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The map label for this gene is yheS [H]

Identifier: 145300403

GI number: 145300403

Start: 3819271

End: 3821181

Strand: Direct

Name: yheS [H]

Synonym: ASA_3528

Alternate gene names: 145300403

Gene position: 3819271-3821181 (Clockwise)

Preceding gene: 145300401

Following gene: 145300404

Centisome position: 81.22

GC content: 62.59

Gene sequence:

>1911_bases
ATGATAGTTGCCAGTCAAATCGAACTGATCCGCGGCGGCCGCAAGCTGCTGGACAACGCTTCCGCCACCATTCACCCGGG
CCACAAGGTGGGCCTGGTGGGTAAAAATGGCAGTGGCAAGTCCACCTTTTTTGCACTGGTACGGGGCGAGCTTGCCATCG
ACAGCGGCAGCTTCAGCCTGCCCGCCGGCTGGCAGATTGCCGGTGTGGCCCAGGAGACGCCGGCGCTGGACTGCTCTGCG
CTGGACTACGTGATCGACGGCGACAAGGAGTTCCGCTCACTGGAAGCCCAGCTGGCCCAGGCCGAGCTGGATGACAACGG
CATACTGGTGGCCGAGCTGCACGGCAAGCTCGATACCATAGGCGCTTACAGCATTCGGGCCCGCGCCGCCGAGCTGCTGC
ACGGTCTGGGTTTTGGCGACGAGCAACTCGGCTCGCCGGTACGCAGCTTCTCCGGTGGCTGGCGCATGCGCCTGAACCTG
GCCCAGGCCCTGCTCTGCCGCTCCGACCTGTTGCTGCTCGATGAACCGACCAACCACCTGGATCTCGATGCCGTCATCTG
GCTGGAGAAGTGGCTCAAGGGCTATCAGGGCACGCTCGTGCTGATTTCGCACGACCGCGACTTCCTCGACTCTGTCATCA
GCCGCATCATCCACATCGAGAACGGCAAGCTCAACGAATACACCGGCGGCTACTCCGACTTCGAACTGCAACGTGCCGAG
CAGCTGGCCCAGCAGCAGTCCATGTACGAGAAGCAGCAGCGGGAGGTGTCCCACATGCAGGCCTATGTGGACCGCTTCCG
CTACAAAGCCTCCAAGGCCCGTCAGGCCCAGAGTCGCCTCAAAGCCATGGAGCGGATGGAGAAACTCCTGCCCGCCCACG
CCGATTCCGAGTTCAGCTTCGAGTTTCGCGAGCCGTCGGCCTTGCCGACCCCGCTCATCGCCATGGAGAACCTCTGCGCC
GGTTACGGCGACAAGGTGATCCTGGAGAAGATAAAGATGAACCTGGTGCCGGGTTCACGCATCGGCCTGCTCGGTCGCAA
CGGCGCCGGCAAGTCCACCTTCATCAAGATGCTGTCGGGCACCAATCCGCCCCTGTCGGGCAAGCTGGAAGTGAGCGCGG
GTGTCAGCATCGGCTACTTCGCCCAGCATCAGCTCGAAACCCTGCGCCTCGACGATACCCCGCTCGATCACCTGGCCCGC
CTCGCGCCGGACAAGTCCGAGCAGGAGCTGCGCAACTATCTGGGCAGTTTTGGTTTTCACGGTGACAAGGCGCTGGACAA
AGTTGCCCCCTTCTCCGGCGGCGAAAAGGCACGGCTGGTACTGGCACTCGTCACCTGGCAAAAACCGAACCTCTTGCTGC
TGGATGAACCGACCAACCACCTGGATCTGGAGATGCGCCACGCCCTGACCATGGCGCTGCAAGGCTTCGAGGGCGCCATG
GTGGTGGTCTCTCACGACCGGCACCTGCTGCGCACCACCACGGATGACTTCTATCTGGTGCACGGTGGCCGGGTCGAAGC
CTTCGATGGCGATCTGGACGACTACCACAAGTGGCTGGGCGAGCAGGAGAAAGAGGCCAACGCCAAGCCCAGCGACGGCA
TCATCTCAGCCAACTCGGCACTGGCGCGCAAGGATCAGAAGCGGCGCGAGGCGGAATTCCGCCAGCAGACCCGCCCCCTG
CGCCAGAAGCTGGAGAAGCTGGAAGCCAGCATGGCGAAATTGCAGACCCGATTGGCGGCCGTGGAAGAGCAGCTGGCCGA
CCCCGCCATCTATGAAGAGGCGGCCAAGAACAAGCTCTCGGAGCTGCTCAAATCCCAAGGGCCCATCAAGGAAGAGCTGG
ATGGTGTCGAGCAGGAATGGATGAGCCTCTCTGAAGAGCTGGAAACCATGGAGCAGACCTTCCTTGCATGA

