Click here to switch to the map view.

The map label for this gene is ahe2 [H]

Identifier: 145299476

GI number: 145299476

Start: 2711155

End: 2713032

Strand: Direct

Name: ahe2 [H]

Synonym: ASA_2540

Alternate gene names: 145299476

Gene position: 2711155-2713032 (Clockwise)

Preceding gene: 145299475

Following gene: 145299477

Centisome position: 57.65

GC content: 63.68

Gene sequence:

>1878_bases
ATGAGAAAAACATCGTTGGCGTTGGCAATCTCGGCCCTGCTCTCGGCCCTGCCTATCGCTTCAGTTCAGGCTAATGAGAG
TTGCACCCCACTCACCGGCAAAGAGGCCGGACTCGATACCGGCCGCAGCAGCGCAGTCCGTTGTCTGCCCGGCATCAATC
CCCTGCAGGACCAGCAGTGGCACCTGCTCAACAGCGGCCAGAATGCCTTCAGCCCTCGCGGCGGCATGGCGGGCAATGAT
CTCAACCTCTGGTGGGCACACCGCACCGAAGTATTGGGTCAGGGCATCAATGTGGCCGTGGTGGACGATGGCCTAGCCAT
AGCGCACCCGGATCTGGCCGACAATGTGCGCCCCGGCTCCAAAAACGTGGTGACCGGTGGCAGCGATCCTACCCCGACCG
ATCCGGACAGTGCCCACGGCACTTCGGTATCCGGCATCATAGCCGCGGTGGACAACAGCATAGGCACCCTGGGGGTAGCC
CCCCGCGTCCAATTGCAAGGCTTCAACCTGCTTGATGACAACAGCCAGCAGTTGCAAAAAGATTGGCTCTACGCCCTTGG
CGGCAACGCCGTCACCGCAGACAACCGGGTCTTCAACCAGAGTTACGGCATGAGCCTGGTCGATCCTGAAGGGGCCAACG
GGCTGGATCAGGTACAGCTCGATCGCCTGTTCGAACAGCGGACCCAGCAGGCGCAAGGCGCGGCCTATATCAAGGCGGCG
GGCAACGGCTTCAGCCGTATTGCTGCTGGCAACTATGTGCTCAACCGCACCGGCAACCTGCCCAAGCTGCCGTTTGAGAA
CAGCAATATAGATCCCTCCAACAGCAACTTCTGGAACCTGGTGGTGAGCGCCATCAACGCGGACGGAGTGCGTTCTTCCT
ACTCCAGCGTAGGCAGCAACGTCTTCCTGAGCGCCCCCGGCGGGGAATACGGCACGGATGCGCCCGCCATGGTGACCACG
GATCTGCCCGGCTGCGACATGGGTTACAACCGGGTGGACGATCCCAGCACCAACCGGCTGCACAACAACCCGCAACTGGA
TGCCAGCTGCGACTACAACGGTGTGATGAACGGCACCTCCTCGGCGACTCCGAACACCACAGGCGCCATGGCGCTGCTGA
TGTCCGCCTACCCGGACTTGTCGGTGCGGGATCTGCGCGACCTGCTGGCCCGCAACGCCACCCGGCTCGACGCCAATCAG
GGGCCCGTGCAGATAAACTACACGGCCGCCAACGGCCAGCGCCGCCAGGTGACGGGTCTGGAGGGATGGGAGCGCAACGC
GGCCGGCCTCTGGTACAGCCCGAGCTATGGTTTCGGCCTGGTGGATGTGAACAAGACCCTGGCCAGCGCCGCCAGCCACG
AACCGCTGCCACCACTGGTGCAGTTGCCCTGGCAAAAGGTAACGGTACGGGATCGCGCCGTCGGCGCCATCCCGGATGTG
GGCAGCAGCCCGACCCGCTCCAGCACGCAGGTCGATCAGCCATTGACGGTCGAGGCCGTGCAGGTGATGGTGAGCCTGGA
TCACCAGCGGCTGCCCGACCTGCTGATCGAACTGGTCTCGCCATCCGGTACCCGCAGCGTGTTGCTCAACCCCAACAACA
GCCTGGTGGGACAATCCCTCGACCGGCAGCAGCTGGGCTATGTGCGCACCAAGGGGCTGCGTGACATGCGCATGCTCTCC
CACAAGTTCTACGGCGAACCGGCTCATGGCGAGTGGCGCCTGGAGGTGACCGACGTGGCCAATGGCAGCCGCCAAGTCTC
GCTGCTCGATCGCAGAACCAACACCCGCAGTACCCTGACCGAGCGCAACAACAGCCAGCCGGGTCAACTGCTCGACTGGT
CCCTGCGGGTACTCGGTCACGACGCAGCCCGTTCCTGA

