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The map label for this gene is ushA [C]

Identifier: 145300180

GI number: 145300180

Start: 3560002

End: 3561840

Strand: Direct

Name: ushA [C]

Synonym: ASA_3291

Alternate gene names: 145300180

Gene position: 3560002-3561840 (Clockwise)

Preceding gene: 145300179

Following gene: 145300181

Centisome position: 75.71

GC content: 57.15

Gene sequence:

>1839_bases
ATGAAGAAGACGTTACTGGCCGTCACCGTCTCTATTACTCTGCTCGGGCTGACCGCCTGCAATTCAGAAAACAGCAGCAA
GGAGCATATTCCGCTGGATCTGACCATTGCCCATATCAATGATACCCACGCCCACCTCGACCCGACCGAAAATGCGCTGG
CCATCCAGCCCACCGGCCAGGAACTGTTCAAGTTCTACGCCAAACTGGGCGGCTATCCCCGTCTGAAGTTCAAGCTGGAC
GAGCTGCGCAGCCAGGCCGCCAACGAAGGCCGCAACTTCATGGTGCTCAACGGTGGTGATGCCTTCCAGGGCACCCTCTA
CTTCACCCAGTTCAAGGGGGAAGAGGAGTCTCGCCTGCTCTCCGACATGGGTATCGATGCCATGGTGCTGGGCAACCACG
AATTTGATTTGGGCAATCAGGCCATTAAAGATTTCGTCTCACGGGTGAATTTCCCTGTATTGGCTTCCAACATGGTGAAA
TCCAGTAGCGCCACCCTGAAAGACAGTGAAAATATTCATGAATATGTCATTAAAGAAATAAATGGCGAGAGCGTGGGTAT
TTTCGGGCTGGTGCTGGAAAATATGCATGATATCTCTTCACCGGATACCGATACCCAATTCCTGCCGATGATTGAAACCG
CCCAGAAAATGGTCGACACCCTCAAGTCAAAAGGCGCCAACAAGATCATCATGGTCACTCATATCGGTCTGCAAAATGAC
CAGGCCGTCGCCAAGGCGGTCAACGGTATCGACCTGATTGTAGGCGGTCACTCCCAGACCTTCCTCGGCGACATCAACGA
GATCAACACCATAGGCTACACGGCCCACAACCAGAATCCGGACGACGACAACACCTATGCCCAGCTGGTCGGCAATCCGG
ACGGTGGCAAGACCTGTATCGTGCAGGCCGGTGAATGGGCCAAAGGCTATGGCCTGGTCAACGTCTCCCTGAGCAAGGAA
GGCCAGATCACCAAGTGTGAGGGGCGCAATACCCTGATGACGGGCGACGATTTCACCAAGGACGTGGCCAAGAAGAAAGA
GCCCCTGAGTGGCAGCGAGCAGACCAATGTGGTCGACTTCATCACCAAGTCACCCGTCATCGAAATCGTGCCGGAGAACA
CCGCCATGCGCGATGTGATCGACACAGAGTACAAACCGGCCGTGGCCGAGCTCGAGGCCAAGATCATCGCCGACGTGCCG
ACCAAGTTGCCCCATGTGCGCGTGCCGGCCACCCCGGATGGCGCGGGTCTGATCGATCCCCTGGTGGCCGAATCCCTCTA
CTGGAAGCTCAACAAACTCAATACCAAGGTGGACTTCACCATCCAGAACGCCGGTGGTGTGCGCGCCGATGTGAACGCGG
GCCCGCTCTCCGTCGGTTACGTGATGGGCACCTTGCTGCCGTTTGGCAACAAGATCGCCGCCTTCAACCTCAAGGGCAAG
GACGTGCGCGCCACTCTGGAGTACGCCGTTGACTATTCCATCGGCCACGAGACCGGGATCAGCGCCTCCAGCGGTGCTTT
CCCTTACGTCGGCCACCTGAGCTACACCTATGATGGCAAACTGGCCAAGGGTTCCCGCATCACCAAGCTGGAGCTGCTGG
ACGCCAACGGCCAGTGGCAGCCGCTGGACGACGACAAGGTGTACCGTGTCGGTGCCAACACCTATATCGCCTCCGGCAAG
GATGGCTACAACGGCCTGCTCAAGCGCGAAGAGCTGCCCAACAAGGGTGACTACGTCGACTCTGGCGTCGGTGAGAACGA
GATGTTCATGGAGTATGCCGAGTCCCAGGGCACCCTCAATCCACTGCCCTATGCGACCGTGACCTACTTCAAGCCCTGA

Upstream 100 bases:

>100_bases
GCTCTCTTTATTTCCAATTACTGCTTTTTGCCTAGAATCGCCACACTCCTGTCATACAGGAACGATATACAGGACAATAA
CAACAAGAGGATTATTACCA

Downstream 100 bases:

