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The map label for this gene is sapB [H]

Identifier: 145299379

GI number: 145299379

Start: 2589376

End: 2590335

Strand: Direct

Name: sapB [H]

Synonym: ASA_2428

Alternate gene names: 145299379

Gene position: 2589376-2590335 (Clockwise)

Preceding gene: 145299378

Following gene: 145299380

Centisome position: 55.06

GC content: 60.42

Gene sequence:

>960_bases
ATGTTTCTCTATATTCTGCGCCGCATCAGCCTGCTGCTCATTACCCTGCTGGCCCTGACCTTTGTCGCCTACCTGCTGGA
TTATCGGCTCATCGGCCTGCAAGCCAGCTTCTGGAGCGGTTATCCTGACTTTCTGAGCAACATTCTGGACGGGGATCTGG
GGCTTTCCAGTGTCTCTGGTCTACCTGTGCTGGACGAGATCCGCCACTACTTCCCGGCCACCCTGATCCTCTGTGCAACG
GCATTTGCCATCTCGCTGCTGGTGGGCATTCCGCTGGGCACCCTGGCGGCACTCTCACAAGGCAAGCCGCTGGATCTCTC
CATCATGACCGCCGGCCTCATCGGCTACGCTGTACCTGTGTTCTGGCTGGCGTTGCTGGTGGTGATGTTCTTCTCGCTGG
ATCTCGGCTGGTTGCCCGCCTCCGGCCAGATCAGTCTGCTTTATGACGTGCCCTCCATTACCGGCATAGCATTGATCGAC
GTATTGATGAGCCATGAACCCTGGCGCCAGGCGGCGCTGCACGACGCCCTGCGCCACTTGATCCTGCCCTCGCTGGTGCT
GGCGGTGGTGCCCACCACAGAGGTGATCCGCCACGTGCGCAGCTCCCTCATCGACGTGATGAAGCAGAACTACATCAAGG
CAGCCGCAAGCCGTGGTCTCTCCCGTCGGCAGATTGTCTGGCGCCATGGCCTCAAGAATGCCTTGCCCCCCGTGTTGCCG
CTGCTGGGTCTGCAGCTGGGCAGCGTGCTCACCTCCGCCATGATCACGGAGGTGGTGTTCGAGTGGCACGGGATCGGCCG
CTGGCTCATCAGCAGCATAGCCCTGCAGGACTATGCCGCCATCCGTGGCGCCACCCTGGTAGTGGCTGGTTTCGTCATTT
TTACCAGCGTCAGCACAGAGCTGCTCACCACCATCATCTATCCGGCGCGGCGCAAAGAACTCTATGCAAAACAAGACTGA

Upstream 100 bases:

>100_bases
CCCATGCCCTGCGCACCCAGGTCAGTCGCAGCGACATTGAGGGGCTCTCCCTGATGCCTTTTGGCGGCACCGTCTTCTAC
CAAGCACACAGGGAGTAAGC

Downstream 100 bases:

>100_bases
ACGTGCTCATGGCATGACCTGGAGCCAGGAATCCTATGCAAGACAAGACTAGCCTCTACCCCGAGCTCAAGATCCTCTCC
CCGCTGGAGCAGACCTGGGC

Product: ABC-type peptide transporter, permease protein

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MFLYILRRISLLLITLLALTFVAYLLDYRLIGLQASFWSGYPDFLSNILDGDLGLSSVSGLPVLDEIRHYFPATLILCAT
AFAISLLVGIPLGTLAALSQGKPLDLSIMTAGLIGYAVPVFWLALLVVMFFSLDLGWLPASGQISLLYDVPSITGIALID
VLMSHEPWRQAALHDALRHLILPSLVLAVVPTTEVIRHVRSSLIDVMKQNYIKAAASRGLSRRQIVWRHGLKNALPPVLP
LLGLQLGSVLTSAMITEVVFEWHGIGRWLISSIALQDYAAIRGATLVVAGFVIFTSVSTELLTTIIYPARRKELYAKQD

Sequences:

>Translated_319_residues
MFLYILRRISLLLITLLALTFVAYLLDYRLIGLQASFWSGYPDFLSNILDGDLGLSSVSGLPVLDEIRHYFPATLILCAT
AFAISLLVGIPLGTLAALSQGKPLDLSIMTAGLIGYAVPVFWLALLVVMFFSLDLGWLPASGQISLLYDVPSITGIALID
VLMSHEPWRQAALHDALRHLILPSLVLAVVPTTEVIRHVRSSLIDVMKQNYIKAAASRGLSRRQIVWRHGLKNALPPVLP
LLGLQLGSVLTSAMITEVVFEWHGIGRWLISSIALQDYAAIRGATLVVAGFVIFTSVSTELLTTIIYPARRKELYAKQD
>Mature_319_residues
MFLYILRRISLLLITLLALTFVAYLLDYRLIGLQASFWSGYPDFLSNILDGDLGLSSVSGLPVLDEIRHYFPATLILCAT
AFAISLLVGIPLGTLAALSQGKPLDLSIMTAGLIGYAVPVFWLALLVVMFFSLDLGWLPASGQISLLYDVPSITGIALID
VLMSHEPWRQAALHDALRHLILPSLVLAVVPTTEVIRHVRSSLIDVMKQNYIKAAASRGLSRRQIVWRHGLKNALPPVLP
LLGLQLGSVLTSAMITEVVFEWHGIGRWLISSIALQDYAAIRGATLVVAGFVIFTSVSTELLTTIIYPARRKELYAKQD

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=319, Percent_Identity=49.5297805642633, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1789965, Length=341, Percent_Identity=32.258064516129, Blast_Score=200, Evalue=8e-53,
Organism=Escherichia coli, GI1787761, Length=260, Percent_Identity=38.4615384615385, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787053, Length=283, Percent_Identity=31.8021201413428, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1789888, Length=341, Percent_Identity=29.9120234604106, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1787497, Length=280, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788504, Length=262, Percent_Identity=25.5725190839695, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35002; Mature: 35002

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLYILRRISLLLITLLALTFVAYLLDYRLIGLQASFWSGYPDFLSNILDGDLGLSSVSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHCCCCCCHHCCC
LPVLDEIRHYFPATLILCATAFAISLLVGIPLGTLAALSQGKPLDLSIMTAGLIGYAVPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FWLALLVVMFFSLDLGWLPASGQISLLYDVPSITGIALIDVLMSHEPWRQAALHDALRHL
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ILPSLVLAVVPTTEVIRHVRSSLIDVMKQNYIKAAASRGLSRRQIVWRHGLKNALPPVLP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
LLGLQLGSVLTSAMITEVVFEWHGIGRWLISSIALQDYAAIRGATLVVAGFVIFTSVSTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLTTIIYPARRKELYAKQD
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFLYILRRISLLLITLLALTFVAYLLDYRLIGLQASFWSGYPDFLSNILDGDLGLSSVSG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHCCCCCCHHCCC
LPVLDEIRHYFPATLILCATAFAISLLVGIPLGTLAALSQGKPLDLSIMTAGLIGYAVPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
FWLALLVVMFFSLDLGWLPASGQISLLYDVPSITGIALIDVLMSHEPWRQAALHDALRHL
HHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
ILPSLVLAVVPTTEVIRHVRSSLIDVMKQNYIKAAASRGLSRRQIVWRHGLKNALPPVLP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
LLGLQLGSVLTSAMITEVVFEWHGIGRWLISSIALQDYAAIRGATLVVAGFVIFTSVSTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLTTIIYPARRKELYAKQD
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]