Upstream 100 bases:

>100_bases
CCTTGTCCCAGAACTGAAATGAGCGCTTTTTGGCTCTGTTTTTCCCGTGTATAGATGCCAGTCGCACCCAGGACGGTGCG
ATATAAGATGGAGTTTATAA

Downstream 100 bases:

>100_bases
TCACAGAGGAGTCATAACATGAAACACAGCTTACTCAGCCTTGCCTTGGCAAGCCTGCTGGCCTCGGTCTGCGTGCACGC
AACGGCCGACGAATCGGTGG

Product: serine protease Ahe2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MRKTSLALAISALLSALPIASVQANESCTPLTGKEAGLDTGRSSAVRCLPGINPLQDQQWHLLNSGQNAFSPRGGMAGND
LNLWWAHRTEVLGQGINVAVVDDGLAIAHPDLADNVRPGSKNVVTGGSDPTPTDPDSAHGTSVSGIIAAVDNSIGTLGVA
PRVQLQGFNLLDDNSQQLQKDWLYALGGNAVTADNRVFNQSYGMSLVDPEGANGLDQVQLDRLFEQRTQQAQGAAYIKAA
GNGFSRIAAGNYVLNRTGNLPKLPFENSNIDPSNSNFWNLVVSAINADGVRSSYSSVGSNVFLSAPGGEYGTDAPAMVTT
DLPGCDMGYNRVDDPSTNRLHNNPQLDASCDYNGVMNGTSSATPNTTGAMALLMSAYPDLSVRDLRDLLARNATRLDANQ
GPVQINYTAANGQRRQVTGLEGWERNAAGLWYSPSYGFGLVDVNKTLASAASHEPLPPLVQLPWQKVTVRDRAVGAIPDV
GSSPTRSSTQVDQPLTVEAVQVMVSLDHQRLPDLLIELVSPSGTRSVLLNPNNSLVGQSLDRQQLGYVRTKGLRDMRMLS
HKFYGEPAHGEWRLEVTDVANGSRQVSLLDRRTNTRSTLTERNNSQPGQLLDWSLRVLGHDAARS

Sequences:

>Translated_625_residues
MRKTSLALAISALLSALPIASVQANESCTPLTGKEAGLDTGRSSAVRCLPGINPLQDQQWHLLNSGQNAFSPRGGMAGND
LNLWWAHRTEVLGQGINVAVVDDGLAIAHPDLADNVRPGSKNVVTGGSDPTPTDPDSAHGTSVSGIIAAVDNSIGTLGVA
PRVQLQGFNLLDDNSQQLQKDWLYALGGNAVTADNRVFNQSYGMSLVDPEGANGLDQVQLDRLFEQRTQQAQGAAYIKAA
GNGFSRIAAGNYVLNRTGNLPKLPFENSNIDPSNSNFWNLVVSAINADGVRSSYSSVGSNVFLSAPGGEYGTDAPAMVTT
DLPGCDMGYNRVDDPSTNRLHNNPQLDASCDYNGVMNGTSSATPNTTGAMALLMSAYPDLSVRDLRDLLARNATRLDANQ
GPVQINYTAANGQRRQVTGLEGWERNAAGLWYSPSYGFGLVDVNKTLASAASHEPLPPLVQLPWQKVTVRDRAVGAIPDV
GSSPTRSSTQVDQPLTVEAVQVMVSLDHQRLPDLLIELVSPSGTRSVLLNPNNSLVGQSLDRQQLGYVRTKGLRDMRMLS
HKFYGEPAHGEWRLEVTDVANGSRQVSLLDRRTNTRSTLTERNNSQPGQLLDWSLRVLGHDAARS
>Mature_625_residues
MRKTSLALAISALLSALPIASVQANESCTPLTGKEAGLDTGRSSAVRCLPGINPLQDQQWHLLNSGQNAFSPRGGMAGND
LNLWWAHRTEVLGQGINVAVVDDGLAIAHPDLADNVRPGSKNVVTGGSDPTPTDPDSAHGTSVSGIIAAVDNSIGTLGVA
PRVQLQGFNLLDDNSQQLQKDWLYALGGNAVTADNRVFNQSYGMSLVDPEGANGLDQVQLDRLFEQRTQQAQGAAYIKAA
GNGFSRIAAGNYVLNRTGNLPKLPFENSNIDPSNSNFWNLVVSAINADGVRSSYSSVGSNVFLSAPGGEYGTDAPAMVTT
DLPGCDMGYNRVDDPSTNRLHNNPQLDASCDYNGVMNGTSSATPNTTGAMALLMSAYPDLSVRDLRDLLARNATRLDANQ
GPVQINYTAANGQRRQVTGLEGWERNAAGLWYSPSYGFGLVDVNKTLASAASHEPLPPLVQLPWQKVTVRDRAVGAIPDV
GSSPTRSSTQVDQPLTVEAVQVMVSLDHQRLPDLLIELVSPSGTRSVLLNPNNSLVGQSLDRQQLGYVRTKGLRDMRMLS
HKFYGEPAHGEWRLEVTDVANGSRQVSLLDRRTNTRSTLTERNNSQPGQLLDWSLRVLGHDAARS

