Click here to switch to the map view.

The map label for this gene is sapD [H]

Identifier: 145299381

GI number: 145299381

Start: 2591264

End: 2592262

Strand: Direct

Name: sapD [H]

Synonym: ASA_2430

Alternate gene names: 145299381

Gene position: 2591264-2592262 (Clockwise)

Preceding gene: 145299380

Following gene: 145299382

Centisome position: 55.11

GC content: 59.16

Gene sequence:

>999_bases
ATGCCCTTGCTCGACATACGCAACCTCACCATCGAAATTGACACGCCACAGGGCAAGGTCAAGGCGGTGGACAAGGTGAG
CCTGACCCTGACCGAGGGGGAGATCCGCGGCCTGGTGGGGGAATCCGGCTCCGGCAAGAGCTTGATTGCCAAAGTGATCG
TCGGCATCCAGAAAGACAACTGGACGGTACGTGCCGACCGGATGCGCTTCAACGACATGGATCTGCTGACCATGGCCCCC
AAGGAGCGGCGCCGGATCATGGGCCGCGAGATAGCCATGATCTTTCAGGACCCCATCAGCTGCCTGGATCCGTCCGGGGA
GATTGGCGCCCAGCTGGAAGAGGCTATCCCGACCGATTCGTTTGAAGGGAAATTCTGGCAACGCTTCCAGTGGCGCAAGA
AAAAGGCCATCGCGCTGCTGCACAGGGTCGGCGTCAAGGATCACCGCAAGGTAATGCGCGCCTATCCCCACGAGCTCTCT
GACGGCATGTGTCAGAAGGTGATGATCGCCATGGCCATTGCCAACAAGCCGCGCCTGCTGGTAGCCGATGAGCCCACCAG
CGCCATGGAGTCCACCACCCACTCCCAGATCCTGCGGCTGCTGGACAAGATGAACAAGCTGGGCAACACCACCATTCTCA
TCATCAGCAACGACATTGCCGCCATCGCCAACCTGACCGACACCATCAATGTGATGTACTGCGGCCAGATGGTGGAGGTC
GGTACCCGGGATCAGATCCTGGATACCCCACACCACCCATATACCGATGCCTTGCTCAAGTCCATTCCCGACTTTGACAA
GCTGGTGCGCCACAAGTCGCGACTCGAAACCCTGCCCGGTGTCATTCCACCGCTGCAGCATCTGCCCATAGGTTGCCGAC
TTGGTCCCCGTTGCCCCTATGCCCAGAAGCAGTGCGTACAGACGCCGCTGATGAGCAAGATCAAGGGCCACCAGTTCAGT
TGCCACTTCCCGCTGAACATGGATGAGCCGAAAAAATGA

Upstream 100 bases:

>100_bases
GGACCGTGACCCTGCCGGGTATGGCCATACTGTTCAGCGTGCTGGTAACCAATTTAGTTGGTGAAGGCATCCGTGAAGCA
CTCAAAGAGGGGAATGATTA

Downstream 100 bases:

>100_bases
TGTTCGTTAACGCCCCCGTCAAGGAGCACAGCTTGTGATTGAACCCTCCCTGTTGCAGGTCAGAGGCCTTAGCAAGACCT
ATCAAAATCGCACCGGCCTG

Product: ABC-type peptide transporter, ATP-binding protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPLLDIRNLTIEIDTPQGKVKAVDKVSLTLTEGEIRGLVGESGSGKSLIAKVIVGIQKDNWTVRADRMRFNDMDLLTMAP
KERRRIMGREIAMIFQDPISCLDPSGEIGAQLEEAIPTDSFEGKFWQRFQWRKKKAIALLHRVGVKDHRKVMRAYPHELS
DGMCQKVMIAMAIANKPRLLVADEPTSAMESTTHSQILRLLDKMNKLGNTTILIISNDIAAIANLTDTINVMYCGQMVEV
GTRDQILDTPHHPYTDALLKSIPDFDKLVRHKSRLETLPGVIPPLQHLPIGCRLGPRCPYAQKQCVQTPLMSKIKGHQFS
CHFPLNMDEPKK

Sequences:

>Translated_332_residues
MPLLDIRNLTIEIDTPQGKVKAVDKVSLTLTEGEIRGLVGESGSGKSLIAKVIVGIQKDNWTVRADRMRFNDMDLLTMAP
KERRRIMGREIAMIFQDPISCLDPSGEIGAQLEEAIPTDSFEGKFWQRFQWRKKKAIALLHRVGVKDHRKVMRAYPHELS
DGMCQKVMIAMAIANKPRLLVADEPTSAMESTTHSQILRLLDKMNKLGNTTILIISNDIAAIANLTDTINVMYCGQMVEV
GTRDQILDTPHHPYTDALLKSIPDFDKLVRHKSRLETLPGVIPPLQHLPIGCRLGPRCPYAQKQCVQTPLMSKIKGHQFS
CHFPLNMDEPKK
>Mature_331_residues
PLLDIRNLTIEIDTPQGKVKAVDKVSLTLTEGEIRGLVGESGSGKSLIAKVIVGIQKDNWTVRADRMRFNDMDLLTMAPK
ERRRIMGREIAMIFQDPISCLDPSGEIGAQLEEAIPTDSFEGKFWQRFQWRKKKAIALLHRVGVKDHRKVMRAYPHELSD
GMCQKVMIAMAIANKPRLLVADEPTSAMESTTHSQILRLLDKMNKLGNTTILIISNDIAAIANLTDTINVMYCGQMVEVG
TRDQILDTPHHPYTDALLKSIPDFDKLVRHKSRLETLPGVIPPLQHLPIGCRLGPRCPYAQKQCVQTPLMSKIKGHQFSC
HFPLNMDEPKK

