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The map label for this gene is sapC [H]

Identifier: 145299380

GI number: 145299380

Start: 2590371

End: 2591264

Strand: Direct

Name: sapC [H]

Synonym: ASA_2429

Alternate gene names: 145299380

Gene position: 2590371-2591264 (Clockwise)

Preceding gene: 145299379

Following gene: 145299381

Centisome position: 55.09

GC content: 60.74

Gene sequence:

>894_bases
ATGCAAGACAAGACTAGCCTCTACCCCGAGCTCAAGATCCTCTCCCCGCTGGAGCAGACCTGGGCCTCCTATCGCCGCAA
TCCACTGGCAATGGGGGCACTCTGGTGCTTCGTGATCCTGCTGCTCATCACCCTCATTGGCCCGTTGCTGGTGCCCTACG
GCATCGATGATCAACACAGCTCCCGCCTGCTGCTGGCCCCCTCCTGGGCCAACAGCGGCAACATAGACTACTTCCTTGGC
ACAGACGATCTGGGCCGTGACATCCTCTCCCGTCTGGTGGTGGGCGCGCGCTTCACCTTCGGCAATGCCTTGCTGGTGGT
GCTGATCGCCATGGTGGCCGGCACCGCCATCGGCATCCTGGGCGGCATGAGCAAGGGGCTCAAATCGAGCGTACTGCACC
ACCTGCTCGACACCCTGCTCTCCATCCCTTCCCTGCTGCTGACCATCATCATGGTCGCCATTCTGGGGCCAGGCCTGTTC
AACACCCTGATCGCCATCACGCTGGCGCTGATCCCTCCCTTCATCCGGGCGACCTACAACGCCGTTCACACCGAGATGCA
AAAGGAGTACATCATTGCCAGCCGCCTCGATGGATCGCCCCCATTTCGTATCATGCGTCTGGCCATACTGCCGAACATAG
TGGAGACCCTGGTCGCCCAGACCACTCGCACCCTCTCTGCCGCTATCCTCGATATCTCGGCGGTGGGTTTTCTCGGCCTC
GGTGCCCAGTCTCCCCAGCCGGAGTGGGGTGCCATGCTGGCCGACTCGAGCGATCTCATCTATCTCGCCCCCTGGACCGT
GACCCTGCCGGGTATGGCCATACTGTTCAGCGTGCTGGTAACCAATTTAGTTGGTGAAGGCATCCGTGAAGCACTCAAAG
AGGGGAATGATTAA

Upstream 100 bases:

>100_bases
CAGAGCTGCTCACCACCATCATCTATCCGGCGCGGCGCAAAGAACTCTATGCAAAACAAGACTGAACGTGCTCATGGCAT
GACCTGGAGCCAGGAATCCT

Downstream 100 bases:

>100_bases
TGCCCTTGCTCGACATACGCAACCTCACCATCGAAATTGACACGCCACAGGGCAAGGTCAAGGCGGTGGACAAGGTGAGC
CTGACCCTGACCGAGGGGGA

Product: ABC-type peptide transporter, permease protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MQDKTSLYPELKILSPLEQTWASYRRNPLAMGALWCFVILLLITLIGPLLVPYGIDDQHSSRLLLAPSWANSGNIDYFLG
TDDLGRDILSRLVVGARFTFGNALLVVLIAMVAGTAIGILGGMSKGLKSSVLHHLLDTLLSIPSLLLTIIMVAILGPGLF
NTLIAITLALIPPFIRATYNAVHTEMQKEYIIASRLDGSPPFRIMRLAILPNIVETLVAQTTRTLSAAILDISAVGFLGL
GAQSPQPEWGAMLADSSDLIYLAPWTVTLPGMAILFSVLVTNLVGEGIREALKEGND

Sequences:

>Translated_297_residues
MQDKTSLYPELKILSPLEQTWASYRRNPLAMGALWCFVILLLITLIGPLLVPYGIDDQHSSRLLLAPSWANSGNIDYFLG
TDDLGRDILSRLVVGARFTFGNALLVVLIAMVAGTAIGILGGMSKGLKSSVLHHLLDTLLSIPSLLLTIIMVAILGPGLF
NTLIAITLALIPPFIRATYNAVHTEMQKEYIIASRLDGSPPFRIMRLAILPNIVETLVAQTTRTLSAAILDISAVGFLGL
GAQSPQPEWGAMLADSSDLIYLAPWTVTLPGMAILFSVLVTNLVGEGIREALKEGND
>Mature_297_residues
MQDKTSLYPELKILSPLEQTWASYRRNPLAMGALWCFVILLLITLIGPLLVPYGIDDQHSSRLLLAPSWANSGNIDYFLG
TDDLGRDILSRLVVGARFTFGNALLVVLIAMVAGTAIGILGGMSKGLKSSVLHHLLDTLLSIPSLLLTIIMVAILGPGLF
NTLIAITLALIPPFIRATYNAVHTEMQKEYIIASRLDGSPPFRIMRLAILPNIVETLVAQTTRTLSAAILDISAVGFLGL
GAQSPQPEWGAMLADSSDLIYLAPWTVTLPGMAILFSVLVTNLVGEGIREALKEGND

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=292, Percent_Identity=50, Blast_Score=287, Evalue=7e-79,
Organism=Escherichia coli, GI1789964, Length=280, Percent_Identity=40.7142857142857, Blast_Score=194, Evalue=4e-51,
Organism=Escherichia coli, GI1787054, Length=282, Percent_Identity=31.9148936170213, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1787760, Length=268, Percent_Identity=34.3283582089552, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789889, Length=227, Percent_Identity=32.5991189427313, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1787498, Length=276, Percent_Identity=29.7101449275362, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788505, Length=339, Percent_Identity=24.188790560472, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32014; Mature: 32014

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDKTSLYPELKILSPLEQTWASYRRNPLAMGALWCFVILLLITLIGPLLVPYGIDDQHS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SRLLLAPSWANSGNIDYFLGTDDLGRDILSRLVVGARFTFGNALLVVLIAMVAGTAIGIL
CEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGMSKGLKSSVLHHLLDTLLSIPSLLLTIIMVAILGPGLFNTLIAITLALIPPFIRATYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AVHTEMQKEYIIASRLDGSPPFRIMRLAILPNIVETLVAQTTRTLSAAILDISAVGFLGL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAQSPQPEWGAMLADSSDLIYLAPWTVTLPGMAILFSVLVTNLVGEGIREALKEGND
CCCCCCCCCCCEEECCCCEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQDKTSLYPELKILSPLEQTWASYRRNPLAMGALWCFVILLLITLIGPLLVPYGIDDQHS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SRLLLAPSWANSGNIDYFLGTDDLGRDILSRLVVGARFTFGNALLVVLIAMVAGTAIGIL
CEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGMSKGLKSSVLHHLLDTLLSIPSLLLTIIMVAILGPGLFNTLIAITLALIPPFIRATYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AVHTEMQKEYIIASRLDGSPPFRIMRLAILPNIVETLVAQTTRTLSAAILDISAVGFLGL
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GAQSPQPEWGAMLADSSDLIYLAPWTVTLPGMAILFSVLVTNLVGEGIREALKEGND
CCCCCCCCCCCEEECCCCEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]