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The map label for this gene is argA [H]

Identifier: 145299510

GI number: 145299510

Start: 2753836

End: 2755164

Strand: Direct

Name: argA [H]

Synonym: ASA_2577

Alternate gene names: 145299510

Gene position: 2753836-2755164 (Clockwise)

Preceding gene: 145299508

Following gene: 145299511

Centisome position: 58.56

GC content: 62.0

Gene sequence:

>1329_bases
GTGCGTGAACGCGAACCCAGCCTGGTCTATGCCTTTCGGCAGTCTACCCCCTATGTCAATGTGCACAGAGGCGCCACCTT
TGTGCTGATGATGGGAGGGGAAGCCATCTGCCACCCCAATTTTGCCAATATCGTCAGCGATATCGCCCTGCTGCAGACAC
TGGGAATTCGTTTGGTGCTGGTGTTCGGTTCACGTCCGCAAAACGACGAGGCACTGGCTCGCGCGGGCATCGAAGCCCAG
TACCACAGGCGGATCCGGGTCACCGATGACGAGAGCTTCGCCATCATCAAACAAGTGTGTGGCGGACTGCAGTACGACAT
CACGGCCCAGCTCTCCATGGGGCTGGCCAACACCCCCATGCAGGAGGCCCGCATCAGCGTGGTGAGTGGCAACTTCGTCA
CCGCCCAGCCACTGGGGGTGGATGATGGCATCGACTTTTGCCACAGCGGTCGGGTACGCCGCATCGACGTGGAGGGGATC
ACCCGCCAGCTGGATCAGAAGGGTCTGGTGCTGATCTCCCCCATCGGCTGCTCGGTCACCGGCGAGAGCTTCAACCTGAG
CTCGGAAGAGGTCGCCCGCCGGGTGGCAGTGGATCTCAAAGCCGACAAGCTTATCTGTTTCAGCAGCACCCAGGGCGTCA
TGGACAGACACGGCGAAGCCATCTCGGAACTCTTCCCCGAGCAGGCCGAGGAGCTGCTGGTGGAGCTGGAGCAGGCGGGG
GAAGAGATGTCAGGCACAGCCCGTTACCTGCGTGCGGCAATTGCCTCCTGCCGGGGCGGCGTGCCCCGCTCCCATCTGGT
GAGCTATCAGGATGACGGCGCCATGTTGCAGGAGCTGTTCAGTCGCGACGGCCTCGGTACCCAGATAGTGCGGGAAAGCG
CCGAGCAGGCCCGCGCCGCCACCATCGAAGACATTGGCGGTATTCTGGATCTCATTCGCCCGCTGGAGGAGGACGGCATT
CTGGTGCGTCGCTCTCGCGAGCAGCTGGAGATGGAAATAGACAAGTTCACCATCATAGAGCGCGACGGCCTCATCATCGG
CTGCGCGGCGCTCTACTGCTTCATGGAAGAGGCGATGGCGGAGATGGCCTGCGTCGCCATTCACCCCGAGTATCGCAACT
CCAATCGGGGGGATCAGCTGGTGGCCAAGGTGGCCGAGCGGGCCAAGCGGCTCGGCATTCGTCGCCTGTTCGTGCTCACT
ACCCGCTCCATTCACTGGTTCCGGGAACGGGGCTTCGATCCGCTGGAGGTGGAAGACCTGCCGGTGGAACGGCAACGGCT
CTACAACTGGCAGCGCCGCTCCAAGGTTTTGTCAAAAACCATTTCGTAA

Upstream 100 bases:

>100_bases
AATGGTGGCATAAAATGGCAAAATCAATATTTAGTCTTTATTTGTGAATTTATTTTCATATATTGAGCCCATTGCTGTTT
TTTTATGGAAGAAGCCTCAA

Downstream 100 bases:

>100_bases
CTTGTTGATCTTGTGCCGAGTTGTCGTCGATTGTTAACTTTTTCACAATCTCGATTGACAGTGCAATCCAGCACAGGGTA
TTTCTAATTGCACTCCACCG

Product: N-acetylglutamate synthase

Products: NA

Alternate protein names: N-acetylglutamate synthase; AGS; NAGS [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MREREPSLVYAFRQSTPYVNVHRGATFVLMMGGEAICHPNFANIVSDIALLQTLGIRLVLVFGSRPQNDEALARAGIEAQ
YHRRIRVTDDESFAIIKQVCGGLQYDITAQLSMGLANTPMQEARISVVSGNFVTAQPLGVDDGIDFCHSGRVRRIDVEGI
TRQLDQKGLVLISPIGCSVTGESFNLSSEEVARRVAVDLKADKLICFSSTQGVMDRHGEAISELFPEQAEELLVELEQAG
EEMSGTARYLRAAIASCRGGVPRSHLVSYQDDGAMLQELFSRDGLGTQIVRESAEQARAATIEDIGGILDLIRPLEEDGI
LVRRSREQLEMEIDKFTIIERDGLIIGCAALYCFMEEAMAEMACVAIHPEYRNSNRGDQLVAKVAERAKRLGIRRLFVLT
TRSIHWFRERGFDPLEVEDLPVERQRLYNWQRRSKVLSKTIS

Sequences:

>Translated_442_residues
MREREPSLVYAFRQSTPYVNVHRGATFVLMMGGEAICHPNFANIVSDIALLQTLGIRLVLVFGSRPQNDEALARAGIEAQ
YHRRIRVTDDESFAIIKQVCGGLQYDITAQLSMGLANTPMQEARISVVSGNFVTAQPLGVDDGIDFCHSGRVRRIDVEGI
TRQLDQKGLVLISPIGCSVTGESFNLSSEEVARRVAVDLKADKLICFSSTQGVMDRHGEAISELFPEQAEELLVELEQAG
EEMSGTARYLRAAIASCRGGVPRSHLVSYQDDGAMLQELFSRDGLGTQIVRESAEQARAATIEDIGGILDLIRPLEEDGI
LVRRSREQLEMEIDKFTIIERDGLIIGCAALYCFMEEAMAEMACVAIHPEYRNSNRGDQLVAKVAERAKRLGIRRLFVLT
TRSIHWFRERGFDPLEVEDLPVERQRLYNWQRRSKVLSKTIS
>Mature_442_residues
MREREPSLVYAFRQSTPYVNVHRGATFVLMMGGEAICHPNFANIVSDIALLQTLGIRLVLVFGSRPQNDEALARAGIEAQ
YHRRIRVTDDESFAIIKQVCGGLQYDITAQLSMGLANTPMQEARISVVSGNFVTAQPLGVDDGIDFCHSGRVRRIDVEGI
TRQLDQKGLVLISPIGCSVTGESFNLSSEEVARRVAVDLKADKLICFSSTQGVMDRHGEAISELFPEQAEELLVELEQAG
EEMSGTARYLRAAIASCRGGVPRSHLVSYQDDGAMLQELFSRDGLGTQIVRESAEQARAATIEDIGGILDLIRPLEEDGI
LVRRSREQLEMEIDKFTIIERDGLIIGCAALYCFMEEAMAEMACVAIHPEYRNSNRGDQLVAKVAERAKRLGIRRLFVLT
TRSIHWFRERGFDPLEVEDLPVERQRLYNWQRRSKVLSKTIS

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=437, Percent_Identity=62.0137299771167, Blast_Score=578, Evalue=1e-166,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR001048
- InterPro:   IPR010167 [H]

Pfam domain/function: PF00696 AA_kinase; PF00583 Acetyltransf_1 [H]

EC number: =2.3.1.1 [H]

Molecular weight: Translated: 49347; Mature: 49347

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREREPSLVYAFRQSTPYVNVHRGATFVLMMGGEAICHPNFANIVSDIALLQTLGIRLVL
CCCCCCCEEEEEECCCCEEEEECCCEEEEEECCCEEECCCHHHHHHHHHHHHHHCEEEEE
VFGSRPQNDEALARAGIEAQYHRRIRVTDDESFAIIKQVCGGLQYDITAQLSMGLANTPM
EECCCCCCHHHHHHHCCCHHHCCEEEECCCCHHHHHHHHHCCCCEEEEHHEECCCCCCCH
QEARISVVSGNFVTAQPLGVDDGIDFCHSGRVRRIDVEGITRQLDQKGLVLISPIGCSVT
HHHEEEEEECCEEEECCCCCCCCCHHHHCCCEEEEEHHHHHHHHCCCCEEEEECCCCEEC
GESFNLSSEEVARRVAVDLKADKLICFSSTQGVMDRHGEAISELFPEQAEELLVELEQAG
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHC
EEMSGTARYLRAAIASCRGGVPRSHLVSYQDDGAMLQELFSRDGLGTQIVRESAEQARAA
HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TIEDIGGILDLIRPLEEDGILVRRSREQLEMEIDKFTIIERDGLIIGCAALYCFMEEAMA
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHEEEEECCCCEEHHHHHHHHHHHHHH
EMACVAIHPEYRNSNRGDQLVAKVAERAKRLGIRRLFVLTTRSIHWFRERGFDPLEVEDL
HHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCHHHEEEEHHHHHHHHHHCCCCCCCCCCC
PVERQRLYNWQRRSKVLSKTIS
CCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MREREPSLVYAFRQSTPYVNVHRGATFVLMMGGEAICHPNFANIVSDIALLQTLGIRLVL
CCCCCCCEEEEEECCCCEEEEECCCEEEEEECCCEEECCCHHHHHHHHHHHHHHCEEEEE
VFGSRPQNDEALARAGIEAQYHRRIRVTDDESFAIIKQVCGGLQYDITAQLSMGLANTPM
EECCCCCCHHHHHHHCCCHHHCCEEEECCCCHHHHHHHHHCCCCEEEEHHEECCCCCCCH
QEARISVVSGNFVTAQPLGVDDGIDFCHSGRVRRIDVEGITRQLDQKGLVLISPIGCSVT
HHHEEEEEECCEEEECCCCCCCCCHHHHCCCEEEEEHHHHHHHHCCCCEEEEECCCCEEC
GESFNLSSEEVARRVAVDLKADKLICFSSTQGVMDRHGEAISELFPEQAEELLVELEQAG
CCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHC
EEMSGTARYLRAAIASCRGGVPRSHLVSYQDDGAMLQELFSRDGLGTQIVRESAEQARAA
HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHH
TIEDIGGILDLIRPLEEDGILVRRSREQLEMEIDKFTIIERDGLIIGCAALYCFMEEAMA
HHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHEEEEECCCCEEHHHHHHHHHHHHHH
EMACVAIHPEYRNSNRGDQLVAKVAERAKRLGIRRLFVLTTRSIHWFRERGFDPLEVEDL
HHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCHHHEEEEHHHHHHHHHHCCCCCCCCCCC
PVERQRLYNWQRRSKVLSKTIS
CCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA