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The map label for this gene is exeF [H]

Identifier: 145300645

GI number: 145300645

Start: 4071876

End: 4073042

Strand: Direct

Name: exeF [H]

Synonym: ASA_3777

Alternate gene names: 145300645

Gene position: 4071876-4073042 (Clockwise)

Preceding gene: 145300644

Following gene: 145300646

Centisome position: 86.59

GC content: 62.72

Gene sequence:

>1167_bases
GTGACCGAGGGCGATTCGGCCCGTCAGGTACGCCAGCAACTGCGCGAGCAGGGGCTGACCCCGCTCGAGGTGAACGAGAC
CACAGAGAAGGCAAAGCGGGAAGCGAATCGCTTCGTGCTGTTTCGCCGTGGTGCCTCCACTTCCGAGCTGGCCCTCATTA
CTCGCCAGTTGGCGACCCTGGTGGGTGCAGGCCTGACTATCGAAGAGGCGCTGCGGGCAGTGGCCGAGCAGTGCGAAAAG
GCCCACCTGCGCAGCTTGGTGGCAACCGTGCGCAGCAAGGTCGTAGAAGGCTACTCGCTGGCCGATTCGCTGGGGGCCTT
CCCCCACGTGTTCGATCAGCTGTTCCGCTCCATGGTGGCGGCAGGGGAGAAGTCCGGTCATCTGGAGAAGGTGCTGAACC
GGCTCGCCGACTACACGGAGCAGCGCCAGCATATGCGCACCAAGCTGCTGCAGGCGATGATCTACCCCATAGTCCTCACT
CTGGTGGCGGTCGGGGTCATTTCGATCCTGCTCACTGCCGTGGTACCCAAGGTGGTGGCCCAGTTTGAACACATGGGCCA
GCAGTTGCCTGCGACGACCCGTTTCCTCATCGGCACCAGCGAGCTGATGCAGCATTACGGCCTCTGGTTCCTGCTGCTGC
TGTTCCTGGGGGGCTTTGTCTGGCGCTGGTGGCTGACCGACGAGAAGCGTCGCCGTCACTGGCATCAGGTGATACTGCGC
CTGCCGGTCATCGGCCGGGTCAGCCGTGGTCTCAACACGGCCCGCTTCGCCCGCACCTTGAGCATCCTCAATGCCAGTGC
CGTGCCCTTGCTGGAGGGGATGAAGATCGCCGGCGAAGTGCTCTCCAACGACTTTGCCCGGACGCGCATTGGTGAGGCCA
CCGAACGGGTACGTGAGGGGACCAGCCTGCGCAAGGCGCTGGATGAAACCAGGATTTTTCCGCCCATGATGCTGCACATG
ATCGCCTCCGGCGAGCAGAGCGGCGAGCTCGACAACATGCTGGAGCGGGCGGCGGACAACCAGGACAGGGAATTTGAAAC
CCAGGTTAATATCGCCCTCGGCGTGTTCGAGCCCCTGCTGGTGGTCTCCATGGCCGGGGTTGTGCTGTTTATCGTGATGT
CGATCCTGCAGCCGATCCTCGAGCTCAACAATATGGTCAATCTCTGA

Upstream 100 bases:

>100_bases
TCGGGATAGCAAGACGTCACAGTGCTAGGGCAGAGGAGCAAAAGTATTGTCAGCATTTGAATACAAAGCCCTCGACAGCA
AGGGGCGCCAGAAGCAGGGG

Downstream 100 bases:

>100_bases
TGGCCTGCGCCATCTCATTTCGTTAGGGAGTAAGTCATGCAAAAGCGTCGTCAATCCGGTTTTACCCTGCTGGAAGTCAT
GGTGGTCATAGTGATCCTCG

Product: general secretion pathway protein F

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTEGDSARQVRQQLREQGLTPLEVNETTEKAKREANRFVLFRRGASTSELALITRQLATLVGAGLTIEEALRAVAEQCEK
AHLRSLVATVRSKVVEGYSLADSLGAFPHVFDQLFRSMVAAGEKSGHLEKVLNRLADYTEQRQHMRTKLLQAMIYPIVLT
LVAVGVISILLTAVVPKVVAQFEHMGQQLPATTRFLIGTSELMQHYGLWFLLLLFLGGFVWRWWLTDEKRRRHWHQVILR
LPVIGRVSRGLNTARFARTLSILNASAVPLLEGMKIAGEVLSNDFARTRIGEATERVREGTSLRKALDETRIFPPMMLHM
IASGEQSGELDNMLERAADNQDREFETQVNIALGVFEPLLVVSMAGVVLFIVMSILQPILELNNMVNL