Upstream 100 bases:

>100_bases
CAGCCAGTCGCCCGTCCTTAGCCCAAGTGCAAATCTGCGCCATTTCACGTAAGATCCGCGCCAGATTTTCTCCTCCATTT
TGAGCAAGCAGACCCCACCC

Downstream 100 bases:

>100_bases
TGACCCGCTGATAGCGACCGAGCGGGTCGCCGTACACGAATTGCCAACGCCCATCGGCTTCTGGCACTGGAGCGGCAAGG
TCTATGGCGAGCGCAGCCAG

Product: ABC-type transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MIVASQIELIRGGRKLLDNASATIHPGHKVGLVGKNGSGKSTFFALVRGELAIDSGSFSLPAGWQIAGVAQETPALDCSA
LDYVIDGDKEFRSLEAQLAQAELDDNGILVAELHGKLDTIGAYSIRARAAELLHGLGFGDEQLGSPVRSFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVIWLEKWLKGYQGTLVLISHDRDFLDSVISRIIHIENGKLNEYTGGYSDFELQRAE
QLAQQQSMYEKQQREVSHMQAYVDRFRYKASKARQAQSRLKAMERMEKLLPAHADSEFSFEFREPSALPTPLIAMENLCA
GYGDKVILEKIKMNLVPGSRIGLLGRNGAGKSTFIKMLSGTNPPLSGKLEVSAGVSIGYFAQHQLETLRLDDTPLDHLAR
LAPDKSEQELRNYLGSFGFHGDKALDKVAPFSGGEKARLVLALVTWQKPNLLLLDEPTNHLDLEMRHALTMALQGFEGAM
VVVSHDRHLLRTTTDDFYLVHGGRVEAFDGDLDDYHKWLGEQEKEANAKPSDGIISANSALARKDQKRREAEFRQQTRPL
RQKLEKLEASMAKLQTRLAAVEEQLADPAIYEEAAKNKLSELLKSQGPIKEELDGVEQEWMSLSEELETMEQTFLA

Sequences:

