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The map label for this gene is ptrB [H]

Identifier: 145299622

GI number: 145299622

Start: 2890923

End: 2892854

Strand: Direct

Name: ptrB [H]

Synonym: ASA_2696

Alternate gene names: 145299622

Gene position: 2890923-2892854 (Clockwise)

Preceding gene: 145299621

Following gene: 145299623

Centisome position: 61.48

GC content: 67.18

Gene sequence:

>1932_bases
ATGAAGGGCGACACGGCGCGGCGCGATCCCTATGGCGGCTGGCGCGACGACAGTCGCCAGGATCCCGCCCTGCTGGCCAT
GCTGGCCGAGCAGAACCGCTGGACCGAGCAGCAGCTCGCCAGCCAGCGGCCGCTGGAGCAGGCGCTGCAAGCCGAGTGGC
AGACACAGCCGCGCGGCGAGCCCATGCCCGCCGAGTGGCACACTGAAGCGGGCAGCCAGTGGCGGATGGAGGCCGACGGC
AGCCTGTGGCAACGGGCTGATGACAAGGCGCAGCCCCGTCAGCGACTGGCGCCGCGTCAACCGGCGAGCGGCTATTACGA
GCTCGCCGGCTGGGCACTGCACCCGAACGGACGCTGGCTGGCCCTGGCCGAAGATCTGCGTGGCGATCTGGACTACCGCA
TCACCCTGCTGGATCTGGATAGCGGCAAGACACAAACCACCCTGGCGCACAGGGCCGCCGATCTGCTCTGGAGCCTGGAC
GGCAAGACCCTCTACACCCTTGCCAACGAGCGCCGCACCCTGCGCCCATGGCAGCTGTGGGCCTGGCAGGATGGCAAGGA
GCGGCTAGTACACCAGGAGGCCAATCCCGCCTGGCTGCTCAGCCTCTATGGCACCACGGACAAACGCCACCTGCTGCTGC
AGAGCAACAACCACGACAGCTCGGAGCAGTACCTGCTGGACGAGGGAACCCCCTCTCTGCTCAAGGCCCGCCAGGCCGGT
GTCGAGTACTACCTGGATACCCAAGGGGAGCGAGTGCTCATCAAGAGCAACAAAGATGGTGCCCTCGGCCTTTATCAGGT
GACCAGTCTGGCACAGGTGGCCGAGGGGCACTGGCAACCCCTCTGGTCCGGCGAGAACAAGAGCCTGGAGAAGTGGCGCC
TGTTTGCCGACCATACGGTCCTGCAATACCGCAAGGCAGGGGACGACTGGCTCGATGTGCTGGATTCAAGCGGCCAGCTC
AGCCAGCGCGTGCATCTCACCGAGGGCGCTGGCACGGCCTGGATCCAGGGTGCTCATGACCCGGCCAGCCAGCAGATCCT
GATCCGCAGGCAAGGGATGGCCGAGCCGCCCCACCAACGCTGGCTCAATCTGGCCAGCGGTCAGTGGCAAGCTGGCGCGC
AGACGCAGGCACCCTCCCCCTACCGAAGCGAGCGACGCTGGGTGCTGGGCAAGGATGGGGTCAAGGTGCCCGTCTCTCTG
GTGTGGCGCACCGACATCACCAAGCCCAAGGCGCTGCTGCTCTACGGCTACGGCGCCTATGGCACCCCTATGCGCCCCTA
CTACCAGCCCCAGGTGCTGAGCCTGCTGGATCGCGGTTTTGTCTACGCCATCGCTCACGTGCGCGGCGGCGGCATGCTGG
GAGATGACTGGTATCTGGCAGGGCGCGGCCGGCAAAAACAGCACAGCGTGGACGACTTCCTGACCGTGGCAGAGGCGCTG
GCCCGAGATCCGGCCATTGATCCTGCCCGGCTGTTCGCCATGGGCGGCAGTGCCGGCGGTCTGCTGGTGGCGGCGGCGCT
CAATCAGGCGCCAACCCGCTTTGCCGGCGCCGTGTTGCAGGTGCCCTTCGTCGATCTGCTCGGCACCATGAGCGATCCCG
AACTGCCGCTCACCCGCCAGGAGTACGCCGAGTGGGGCAATCCGGCCATTCCCGCCGACTATGCTGCCATGCGTCGCCTG
AGCCCCTATGACAACCTGCAACGGCAGCCCTATCCCCCGGTTTATGTGACGGCCGGGCTGCACGACAGCCAGGTGCCTTA
CTGGGAGCCGCTCAAATGGGTCGCCCGGCTGCGGGAGCACAGCACGGGCACGGGCCCCTATCTGCTGAGTACGGCTCTCG
ACAGCGGCCACCAGGCCAGCACCGGCAAGGCCCACCAGCAGGCAGCGCGCGAGTATGCCTTCCTGCTCACCCTGGCTGGC
GTTACCCGCTGA

