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The map label for this gene is nhaA1 [H]

Identifier: 145300114

GI number: 145300114

Start: 3484328

End: 3485077

Strand: Direct

Name: nhaA1 [H]

Synonym: ASA_3216

Alternate gene names: 145300114

Gene position: 3484328-3485077 (Clockwise)

Preceding gene: 145300112

Following gene: 145300136

Centisome position: 74.1

GC content: 59.6

Gene sequence:

>750_bases
ATGAGAATCAAACATGCCCTGCTTTGCGCCCTGACTGGCGCCACCCTGCTTGCGGCGCCGGTTCAGGCAAGCGAGCTGAC
CAAGAGCGATGTCGAGCAAATCGTGCGCGACTATCTGGTCAAGAATCCGGAGATCCTGGTCGAGATGTCCAATGCCCTGC
GTGCCAAGCAGGAGAGCCAGCAGGCGGCCAACGACAAAAGCCTGATCGAGGCGCACGCCAAGCAGCTCTATTCCAATAAG
GATCCCGAGAGCGGCAACCCCAAGGGCAGCCTGACCGTGGTCGAGTTCTTCGATTACAACTGCGGTTACTGCAAGCGCGC
CCATCCGCTGATCAAGCAACTGCTGGGTGAAGACAAGGATATCCGCTACATCTACAAGCAGTTCCCCATCCTGAGCGAGA
GCTCCTACTTCGCCGCCCGGGCGGCGCTGGCGGTGCAACTGGGTCAACCTGACAAGTACCAGGCCTTCCACGAGAAGCTG
TATGCCCATCAGGGCCCGCTGTCCGATGAAGCCCAGGTGAAGCAGTTAGCGGAAGCGGCCGGGGTGAACTGGAGCAAGGT
CGAGGCCAAGATCAAGGACGGCAGCATAGATCAGAACCTCGGCACCAACCGGGCGCTGGCCGAAGCCATGAGTATCTCAG
GCACACCGGCCTTCATCATAGGTGACCAGATACTGCGTGGCGCACCCCGCGATCTGGCGAGCCTGAAAGGCTTCATCAAG
GATGTGCGAGCGGGCAAGAGCATTCAGTAA

Upstream 100 bases:

>100_bases
AAAACGGGCAGAAACAGCGCTTTTTCAACCAGATAACTTGACTTGAAAACAGACTCACCCACTATAGTGACCATCACGAA
ATTCCCAGCAAGATGGACTT

Downstream 100 bases:

>100_bases
CTAGGCCCTTCGCACATAAAAAAACGCCCCGGCATTGCGATGCCGGGGCGTTTTGCCATTCAGGCTTTAGCCCTCAGAAC
TCCTGGGCCGTCGCGAGGAG

Product: DsbA family, Com1-like subfamily protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 1 [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MRIKHALLCALTGATLLAAPVQASELTKSDVEQIVRDYLVKNPEILVEMSNALRAKQESQQAANDKSLIEAHAKQLYSNK
DPESGNPKGSLTVVEFFDYNCGYCKRAHPLIKQLLGEDKDIRYIYKQFPILSESSYFAARAALAVQLGQPDKYQAFHEKL
YAHQGPLSDEAQVKQLAEAAGVNWSKVEAKIKDGSIDQNLGTNRALAEAMSISGTPAFIIGDQILRGAPRDLASLKGFIK
DVRAGKSIQ

Sequences:

>Translated_249_residues
MRIKHALLCALTGATLLAAPVQASELTKSDVEQIVRDYLVKNPEILVEMSNALRAKQESQQAANDKSLIEAHAKQLYSNK
DPESGNPKGSLTVVEFFDYNCGYCKRAHPLIKQLLGEDKDIRYIYKQFPILSESSYFAARAALAVQLGQPDKYQAFHEKL
YAHQGPLSDEAQVKQLAEAAGVNWSKVEAKIKDGSIDQNLGTNRALAEAMSISGTPAFIIGDQILRGAPRDLASLKGFIK
DVRAGKSIQ
>Mature_249_residues
MRIKHALLCALTGATLLAAPVQASELTKSDVEQIVRDYLVKNPEILVEMSNALRAKQESQQAANDKSLIEAHAKQLYSNK
DPESGNPKGSLTVVEFFDYNCGYCKRAHPLIKQLLGEDKDIRYIYKQFPILSESSYFAARAALAVQLGQPDKYQAFHEKL
YAHQGPLSDEAQVKQLAEAAGVNWSKVEAKIKDGSIDQNLGTNRALAEAMSISGTPAFIIGDQILRGAPRDLASLKGFIK
DVRAGKSIQ

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 27316; Mature: 27316

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIKHALLCALTGATLLAAPVQASELTKSDVEQIVRDYLVKNPEILVEMSNALRAKQESQ
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHH
QAANDKSLIEAHAKQLYSNKDPESGNPKGSLTVVEFFDYNCGYCKRAHPLIKQLLGEDKD
HHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCH
IRYIYKQFPILSESSYFAARAALAVQLGQPDKYQAFHEKLYAHQGPLSDEAQVKQLAEAA
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GVNWSKVEAKIKDGSIDQNLGTNRALAEAMSISGTPAFIIGDQILRGAPRDLASLKGFIK
CCCHHHHEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEECHHHHCCCCHHHHHHHHHHH
DVRAGKSIQ
HHHCCCCCC
>Mature Secondary Structure
MRIKHALLCALTGATLLAAPVQASELTKSDVEQIVRDYLVKNPEILVEMSNALRAKQESQ
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHEEEHHHHHHHHHHHH
QAANDKSLIEAHAKQLYSNKDPESGNPKGSLTVVEFFDYNCGYCKRAHPLIKQLLGEDKD
HHCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCH
IRYIYKQFPILSESSYFAARAALAVQLGQPDKYQAFHEKLYAHQGPLSDEAQVKQLAEAA
HHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GVNWSKVEAKIKDGSIDQNLGTNRALAEAMSISGTPAFIIGDQILRGAPRDLASLKGFIK
CCCHHHHEEEECCCCCCCCCCCHHHHHHHHHCCCCCCEEECHHHHCCCCHHHHHHHHHHH
DVRAGKSIQ
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA