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The map label for this gene is fabH2 [H]

Identifier: 145300158

GI number: 145300158

Start: 3526775

End: 3527863

Strand: Direct

Name: fabH2 [H]

Synonym: ASA_3262

Alternate gene names: 145300158

Gene position: 3526775-3527863 (Clockwise)

Preceding gene: 145300152

Following gene: 145300159

Centisome position: 75.0

GC content: 61.34

Gene sequence:

>1089_bases
ATGAAATACGCCAATATCACCGGTTGGGGCAAATGTCTGCCTCCCTCTGTGCTGACCAACGATGACCTCAGCACCATCAT
GGATACGTCGGATGAGTGGATCTATCCGCGTACCGGTATCAAGGCCCGCCGGATCTCCCATGTCAGCACCTCGGATCTCG
CCACCCTGGCCGGTCGTCGCGCCCTCGCCTGTGCCGGTCTCGACGCCAGCGATCTCGATGGCATCATACTGGCCACAGCC
ACCCCGGATAATCTGCTGCCGAGCGCGGCCTCTGCGGTGCAGAAGAAGCTCGGCGCCGTCAACGCCGCCGTGTTCGACCT
CAACGCCGCCTGTACCGGTTTCGTCTACTCCCTCTCCGTCGCCACCTCGCTGGTGCAAACCGGCATGATGAAGAAGGTGC
TGGTGATCGGCGCCGAGCGCCTGACCTATCTGCTGGACTGGGCACGCCGGGACACTGCCGTGCTGTTTGGTGATGGCGCA
GGTGCCGTAGTGATCGAAGCAAGCGAGCAGGAGTGCGGCCTTATCGCCAACAAGCTCGGCTGTGACAGTGAAGCACGGGA
GATACTGCACGTCCCGAACTTTGGTACCGATCGAGTGCGTTTTGCCGATGTCGATGGCCTCTTCACCTTCAACTTCGAAG
GGCCAGAGATCTTCAAACGCGCCGTGCGCGGCATGGGAGAAGCCACCAGCTCAGTGCTGGCTCAAGCTGGCATAGATCCT
GAACAGGTCGATCTCATAGTGCCGCACCAGGCCAACATTCGCATTATCGAGACTCTGGCCAAGCGCATGAACGCCCCCAT
GGAAAAGGTGATGGTCAACATCGAAAACTACGGTAATACCTCCGCCGCTACCGTGCCTATCGCCCTGTGCGAAGCGCTGG
AGCAAGGCCGCGTCAAGCCGAACTCCTATCTGCTCACCGCCGCCTTCGGTGCCGGTCTGACCTGGGGCGCCGCCATCATC
AAATGGGGCGATCGCGTTACTCCTGTCGGCCAATGCGATGCCGAACTGCCCCCGTGCGACCAGAGTGCGCTGGAGCTGAT
TGCCCACGCCGTCGAAGGCTGCCAGAAGGCCCACGCCAACCAGGCCTGA

Upstream 100 bases:

>100_bases
TTCAGATAACGATGACCACAAGATGACAGTGGTTGTCTCGTGCGGCATAATTGCGCGATTTTCCGCCCGCGGGCGATCCA
CTTTGAGAAGCGGTAACAAG

Downstream 100 bases:

>100_bases
TCCTCATCGGGAGCCTGATCATCAGGCTCCTCTCTTCTCCCTTTACCGCCTTCCCGCTCGTTAGATCATCACCACGCTAC
CGCATCCATATTCCAGTTTT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 2; Beta-ketoacyl-ACP synthase III 2; KAS III 2 [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKYANITGWGKCLPPSVLTNDDLSTIMDTSDEWIYPRTGIKARRISHVSTSDLATLAGRRALACAGLDASDLDGIILATA
TPDNLLPSAASAVQKKLGAVNAAVFDLNAACTGFVYSLSVATSLVQTGMMKKVLVIGAERLTYLLDWARRDTAVLFGDGA
GAVVIEASEQECGLIANKLGCDSEAREILHVPNFGTDRVRFADVDGLFTFNFEGPEIFKRAVRGMGEATSSVLAQAGIDP
EQVDLIVPHQANIRIIETLAKRMNAPMEKVMVNIENYGNTSAATVPIALCEALEQGRVKPNSYLLTAAFGAGLTWGAAII
KWGDRVTPVGQCDAELPPCDQSALELIAHAVEGCQKAHANQA