Specific function: Agent of furonculosis [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI299523015, Length=561, Percent_Identity=26.2032085561497, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI20336246, Length=561, Percent_Identity=26.2032085561497, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI20336244, Length=548, Percent_Identity=24.0875912408759, Blast_Score=110, Evalue=6e-24,
Organism=Homo sapiens, GI20336180, Length=582, Percent_Identity=24.2268041237113, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI4505577, Length=582, Percent_Identity=24.2268041237113, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI20336184, Length=582, Percent_Identity=24.2268041237113, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI20336182, Length=582, Percent_Identity=24.2268041237113, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI27894285, Length=582, Percent_Identity=24.5704467353952, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI20336188, Length=547, Percent_Identity=24.1316270566728, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI4505579, Length=538, Percent_Identity=24.5353159851301, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI20336190, Length=547, Percent_Identity=24.1316270566728, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI20336242, Length=542, Percent_Identity=24.5387453874539, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI76443679, Length=535, Percent_Identity=24.4859813084112, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI295424143, Length=542, Percent_Identity=24.5387453874539, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI20336248, Length=558, Percent_Identity=25.089605734767, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988312, Length=541, Percent_Identity=24.9537892791128, Blast_Score=112, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71988308, Length=541, Percent_Identity=24.9537892791128, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988321, Length=541, Percent_Identity=24.7689463955638, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988315, Length=541, Percent_Identity=24.7689463955638, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71988297, Length=541, Percent_Identity=24.7689463955638, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71988301, Length=541, Percent_Identity=24.7689463955638, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71987206, Length=541, Percent_Identity=23.6598890942699, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25141268, Length=547, Percent_Identity=23.9488117001828, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71983555, Length=436, Percent_Identity=23.8532110091743, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17505240, Length=488, Percent_Identity=26.2295081967213, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71987215, Length=467, Percent_Identity=22.0556745182013, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324091, Length=591, Percent_Identity=24.3654822335025, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24642488, Length=583, Percent_Identity=25.2144082332762, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24642484, Length=583, Percent_Identity=25.2144082332762, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24642486, Length=583, Percent_Identity=25.2144082332762, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281360987, Length=583, Percent_Identity=25.2144082332762, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24642494, Length=583, Percent_Identity=25.2144082332762, Blast_Score=109, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24642490, Length=583, Percent_Identity=25.2144082332762, Blast_Score=109, Evalue=7e-24,
Organism=Drosophila melanogaster, GI45555723, Length=583, Percent_Identity=25.2144082332762, Blast_Score=109, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24642492, Length=583, Percent_Identity=25.2144082332762, Blast_Score=109, Evalue=7e-24,
Organism=Drosophila melanogaster, GI17136192, Length=568, Percent_Identity=22.7112676056338, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24650056, Length=536, Percent_Identity=24.6268656716418, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24650058, Length=536, Percent_Identity=24.6268656716418, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24650060, Length=536, Percent_Identity=24.6268656716418, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45553513, Length=536, Percent_Identity=24.6268656716418, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI45553515, Length=536, Percent_Identity=24.6268656716418, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17864552, Length=522, Percent_Identity=24.904214559387, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI281360985, Length=123, Percent_Identity=36.5853658536585, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 66891; Mature: 66891

