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The map label for this gene is exeD [H]

Identifier: 145300643

GI number: 145300643

Start: 4068209

End: 4070245

Strand: Direct

Name: exeD [H]

Synonym: ASA_3775

Alternate gene names: 145300643

Gene position: 4068209-4070245 (Clockwise)

Preceding gene: 145300642

Following gene: 145300644

Centisome position: 86.51

GC content: 59.7

Gene sequence:

>2037_bases
ATGATAAATAAAGGGAAGAGCTGGCGTCTTGCCACGGTCGCGGCGGCGCTGATGATGGCAGGCTCTGCCTGGGCCACCGA
GTATTCTGCCAGCTTCAAGAATGCCGACATCGAAGAGTTCATCAACACGGTCGGCAAGAACCTGAGCAAGACCATCATCA
TAGAGCCTTCGGTACGCGGCAAGATCAACGTCCGCAGCTACGACTTGCTCAACGAAGAGCAGTATTACCAGTTCTTCCTG
AGCGTGCTCGACGTCTATGGCTTTGCCGTTGTGCCCATGGATAACGGCGTGCTCAAGGTTGTGCGCTCCAAGGATGCCAA
GACCTCGGCCATCCCTGTGGTGGATGAGACCAACCCGGGCATTGGCGACGAGATGGTGACCCGGGTGGTGCCGGTGCGCA
ATGTCTCGGTACGTGAACTGGCCCCCTTGCTGCGTCAGCTCAACGACAACGCCGGTGGCGGCAACGTGGTGCATTACGAT
CCCTCCAACGTGCTGCTTATCACGGGCCGTGCCGCCGTGGTCAACCGTCTGGTGGAAGTGGTGCGCCGGGTCGACAAGGC
GGGCGATCAGGAAGTGGACATCATCAAGTTGAGATATGCCTCCGCCGGCGAGATGGTACGACTGGTGACCAACCTCAACA
AGGATGGCAACACCCAGGGCGGCAACACTTCCCTGCTGCTGGCGCCCAAGGTAGTGGCCGATGAGCGCACCAATTCCGTG
GTGGTCAGTGGTGAACCCAAGGCGCGGGCTCGCATCATACAGATGGTGCGCCAGCTCGACCGCGACCTGCAGAGCCAGGG
CAATACCCGGGTCTTCTATCTCAAATATGGCAAGGCCAAGGACATGGTGGAGGTGCTCAAGGGCGTCAGCACCAGCATAG
AAGCGGACAAGAAGGGGGGCGGCACCACGGCCGGTGGCGGCAATGCCAGCATAGGTGGTGGCAAGCTGGCCATCTCGGCT
GATGAGACCACCAATGCGCTGGTCATCACGGCCCAGCCGGATGTGATGGCCGAGCTGGAGCAGGTGGTTGCCAAGCTGGA
TATCCGCCGTGCTCAGGTGCTGGTGGAGGCGATCATCGTCGAAATCGCCGACGGCGACGGTCTCAACCTGGGGGTTCAGT
GGGCCAATACCAACGGTGGCGGTACCCAGTTTACCGATACCAACCTGCCTATTGGCTCGGTGGCCATTGCCGCCAAGGAT
TACAACGAGAATGGCACCACCACGGGTCTTGCCGATCTGGCGAAGGGCTTTAACGGCATGGCCGCCGGTTTCTACCATGG
CAACTGGGCTGCGCTGGTAACGGCGCTCTCCACCAGCACCAAGAGCGATATTCTCTCCACCCCGAGTATCGTCACCATGG
ACAACAAGGAAGCCTCCTTCAACGTGGGTCAGGAAGTGCCGGTGCAGAGTGGTTCCCAGAGTTCCACCACCAGCGATCAG
GTGTTCAACACCATAGAGCGCAAGACGGTGGGCACCAAGTTGACGGTGACGCCGCAGATAAACGAAGGGGACTCAGTGCT
GCTCAATATCGAGCAGGAGGTCTCCAGCGTGGCGCAGAAACAGGCGACCGGTACTGCCGATCTGGGCCCCACCTTCGATA
CTCGCACCATCAAGAACGCCGTGCTGGTCAAAAGCGGCGAAACCGTGGTGCTGGGCGGTCTGATGGATGAGCAGACTCAG
GAGAAGGTTTCCAAGGTGCCTTTGCTGGGCGACATTCCTGTGCTGGGCTACCTGTTCCGCTCTACCAACAACACCACCTC
CAAGCGCAACCTGATGGTCTTTATCCGCCCCACCATATTGCGCGATGCCCACGTCTACTCGGGGATATCCAGCAACAAGT
ACACCATGTTCCGGGCCGAGCAGCTGGACGCTGCCGCTCAGGAGAGCTATCTCACCTCACCGAAACGTCAGGTGCTGCCC
GAATATGGTCAGGATGTGGCCCAGTCGCCCGAGGTACAGAAGCAGATCGAGCTGATGAAGGCCCGCCAGCAGGCGACGGC
CGATGGAGCACAGCCGTTCGTACAGGGTAACAAGTAA

