEELPQSEDLLDADDDAPIIRLINAMLSEAIKEEASDIHIETFERVLVIRFRIDGVLR
EILRPHRKLASLLVSRIKVMSRMDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSYGERVVLRLLDKNNVRLELKQLGMT
LANRNIISELIRKPHGIILVTGPTGSGKSTTLYAALSEINSRDRNILTVEDPIEYDLEGVGQTQVNTKVDMTFARGLRAI
LRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNTAIGAITRMRDMGIEPFLLSSSLLAVLAQRLVRTLCPDCRT
PRPITEQEREAMGMELAPDQQVWRPVGCEQCNHTGYRGRTGIHELVVIDEAVREAIHSASGELAIERLIRGHTPSIRRDG
IDKVLKGQTSLEEVLRVTRED

Sequences:

>Translated_501_residues
MAAYQLDGTDLPAALPELPFAFARNFGVILTERQGTPLLLCRQGGAPQTLLEVRRVAGCAFEVEQLENDAFEELLMAHYQ
RDSSEARQLMEDLGNEMDFFALAEELPQSEDLLDADDDAPIIRLINAMLSEAIKEEASDIHIETFERVLVIRFRIDGVLR
EILRPHRKLASLLVSRIKVMSRMDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSYGERVVLRLLDKNNVRLELKQLGMT
LANRNIISELIRKPHGIILVTGPTGSGKSTTLYAALSEINSRDRNILTVEDPIEYDLEGVGQTQVNTKVDMTFARGLRAI
LRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNTAIGAITRMRDMGIEPFLLSSSLLAVLAQRLVRTLCPDCRT
PRPITEQEREAMGMELAPDQQVWRPVGCEQCNHTGYRGRTGIHELVVIDEAVREAIHSASGELAIERLIRGHTPSIRRDG
IDKVLKGQTSLEEVLRVTRED
>Mature_500_residues
AAYQLDGTDLPAALPELPFAFARNFGVILTERQGTPLLLCRQGGAPQTLLEVRRVAGCAFEVEQLENDAFEELLMAHYQR
DSSEARQLMEDLGNEMDFFALAEELPQSEDLLDADDDAPIIRLINAMLSEAIKEEASDIHIETFERVLVIRFRIDGVLRE
ILRPHRKLASLLVSRIKVMSRMDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSYGERVVLRLLDKNNVRLELKQLGMTL
ANRNIISELIRKPHGIILVTGPTGSGKSTTLYAALSEINSRDRNILTVEDPIEYDLEGVGQTQVNTKVDMTFARGLRAIL
RQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNTAIGAITRMRDMGIEPFLLSSSLLAVLAQRLVRTLCPDCRTP
RPITEQEREAMGMELAPDQQVWRPVGCEQCNHTGYRGRTGIHELVVIDEAVREAIHSASGELAIERLIRGHTPSIRRDGI
DKVLKGQTSLEEVLRVTRED

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=483, Percent_Identity=57.9710144927536, Blast_Score=566, Evalue=1e-162,
Organism=Escherichia coli, GI1786296, Length=385, Percent_Identity=41.8181818181818, Blast_Score=298, Evalue=7e-82,
Organism=Escherichia coli, GI87082188, Length=195, Percent_Identity=43.5897435897436, Blast_Score=128, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 55885; Mature: 55754

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAYQLDGTDLPAALPELPFAFARNFGVILTERQGTPLLLCRQGGAPQTLLEVRRVAGCA
CCEEECCCCCCCCHHHCCCHHHHCCCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHH
FEVEQLENDAFEELLMAHYQRDSSEARQLMEDLGNEMDFFALAEELPQSEDLLDADDDAP
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCH
IIRLINAMLSEAIKEEASDIHIETFERVLVIRFRIDGVLREILRPHRKLASLLVSRIKVM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRMDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSYGERVVLRLLDKNNVRLELKQLGMT
HHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEHHHHHHH
LANRNIISELIRKPHGIILVTGPTGSGKSTTLYAALSEINSRDRNILTVEDPIEYDLEGV
HHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
GQTQVNTKVDMTFARGLRAILRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNT
CCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHEEEEEHHHHHHHHHHHHHHH
AIGAITRMRDMGIEPFLLSSSLLAVLAQRLVRTLCPDCRTPRPITEQEREAMGMELAPDQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCH
QVWRPVGCEQCNHTGYRGRTGIHELVVIDEAVREAIHSASGELAIERLIRGHTPSIRRDG
HHHCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCC
IDKVLKGQTSLEEVLRVTRED
HHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AAYQLDGTDLPAALPELPFAFARNFGVILTERQGTPLLLCRQGGAPQTLLEVRRVAGCA
CEEECCCCCCCCHHHCCCHHHHCCCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHH
FEVEQLENDAFEELLMAHYQRDSSEARQLMEDLGNEMDFFALAEELPQSEDLLDADDDAP
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCH
IIRLINAMLSEAIKEEASDIHIETFERVLVIRFRIDGVLREILRPHRKLASLLVSRIKVM
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRMDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSYGERVVLRLLDKNNVRLELKQLGMT
HHHHHHHHHCCCCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHHCCCCCEEEHHHHHHH
LANRNIISELIRKPHGIILVTGPTGSGKSTTLYAALSEINSRDRNILTVEDPIEYDLEGV
HHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
GQTQVNTKVDMTFARGLRAILRQDPDVVMVGEIRDLETAQIAVQASLTGHLVMSTLHTNT
CCCCCCCEEHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHEEEEEHHHHHHHHHHHHHHH
AIGAITRMRDMGIEPFLLSSSLLAVLAQRLVRTLCPDCRTPRPITEQEREAMGMELAPDQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCH
QVWRPVGCEQCNHTGYRGRTGIHELVVIDEAVREAIHSASGELAIERLIRGHTPSIRRDG
HHHCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHCC
IDKVLKGQTSLEEVLRVTRED
HHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640836 [H]