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The map label for this gene is cynX [H]

Identifier: 145299655

GI number: 145299655

Start: 2925076

End: 2926329

Strand: Direct

Name: cynX [H]

Synonym: ASA_2729

Alternate gene names: 145299655

Gene position: 2925076-2926329 (Clockwise)

Preceding gene: 145299654

Following gene: 145299657

Centisome position: 62.2

GC content: 66.99

Gene sequence:

>1254_bases
ATGAGTAAGGACCTGCCCGCCAGCACTCTGCACCACAGCAAGCAGGATCTGGCCCTGCTGGTGCTGGTGATCCTGATTGG
CCTCAATCTGCGTCCCTTTCTCACCGCCATAGGGCCGCTGGCCCAAGCGATAGACAACCGCCTTGGCCTCGGCATGGATA
CCCTGGCCTGGCTCACCCTGCTGCCCCTCTGGCTCATCGGCGTCGGCGTGCTGATAACCCCTGGCCTGCGCCGCCTCACG
GGTCCAAGTCAACTGCTGGGGGCCGCTCTCTTGCTGCTGGGGATGGGAAACGCCATGCGCTTTGATGCCCAGAGCGGCGC
CCTGCTGATCGCCAGCGCGGCGCTTTGTGGCCTCGGCTCGGCGCTGGTGCAAGGGGTGCTACCCGGCCTTATCAAGCAGA
GCTTCGCCCACAAGGTGCCACTGGTGATGGGGATCTTCTCGGCCTGCATGATGGGGGGCGGAGCGCTGGGAGCCAGCCTC
ACCCCGCAACTGGTGGCAAGCCTCGACTGGTCGCGGGCGCTCGCTCTGTGGAGTCTGCCGGTACTGTTGGCCATGGTCTG
GCTAGGGTGGAAAGTCCGCCTGCCAAGCGCCGCCGTGGTGGCTATTCCCCACGGCGAGCAACGGCTGATCACCCTGCCCC
GCAGCTGGTTGCTGATCGGCTGCTTTGGCATCATCAACAGCGGCTACGGCATTGTCGTCGCCTGGCTGGCGCCCGCCTAT
ATGGCGCAAGGGTGGAGCGCCCAGCAGGGGGGCGAGCTGGTGGCCTGGCTGGCGCTGGCGCAGACAGCCAGCGGTCTCGG
CCTGCCCCTGCTGGCGGCACGCAACACAGACCGGCGCCCCTGGATGGGCCTTGCCATCATCATGCAGGTAGCAGGATTTG
GCGGCCTCTGGCTCGCGCCACAAGCCGCCCCCATCCTCTGGTGCATGCTGTGCGGCGCCGGGCTTGGCGGCAGCTTCTCC
CTCATCATGGTGATAGCGCTGGATCACCTACCTGACCCACGCCGTGCCGGCACCCTCAGCGCCCTGATGCAGGGGTTCGG
CTTTATGCTGGCGGCAACCGGCCCCTGGGTTGCGGCCCGCCTCCATCATCTGAGTGGCGACTTCGCGGCCGCCTGGCAGT
GGCAACTGGGGGGATTGGCGCTGATGAGCCTGCTGGTGCTGCGCCTGGACCCGCGCGGCTATGCCAAGGTGATGAGGTTG
CCAACCCCAGCGCCTGCGGCCAGCGGTACGGCACAAAGCAAAACACCGGCCTGA

Upstream 100 bases:

>100_bases
CGACTGCCCCTTAACCCGCCACCTCTGCCCCTCATCAAACTACCAGTCTCCCTCGGCGCCACCGCGCTCTATGGAGACAA
CTCAGAGGCGGAACTAGCCC

Downstream 100 bases:

>100_bases
GGCCGGTGTTTTTGGGGATAACAAGGGGAGGCTGACGCCGCTCAGGATTGCGCCTCAGCGCCCCTTCTTCTGGCGGCCGG
ACTGACCGGCGCGCGGTTTG

Product: cyanate transport protein CynX

Products: Proton [Cytoplasm]; Cyanate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSKDLPASTLHHSKQDLALLVLVILIGLNLRPFLTAIGPLAQAIDNRLGLGMDTLAWLTLLPLWLIGVGVLITPGLRRLT
GPSQLLGAALLLLGMGNAMRFDAQSGALLIASAALCGLGSALVQGVLPGLIKQSFAHKVPLVMGIFSACMMGGGALGASL
TPQLVASLDWSRALALWSLPVLLAMVWLGWKVRLPSAAVVAIPHGEQRLITLPRSWLLIGCFGIINSGYGIVVAWLAPAY
MAQGWSAQQGGELVAWLALAQTASGLGLPLLAARNTDRRPWMGLAIIMQVAGFGGLWLAPQAAPILWCMLCGAGLGGSFS
LIMVIALDHLPDPRRAGTLSALMQGFGFMLAATGPWVAARLHHLSGDFAAAWQWQLGGLALMSLLVLRLDPRGYAKVMRL
PTPAPAASGTAQSKTPA