Sequences:

>Translated_362_residues
MKYANITGWGKCLPPSVLTNDDLSTIMDTSDEWIYPRTGIKARRISHVSTSDLATLAGRRALACAGLDASDLDGIILATA
TPDNLLPSAASAVQKKLGAVNAAVFDLNAACTGFVYSLSVATSLVQTGMMKKVLVIGAERLTYLLDWARRDTAVLFGDGA
GAVVIEASEQECGLIANKLGCDSEAREILHVPNFGTDRVRFADVDGLFTFNFEGPEIFKRAVRGMGEATSSVLAQAGIDP
EQVDLIVPHQANIRIIETLAKRMNAPMEKVMVNIENYGNTSAATVPIALCEALEQGRVKPNSYLLTAAFGAGLTWGAAII
KWGDRVTPVGQCDAELPPCDQSALELIAHAVEGCQKAHANQA
>Mature_362_residues
MKYANITGWGKCLPPSVLTNDDLSTIMDTSDEWIYPRTGIKARRISHVSTSDLATLAGRRALACAGLDASDLDGIILATA
TPDNLLPSAASAVQKKLGAVNAAVFDLNAACTGFVYSLSVATSLVQTGMMKKVLVIGAERLTYLLDWARRDTAVLFGDGA
GAVVIEASEQECGLIANKLGCDSEAREILHVPNFGTDRVRFADVDGLFTFNFEGPEIFKRAVRGMGEATSSVLAQAGIDP
EQVDLIVPHQANIRIIETLAKRMNAPMEKVMVNIENYGNTSAATVPIALCEALEQGRVKPNSYLLTAAFGAGLTWGAAII
KWGDRVTPVGQCDAELPPCDQSALELIAHAVEGCQKAHANQA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=41.9254658385093, Blast_Score=243, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 38462; Mature: 38462

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYANITGWGKCLPPSVLTNDDLSTIMDTSDEWIYPRTGIKARRISHVSTSDLATLAGRR
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEECCCCCCCHHHHCCCCHHHHHHHHCCC
ALACAGLDASDLDGIILATATPDNLLPSAASAVQKKLGAVNAAVFDLNAACTGFVYSLSV
EEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHH
ATSLVQTGMMKKVLVIGAERLTYLLDWARRDTAVLFGDGAGAVVIEASEQECGLIANKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCHHHHHCC
CDSEAREILHVPNFGTDRVRFADVDGLFTFNFEGPEIFKRAVRGMGEATSSVLAQAGIDP
CCHHHHHEEECCCCCCCCEEEEECCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHCCCCH
EQVDLIVPHQANIRIIETLAKRMNAPMEKVMVNIENYGNTSAATVPIALCEALEQGRVKP
HHEEEECCCCCCHHHHHHHHHHHCCCHHHHEEEHHCCCCCCHHHHHHHHHHHHHHCCCCC
NSYLLTAAFGAGLTWGAAIIKWGDRVTPVGQCDAELPPCDQSALELIAHAVEGCQKAHAN
CCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
QA
CC
>Mature Secondary Structure
MKYANITGWGKCLPPSVLTNDDLSTIMDTSDEWIYPRTGIKARRISHVSTSDLATLAGRR
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCEECCCCCCCHHHHCCCCHHHHHHHHCCC
ALACAGLDASDLDGIILATATPDNLLPSAASAVQKKLGAVNAAVFDLNAACTGFVYSLSV
EEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHH
ATSLVQTGMMKKVLVIGAERLTYLLDWARRDTAVLFGDGAGAVVIEASEQECGLIANKLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCHHHHHCC
CDSEAREILHVPNFGTDRVRFADVDGLFTFNFEGPEIFKRAVRGMGEATSSVLAQAGIDP
CCHHHHHEEECCCCCCCCEEEEECCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHCCCCH
EQVDLIVPHQANIRIIETLAKRMNAPMEKVMVNIENYGNTSAATVPIALCEALEQGRVKP
HHEEEECCCCCCHHHHHHHHHHHCCCHHHHEEEHHCCCCCCHHHHHHHHHHHHHHCCCCC
NSYLLTAAFGAGLTWGAAIIKWGDRVTPVGQCDAELPPCDQSALELIAHAVEGCQKAHAN
CCEEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]