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKTSLALAISALLSALPIASVQANESCTPLTGKEAGLDTGRSSAVRCLPGINPLQDQQW
CCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCE
HLLNSGQNAFSPRGGMAGNDLNLWWAHRTEVLGQGINVAVVDDGLAIAHPDLADNVRPGS
EEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCEEEEEECCEEEECCCHHCCCCCCC
KNVVTGGSDPTPTDPDSAHGTSVSGIIAAVDNSIGTLGVAPRVQLQGFNLLDDNSQQLQK
CCEEECCCCCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCCEEEECCCCEECCCHHHHHH
DWLYALGGNAVTADNRVFNQSYGMSLVDPEGANGLDQVQLDRLFEQRTQQAQGAAYIKAA
HHHHHCCCCEEECCCCEEHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
GNGFSRIAAGNYVLNRTGNLPKLPFENSNIDPSNSNFWNLVVSAINADGVRSSYSSVGSN
CCCHHEHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCHHHHHHHCCCE
VFLSAPGGEYGTDAPAMVTTDLPGCDMGYNRVDDPSTNRLHNNPQLDASCDYNGVMNGTS
EEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SATPNTTGAMALLMSAYPDLSVRDLRDLLARNATRLDANQGPVQINYTAANGQRRQVTGL
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEECCCCCCEEEEEEECCCCCEEECCC
EGWERNAAGLWYSPSYGFGLVDVNKTLASAASHEPLPPLVQLPWQKVTVRDRAVGAIPDV
CCCCCCCCCEEECCCCCEEEEEHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCCCCCCCC
GSSPTRSSTQVDQPLTVEAVQVMVSLDHQRLPDLLIELVSPSGTRSVLLNPNNSLVGQSL
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
DRQQLGYVRTKGLRDMRMLSHKFYGEPAHGEWRLEVTDVANGSRQVSLLDRRTNTRSTLT
CHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHH
ERNNSQPGQLLDWSLRVLGHDAARS
HCCCCCCCCCHHHHHHHHCCHHCCC
>Mature Secondary Structure
MRKTSLALAISALLSALPIASVQANESCTPLTGKEAGLDTGRSSAVRCLPGINPLQDQQW
CCCHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCE
HLLNSGQNAFSPRGGMAGNDLNLWWAHRTEVLGQGINVAVVDDGLAIAHPDLADNVRPGS
EEECCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCCEEEEEECCEEEECCCHHCCCCCCC
KNVVTGGSDPTPTDPDSAHGTSVSGIIAAVDNSIGTLGVAPRVQLQGFNLLDDNSQQLQK
CCEEECCCCCCCCCCCCCCCCCHHEEEEEECCCCCCCCCCCEEEECCCCEECCCHHHHHH
DWLYALGGNAVTADNRVFNQSYGMSLVDPEGANGLDQVQLDRLFEQRTQQAQGAAYIKAA
HHHHHCCCCEEECCCCEEHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEC
GNGFSRIAAGNYVLNRTGNLPKLPFENSNIDPSNSNFWNLVVSAINADGVRSSYSSVGSN
CCCHHEHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCHHHHHHHCCCE
VFLSAPGGEYGTDAPAMVTTDLPGCDMGYNRVDDPSTNRLHNNPQLDASCDYNGVMNGTS
EEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SATPNTTGAMALLMSAYPDLSVRDLRDLLARNATRLDANQGPVQINYTAANGQRRQVTGL
CCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEECCCCCCEEEEEEECCCCCEEECCC
EGWERNAAGLWYSPSYGFGLVDVNKTLASAASHEPLPPLVQLPWQKVTVRDRAVGAIPDV
CCCCCCCCCEEECCCCCEEEEEHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCCCCCCCC
GSSPTRSSTQVDQPLTVEAVQVMVSLDHQRLPDLLIELVSPSGTRSVLLNPNNSLVGQSL
CCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
DRQQLGYVRTKGLRDMRMLSHKFYGEPAHGEWRLEVTDVANGSRQVSLLDRRTNTRSTLT
CHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCEEEEEECCCCCCHHHHH
ERNNSQPGQLLDWSLRVLGHDAARS
HCCCCCCCCCHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1468618 [H]