>Translated_636_residues
MIVASQIELIRGGRKLLDNASATIHPGHKVGLVGKNGSGKSTFFALVRGELAIDSGSFSLPAGWQIAGVAQETPALDCSA
LDYVIDGDKEFRSLEAQLAQAELDDNGILVAELHGKLDTIGAYSIRARAAELLHGLGFGDEQLGSPVRSFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVIWLEKWLKGYQGTLVLISHDRDFLDSVISRIIHIENGKLNEYTGGYSDFELQRAE
QLAQQQSMYEKQQREVSHMQAYVDRFRYKASKARQAQSRLKAMERMEKLLPAHADSEFSFEFREPSALPTPLIAMENLCA
GYGDKVILEKIKMNLVPGSRIGLLGRNGAGKSTFIKMLSGTNPPLSGKLEVSAGVSIGYFAQHQLETLRLDDTPLDHLAR
LAPDKSEQELRNYLGSFGFHGDKALDKVAPFSGGEKARLVLALVTWQKPNLLLLDEPTNHLDLEMRHALTMALQGFEGAM
VVVSHDRHLLRTTTDDFYLVHGGRVEAFDGDLDDYHKWLGEQEKEANAKPSDGIISANSALARKDQKRREAEFRQQTRPL
RQKLEKLEASMAKLQTRLAAVEEQLADPAIYEEAAKNKLSELLKSQGPIKEELDGVEQEWMSLSEELETMEQTFLA
>Mature_636_residues
MIVASQIELIRGGRKLLDNASATIHPGHKVGLVGKNGSGKSTFFALVRGELAIDSGSFSLPAGWQIAGVAQETPALDCSA
LDYVIDGDKEFRSLEAQLAQAELDDNGILVAELHGKLDTIGAYSIRARAAELLHGLGFGDEQLGSPVRSFSGGWRMRLNL
AQALLCRSDLLLLDEPTNHLDLDAVIWLEKWLKGYQGTLVLISHDRDFLDSVISRIIHIENGKLNEYTGGYSDFELQRAE
QLAQQQSMYEKQQREVSHMQAYVDRFRYKASKARQAQSRLKAMERMEKLLPAHADSEFSFEFREPSALPTPLIAMENLCA
GYGDKVILEKIKMNLVPGSRIGLLGRNGAGKSTFIKMLSGTNPPLSGKLEVSAGVSIGYFAQHQLETLRLDDTPLDHLAR
LAPDKSEQELRNYLGSFGFHGDKALDKVAPFSGGEKARLVLALVTWQKPNLLLLDEPTNHLDLEMRHALTMALQGFEGAM
VVVSHDRHLLRTTTDDFYLVHGGRVEAFDGDLDDYHKWLGEQEKEANAKPSDGIISANSALARKDQKRREAEFRQQTRPL
RQKLEKLEASMAKLQTRLAAVEEQLADPAIYEEAAKNKLSELLKSQGPIKEELDGVEQEWMSLSEELETMEQTFLA

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=521, Percent_Identity=38.7715930902111, Blast_Score=367, Evalue=1e-101,
Organism=Homo sapiens, GI10947137, Length=518, Percent_Identity=36.2934362934363, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI27881506, Length=518, Percent_Identity=36.2934362934363, Blast_Score=327, Evalue=3e-89,
Organism=Homo sapiens, GI10947135, Length=536, Percent_Identity=33.5820895522388, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI69354671, Length=536, Percent_Identity=33.5820895522388, Blast_Score=266, Evalue=3e-71,
Organism=Escherichia coli, GI1789751, Length=630, Percent_Identity=63.3333333333333, Blast_Score=839, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=524, Percent_Identity=34.5419847328244, Blast_Score=301, Evalue=1e-82,
Organism=Escherichia coli, GI1787182, Length=624, Percent_Identity=29.0064102564103, Blast_Score=258, Evalue=1e-69,
Organism=Escherichia coli, GI2367384, Length=529, Percent_Identity=31.3799621928166, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1788165, Length=197, Percent_Identity=32.48730964467, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787029, Length=222, Percent_Identity=26.5765765765766, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789672, Length=217, Percent_Identity=26.2672811059908, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788506, Length=228, Percent_Identity=26.7543859649123, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=37.1698113207547, Blast_Score=359, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI17555318, Length=523, Percent_Identity=36.3288718929254, Blast_Score=325, Evalue=5e-89,
Organism=Caenorhabditis elegans, GI17559834, Length=533, Percent_Identity=34.8968105065666, Blast_Score=308, Evalue=6e-84,
Organism=Caenorhabditis elegans, GI212646699, Length=340, Percent_Identity=25.8823529411765, Blast_Score=66, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=536, Percent_Identity=35.8208955223881, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6320874, Length=532, Percent_Identity=33.6466165413534, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6325030, Length=387, Percent_Identity=32.2997416020672, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324314, Length=412, Percent_Identity=28.6407766990291, Blast_Score=140, Evalue=8e-34,
Organism=Saccharomyces cerevisiae, GI6323278, Length=410, Percent_Identity=27.0731707317073, Blast_Score=134, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24666836, Length=540, Percent_Identity=37.4074074074074, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642252, Length=534, Percent_Identity=38.3895131086142, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI18859989, Length=534, Percent_Identity=38.3895131086142, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI24641342, Length=554, Percent_Identity=35.1985559566787, Blast_Score=316, Evalue=4e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 70670; Mature: 70670