Upstream 100 bases:

>100_bases
TCTGCTGGCCAATCCGGTGGCCTCCCCCGCCGAGGCCGCAATGACGGCAACCACCACGGCGCCACAGAGCGCGCCAGCCA
TTGCCAAACGTCCCCTGCTG

Downstream 100 bases:

>100_bases
TGGCGCATCCTTTTCTCATTTTTGTGTTGGAGTAAACCATGAAACCCTCTTCCCTGGCCCTCTGGCTGGCGGCAACCTTG
CTCTCACAGCCCCTGCTGGC

Product: protease II

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MKGDTARRDPYGGWRDDSRQDPALLAMLAEQNRWTEQQLASQRPLEQALQAEWQTQPRGEPMPAEWHTEAGSQWRMEADG
SLWQRADDKAQPRQRLAPRQPASGYYELAGWALHPNGRWLALAEDLRGDLDYRITLLDLDSGKTQTTLAHRAADLLWSLD
GKTLYTLANERRTLRPWQLWAWQDGKERLVHQEANPAWLLSLYGTTDKRHLLLQSNNHDSSEQYLLDEGTPSLLKARQAG
VEYYLDTQGERVLIKSNKDGALGLYQVTSLAQVAEGHWQPLWSGENKSLEKWRLFADHTVLQYRKAGDDWLDVLDSSGQL
SQRVHLTEGAGTAWIQGAHDPASQQILIRRQGMAEPPHQRWLNLASGQWQAGAQTQAPSPYRSERRWVLGKDGVKVPVSL
VWRTDITKPKALLLYGYGAYGTPMRPYYQPQVLSLLDRGFVYAIAHVRGGGMLGDDWYLAGRGRQKQHSVDDFLTVAEAL
ARDPAIDPARLFAMGGSAGGLLVAAALNQAPTRFAGAVLQVPFVDLLGTMSDPELPLTRQEYAEWGNPAIPADYAAMRRL
SPYDNLQRQPYPPVYVTAGLHDSQVPYWEPLKWVARLREHSTGTGPYLLSTALDSGHQASTGKAHQQAAREYAFLLTLAG
VTR

Sequences:

