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The map label for this gene is cheW [H]

Identifier: 145300163

GI number: 145300163

Start: 3534238

End: 3534804

Strand: Direct

Name: cheW [H]

Synonym: ASA_3268

Alternate gene names: 145300163

Gene position: 3534238-3534804 (Clockwise)

Preceding gene: 145300162

Following gene: 145300164

Centisome position: 75.16

GC content: 55.73

Gene sequence:

>567_bases
ATGTCAACCGAAGTGGCCGCGCCCCCCAGCACACTGGCCCATGACAATCAGGGCGACGCCCAATACCTGACATTCCTGAT
CAATGGCGAGATGTTTGCCATCAATATTCTCGGGGTCAAAGAGATCATCGAGTACGGCAACATCACTCCTATCCCCATGA
TGCCAAGCTTCATCCGGGGCGTGATCAATCTCAGGGGAGCTGTGGTATCAGTGGTGGATCTCAATGCCCGCTTTGGCAAT
GCCCCTTCCAGCATCACTCGCCGCAGCTGCATCGTCATCATCGAAGGAATACACCCGGATGACTCGGAGCATGGCAATCA
GGACATCGGCGTCGTAGTGGATTCGGTATCTGAGGTGCTGACCATTCCCTGCGACGAGATAGAGCCGCCCCCCAGCTTCG
GGGCTCACATCCGGGCCGACTTCATTACCGGCATGGGCAAGGTGAATGGCAAGTTCGTCATTCTCATCAATACCGAGAAG
GTGCTCTCCATCGACGAAATGGCACAACTCAGCGAACTGACCCAGCAGCAGGAACGACAGCTGGAGCACAGAGTGCAAAC
CCCTTAA

Upstream 100 bases:

>100_bases
TGTCATGCCTGCCCAACACCCGCTGCACGGCAACACGGCGCCGCAACCCCTGGTTGACGAAGCCGACTTTGTCCGCTTTT
AACCGGAGAGACCCATGAGC

Downstream 100 bases:

>100_bases
GCAGGGTATTAAAAACAGCAAGGGTGACGCTCACACCACACAGCAATGGCATGTCGCACAAGGATAAGGCTCATGACTCA
ATCATTCTTTGGCAATCTCT

Product: chemotaxis protein CheW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSTEVAAPPSTLAHDNQGDAQYLTFLINGEMFAINILGVKEIIEYGNITPIPMMPSFIRGVINLRGAVVSVVDLNARFGN
APSSITRRSCIVIIEGIHPDDSEHGNQDIGVVVDSVSEVLTIPCDEIEPPPSFGAHIRADFITGMGKVNGKFVILINTEK
VLSIDEMAQLSELTQQQERQLEHRVQTP

Sequences:

>Translated_188_residues
MSTEVAAPPSTLAHDNQGDAQYLTFLINGEMFAINILGVKEIIEYGNITPIPMMPSFIRGVINLRGAVVSVVDLNARFGN
APSSITRRSCIVIIEGIHPDDSEHGNQDIGVVVDSVSEVLTIPCDEIEPPPSFGAHIRADFITGMGKVNGKFVILINTEK
VLSIDEMAQLSELTQQQERQLEHRVQTP
>Mature_187_residues
STEVAAPPSTLAHDNQGDAQYLTFLINGEMFAINILGVKEIIEYGNITPIPMMPSFIRGVINLRGAVVSVVDLNARFGNA
PSSITRRSCIVIIEGIHPDDSEHGNQDIGVVVDSVSEVLTIPCDEIEPPPSFGAHIRADFITGMGKVNGKFVILINTEKV
LSIDEMAQLSELTQQQERQLEHRVQTP

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=168, Percent_Identity=33.3333333333333, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 20491; Mature: 20359

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEVAAPPSTLAHDNQGDAQYLTFLINGEMFAINILGVKEIIEYGNITPIPMMPSFIRG
CCCCCCCCCCHHCCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHCCCCCCCCCHHHHHH
VINLRGAVVSVVDLNARFGNAPSSITRRSCIVIIEGIHPDDSEHGNQDIGVVVDSVSEVL
HHHHCCCEEEEEEECCCCCCCCCHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHE
TIPCDEIEPPPSFGAHIRADFITGMGKVNGKFVILINTEKVLSIDEMAQLSELTQQQERQ
ECCCCCCCCCCCCCCEEEHHHHHCCCCCCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHH
LEHRVQTP
HHHHCCCC
>Mature Secondary Structure 
STEVAAPPSTLAHDNQGDAQYLTFLINGEMFAINILGVKEIIEYGNITPIPMMPSFIRG
CCCCCCCCCHHCCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHCCCCCCCCCHHHHHH
VINLRGAVVSVVDLNARFGNAPSSITRRSCIVIIEGIHPDDSEHGNQDIGVVVDSVSEVL
HHHHCCCEEEEEEECCCCCCCCCHHCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHE
TIPCDEIEPPPSFGAHIRADFITGMGKVNGKFVILINTEKVLSIDEMAQLSELTQQQERQ
ECCCCCCCCCCCCCCEEEHHHHHCCCCCCCEEEEEECCCHHCCHHHHHHHHHHHHHHHHH
LEHRVQTP
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]