Upstream 100 bases:

>100_bases
GGCAGGCGCCACGGAAATGACCGTCACCGTCGAACGGCAGGGACAGCTCTACGACGTTTATGTCGGCTTGTCAGAATAAT
GATTTGGAGTAGCACCAAGA

Downstream 100 bases:

>100_bases
TGGCGGCGTACCAGCTCGATGGAACGGATCTGCCAGCAGCCCTGCCCGAGCTGCCGTTTGCCTTTGCCCGCAACTTCGGT
GTCATTCTGACCGAACGCCA

Product: general secretion pathway protein D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 678

Protein sequence:

>678_residues
MINKGKSWRLATVAAALMMAGSAWATEYSASFKNADIEEFINTVGKNLSKTIIIEPSVRGKINVRSYDLLNEEQYYQFFL
SVLDVYGFAVVPMDNGVLKVVRSKDAKTSAIPVVDETNPGIGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYD
PSNVLLITGRAAVVNRLVEVVRRVDKAGDQEVDIIKLRYASAGEMVRLVTNLNKDGNTQGGNTSLLLAPKVVADERTNSV
VVSGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKDMVEVLKGVSTSIEADKKGGGTTAGGGNASIGGGKLAISA
DETTNALVITAQPDVMAELEQVVAKLDIRRAQVLVEAIIVEIADGDGLNLGVQWANTNGGGTQFTDTNLPIGSVAIAAKD
YNENGTTTGLADLAKGFNGMAAGFYHGNWAALVTALSTSTKSDILSTPSIVTMDNKEASFNVGQEVPVQSGSQSSTTSDQ
VFNTIERKTVGTKLTVTPQINEGDSVLLNIEQEVSSVAQKQATGTADLGPTFDTRTIKNAVLVKSGETVVLGGLMDEQTQ
EKVSKVPLLGDIPVLGYLFRSTNNTTSKRNLMVFIRPTILRDAHVYSGISSNKYTMFRAEQLDAAAQESYLTSPKRQVLP
EYGQDVAQSPEVQKQIELMKARQQATADGAQPFVQGNK

Sequences:

>Translated_678_residues
MINKGKSWRLATVAAALMMAGSAWATEYSASFKNADIEEFINTVGKNLSKTIIIEPSVRGKINVRSYDLLNEEQYYQFFL
SVLDVYGFAVVPMDNGVLKVVRSKDAKTSAIPVVDETNPGIGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYD
PSNVLLITGRAAVVNRLVEVVRRVDKAGDQEVDIIKLRYASAGEMVRLVTNLNKDGNTQGGNTSLLLAPKVVADERTNSV
VVSGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKDMVEVLKGVSTSIEADKKGGGTTAGGGNASIGGGKLAISA
DETTNALVITAQPDVMAELEQVVAKLDIRRAQVLVEAIIVEIADGDGLNLGVQWANTNGGGTQFTDTNLPIGSVAIAAKD
YNENGTTTGLADLAKGFNGMAAGFYHGNWAALVTALSTSTKSDILSTPSIVTMDNKEASFNVGQEVPVQSGSQSSTTSDQ
VFNTIERKTVGTKLTVTPQINEGDSVLLNIEQEVSSVAQKQATGTADLGPTFDTRTIKNAVLVKSGETVVLGGLMDEQTQ
EKVSKVPLLGDIPVLGYLFRSTNNTTSKRNLMVFIRPTILRDAHVYSGISSNKYTMFRAEQLDAAAQESYLTSPKRQVLP
EYGQDVAQSPEVQKQIELMKARQQATADGAQPFVQGNK
>Mature_678_residues
MINKGKSWRLATVAAALMMAGSAWATEYSASFKNADIEEFINTVGKNLSKTIIIEPSVRGKINVRSYDLLNEEQYYQFFL
SVLDVYGFAVVPMDNGVLKVVRSKDAKTSAIPVVDETNPGIGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYD
PSNVLLITGRAAVVNRLVEVVRRVDKAGDQEVDIIKLRYASAGEMVRLVTNLNKDGNTQGGNTSLLLAPKVVADERTNSV
VVSGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKDMVEVLKGVSTSIEADKKGGGTTAGGGNASIGGGKLAISA
DETTNALVITAQPDVMAELEQVVAKLDIRRAQVLVEAIIVEIADGDGLNLGVQWANTNGGGTQFTDTNLPIGSVAIAAKD
YNENGTTTGLADLAKGFNGMAAGFYHGNWAALVTALSTSTKSDILSTPSIVTMDNKEASFNVGQEVPVQSGSQSSTTSDQ
VFNTIERKTVGTKLTVTPQINEGDSVLLNIEQEVSSVAQKQATGTADLGPTFDTRTIKNAVLVKSGETVVLGGLMDEQTQ
EKVSKVPLLGDIPVLGYLFRSTNNTTSKRNLMVFIRPTILRDAHVYSGISSNKYTMFRAEQLDAAAQESYLTSPKRQVLP
EYGQDVAQSPEVQKQIELMKARQQATADGAQPFVQGNK