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVASQIELIRGGRKLLDNASATIHPGHKVGLVGKNGSGKSTFFALVRGELAIDSGSFSL
CCCHHHHHHHHCCHHHHCCCCCEECCCCEEEEEECCCCCCCEEEEEEECCEEECCCCCCC
PAGWQIAGVAQETPALDCSALDYVIDGDKEFRSLEAQLAQAELDDNGILVAELHGKLDTI
CCCCEEECCCCCCCCCCCCHHHEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GAYSIRARAAELLHGLGFGDEQLGSPVRSFSGGWRMRLNLAQALLCRSDLLLLDEPTNHL
CHHHHHHHHHHHHHHCCCCHHHHCCHHHHCCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKGYQGTLVLISHDRDFLDSVISRIIHIENGKLNEYTGGYSDFELQRAE
CHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHH
QLAQQQSMYEKQQREVSHMQAYVDRFRYKASKARQAQSRLKAMERMEKLLPAHADSEFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
EFREPSALPTPLIAMENLCAGYGDKVILEKIKMNLVPGSRIGLLGRNGAGKSTFIKMLSG
EECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCC
TNPPLSGKLEVSAGVSIGYFAQHQLETLRLDDTPLDHLARLAPDKSEQELRNYLGSFGFH
CCCCCCCEEEEECCCEEHHHHHHHHHHEECCCCCHHHHHHHCCCCCHHHHHHHHHHCCCC
GDKALDKVAPFSGGEKARLVLALVTWQKPNLLLLDEPTNHLDLEMRHALTMALQGFEGAM
CCHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEE
VVVSHDRHLLRTTTDDFYLVHGGRVEAFDGDLDDYHKWLGEQEKEANAKPSDGIISANSA
EEEECCCEEEEECCCCEEEEECCEEEECCCCHHHHHHHCCCCHHHCCCCCCCCEEECCHH
LARKDQKRREAEFRQQTRPLRQKLEKLEASMAKLQTRLAAVEEQLADPAIYEEAAKNKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ELLKSQGPIKEELDGVEQEWMSLSEELETMEQTFLA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIVASQIELIRGGRKLLDNASATIHPGHKVGLVGKNGSGKSTFFALVRGELAIDSGSFSL
CCCHHHHHHHHCCHHHHCCCCCEECCCCEEEEEECCCCCCCEEEEEEECCEEECCCCCCC
PAGWQIAGVAQETPALDCSALDYVIDGDKEFRSLEAQLAQAELDDNGILVAELHGKLDTI
CCCCEEECCCCCCCCCCCCHHHEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCC
GAYSIRARAAELLHGLGFGDEQLGSPVRSFSGGWRMRLNLAQALLCRSDLLLLDEPTNHL
CHHHHHHHHHHHHHHCCCCHHHHCCHHHHCCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKGYQGTLVLISHDRDFLDSVISRIIHIENGKLNEYTGGYSDFELQRAE
CHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHEECCCCCCCCCCCCCCHHHHHHHH
QLAQQQSMYEKQQREVSHMQAYVDRFRYKASKARQAQSRLKAMERMEKLLPAHADSEFSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
EFREPSALPTPLIAMENLCAGYGDKVILEKIKMNLVPGSRIGLLGRNGAGKSTFIKMLSG
EECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCC
TNPPLSGKLEVSAGVSIGYFAQHQLETLRLDDTPLDHLARLAPDKSEQELRNYLGSFGFH
CCCCCCCEEEEECCCEEHHHHHHHHHHEECCCCCHHHHHHHCCCCCHHHHHHHHHHCCCC
GDKALDKVAPFSGGEKARLVLALVTWQKPNLLLLDEPTNHLDLEMRHALTMALQGFEGAM
CCHHHHHHCCCCCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCEE
VVVSHDRHLLRTTTDDFYLVHGGRVEAFDGDLDDYHKWLGEQEKEANAKPSDGIISANSA
EEEECCCEEEEECCCCEEEEECCEEEECCCCHHHHHHHCCCCHHHCCCCCCCCEEECCHH
LARKDQKRREAEFRQQTRPLRQKLEKLEASMAKLQTRLAAVEEQLADPAIYEEAAKNKLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ELLKSQGPIKEELDGVEQEWMSLSEELETMEQTFLA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]