>Translated_643_residues
MKGDTARRDPYGGWRDDSRQDPALLAMLAEQNRWTEQQLASQRPLEQALQAEWQTQPRGEPMPAEWHTEAGSQWRMEADG
SLWQRADDKAQPRQRLAPRQPASGYYELAGWALHPNGRWLALAEDLRGDLDYRITLLDLDSGKTQTTLAHRAADLLWSLD
GKTLYTLANERRTLRPWQLWAWQDGKERLVHQEANPAWLLSLYGTTDKRHLLLQSNNHDSSEQYLLDEGTPSLLKARQAG
VEYYLDTQGERVLIKSNKDGALGLYQVTSLAQVAEGHWQPLWSGENKSLEKWRLFADHTVLQYRKAGDDWLDVLDSSGQL
SQRVHLTEGAGTAWIQGAHDPASQQILIRRQGMAEPPHQRWLNLASGQWQAGAQTQAPSPYRSERRWVLGKDGVKVPVSL
VWRTDITKPKALLLYGYGAYGTPMRPYYQPQVLSLLDRGFVYAIAHVRGGGMLGDDWYLAGRGRQKQHSVDDFLTVAEAL
ARDPAIDPARLFAMGGSAGGLLVAAALNQAPTRFAGAVLQVPFVDLLGTMSDPELPLTRQEYAEWGNPAIPADYAAMRRL
SPYDNLQRQPYPPVYVTAGLHDSQVPYWEPLKWVARLREHSTGTGPYLLSTALDSGHQASTGKAHQQAAREYAFLLTLAG
VTR
>Mature_643_residues
MKGDTARRDPYGGWRDDSRQDPALLAMLAEQNRWTEQQLASQRPLEQALQAEWQTQPRGEPMPAEWHTEAGSQWRMEADG
SLWQRADDKAQPRQRLAPRQPASGYYELAGWALHPNGRWLALAEDLRGDLDYRITLLDLDSGKTQTTLAHRAADLLWSLD
GKTLYTLANERRTLRPWQLWAWQDGKERLVHQEANPAWLLSLYGTTDKRHLLLQSNNHDSSEQYLLDEGTPSLLKARQAG
VEYYLDTQGERVLIKSNKDGALGLYQVTSLAQVAEGHWQPLWSGENKSLEKWRLFADHTVLQYRKAGDDWLDVLDSSGQL
SQRVHLTEGAGTAWIQGAHDPASQQILIRRQGMAEPPHQRWLNLASGQWQAGAQTQAPSPYRSERRWVLGKDGVKVPVSL
VWRTDITKPKALLLYGYGAYGTPMRPYYQPQVLSLLDRGFVYAIAHVRGGGMLGDDWYLAGRGRQKQHSVDDFLTVAEAL
ARDPAIDPARLFAMGGSAGGLLVAAALNQAPTRFAGAVLQVPFVDLLGTMSDPELPLTRQEYAEWGNPAIPADYAAMRRL
SPYDNLQRQPYPPVYVTAGLHDSQVPYWEPLKWVARLREHSTGTGPYLLSTALDSGHQASTGKAHQQAAREYAFLLTLAG
VTR

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172438, Length=457, Percent_Identity=27.1334792122538, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI284172431, Length=457, Percent_Identity=27.1334792122538, Blast_Score=156, Evalue=6e-38,
Organism=Homo sapiens, GI284172420, Length=457, Percent_Identity=27.1334792122538, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI284172413, Length=457, Percent_Identity=27.1334792122538, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI70778815, Length=457, Percent_Identity=27.1334792122538, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI108860686, Length=317, Percent_Identity=30.9148264984227, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI108860692, Length=222, Percent_Identity=35.1351351351351, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI41349456, Length=278, Percent_Identity=28.7769784172662, Blast_Score=109, Evalue=6e-24,
Organism=Escherichia coli, GI1788150, Length=667, Percent_Identity=35.232383808096, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24583414, Length=657, Percent_Identity=22.3744292237443, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI221510989, Length=423, Percent_Identity=26.241134751773, Blast_Score=121, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 72167; Mature: 72167