>100_bases
TCAGGCTCACACGCTATTGCAACGGCGCCTGAGGGCGCCGTTTTTATGGCATACTCCCCGCCCATCGATGCCGAGGAGAA
TGTTTGATGGCCAAATACGA

Product: 5'-nucleotidase/2',3'-cyclic phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MKKTLLAVTVSITLLGLTACNSENSSKEHIPLDLTIAHINDTHAHLDPTENALAIQPTGQELFKFYAKLGGYPRLKFKLD
ELRSQAANEGRNFMVLNGGDAFQGTLYFTQFKGEEESRLLSDMGIDAMVLGNHEFDLGNQAIKDFVSRVNFPVLASNMVK
SSSATLKDSENIHEYVIKEINGESVGIFGLVLENMHDISSPDTDTQFLPMIETAQKMVDTLKSKGANKIIMVTHIGLQND
QAVAKAVNGIDLIVGGHSQTFLGDINEINTIGYTAHNQNPDDDNTYAQLVGNPDGGKTCIVQAGEWAKGYGLVNVSLSKE
GQITKCEGRNTLMTGDDFTKDVAKKKEPLSGSEQTNVVDFITKSPVIEIVPENTAMRDVIDTEYKPAVAELEAKIIADVP
TKLPHVRVPATPDGAGLIDPLVAESLYWKLNKLNTKVDFTIQNAGGVRADVNAGPLSVGYVMGTLLPFGNKIAAFNLKGK
DVRATLEYAVDYSIGHETGISASSGAFPYVGHLSYTYDGKLAKGSRITKLELLDANGQWQPLDDDKVYRVGANTYIASGK
DGYNGLLKREELPNKGDYVDSGVGENEMFMEYAESQGTLNPLPYATVTYFKP

Sequences:

>Translated_612_residues
MKKTLLAVTVSITLLGLTACNSENSSKEHIPLDLTIAHINDTHAHLDPTENALAIQPTGQELFKFYAKLGGYPRLKFKLD
ELRSQAANEGRNFMVLNGGDAFQGTLYFTQFKGEEESRLLSDMGIDAMVLGNHEFDLGNQAIKDFVSRVNFPVLASNMVK
SSSATLKDSENIHEYVIKEINGESVGIFGLVLENMHDISSPDTDTQFLPMIETAQKMVDTLKSKGANKIIMVTHIGLQND
QAVAKAVNGIDLIVGGHSQTFLGDINEINTIGYTAHNQNPDDDNTYAQLVGNPDGGKTCIVQAGEWAKGYGLVNVSLSKE
GQITKCEGRNTLMTGDDFTKDVAKKKEPLSGSEQTNVVDFITKSPVIEIVPENTAMRDVIDTEYKPAVAELEAKIIADVP
TKLPHVRVPATPDGAGLIDPLVAESLYWKLNKLNTKVDFTIQNAGGVRADVNAGPLSVGYVMGTLLPFGNKIAAFNLKGK
DVRATLEYAVDYSIGHETGISASSGAFPYVGHLSYTYDGKLAKGSRITKLELLDANGQWQPLDDDKVYRVGANTYIASGK
DGYNGLLKREELPNKGDYVDSGVGENEMFMEYAESQGTLNPLPYATVTYFKP
>Mature_612_residues
MKKTLLAVTVSITLLGLTACNSENSSKEHIPLDLTIAHINDTHAHLDPTENALAIQPTGQELFKFYAKLGGYPRLKFKLD
ELRSQAANEGRNFMVLNGGDAFQGTLYFTQFKGEEESRLLSDMGIDAMVLGNHEFDLGNQAIKDFVSRVNFPVLASNMVK
SSSATLKDSENIHEYVIKEINGESVGIFGLVLENMHDISSPDTDTQFLPMIETAQKMVDTLKSKGANKIIMVTHIGLQND
QAVAKAVNGIDLIVGGHSQTFLGDINEINTIGYTAHNQNPDDDNTYAQLVGNPDGGKTCIVQAGEWAKGYGLVNVSLSKE
GQITKCEGRNTLMTGDDFTKDVAKKKEPLSGSEQTNVVDFITKSPVIEIVPENTAMRDVIDTEYKPAVAELEAKIIADVP
TKLPHVRVPATPDGAGLIDPLVAESLYWKLNKLNTKVDFTIQNAGGVRADVNAGPLSVGYVMGTLLPFGNKIAAFNLKGK
DVRATLEYAVDYSIGHETGISASSGAFPYVGHLSYTYDGKLAKGSRITKLELLDANGQWQPLDDDKVYRVGANTYIASGK
DGYNGLLKREELPNKGDYVDSGVGENEMFMEYAESQGTLNPLPYATVTYFKP