Sequences:

>Translated_388_residues
MTEGDSARQVRQQLREQGLTPLEVNETTEKAKREANRFVLFRRGASTSELALITRQLATLVGAGLTIEEALRAVAEQCEK
AHLRSLVATVRSKVVEGYSLADSLGAFPHVFDQLFRSMVAAGEKSGHLEKVLNRLADYTEQRQHMRTKLLQAMIYPIVLT
LVAVGVISILLTAVVPKVVAQFEHMGQQLPATTRFLIGTSELMQHYGLWFLLLLFLGGFVWRWWLTDEKRRRHWHQVILR
LPVIGRVSRGLNTARFARTLSILNASAVPLLEGMKIAGEVLSNDFARTRIGEATERVREGTSLRKALDETRIFPPMMLHM
IASGEQSGELDNMLERAADNQDREFETQVNIALGVFEPLLVVSMAGVVLFIVMSILQPILELNNMVNL
>Mature_387_residues
TEGDSARQVRQQLREQGLTPLEVNETTEKAKREANRFVLFRRGASTSELALITRQLATLVGAGLTIEEALRAVAEQCEKA
HLRSLVATVRSKVVEGYSLADSLGAFPHVFDQLFRSMVAAGEKSGHLEKVLNRLADYTEQRQHMRTKLLQAMIYPIVLTL
VAVGVISILLTAVVPKVVAQFEHMGQQLPATTRFLIGTSELMQHYGLWFLLLLFLGGFVWRWWLTDEKRRRHWHQVILRL
PVIGRVSRGLNTARFARTLSILNASAVPLLEGMKIAGEVLSNDFARTRIGEATERVREGTSLRKALDETRIFPPMMLHMI
ASGEQSGELDNMLERAADNQDREFETQVNIALGVFEPLLVVSMAGVVLFIVMSILQPILELNNMVNL

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=387, Percent_Identity=46.5116279069767, Blast_Score=352, Evalue=3e-98,
Organism=Escherichia coli, GI1786295, Length=379, Percent_Identity=25.5936675461741, Blast_Score=124, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR011850
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 43534; Mature: 43402

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGDSARQVRQQLREQGLTPLEVNETTEKAKREANRFVLFRRGASTSELALITRQLATL
CCCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHH
VGAGLTIEEALRAVAEQCEKAHLRSLVATVRSKVVEGYSLADSLGAFPHVFDQLFRSMVA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AGEKSGHLEKVLNRLADYTEQRQHMRTKLLQAMIYPIVLTLVAVGVISILLTAVVPKVVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFEHMGQQLPATTRFLIGTSELMQHYGLWFLLLLFLGGFVWRWWLTDEKRRRHWHQVILR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LPVIGRVSRGLNTARFARTLSILNASAVPLLEGMKIAGEVLSNDFARTRIGEATERVREG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLRKALDETRIFPPMMLHMIASGEQSGELDNMLERAADNQDREFETQVNIALGVFEPLL
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VVSMAGVVLFIVMSILQPILELNNMVNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEGDSARQVRQQLREQGLTPLEVNETTEKAKREANRFVLFRRGASTSELALITRQLATL
CCCCHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHH
VGAGLTIEEALRAVAEQCEKAHLRSLVATVRSKVVEGYSLADSLGAFPHVFDQLFRSMVA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AGEKSGHLEKVLNRLADYTEQRQHMRTKLLQAMIYPIVLTLVAVGVISILLTAVVPKVVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QFEHMGQQLPATTRFLIGTSELMQHYGLWFLLLLFLGGFVWRWWLTDEKRRRHWHQVILR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LPVIGRVSRGLNTARFARTLSILNASAVPLLEGMKIAGEVLSNDFARTRIGEATERVREG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSLRKALDETRIFPPMMLHMIASGEQSGELDNMLERAADNQDREFETQVNIALGVFEPLL
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VVSMAGVVLFIVMSILQPILELNNMVNL
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1640836 [H]