Sequences:

>Translated_417_residues
MSKDLPASTLHHSKQDLALLVLVILIGLNLRPFLTAIGPLAQAIDNRLGLGMDTLAWLTLLPLWLIGVGVLITPGLRRLT
GPSQLLGAALLLLGMGNAMRFDAQSGALLIASAALCGLGSALVQGVLPGLIKQSFAHKVPLVMGIFSACMMGGGALGASL
TPQLVASLDWSRALALWSLPVLLAMVWLGWKVRLPSAAVVAIPHGEQRLITLPRSWLLIGCFGIINSGYGIVVAWLAPAY
MAQGWSAQQGGELVAWLALAQTASGLGLPLLAARNTDRRPWMGLAIIMQVAGFGGLWLAPQAAPILWCMLCGAGLGGSFS
LIMVIALDHLPDPRRAGTLSALMQGFGFMLAATGPWVAARLHHLSGDFAAAWQWQLGGLALMSLLVLRLDPRGYAKVMRL
PTPAPAASGTAQSKTPA
>Mature_416_residues
SKDLPASTLHHSKQDLALLVLVILIGLNLRPFLTAIGPLAQAIDNRLGLGMDTLAWLTLLPLWLIGVGVLITPGLRRLTG
PSQLLGAALLLLGMGNAMRFDAQSGALLIASAALCGLGSALVQGVLPGLIKQSFAHKVPLVMGIFSACMMGGGALGASLT
PQLVASLDWSRALALWSLPVLLAMVWLGWKVRLPSAAVVAIPHGEQRLITLPRSWLLIGCFGIINSGYGIVVAWLAPAYM
AQGWSAQQGGELVAWLALAQTASGLGLPLLAARNTDRRPWMGLAIIMQVAGFGGLWLAPQAAPILWCMLCGAGLGGSFSL
IMVIALDHLPDPRRAGTLSALMQGFGFMLAATGPWVAARLHHLSGDFAAAWQWQLGGLALMSLLVLRLDPRGYAKVMRLP
TPAPAASGTAQSKTPA

Specific function: This protein is part of an active transport system that transports exogenous cyanate into E.coli cells [H]

COG id: COG2807

COG function: function code P; Cyanate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Cyanate porter (TC 2.A.1.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786536, Length=384, Percent_Identity=38.8020833333333, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1788092, Length=388, Percent_Identity=30.1546391752577, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004747
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43664; Mature: 43533

Theoretical pI: Translated: 10.75; Mature: 10.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDLPASTLHHSKQDLALLVLVILIGLNLRPFLTAIGPLAQAIDNRLGLGMDTLAWLTL
CCCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LPLWLIGVGVLITPGLRRLTGPSQLLGAALLLLGMGNAMRFDAQSGALLIASAALCGLGS
HHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHH
ALVQGVLPGLIKQSFAHKVPLVMGIFSACMMGGGALGASLTPQLVASLDWSRALALWSLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHH
VLLAMVWLGWKVRLPSAAVVAIPHGEQRLITLPRSWLLIGCFGIINSGYGIVVAWLAPAY
HHHHHHHHCCEEECCCEEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCCEEHHHHHHHH
MAQGWSAQQGGELVAWLALAQTASGLGLPLLAARNTDRRPWMGLAIIMQVAGFGGLWLAP
HHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEECC
QAAPILWCMLCGAGLGGSFSLIMVIALDHLPDPRRAGTLSALMQGFGFMLAATGPWVAAR
CHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEECCCHHHHHH
LHHLSGDFAAAWQWQLGGLALMSLLVLRLDPRGYAKVMRLPTPAPAASGTAQSKTPA
HHHHCCCHHEEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKDLPASTLHHSKQDLALLVLVILIGLNLRPFLTAIGPLAQAIDNRLGLGMDTLAWLTL
CCCCCCHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LPLWLIGVGVLITPGLRRLTGPSQLLGAALLLLGMGNAMRFDAQSGALLIASAALCGLGS
HHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHH
ALVQGVLPGLIKQSFAHKVPLVMGIFSACMMGGGALGASLTPQLVASLDWSRALALWSLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHH
VLLAMVWLGWKVRLPSAAVVAIPHGEQRLITLPRSWLLIGCFGIINSGYGIVVAWLAPAY
HHHHHHHHCCEEECCCEEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCCEEHHHHHHHH
MAQGWSAQQGGELVAWLALAQTASGLGLPLLAARNTDRRPWMGLAIIMQVAGFGGLWLAP
HHCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEECC
QAAPILWCMLCGAGLGGSFSLIMVIALDHLPDPRRAGTLSALMQGFGFMLAATGPWVAAR
CHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEECCCHHHHHH
LHHLSGDFAAAWQWQLGGLALMSLLVLRLDPRGYAKVMRLPTPAPAASGTAQSKTPA
HHHHCCCHHEEEEHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Cyanate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Cyanate [Periplasm] = Proton [Cytoplasm] + Cyanate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3049588; 9278503 [H]