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The map label for this gene is cheA [H]

Identifier: 145300162

GI number: 145300162

Start: 3530090

End: 3532303

Strand: Direct

Name: cheA [H]

Synonym: ASA_3266

Alternate gene names: 145300162

Gene position: 3530090-3532303 (Clockwise)

Preceding gene: 145300161

Following gene: 145300163

Centisome position: 75.07

GC content: 59.21

Gene sequence:

>2214_bases
GTGAGCATCAATCTTGATCAGGCCCTGCAAACCTATATAGCCGAGGCACGCGAACTGCTGGAAGAGATGGAGTCTTCCCT
GCTGACCCTGGAAAACGACCCGGAGAACAGCGAGCTGATCGGTGCCATCTTTCGGGCGGCACATACCATCAAGGGCTCCG
CTGGTCTGTTCGGCTTGCAGCCCATCGTCAGCTTTACCCACATAGTCGAGGATCTGCTCGATCAGGTGCGCAATCAGCAA
CTGGGGATCACGACTGCGCTCATCAAGGATCTGCTGGAGAGCCGGGATCATATCGAGCGGCTGGTCTATCTGGTTGCAGA
GCTAGGGTCGGCGCCAGGGGACGATGAACTGGCGCAAGACGCTCAGCTGAGGCTCAACTTGGCCAGACATCAAACTGCCA
GCCAGAGCCAGCTGCCGGAGCGCACTGCGTCAACCATCCCAGACCCGGTCAGCAAGGAGGAGGGGCACACCAGCGCCACT
TCCCTGTGGCACATCTCCCTGCGCTTTGGCCCGGATGTGCTGCGTAACGGTATGGATCCCACCTCGTTTTTACGTTATCT
CGGCACCATCGGCACCCTCTGCGCCATCGAAACCCTCCACGATACCCTGCCCGACTGGGAACATTTTGATCCGGAAACCT
GCTACCTCGGCTATGAACTCGATGTCGATACCCAGGCCGACAAGAGCACCCTGAGCGATGTGTTTGAATTCGTACGTGAC
GACTGCCGCATCACCATACTGCCCCCGCATAGCAAGATTGCTGAATACATAGACCTCATCAATGAATTGCCGGAAGACAA
CGACATGCTGGGGCAACTGCTGGTCAAGACAGGAGCGTTGACGGCTAGCGAACTGGCACTGGGCCTGCAAACTCAGCATG
ACGACCAGCGAACAGAGAACAGCAAGCTGGGAGAAATACTGGTCGCTCAGGGCGCAGTCGACGGAGTCGTGGTGGATGCG
GCGCTCAAGAAACAGAACCAGAACAAGGAGAACAAAAACAAGGAGGGACGCTATGTTCGGGTGCACGCCGACAAACTGGA
TGAGCTGATCAATCTGGTCGGCGAGCTGGTGGTCGCCAGCTCGGGTGCCAGCCTGCTGGCACAGCGCTCGCGGGACAGCC
AGCTGCAGGAGGCCAACTCCACCATTGCCATGCTGGTTGAAGAGATCCGGGACGGGGCCTTGCACCTGCGCATGGTGCCC
ATCGGCGACACCTTCAACCGCTTCCAGCGGGTCGTACGGGATGTCAGCCACGAGCTGAACAAGGACATTGCGCTGGTCAT
CACGGGCGGAGATACCGAGCTCGACAAGTCTGTGGTGGAGAAGATTGGCGATCCCCTGATGCATCTGGTTCGCAACTCCA
TGGATCACGGCATAGAGTCGGCCGAGCAGCGCCTCGCGGCAGGCAAACCGGCAAGAGGCACCTTGACTCTCAACGCCTAT
CACGACTCCGGCAGCATCGTCATCGAGATCCTGGACGACGGTGCCGGACTCAACAAGGCAAGGATCCTGCAAAAGGCGCA
GGAGCGGGGGCTGGTGGCCGCCGGCGCAACATTGACGGATCAGGAGATCTATCAGCTCATCTTCGAGGCAGGCTTCTCTA
CCGCCGAGGCCGTTACCAACCTCTCGGGCCGGGGCGTCGGTATGGACGTGGTCAAACGCAACATCACGGCCCTGCGCGGC
AGCGTCGAGCTGGACAGCAAGCCGGGACAAGGCACCCGGGTTCAAATCAGGCTGCCACTGACTTTGGCCATCATCGACGG
TTTTCTGGTTCGAGTCAGCACCACCCATTACGTCATCCCGCTCGACATGGTGATCGAATGCGTGGAGCTGACCCAGAGTG
CACTGGATGACACCCAGGGACGCAACTACATCAATCTGCGTGGCGAGGTACTGCCATTTGTCAGGCTTCAGCACTACTTC
GACGTCGAGGGGGCCAGAGGACGCAGGGAAAACATCGTCGTCGTCAGTCACGGCGGCAAGAAATCCGGGCTGGTGGTCGA
CGAGCTGCTGGGGGAGTTCCAGACCGTCATCAAGCCGCTCGGCAAGCTGTTTCAGCGCCTGCAGGGGATCAGTGGCTCCA
CCATTTTGGGGGGTGGCGAGGTCGCCCTGATCCTGGACATCCCCTCCCTCATTCAACATGCCATCGATCAAGAGCTAGGC
CAGCTGAGCCAGTACGCCATTCCTCGCATGCAAACCCAACCAAGAGCCAATTAA

