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The map label for this gene is ahpC [H]

Identifier: 145299558

GI number: 145299558

Start: 2808184

End: 2808750

Strand: Direct

Name: ahpC [H]

Synonym: ASA_2627

Alternate gene names: 145299558

Gene position: 2808184-2808750 (Clockwise)

Preceding gene: 145299557

Following gene: 145299559

Centisome position: 59.72

GC content: 57.32

Gene sequence:

>567_bases
ATGTCTACCTATATCAACACTGAAATCAAGCCGTTCAACGCCACCGCCTACCACAATGGCAAGTTCGTTCAGGTGTCTGA
CGCAGACCTGAAAGGCAAGTGGTCCGTGGTGTTCTTCTACCCGGCTGACTTCACCTTCGTTTGCCCGACCGAGCTGGGTG
ACCTGGCTGACAACTACGCCGAATTCAAGAAACTGGGCGTCGAGATCTACTCCGTCTCCACCGACACCCACTTCACTCAC
AAGGCGTGGCACGACACTTCCGACACCATCCAGAAGATCCAGTATCCGATGATTGGTGACCCGACCGGCGCCATCACCCG
CAACTTCCGCGTCATGATCGAAGAAGCTGGCCTGGCTGACCGCGGCACCTTCGTTATCGACCCGCAAGGCATCATCCAGA
TCGTTGAGATCAACGCTGATGGCATCGGTCGTGACGCGCTGGAACTGCTGCGCAAGGTCAAAGCGGCTCAGTACGTAGCT
TCCCACCCGGGTGAAGTGTGCCCGGCCAAGTGGAAAGAAGGCGACGCCACCCTGGCCCCGTCCCTGGATCTGGTAGGCAA
AATCTAA

Upstream 100 bases:

>100_bases
AGAAAAGCCCCTATGATGAATCCATCGAACGTTAAACGCCTGGTCCGGACAGACTCTTCAATACCAGACAGGCACATGTA
CATCACCAAGGAGCTAATAC

Downstream 100 bases:

>100_bases
GCCTCCCGCTTCCAAGACCGGCCCATTCAAGGGCCGGTCTGCTTTCTGGCCTCCTCTTGGATCATCAGGCCAGTCATCGC
CGACCCGCAATCATTAAGAA

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSTYINTEIKPFNATAYHNGKFVQVSDADLKGKWSVVFFYPADFTFVCPTELGDLADNYAEFKKLGVEIYSVSTDTHFTH
KAWHDTSDTIQKIQYPMIGDPTGAITRNFRVMIEEAGLADRGTFVIDPQGIIQIVEINADGIGRDALELLRKVKAAQYVA
SHPGEVCPAKWKEGDATLAPSLDLVGKI

Sequences:

>Translated_188_residues
MSTYINTEIKPFNATAYHNGKFVQVSDADLKGKWSVVFFYPADFTFVCPTELGDLADNYAEFKKLGVEIYSVSTDTHFTH
KAWHDTSDTIQKIQYPMIGDPTGAITRNFRVMIEEAGLADRGTFVIDPQGIIQIVEINADGIGRDALELLRKVKAAQYVA
SHPGEVCPAKWKEGDATLAPSLDLVGKI
>Mature_187_residues
STYINTEIKPFNATAYHNGKFVQVSDADLKGKWSVVFFYPADFTFVCPTELGDLADNYAEFKKLGVEIYSVSTDTHFTHK
AWHDTSDTIQKIQYPMIGDPTGAITRNFRVMIEEAGLADRGTFVIDPQGIIQIVEINADGIGRDALELLRKVKAAQYVAS
HPGEVCPAKWKEGDATLAPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=45.0867052023121, Blast_Score=155, Evalue=1e-38,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=45.0867052023121, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=42.2857142857143, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=41.7142857142857, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=41.7142857142857, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=41.7142857142857, Blast_Score=144, Evalue=6e-35,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=40.5555555555556, Blast_Score=140, Evalue=5e-34,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=51.3513513513513, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI4758638, Length=167, Percent_Identity=29.3413173652695, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1786822, Length=186, Percent_Identity=73.1182795698925, Blast_Score=303, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=42.3728813559322, Blast_Score=147, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI193204376, Length=182, Percent_Identity=40.1098901098901, Blast_Score=140, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32565831, Length=182, Percent_Identity=40.1098901098901, Blast_Score=140, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=185, Percent_Identity=34.0540540540541, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323613, Length=186, Percent_Identity=34.9462365591398, Blast_Score=122, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6319407, Length=163, Percent_Identity=30.0613496932515, Blast_Score=76, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24656348, Length=173, Percent_Identity=41.6184971098266, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI17864676, Length=173, Percent_Identity=41.6184971098266, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=38.9830508474576, Blast_Score=144, Evalue=5e-35,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=41.1764705882353, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=41.1764705882353, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI21357347, Length=177, Percent_Identity=37.8531073446328, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=30.5194805194805, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI17975518, Length=154, Percent_Identity=29.8701298701299, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=29.1139240506329, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24652436, Length=154, Percent_Identity=29.8701298701299, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20789; Mature: 20658

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTYINTEIKPFNATAYHNGKFVQVSDADLKGKWSVVFFYPADFTFVCPTELGDLADNYA
CCCEECCEECCCCCEEEECCEEEEEECCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHH
EFKKLGVEIYSVSTDTHFTHKAWHDTSDTIQKIQYPMIGDPTGAITRNFRVMIEEAGLAD
HHHHCCEEEEEEECCCCEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCC
RGTFVIDPQGIIQIVEINADGIGRDALELLRKVKAAQYVASHPGEVCPAKWKEGDATLAP
CCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECC
SLDLVGKI
CCHHCCCC
>Mature Secondary Structure 
STYINTEIKPFNATAYHNGKFVQVSDADLKGKWSVVFFYPADFTFVCPTELGDLADNYA
CCEECCEECCCCCEEEECCEEEEEECCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHH
EFKKLGVEIYSVSTDTHFTHKAWHDTSDTIQKIQYPMIGDPTGAITRNFRVMIEEAGLAD
HHHHCCEEEEEEECCCCEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCC
RGTFVIDPQGIIQIVEINADGIGRDALELLRKVKAAQYVASHPGEVCPAKWKEGDATLAP
CCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECC
SLDLVGKI
CCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]