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=551, Percent_Identity=27.5862068965517, Blast_Score=157, Evalue=4e-38,
Organism=Escherichia coli, GI1786687, Length=616, Percent_Identity=24.3506493506494, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24641187, Length=563, Percent_Identity=27.708703374778, Blast_Score=175, Evalue=8e-44,
Organism=Drosophila melanogaster, GI19922446, Length=576, Percent_Identity=24.3055555555556, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI24654424, Length=576, Percent_Identity=24.3055555555556, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI221329836, Length=586, Percent_Identity=25.5972696245734, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI19922444, Length=561, Percent_Identity=24.9554367201426, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28573524, Length=554, Percent_Identity=24.187725631769, Blast_Score=146, Evalue=5e-35,
Organism=Drosophila melanogaster, GI19921980, Length=182, Percent_Identity=31.3186813186813, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI161076508, Length=182, Percent_Identity=31.3186813186813, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24652512, Length=182, Percent_Identity=31.3186813186813, Blast_Score=90, Evalue=5e-18,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 66506; Mature: 66506

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLLAVTVSITLLGLTACNSENSSKEHIPLDLTIAHINDTHAHLDPTENALAIQPTGQ
CCCEEEEEEEEEEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCHH
ELFKFYAKLGGYPRLKFKLDELRSQAANEGRNFMVLNGGDAFQGTLYFTQFKGEEESRLL
HHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCHHHHHH
SDMGIDAMVLGNHEFDLGNQAIKDFVSRVNFPVLASNMVKSSSATLKDSENIHEYVIKEI
HHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHC
NGESVGIFGLVLENMHDISSPDTDTQFLPMIETAQKMVDTLKSKGANKIIMVTHIGLQND
CCCCEEEHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
QAVAKAVNGIDLIVGGHSQTFLGDINEINTIGYTAHNQNPDDDNTYAQLVGNPDGGKTCI
HHHHHHCCCEEEEECCCCCCEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCEEE
VQAGEWAKGYGLVNVSLSKEGQITKCEGRNTLMTGDDFTKDVAKKKEPLSGSEQTNVVDF
EECCCCCCCEEEEEEEECCCCCEEEECCCCEEECCCHHHHHHHHHCCCCCCCCCCCEEEE
ITKSPVIEIVPENTAMRDVIDTEYKPAVAELEAKIIADVPTKLPHVRVPATPDGAGLIDP
ECCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHEECCCCCCCEEECCCCCCCCCCHHH
LVAESLYWKLNKLNTKVDFTIQNAGGVRADVNAGPLSVGYVMGTLLPFGNKIAAFNLKGK
HHHHHHHHHHHHCCEEEEEEEECCCCEEEECCCCCEEHHHHHHHHHCCCCEEEEEECCCC
DVRATLEYAVDYSIGHETGISASSGAFPYVGHLSYTYDGKLAKGSRITKLELLDANGQWQ
CEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCCCCCC
PLDDDKVYRVGANTYIASGKDGYNGLLKREELPNKGDYVDSGVGENEMFMEYAESQGTLN
CCCCCCEEEEECCEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC
PLPYATVTYFKP
CCCCEEEEEECC
>Mature Secondary Structure
MKKTLLAVTVSITLLGLTACNSENSSKEHIPLDLTIAHINDTHAHLDPTENALAIQPTGQ
CCCEEEEEEEEEEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCHH
ELFKFYAKLGGYPRLKFKLDELRSQAANEGRNFMVLNGGDAFQGTLYFTQFKGEEESRLL
HHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCEEEEEECCCCCEEEEEEEEECCCHHHHHH
SDMGIDAMVLGNHEFDLGNQAIKDFVSRVNFPVLASNMVKSSSATLKDSENIHEYVIKEI
HHCCCCEEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHC
NGESVGIFGLVLENMHDISSPDTDTQFLPMIETAQKMVDTLKSKGANKIIMVTHIGLQND
CCCCEEEHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
QAVAKAVNGIDLIVGGHSQTFLGDINEINTIGYTAHNQNPDDDNTYAQLVGNPDGGKTCI
HHHHHHCCCEEEEECCCCCCEECCCCCCCEEEEEECCCCCCCCCCEEEEEECCCCCCEEE
VQAGEWAKGYGLVNVSLSKEGQITKCEGRNTLMTGDDFTKDVAKKKEPLSGSEQTNVVDF
EECCCCCCCEEEEEEEECCCCCEEEECCCCEEECCCHHHHHHHHHCCCCCCCCCCCEEEE
ITKSPVIEIVPENTAMRDVIDTEYKPAVAELEAKIIADVPTKLPHVRVPATPDGAGLIDP
ECCCCEEEEECCCCHHHHHHCCCCCCHHHHHHHHHEECCCCCCCEEECCCCCCCCCCHHH
LVAESLYWKLNKLNTKVDFTIQNAGGVRADVNAGPLSVGYVMGTLLPFGNKIAAFNLKGK
HHHHHHHHHHHHCCEEEEEEEECCCCEEEECCCCCEEHHHHHHHHHCCCCEEEEEECCCC
DVRATLEYAVDYSIGHETGISASSGAFPYVGHLSYTYDGKLAKGSRITKLELLDANGQWQ
CEEEEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCEEEEEEECCCCCCC
PLDDDKVYRVGANTYIASGKDGYNGLLKREELPNKGDYVDSGVGENEMFMEYAESQGTLN
CCCCCCEEEEECCEEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC
PLPYATVTYFKP
CCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]