Upstream 100 bases:

>100_bases
ATGCGCTGGAGCTGTGCCAGCTGGCTGCTTTCTTTGGCGATCCCACCCTTATTCCCCACGCAGATCACGCCTAGGCAGTC
CCAGTGACAAGGAGGCATTC

Downstream 100 bases:

>100_bases
CGCCAGGAGCCAGTCATGTTCAAAAACTCCACCATTAAAATGCGCCTCACCATCTTGCTCTGCCTGTTATGCGTGCTGCT
GGCGGTGGGCGGGCTGGGAC

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 736

Protein sequence:

>737_residues
MSINLDQALQTYIAEARELLEEMESSLLTLENDPENSELIGAIFRAAHTIKGSAGLFGLQPIVSFTHIVEDLLDQVRNQQ
LGITTALIKDLLESRDHIERLVYLVAELGSAPGDDELAQDAQLRLNLARHQTASQSQLPERTASTIPDPVSKEEGHTSAT
SLWHISLRFGPDVLRNGMDPTSFLRYLGTIGTLCAIETLHDTLPDWEHFDPETCYLGYELDVDTQADKSTLSDVFEFVRD
DCRITILPPHSKIAEYIDLINELPEDNDMLGQLLVKTGALTASELALGLQTQHDDQRTENSKLGEILVAQGAVDGVVVDA
ALKKQNQNKENKNKEGRYVRVHADKLDELINLVGELVVASSGASLLAQRSRDSQLQEANSTIAMLVEEIRDGALHLRMVP
IGDTFNRFQRVVRDVSHELNKDIALVITGGDTELDKSVVEKIGDPLMHLVRNSMDHGIESAEQRLAAGKPARGTLTLNAY
HDSGSIVIEILDDGAGLNKARILQKAQERGLVAAGATLTDQEIYQLIFEAGFSTAEAVTNLSGRGVGMDVVKRNITALRG
SVELDSKPGQGTRVQIRLPLTLAIIDGFLVRVSTTHYVIPLDMVIECVELTQSALDDTQGRNYINLRGEVLPFVRLQHYF
DVEGARGRRENIVVVSHGGKKSGLVVDELLGEFQTVIKPLGKLFQRLQGISGSTILGGGEVALILDIPSLIQHAIDQELG
QLSQYAIPRMQTQPRAN

Sequences:

>Translated_737_residues
MSINLDQALQTYIAEARELLEEMESSLLTLENDPENSELIGAIFRAAHTIKGSAGLFGLQPIVSFTHIVEDLLDQVRNQQ
LGITTALIKDLLESRDHIERLVYLVAELGSAPGDDELAQDAQLRLNLARHQTASQSQLPERTASTIPDPVSKEEGHTSAT
SLWHISLRFGPDVLRNGMDPTSFLRYLGTIGTLCAIETLHDTLPDWEHFDPETCYLGYELDVDTQADKSTLSDVFEFVRD
DCRITILPPHSKIAEYIDLINELPEDNDMLGQLLVKTGALTASELALGLQTQHDDQRTENSKLGEILVAQGAVDGVVVDA
ALKKQNQNKENKNKEGRYVRVHADKLDELINLVGELVVASSGASLLAQRSRDSQLQEANSTIAMLVEEIRDGALHLRMVP
IGDTFNRFQRVVRDVSHELNKDIALVITGGDTELDKSVVEKIGDPLMHLVRNSMDHGIESAEQRLAAGKPARGTLTLNAY
HDSGSIVIEILDDGAGLNKARILQKAQERGLVAAGATLTDQEIYQLIFEAGFSTAEAVTNLSGRGVGMDVVKRNITALRG
SVELDSKPGQGTRVQIRLPLTLAIIDGFLVRVSTTHYVIPLDMVIECVELTQSALDDTQGRNYINLRGEVLPFVRLQHYF
DVEGARGRRENIVVVSHGGKKSGLVVDELLGEFQTVIKPLGKLFQRLQGISGSTILGGGEVALILDIPSLIQHAIDQELG
QLSQYAIPRMQTQPRAN
>Mature_736_residues
SINLDQALQTYIAEARELLEEMESSLLTLENDPENSELIGAIFRAAHTIKGSAGLFGLQPIVSFTHIVEDLLDQVRNQQL
GITTALIKDLLESRDHIERLVYLVAELGSAPGDDELAQDAQLRLNLARHQTASQSQLPERTASTIPDPVSKEEGHTSATS
LWHISLRFGPDVLRNGMDPTSFLRYLGTIGTLCAIETLHDTLPDWEHFDPETCYLGYELDVDTQADKSTLSDVFEFVRDD
CRITILPPHSKIAEYIDLINELPEDNDMLGQLLVKTGALTASELALGLQTQHDDQRTENSKLGEILVAQGAVDGVVVDAA
LKKQNQNKENKNKEGRYVRVHADKLDELINLVGELVVASSGASLLAQRSRDSQLQEANSTIAMLVEEIRDGALHLRMVPI
GDTFNRFQRVVRDVSHELNKDIALVITGGDTELDKSVVEKIGDPLMHLVRNSMDHGIESAEQRLAAGKPARGTLTLNAYH
DSGSIVIEILDDGAGLNKARILQKAQERGLVAAGATLTDQEIYQLIFEAGFSTAEAVTNLSGRGVGMDVVKRNITALRGS
VELDSKPGQGTRVQIRLPLTLAIIDGFLVRVSTTHYVIPLDMVIECVELTQSALDDTQGRNYINLRGEVLPFVRLQHYFD
VEGARGRRENIVVVSHGGKKSGLVVDELLGEFQTVIKPLGKLFQRLQGISGSTILGGGEVALILDIPSLIQHAIDQELGQ
LSQYAIPRMQTQPRAN

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=403, Percent_Identity=46.1538461538462, Blast_Score=333, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80830; Mature: 80699

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINLDQALQTYIAEARELLEEMESSLLTLENDPENSELIGAIFRAAHTIKGSAGLFGLQ
CCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
PIVSFTHIVEDLLDQVRNQQLGITTALIKDLLESRDHIERLVYLVAELGSAPGDDELAQD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AQLRLNLARHQTASQSQLPERTASTIPDPVSKEEGHTSATSLWHISLRFGPDVLRNGMDP
HHHHHHHHHHCCCCHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECHHHHHCCCCH
TSFLRYLGTIGTLCAIETLHDTLPDWEHFDPETCYLGYELDVDTQADKSTLSDVFEFVRD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHC
DCRITILPPHSKIAEYIDLINELPEDNDMLGQLLVKTGALTASELALGLQTQHDDQRTEN
CCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHCCC
SKLGEILVAQGAVDGVVVDAALKKQNQNKENKNKEGRYVRVHADKLDELINLVGELVVAS
CHHHHEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHC
SGASLLAQRSRDSQLQEANSTIAMLVEEIRDGALHLRMVPIGDTFNRFQRVVRDVSHELN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCC
KDIALVITGGDTELDKSVVEKIGDPLMHLVRNSMDHGIESAEQRLAAGKPARGTLTLNAY
CCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEE
HDSGSIVIEILDDGAGLNKARILQKAQERGLVAAGATLTDQEIYQLIFEAGFSTAEAVTN
ECCCCEEEEEECCCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHC
LSGRGVGMDVVKRNITALRGSVELDSKPGQGTRVQIRLPLTLAIIDGFLVRVSTTHYVIP
CCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCEEEEEECHHHHHHHHHHEEEECCEEEEE
LDMVIECVELTQSALDDTQGRNYINLRGEVLPFVRLQHYFDVEGARGRRENIVVVSHGGK
HHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
KSGLVVDELLGEFQTVIKPLGKLFQRLQGISGSTILGGGEVALILDIPSLIQHAIDQELG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHH
QLSQYAIPRMQTQPRAN
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SINLDQALQTYIAEARELLEEMESSLLTLENDPENSELIGAIFRAAHTIKGSAGLFGLQ
CCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHH
PIVSFTHIVEDLLDQVRNQQLGITTALIKDLLESRDHIERLVYLVAELGSAPGDDELAQD
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
AQLRLNLARHQTASQSQLPERTASTIPDPVSKEEGHTSATSLWHISLRFGPDVLRNGMDP
HHHHHHHHHHCCCCHHHCCHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECHHHHHCCCCH
TSFLRYLGTIGTLCAIETLHDTLPDWEHFDPETCYLGYELDVDTQADKSTLSDVFEFVRD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHC
DCRITILPPHSKIAEYIDLINELPEDNDMLGQLLVKTGALTASELALGLQTQHDDQRTEN
CCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHCCC
SKLGEILVAQGAVDGVVVDAALKKQNQNKENKNKEGRYVRVHADKLDELINLVGELVVAS
CHHHHEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHC
SGASLLAQRSRDSQLQEANSTIAMLVEEIRDGALHLRMVPIGDTFNRFQRVVRDVSHELN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCC
KDIALVITGGDTELDKSVVEKIGDPLMHLVRNSMDHGIESAEQRLAAGKPARGTLTLNAY
CCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEEE
HDSGSIVIEILDDGAGLNKARILQKAQERGLVAAGATLTDQEIYQLIFEAGFSTAEAVTN
ECCCCEEEEEECCCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHC
LSGRGVGMDVVKRNITALRGSVELDSKPGQGTRVQIRLPLTLAIIDGFLVRVSTTHYVIP
CCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCEEEEEECHHHHHHHHHHEEEECCEEEEE
LDMVIECVELTQSALDDTQGRNYINLRGEVLPFVRLQHYFDVEGARGRRENIVVVSHGGK
HHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
KSGLVVDELLGEFQTVIKPLGKLFQRLQGISGSTILGGGEVALILDIPSLIQHAIDQELG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHH
QLSQYAIPRMQTQPRAN
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]