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=329, Percent_Identity=61.7021276595745, Blast_Score=456, Evalue=1e-130,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=42.0731707317073, Blast_Score=270, Evalue=7e-74,
Organism=Escherichia coli, GI48994883, Length=324, Percent_Identity=36.1111111111111, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=37.1951219512195, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI1787500, Length=329, Percent_Identity=34.0425531914894, Blast_Score=190, Evalue=9e-50,
Organism=Escherichia coli, GI145693107, Length=272, Percent_Identity=34.1911764705882, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789962, Length=315, Percent_Identity=31.4285714285714, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1788506, Length=265, Percent_Identity=35.4716981132075, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1787758, Length=305, Percent_Identity=32.4590163934426, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI48994997, Length=261, Percent_Identity=30.2681992337165, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1789890, Length=258, Percent_Identity=28.6821705426357, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787547, Length=267, Percent_Identity=28.0898876404494, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1786398, Length=280, Percent_Identity=27.1428571428571, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081791, Length=290, Percent_Identity=26.8965517241379, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789032, Length=248, Percent_Identity=29.0322580645161, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789891, Length=247, Percent_Identity=29.5546558704453, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789873, Length=206, Percent_Identity=31.5533980582524, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081834, Length=217, Percent_Identity=29.9539170506912, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788450, Length=242, Percent_Identity=28.5123966942149, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787370, Length=260, Percent_Identity=26.1538461538462, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787029, Length=244, Percent_Identity=26.2295081967213, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081709, Length=257, Percent_Identity=23.7354085603113, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082267, Length=244, Percent_Identity=25.8196721311475, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787105, Length=213, Percent_Identity=26.7605633802817, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786703, Length=221, Percent_Identity=25.3393665158371, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789672, Length=259, Percent_Identity=25.0965250965251, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1786345, Length=229, Percent_Identity=28.3842794759825, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788644, Length=267, Percent_Identity=24.3445692883895, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788225, Length=239, Percent_Identity=25.1046025104602, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082268, Length=240, Percent_Identity=26.25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786654, Length=242, Percent_Identity=24.7933884297521, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786253, Length=226, Percent_Identity=25.6637168141593, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1790467, Length=244, Percent_Identity=21.7213114754098, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI193208177, Length=237, Percent_Identity=25.7383966244726, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37348; Mature: 37217

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRNLTIEIDTPQGKVKAVDKVSLTLTEGEIRGLVGESGSGKSLIAKVIVGIQKDN
CCCEEEEEEEEEEECCCCCEEEEEEEEEEEECCHHHHCCCCCCCCHHHHHHHHHHEECCC
WTVRADRMRFNDMDLLTMAPKERRRIMGREIAMIFQDPISCLDPSGEIGAQLEEAIPTDS
EEEEECCEECCCCCEEEECCHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCCC
FEGKFWQRFQWRKKKAIALLHRVGVKDHRKVMRAYPHELSDGMCQKVMIAMAIANKPRLL
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEE
VADEPTSAMESTTHSQILRLLDKMNKLGNTTILIISNDIAAIANLTDTINVMYCGQMVEV
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEEEEECHHHHC
GTRDQILDTPHHPYTDALLKSIPDFDKLVRHKSRLETLPGVIPPLQHLPIGCRLGPRCPY
CCCCHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCH
AQKQCVQTPLMSKIKGHQFSCHFPLNMDEPKK
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
PLLDIRNLTIEIDTPQGKVKAVDKVSLTLTEGEIRGLVGESGSGKSLIAKVIVGIQKDN
CCEEEEEEEEEEECCCCCEEEEEEEEEEEECCHHHHCCCCCCCCHHHHHHHHHHEECCC
WTVRADRMRFNDMDLLTMAPKERRRIMGREIAMIFQDPISCLDPSGEIGAQLEEAIPTDS
EEEEECCEECCCCCEEEECCHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCCC
FEGKFWQRFQWRKKKAIALLHRVGVKDHRKVMRAYPHELSDGMCQKVMIAMAIANKPRLL
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEE
VADEPTSAMESTTHSQILRLLDKMNKLGNTTILIISNDIAAIANLTDTINVMYCGQMVEV
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHEEEEEECHHHHC
GTRDQILDTPHHPYTDALLKSIPDFDKLVRHKSRLETLPGVIPPLQHLPIGCRLGPRCPY
CCCCHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCH
AQKQCVQTPLMSKIKGHQFSCHFPLNMDEPKK
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]