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGDTARRDPYGGWRDDSRQDPALLAMLAEQNRWTEQQLASQRPLEQALQAEWQTQPRGE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCCC
PMPAEWHTEAGSQWRMEADGSLWQRADDKAQPRQRLAPRQPASGYYELAGWALHPNGRWL
CCCCCCCCCCCCCEEEECCCHHHHCCCCCCCHHHHCCCCCCCCCCEEEEEEEECCCCCEE
ALAEDLRGDLDYRITLLDLDSGKTQTTLAHRAADLLWSLDGKTLYTLANERRTLRPWQLW
EEEHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEE
AWQDGKERLVHQEANPAWLLSLYGTTDKRHLLLQSNNHDSSEQYLLDEGTPSLLKARQAG
EECCCHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEECCCCHHHHHHHHCC
VEYYLDTQGERVLIKSNKDGALGLYQVTSLAQVAEGHWQPLWSGENKSLEKWRLFADHTV
CEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LQYRKAGDDWLDVLDSSGQLSQRVHLTEGAGTAWIQGAHDPASQQILIRRQGMAEPPHQR
HHHHHCCCHHHHHHCCCCCCHHEEEEECCCCCEEEECCCCCCHHEEHEECCCCCCCCHHH
WLNLASGQWQAGAQTQAPSPYRSERRWVLGKDGVKVPVSLVWRTDITKPKALLLYGYGAY
HHHCCCCCCCCCCCCCCCCCCHHCCCEEECCCCCCCCEEEEEECCCCCCCEEEEEECCCC
GTPMRPYYQPQVLSLLDRGFVYAIAHVRGGGMLGDDWYLAGRGRQKQHSVDDFLTVAEAL
CCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHH
ARDPAIDPARLFAMGGSAGGLLVAAALNQAPTRFAGAVLQVPFVDLLGTMSDPELPLTRQ
HCCCCCCHHHEEEECCCCCCCHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCHH
EYAEWGNPAIPADYAAMRRLSPYDNLQRQPYPPVYVTAGLHDSQVPYWEPLKWVARLREH
HHHHCCCCCCCHHHHHHHHCCCHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHC
STGTGPYLLSTALDSGHQASTGKAHQQAAREYAFLLTLAGVTR
CCCCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKGDTARRDPYGGWRDDSRQDPALLAMLAEQNRWTEQQLASQRPLEQALQAEWQTQPRGE
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCCC
PMPAEWHTEAGSQWRMEADGSLWQRADDKAQPRQRLAPRQPASGYYELAGWALHPNGRWL
CCCCCCCCCCCCCEEEECCCHHHHCCCCCCCHHHHCCCCCCCCCCEEEEEEEECCCCCEE
ALAEDLRGDLDYRITLLDLDSGKTQTTLAHRAADLLWSLDGKTLYTLANERRTLRPWQLW
EEEHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEE
AWQDGKERLVHQEANPAWLLSLYGTTDKRHLLLQSNNHDSSEQYLLDEGTPSLLKARQAG
EECCCHHHHHHCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCEEECCCCHHHHHHHHCC
VEYYLDTQGERVLIKSNKDGALGLYQVTSLAQVAEGHWQPLWSGENKSLEKWRLFADHTV
CEEEEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
LQYRKAGDDWLDVLDSSGQLSQRVHLTEGAGTAWIQGAHDPASQQILIRRQGMAEPPHQR
HHHHHCCCHHHHHHCCCCCCHHEEEEECCCCCEEEECCCCCCHHEEHEECCCCCCCCHHH
WLNLASGQWQAGAQTQAPSPYRSERRWVLGKDGVKVPVSLVWRTDITKPKALLLYGYGAY
HHHCCCCCCCCCCCCCCCCCCHHCCCEEECCCCCCCCEEEEEECCCCCCCEEEEEECCCC
GTPMRPYYQPQVLSLLDRGFVYAIAHVRGGGMLGDDWYLAGRGRQKQHSVDDFLTVAEAL
CCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHH
ARDPAIDPARLFAMGGSAGGLLVAAALNQAPTRFAGAVLQVPFVDLLGTMSDPELPLTRQ
HCCCCCCHHHEEEECCCCCCCHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCHH
EYAEWGNPAIPADYAAMRRLSPYDNLQRQPYPPVYVTAGLHDSQVPYWEPLKWVARLREH
HHHHCCCCCCCHHHHHHHHCCCHHHCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHC
STGTGPYLLSTALDSGHQASTGKAHQQAAREYAFLLTLAGVTR
CCCCCCEEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]