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI87082242, Length=623, Percent_Identity=56.3402889245586, Blast_Score=681, Evalue=0.0,
Organism=Escherichia coli, GI1789793, Length=310, Percent_Identity=30.9677419354839, Blast_Score=105, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR013356
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 72769; Mature: 72769

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKGKSWRLATVAAALMMAGSAWATEYSASFKNADIEEFINTVGKNLSKTIIIEPSVRG
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECCCCCC
KINVRSYDLLNEEQYYQFFLSVLDVYGFAVVPMDNGVLKVVRSKDAKTSAIPVVDETNPG
EEEEEEECCCCHHHHHHHHHHHHHHHCEEEEECCCCEEEEEECCCCCCCCCCEEECCCCC
IGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYDPSNVLLITGRAAVVNRLVEV
CCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHH
VRRVDKAGDQEVDIIKLRYASAGEMVRLVTNLNKDGNTQGGNTSLLLAPKVVADERTNSV
HHHHHHCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEECHHHCCCCCCEE
VVSGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKDMVEVLKGVSTSIEADKKGG
EEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCC
GTTAGGGNASIGGGKLAISADETTNALVITAQPDVMAELEQVVAKLDIRRAQVLVEAIIV
CCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIADGDGLNLGVQWANTNGGGTQFTDTNLPIGSVAIAAKDYNENGTTTGLADLAKGFNGM
EECCCCCCEEEEEEECCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCC
AAGFYHGNWAALVTALSTSTKSDILSTPSIVTMDNKEASFNVGQEVPVQSGSQSSTTSDQ
EEEEECCCHHHHHHHHHCCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHH
VFNTIERKTVGTKLTVTPQINEGDSVLLNIEQEVSSVAQKQATGTADLGPTFDTRTIKNA
HHHHHHHHHCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHCCE
VLVKSGETVVLGGLMDEQTQEKVSKVPLLGDIPVLGYLFRSTNNTTSKRNLMVFIRPTIL
EEEECCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEECHHH
RDAHVYSGISSNKYTMFRAEQLDAAAQESYLTSPKRQVLPEYGQDVAQSPEVQKQIELMK
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHCHHHHCCCHHHHHHHHHH
ARQQATADGAQPFVQGNK
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MINKGKSWRLATVAAALMMAGSAWATEYSASFKNADIEEFINTVGKNLSKTIIIEPSVRG
CCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEECCCCCC
KINVRSYDLLNEEQYYQFFLSVLDVYGFAVVPMDNGVLKVVRSKDAKTSAIPVVDETNPG
EEEEEEECCCCHHHHHHHHHHHHHHHCEEEEECCCCEEEEEECCCCCCCCCCEEECCCCC
IGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYDPSNVLLITGRAAVVNRLVEV
CCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEECCHHHHHHHHHH
VRRVDKAGDQEVDIIKLRYASAGEMVRLVTNLNKDGNTQGGNTSLLLAPKVVADERTNSV
HHHHHHCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEEEEECHHHCCCCCCEE
VVSGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKDMVEVLKGVSTSIEADKKGG
EEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHCCCCCCCCCCCCC
GTTAGGGNASIGGGKLAISADETTNALVITAQPDVMAELEQVVAKLDIRRAQVLVEAIIV
CCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIADGDGLNLGVQWANTNGGGTQFTDTNLPIGSVAIAAKDYNENGTTTGLADLAKGFNGM
EECCCCCCEEEEEEECCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCC
AAGFYHGNWAALVTALSTSTKSDILSTPSIVTMDNKEASFNVGQEVPVQSGSQSSTTSDQ
EEEEECCCHHHHHHHHHCCCHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHH
VFNTIERKTVGTKLTVTPQINEGDSVLLNIEQEVSSVAQKQATGTADLGPTFDTRTIKNA
HHHHHHHHHCCCEEEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHHCCE
VLVKSGETVVLGGLMDEQTQEKVSKVPLLGDIPVLGYLFRSTNNTTSKRNLMVFIRPTIL
EEEECCCEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEECHHH
RDAHVYSGISSNKYTMFRAEQLDAAAQESYLTSPKRQVLPEYGQDVAQSPEVQKQIELMK
HHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHCHHHHCCCHHHHHHHHHH
ARQQATADGAQPFVQGNK
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1640836 [H]